CN103005434A - Freeze-dried gastrodia elata chewable tablet manufacturing method - Google Patents

Freeze-dried gastrodia elata chewable tablet manufacturing method Download PDF

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Publication number
CN103005434A
CN103005434A CN2012105185842A CN201210518584A CN103005434A CN 103005434 A CN103005434 A CN 103005434A CN 2012105185842 A CN2012105185842 A CN 2012105185842A CN 201210518584 A CN201210518584 A CN 201210518584A CN 103005434 A CN103005434 A CN 103005434A
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Prior art keywords
freeze
gastrodia elata
drying
rhizoma gastrodiae
slice
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CN2012105185842A
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苏辉
唐宁
黄俐
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SICHUAN XICHENG NATURAL FOODS CO Ltd
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SICHUAN XICHENG NATURAL FOODS CO Ltd
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Priority to CN2012105185842A priority Critical patent/CN103005434A/en
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Abstract

The invention discloses a freeze-dried gastrodia elata chewable tablet manufacturing method, which comprises a cleaning step and a grading step, and also comprises the following steps of: boiling, cooling, slicing, cleaning sheets and freeze-drying in vacuum. Freeze-dried gastrodia elata chewable tablets are dried by a vacuum freeze-drying technology; due to low-temperature vacuum drying, the original color, the original fragrance, the original flavor and the original shape of a product are not damaged; the gastrodia elata chewable tablet which is not added with any additive can be directly taken just as a cookie; under the condition that gastrodin serving as an effective component is not lost, the gastrodin can be absorbed by a human body to the maximum extent; and the nutrition loss caused by steaming, boiling and stewing is reduced.

Description

A kind of freeze-drying gastrodia elata chewable tablets manufacture method
Technical field
The present invention relates to a kind of rhizoma Gastrodiae manufacture method, particularly relate to a kind of freeze-drying gastrodia elata chewable tablets manufacture method.
Background technology
At present, the pharmaceutical preparation that contains rhizoma Gastrodiae is mainly capsule or conventional tablet, and pharmaceutical preparation causes bioavilability lower because speed is slower, can not reach desirable result for the treatment of.
For example application number is CN200810057779.5, publication number is the Chinese invention patent " rhizoma gastrodiae chewable tablet and preparation method thereof " of CN101229325, a kind of chewable tablet is disclosed, take rhizoma Gastrodiae as active component, what also include other will use auxiliary material, comprises filler, adhesive, flavouring, lubricant etc.But this patent has following problem: the rhizoma Gastrodiae that 1, adopts this patent to produce is to adopt the rhizoma Gastrodiae of oven dry to make raw material; The effective ingredient loss of its rhizoma Gastrodiae is more; 2, add a lot of other compositions (such as starch, xylitol, calcium carbonate etc.) in the rhizoma gastrodiae chewable tablet that adopts this patent to produce, cause the effective ingredient of rhizoma Gastrodiae seldom, its effect is not good enough; 3, rhizoma gastrodiae chewable tablet and non-natural day ramie product of adopting this patent to produce.
Summary of the invention
The object of the invention is to overcome the problems referred to above that prior art exists, propose a kind of freeze-drying gastrodia elata chewable tablets manufacture method.The rhizoma gastrodiae chewable tablet that the present invention produces is to adopt Vacuum Freezing ﹠ Drying Technology to carry out drying, owing to be that low-temperature vacuum drying has kept the original color of product, shape not to be damaged; The gastrodia elata slice that does not add any additive is can be as biscuit direct edible, its effective ingredient Gastrodin will be absorbed by the body in the situation of not losing to greatest extent, has reduced boiling, stewed nutritive loss.
