CN102973838A - Capsule for treating chronic kidney failure syndrome - Google Patents
Capsule for treating chronic kidney failure syndrome Download PDFInfo
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Abstract
The invention discloses a capsule for treating a chronic kidney failure syndrome, and belongs to the field of traditional Chinese medicines. The effective constituents of the capsule comprise the following raw materials in parts by weight: 50-65 parts of white paeony root, 45-60 parts of perilla leaf, 42-58 parts of astragalus mongholicus, 38-54 parts of raw rhubarb, 34-50 parts of fructus forsythia, 30-46 parts of acorus calamus, 28-44 parts of lophatherum gracile, 25-40 parts of radix aconiti lateralis preparata, 22-26 parts of oriental wormwood, 18-22 parts of Sichuan fritillary bulb, 15-28 parts of herba leonuri, 12-25 parts of melon seed, 10-22 parts of blackberry lily, 8-18 parts of akebiaquinata, 5-15 parts of radix cyathulae and 3-12 parts of mirabilite powder. According to the invention, the raw materials complement each other, and the capsule is prepared by scientifically mixing the Chinese herbal medicines with the effects of warming the kidney, benefiting the spleen, descending the turbid, regulating the middle warmer, dredging water passage, tonifying the spleen and kidney, dredging the organs, descending the turbid, and promoting diuresis to remove toxic materials, is specially used for treating kidney and spleen-yang deficiency, turbid accumulation, spleen and kidney-yang deficiency, and water retention and toxin predominance, has a very good treatment effect for various complications of the chronic kidney failure syndrome, and can effectively prolong the survival time of a uremia patient and improve the life quality of the patient.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of capsule that is used for the treatment of the depleted syndrome of chronic kidney.
Background technology
Chronic renal failure refers to that various nephropathys cause the renal function irreversibility to go down, until the clinical syndrome that the series of symptoms that afunction occurs and metabolism disorder form is called for short chronic kidney hypofunction, develops into whole latter stage, is the uremia that it has often been said.Uremia is not an independently disease, but the total clinical syndrome of nephropathys in various late period, is that chronic renal failure enters the syndrome that series of clinical manifestations that whole end occurs during the stage forms.
Uremic morbidity base reason, the most common with metabolic acidosis and water, electrolyte balance disorder." uremic acidosis " can occur because of the acatharsia retention of kidney in the acid product of body metabolism such as the materials such as phosphoric acid, sulphuric acid.During renal insufficiency, the adaptive capacity that kidney overloads to sodium or capacity is too much descends gradually, can cause volume load excessive, common subcutaneous dropsy and Celom liquid loading in various degree.Kidney row potassium capability descends gradually, hyperpotassemia occurs easily.Calcium phosphorus is for penetrating disorder, and main manifestations is the too much and calcium deficiency of phosphorus, even can cause secondary hyperparathyroidism.In addition, chronic kidney hypofunction also shows the pathological changes of cardiovascular system, respiratory system, gastrointestinal system, blood system, neuromuscular system and skeleton aspect.
To uremic Therapeutic Method, can only be undertaken by the mode of artificial replacement kidney work, i.e. general said dialysis at present.Dialysis is exactly to replace kidney work, when the patient enters Uremic, kidneys of patients should damage and surpass more than 90%, do not take replacement therapy if at this moment delay always, toxin retains in the body so, also can bring irreversible infringement to other internal organs of health, such as heart, digestive system, skeleton, blood system etc., and uremia be Drug therapy can not curable disease, do not exist and so-calledly can cure uremic " miraculous cure ".
Existing Drug therapy is just alleviated uremia's symptom to a certain extent, as utilizes calcium preparation to resist high potassium to the toxicity of cardiac muscle; Utilize sodium lactate or sodium bicarbonate to promote that potassium ion enters in the cell, antagonism potassium is to the inhibition of heart; Utilize glucose and insulin combination to use, promote that potassium shifts in cell; The potassium diuretic is arranged in oral or injection, promotes kidney row potassium; Oral cation exchange power fat promotes potassium to drain from intestinal; The treatment such as heart tonifying, expander.Hormones, antagonism class medicine that these aspects adopt have certain side effect usually, when alleviating uremia's symptom, also can bring extra burden to health.
Traditional Chinese medical theory is thought, kidney disease be because kidney deficiency of spleen-YANG, aqueous vapor spread unchecked, contain superinverse in the turbid pathogen, the spleen kidney yang declines, the water retention poison contain cause, can only be by regulating body function, activating immune system is alleviated or is recovered, execute to the ill and control, should with warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, warming and recuperating the spleen and kidney, logical dirty the turbid descending, the diuresis Chinese crude drug that rushes down poison carries out prescription.