The present invention realizes by the following technical solutions:
A kind of freeze-drying gastrodia elata chewable tablets manufacture method comprises cleaning step and classification step, characterized by further comprising following steps:
Boil boiling hot: boiling hot boiling through the rhizoma Gastrodiae after cleaning, the classification successively, the organized enzyme in the passivation rhizoma Gastrodiae, boiling the time of scalding is 10-20 minute, prevents that its effective ingredient runs off;
Cooling: will put into sterilized water and cool off through over-cooking rhizoma Gastrodiae after scalding, be 3-5 hour cool time, guarantees that the central temperature of rhizoma Gastrodiae is reduced to the 18-24 degree;
Section: cooled rhizoma Gastrodiae is being cut into slices, and slice thickness is 6-10mm;
Sheet is cleaned: the gastrodia elata slice after section is carried out surface clean, and the dope on flush away surface cleans, protects look with aseptic citric acid water;
Freeze: the gastrodia elata slice after sheet is cleaned is put into the following freezer of subzero 35 degree and is freezed, and freeze-off time is 2-3 hour, guarantees that gastrodia elata slice can fully freeze;
Vacuum freeze drying: at first the cold well temperature of dryness storehouse is dropped to below-40 ℃, then will freeze good gastrodia elata slice and put into dry vacuum container, this process will prevent that the gastrodia elata slice that has frozen from thawing; Then dryness storehouse is vacuumized, freezed 1 hour in pressure is the dryness storehouse of 40-60Pa, guarantee fully freezing in conjunction with water in the gastrodia elata slice, at this moment, the moisture of gastrodia elata slice is 90%; Then begin lyophilization, 24-25 hour, after finishing, lyophilization carries out again 3-5 hour parsing-desiccation, deliver from godown when pressure is 20-30Pa in the storehouse to be dried, obtaining moisture is the freeze-drying gastrodia elata chewable tablets of 2%-5%.
Described finished product packing warehouse-in step stores indoor temperature less than 20 ° of C for putting into apotheca and carry out preservation obtaining the freeze-drying gastrodia elata chewable tablets after the vacuum freeze drying step, and humidity is less than 75%.
Also be included in the combination step of carrying out between the finished product packing warehouse-in step, described combination step is will be through the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step, sequential combination by section becomes whole front shape of rhizoma Gastrodiae cutting, and whole the rhizoma Gastrodiae that combines carried out vacuum packaging; Described finished product packing warehouse-in step is put into apotheca for whole the rhizoma Gastrodiae that will be combined vacuum packet and install and is carried out preservation, stores indoor temperature less than 20 ° of C, and humidity is less than 75%.
Also be included in and freeze the sabot step of carrying out before the step, the gastrodia elata slice that described sabot step will be cleaned through sheet is evenly arranged on the charging tray, and is not overlapping between the every gastrodia elata slice.
The present invention compared with prior art, its advantage is:
1, the freeze-drying gastrodia elata chewable tablets of the present invention's production is to adopt Vacuum Freezing ﹠ Drying Technology to carry out drying, and the product of production is owing to be that low-temperature vacuum drying has kept the original color of product, shape not to be damaged.And the small product size of drying, drying is dwindled, color and luster does not have the original color and luster of rhizoma Gastrodiae, rhizoma Gastrodiae to harden, do not had the bitter taste of Gastrodin.
2, the freeze-drying gastrodia elata chewable tablets produced of the present invention dry under vacuum and low temperature after volume, shape substantially constant, it is spongy that material is, without drying shrinkage; During rehydration, large with the contact-making surface of water, can in 1 minute, be reduced into rapidly original proterties.The small product size of drying, drying is dwindled, and can't restore in water.
3, the freeze-drying gastrodia elata chewable tablets of the present invention's production adopts vacuum dehydrating at lower temperature, make the nutritional labeling loss of volatile ingredient in the material and heated denaturalization very little, dry under the vacuum simultaneously, oxygen is few, make the material of easy oxidation obtain inhibition, so product of the present invention has been preserved its nutrition to greatest extent.The product that dries, dries is at high temperature dry, and the effective ingredient Gastrodin loss of its thermal sensitivity nutrition and rhizoma Gastrodiae is very large.What problem can be described is exactly that the product that dries, dries can not eaten the Gastrodin bitter taste.
4, the freeze-drying gastrodia elata chewable tablets of the present invention's production is that bright rhizoma Gastrodiae is cut into slices by forming after the vacuum freeze drying, after every freeze-drying gastrodia elata chewable tablets is assembled, can be recovered to original whole shape of rhizoma Gastrodiae.
5, also there is following advantage: a in the freeze-drying gastrodia elata chewable tablets produced of the present invention at instant, the gastrodia elata slice that do not add any additive can be direct edible as biscuit, its effective ingredient Gastrodin will be absorbed by the body in the situation of not losing to greatest extent, reduce boiling, stewed nutritive loss; B, rhizoma gastrodiae chewable tablet also can use conventional methods (stew pigeon, stewed chicken etc.) and eat, and its flavor just rhizoma Gastrodiae soup more drying than tradition is brighter.
Description of drawings
Fig. 1 is process flow diagram of the present invention
Fig. 2 is the invention process 3 process flow diagrams
The specific embodiment
Embodiment 1:
A kind of freeze-drying gastrodia elata chewable tablets manufacture method comprises cleaning step and classification step, characterized by further comprising following steps:
Boil boiling hot: boiling hot boiling through the rhizoma Gastrodiae after cleaning, the classification successively, the organized enzyme in the passivation rhizoma Gastrodiae, boiling the time of scalding is 10 minutes, prevents that its effective ingredient runs off;
Cooling: will put into sterilized water and cool off through over-cooking rhizoma Gastrodiae after scalding, be 3 hours cool time, guarantees that the central temperature of rhizoma Gastrodiae is reduced to 18 degree;
Section: cooled rhizoma Gastrodiae is being cut into slices, and slice thickness is 6mm;
Sheet is cleaned: the gastrodia elata slice after section is carried out surface clean, and the dope on flush away surface cleans, protects look with aseptic citric acid water;
Freeze: the gastrodia elata slice after sheet is cleaned is put into the following freezer of subzero 35 degree and is freezed, and freeze-off time is 2 hours, guarantees that gastrodia elata slice can fully freeze;
Vacuum freeze drying: at first the cold well temperature of dryness storehouse is dropped to below-40 ℃, then will freeze good gastrodia elata slice and put into dry vacuum container, this process will prevent that the gastrodia elata slice that has frozen from thawing; Then dryness storehouse is vacuumized, freezed 1 hour in pressure is the dryness storehouse of 40Pa, guarantee fully freezing in conjunction with water in the gastrodia elata slice, at this moment, the moisture of gastrodia elata slice is 90%; Then begin lyophilization, 24 hours, after finishing, lyophilization carries out again 3 hours parsing-desiccation, deliver from godown when pressure is 20Pa in the storehouse to be dried, obtain moisture and be 5% freeze-drying gastrodia elata chewable tablets.
The present invention is when producing, and the raw material cleaning step is impurity, silt with clear water flush away surface, and also will clean up the foul in its finedraw; Classification step is carried out classification for the mould with standard (concrete gauge size etc.) by diameter, the length of rhizoma Gastrodiae, and rank is that diameter 40mm is following, the above Three Estate of 40-50mm, 50mm.
Embodiment 2:
A kind of freeze-drying gastrodia elata chewable tablets manufacture method comprises cleaning step and classification step, characterized by further comprising following steps:
Boil boiling hot: boiling hot boiling through the rhizoma Gastrodiae after cleaning, the classification successively, the organized enzyme in the passivation rhizoma Gastrodiae, boiling the time of scalding is 15 minutes, prevents that its effective ingredient runs off;
Cooling: will put into sterilized water and cool off through over-cooking rhizoma Gastrodiae after scalding, be 4 hours cool time, guarantees that the central temperature of rhizoma Gastrodiae is reduced to 20 degree;
Section: cooled rhizoma Gastrodiae is being cut into slices, and slice thickness is 8mm;
Sheet is cleaned: the gastrodia elata slice after section is carried out surface clean, and the dope on flush away surface cleans, protects look with aseptic citric acid water;
Freeze: the gastrodia elata slice after sheet is cleaned is put into the following freezer of subzero 35 degree and is freezed, and freeze-off time is 2 hours, guarantees that gastrodia elata slice can fully freeze;
Vacuum freeze drying: at first the cold well temperature of dryness storehouse is dropped to below-40 ℃, then will freeze good gastrodia elata slice and put into dry vacuum container, this process will prevent that the gastrodia elata slice that has frozen from thawing; Then dryness storehouse is vacuumized, freezed 1 hour in pressure is the dryness storehouse of 50Pa, guarantee fully freezing in conjunction with water in the gastrodia elata slice, at this moment, the moisture of gastrodia elata slice is 90%; Then begin lyophilization, 24 hours, after finishing, lyophilization carries out again 4 hours parsing-desiccation, deliver from godown when pressure is 25Pa in the storehouse to be dried, obtain moisture and be 3% freeze-drying gastrodia elata chewable tablets.
Among the present invention, also comprise finished product packing warehouse-in step, described finished product packing warehouse-in step is carried out preservation for the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step is put into apotheca, stores indoor temperature less than 20 ° of C, and humidity is less than 75%.
Among the present invention, also be included in and freeze the sabot step of carrying out before the step, the gastrodia elata slice that described sabot step will be cleaned through sheet is evenly arranged on the charging tray, and is not overlapping between the every gastrodia elata slice.
The present invention is when producing, and the raw material cleaning step is impurity, silt with clear water flush away surface, and also will clean up the foul in its finedraw; Classification step is carried out classification for the mould with standard (concrete gauge size etc.) by diameter, the length of rhizoma Gastrodiae, and rank is that diameter 40mm is following, the above Three Estate of 40-50mm, 50mm.
Embodiment 3:
Be with the difference of embodiment 2:
A kind of freeze-drying gastrodia elata chewable tablets manufacture method comprises cleaning step and classification step, characterized by further comprising following steps:
Boil boiling hot: boiling hot boiling through the rhizoma Gastrodiae after cleaning, the classification successively, the organized enzyme in the passivation rhizoma Gastrodiae, boiling the time of scalding is 20 minutes, prevents that its effective ingredient runs off;
Cooling: will put into sterilized water and cool off through over-cooking rhizoma Gastrodiae after scalding, be 5 hours cool time, guarantees that the central temperature of rhizoma Gastrodiae is reduced to 24 degree;
Section: cooled rhizoma Gastrodiae is being cut into slices, and slice thickness is 10mm;
Sheet is cleaned: the gastrodia elata slice after section is carried out surface clean, and the dope on flush away surface cleans, protects look with aseptic citric acid water;
Freeze: the gastrodia elata slice after sheet is cleaned is put into the following freezer of subzero 35 degree and is freezed, and freeze-off time is 3 hours, guarantees that gastrodia elata slice can fully freeze;
Vacuum freeze drying: at first the cold well temperature of dryness storehouse is dropped to below-40 ℃, then will freeze good gastrodia elata slice and put into dry vacuum container, this process will prevent that the gastrodia elata slice that has frozen from thawing; Then dryness storehouse is vacuumized, freezed 1 hour in pressure is the dryness storehouse of 60Pa, guarantee fully freezing in conjunction with water in the gastrodia elata slice, at this moment, the moisture of gastrodia elata slice is 90%; Then begin lyophilization, 25 hours, after finishing, lyophilization carries out again 5 hours parsing-desiccation, deliver from godown when pressure is 30Pa in the storehouse to be dried, obtain moisture and be 2% freeze-drying gastrodia elata chewable tablets.
Among the present invention, also be included in the combination step of carrying out between the finished product packing warehouse-in step, described combination step is will be through the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step, sequential combination by section becomes whole front shape of rhizoma Gastrodiae cutting, and whole the rhizoma Gastrodiae that combines carried out vacuum packaging; Described finished product packing warehouse-in step is put into apotheca for whole the rhizoma Gastrodiae that will be combined vacuum packet and install and is carried out preservation, stores indoor temperature less than 20 ° of C, and humidity is less than 75%.
Also be included in and freeze the sabot step of carrying out before the step, the gastrodia elata slice that described sabot step will be cleaned through sheet is evenly arranged on the charging tray, and is not overlapping between the every gastrodia elata slice.
The present invention is when producing, can be by the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step, by the order of section, the multi-disc freeze-drying gastrodia elata chewable tablets that each rhizoma Gastrodiae is cut into combines, recover whole front shape of rhizoma Gastrodiae cutting, with anti-oxidation, safe plastic bag vacuum packing.

Claims (4)

1. a freeze-drying gastrodia elata chewable tablets manufacture method comprises cleaning step and classification step, characterized by further comprising following steps:
Boil boiling hot: boiling hot boiling through the rhizoma Gastrodiae after cleaning, the classification successively, the organized enzyme in the passivation rhizoma Gastrodiae, boiling the time of scalding is 10-20 minute;
Cooling: will put into sterilized water and cool off through over-cooking rhizoma Gastrodiae after scalding, be 3-5 hour cool time, guarantees that the central temperature of rhizoma Gastrodiae is reduced to the 18-24 degree;
Section: cooled rhizoma Gastrodiae is being cut into slices, and slice thickness is 6-10mm;
Sheet is cleaned: the gastrodia elata slice after section is carried out surface clean, and the dope on flush away surface cleans, protects look with aseptic citric acid water;
Freeze: the gastrodia elata slice after sheet is cleaned is put into the following freezer of subzero 35 degree and is freezed, and freeze-off time is 2-3 hour, guarantees that gastrodia elata slice can fully freeze;
Vacuum freeze drying: at first the cold well temperature of dryness storehouse is dropped to below-40 ℃, then will freeze good gastrodia elata slice and put into dry vacuum container, this process will prevent that the gastrodia elata slice that has frozen from thawing; Then dryness storehouse is vacuumized, freezed 1 hour in pressure is the dryness storehouse of 40-60Pa, guarantee fully freezing in conjunction with water in the gastrodia elata slice, at this moment, the moisture of gastrodia elata slice is 90%; Then begin lyophilization, 24-25 hour, after finishing, lyophilization carries out again 3-5 hour parsing-desiccation, deliver from godown when pressure is 20-30Pa in the storehouse to be dried, obtaining moisture is the freeze-drying gastrodia elata chewable tablets of 2%-5%.
2. a kind of freeze-drying gastrodia elata chewable tablets manufacture method according to claim 1, it is characterized in that: described finished product packing warehouse-in step is carried out preservation for the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step is put into apotheca, store indoor temperature less than 20 ° of C, humidity is less than 75%.
3. a kind of freeze-drying gastrodia elata chewable tablets manufacture method according to claim 1, it is characterized in that: also be included in the combination step of carrying out before the finished product packing warehouse-in step, described combination step is will be through the freeze-drying gastrodia elata chewable tablets that obtains after the vacuum freeze drying step, sequential combination by section becomes whole front shape of rhizoma Gastrodiae cutting, and whole the rhizoma Gastrodiae that combines carried out vacuum packaging; Described finished product packing warehouse-in step is put into apotheca for whole the rhizoma Gastrodiae that will be combined vacuum packet and install and is carried out preservation, stores indoor temperature less than 20 ° of C, and humidity is less than 75%.
4. a kind of freeze-drying gastrodia elata chewable tablets manufacture method according to claim 1, it is characterized in that: also be included in and freeze the sabot step of carrying out before the step, described sabot step will be evenly arranged on the charging tray through the gastrodia elata slice of sheet cleaning, and is not overlapping between the every gastrodia elata slice.
CN2012105185842A 2012-12-06 2012-12-06 Freeze-dried gastrodia elata chewable tablet manufacturing method Pending CN103005434A (en)

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Cited By (12)

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CN103285247A (en) * 2013-05-15 2013-09-11 安徽广印堂中药股份有限公司 Preparation method of gastrodia elata decoction piece
CN103623250A (en) * 2013-12-10 2014-03-12 程从友 Preparation technology of active freeze-dried rhizoma gastrodiae
CN103704851A (en) * 2013-12-24 2014-04-09 成都通灵中药饮片精选有限公司 Method for preparing lyophilized products
CN104012965A (en) * 2014-05-31 2014-09-03 成都英泊科技有限公司 Preparation method for freeze-dried bamboo weevil health care products
CN104012994A (en) * 2014-05-31 2014-09-03 成都英泊科技有限公司 Preparation method of freeze-dried bamboo weevils
CN104288530A (en) * 2014-09-19 2015-01-21 陕西科技大学 Method for preparing gastrodia elata slices
CN104721593A (en) * 2015-04-02 2015-06-24 贵州同威生物科技有限公司 Fresh gastrodia elata freeze-dried powder and preparation method thereof
CN104012993B (en) * 2014-05-31 2015-08-05 成都英泊科技有限公司 A kind of preparation method of freeze-drying Cyrtotra chelus longimanus (Fabr) lozenge
CN104856177A (en) * 2015-06-07 2015-08-26 四川赤健中药科技有限公司 Gastrodia elata raw juice and preparing method thereof as well as gastrodia elata beverage
CN108783448A (en) * 2018-07-01 2018-11-13 甘肃农业大学 A kind of Herba Cistanches Rhizoma Gastrodiae Composite Chew slice prescription and preparation method
CN109938335A (en) * 2019-04-04 2019-06-28 西北师范大学 A kind of Rhizoma Gastrodiae cynomorium songaricum chewable tablets and preparation method thereof
CN110013012A (en) * 2019-04-11 2019-07-16 四川赤健中药科技有限公司 Fresh Rhizoma Gastrodiae lyophilized cake and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN103285247A (en) * 2013-05-15 2013-09-11 安徽广印堂中药股份有限公司 Preparation method of gastrodia elata decoction piece
CN103285247B (en) * 2013-05-15 2015-01-21 安徽广印堂中药股份有限公司 Preparation method of gastrodia elata decoction piece
CN103623250B (en) * 2013-12-10 2014-09-10 程从友 Preparation technology of active freeze-dried rhizoma gastrodiae
CN103623250A (en) * 2013-12-10 2014-03-12 程从友 Preparation technology of active freeze-dried rhizoma gastrodiae
CN103704851A (en) * 2013-12-24 2014-04-09 成都通灵中药饮片精选有限公司 Method for preparing lyophilized products
CN104012965B (en) * 2014-05-31 2015-05-06 成都英泊科技有限公司 Preparation method for freeze-dried bamboo weevil health care products
CN104012994A (en) * 2014-05-31 2014-09-03 成都英泊科技有限公司 Preparation method of freeze-dried bamboo weevils
CN104012965A (en) * 2014-05-31 2014-09-03 成都英泊科技有限公司 Preparation method for freeze-dried bamboo weevil health care products
CN104012994B (en) * 2014-05-31 2015-05-27 成都英泊科技有限公司 Preparation method of freeze-dried bamboo weevils
CN104012993B (en) * 2014-05-31 2015-08-05 成都英泊科技有限公司 A kind of preparation method of freeze-drying Cyrtotra chelus longimanus (Fabr) lozenge
CN104288530A (en) * 2014-09-19 2015-01-21 陕西科技大学 Method for preparing gastrodia elata slices
CN104721593A (en) * 2015-04-02 2015-06-24 贵州同威生物科技有限公司 Fresh gastrodia elata freeze-dried powder and preparation method thereof
CN104856177A (en) * 2015-06-07 2015-08-26 四川赤健中药科技有限公司 Gastrodia elata raw juice and preparing method thereof as well as gastrodia elata beverage
CN108783448A (en) * 2018-07-01 2018-11-13 甘肃农业大学 A kind of Herba Cistanches Rhizoma Gastrodiae Composite Chew slice prescription and preparation method
CN109938335A (en) * 2019-04-04 2019-06-28 西北师范大学 A kind of Rhizoma Gastrodiae cynomorium songaricum chewable tablets and preparation method thereof
CN110013012A (en) * 2019-04-11 2019-07-16 四川赤健中药科技有限公司 Fresh Rhizoma Gastrodiae lyophilized cake and preparation method thereof

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Application publication date: 20130403