Summary of the invention
The invention provides a kind of capsule that is used for the treatment of the depleted syndrome of chronic kidney, have warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, diuresis rush down the effect of poison, cures the disease and ask the source treating both the principal and secondary aspects of a disease, and the various complication of uremia are all had fabulous therapeutic effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of capsule that is used for the treatment of the depleted syndrome of chronic kidney, raw material composition and the parts by weight of making described capsule effective ingredient are:
38～54 parts of 42～58 parts of Radix Et Rhizoma Rhei of 45～60 parts of Radix Astragali Preparatas of 50～65 parts of Folium Perillae of the Radix Paeoniae Alba
25～40 parts of 28～44 parts of Radix Aconiti Lateralis Preparata of 30～46 portions of Herba Lophatheris of 34～50 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
12～25 parts of 15～28 parts of Semen Momordicae Charantiaes of 18～32 parts of Herba Leonuris of 22～36 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
3～12 parts of 5～15 parts of mirabilite powders of 8～18 portions of Radix Cyathulaes of 10～22 portions of Caulis Akebiaes of Rhizoma Belamcandae.
Raw material composition and the parts by weight of making described capsule effective ingredient are:
42～50 parts of 45～55 parts of Radix Et Rhizoma Rhei of 48～58 parts of Radix Astragali Preparatas of 52～62 parts of Folium Perillae of the Radix Paeoniae Alba
28～36 parts of 30～40 parts of Radix Aconiti Lateralis Preparata of 33～43 portions of Herba Lophatheris of 36～46 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
15～23 parts of 18～26 parts of Semen Momordicae Charantiaes of 21～29 parts of Herba Leonuris of 25～33 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
5～9 parts of 8～12 parts of mirabilite powders of 10～16 portions of Radix Cyathulaes of 12～18 portions of Caulis Akebiaes of Rhizoma Belamcandae.
Raw material composition and the parts by weight of making described capsule effective ingredient are:
46 parts of 50 parts of Radix Et Rhizoma Rhei of 53 parts of Radix Astragali Preparatas of 57 parts of Folium Perillae of the Radix Paeoniae Alba
32 parts of 35 parts of Radix Aconiti Lateralis Preparata of 38 portions of Herba Lophatheris of 41 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
19 parts of 22 parts of Semen Momordicae Charantiaes of 25 parts of Herba Leonuris of 29 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
7 parts of 10 parts of mirabilite powders of 13 portions of Radix Cyathulaes of 15 portions of Caulis Akebiaes of Rhizoma Belamcandae.
A kind of preparation method that is used for the treatment of the capsule of the depleted syndrome of chronic kidney comprises following processing step:
(1) Radix Astragali Preparata, Radix Et Rhizoma Rhei, Radix Aconiti Lateralis Preparata, Radix Cyathulae are pulverized and grind into powder, cross 160 order fine powders, for subsequent use.
(2) mirabilite powder is immersed in the water of aliquot, dissolve, medicinal liquid is for subsequent use.
(3) Folium Perillae, Fructus Forsythiae, Rhizoma Acori Graminei, Herba Lophatheri, Herba Artemisiae Scopariae, Herba Leonuri, Caulis Akebiae are put into container, add the water of six times of amounts, soak after 8～10 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 5～7 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 60 ℃ of environment of simmer down to.
(4) Radix Paeoniae Alba, Rhizoma Belamcandae, Bulbus Fritillariae Cirrhosae, Semen Momordicae Charantiae are put into container, add the shao-hsing rice wine of four times of amounts, continue after the heated and boiled to soak 4～6 hours, get immersion; The shao-hsing rice wine that adds again triplication in remaining medicinal residues continues after the heated and boiled to soak 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment.
(5) with the fine powder of step (1) gained, the medicinal liquid of step (2) gained, the thick paste that makes with step (3), step (4) mixes, and after stirring, quick-freezing becomes powder, is prepared as the capsule product with modern crafts.
The property of medicine of the used Chinese medicine of the present invention is as follows:
The Radix Paeoniae Alba: bitter in the mouth; Property is put down.Enter liver; Spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving; Yin fluid astringing is received antiperspirant.Cure mainly the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency." not Lu " carries: " clear and coherent blood vessels, slow in, dispelling malignant blood, expelling extravasated blood, the gas that anhydrates, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat when controlling, attacked by pestiferous factors stomachache, lumbago." modern medicine study confirms; the Radix Paeoniae Alba can be regulated immunity; strengthen macrophage and leukocytic phagocytic function; the immunologic function of adjusting T lymphocyte and body fluid; protect the liver, spasmolytic, analgesia, calmness, anti-cold, cooling effect; in addition smooth muscle is had inhibitory action, the effect of enhancing anoxia enduring, antioxidation and resisting fatigue.
Folium Perillae: acrid in the mouth; Warm in nature.Return lung; Spleen; The stomach warp.Expelling cold and relieving exterior syndrome; Dispersing lung-QI and dissipating phlegm; Circulation of qi promoting and in; Antiabortive; Cowfish Eriocheir sinensis poison.Cure mainly exterior syndrome due to wind-cold; Cough with copious phlegm; The gastral cavity distension; Nausea and vomiting; Stomachache is vomited and diarrhoea; The nausea discord; Gestation is disliked cloudy; The ichthyophagy Eriocheir sinensis poisons." book on Chinese herbal medicine converge with speech " carries: " cold expelling gas, lung heat clearing gas, alleviating distention in middle-JIAO gas, antiabortive gas, lower stagnation of QI, the gas that reduces phlegm, be control gas refreshing medicine also." modern medicine study shows that Folium Perillae water extraction liquid can shorten blood clotting time, blood plasma recalcification time and activated partial thromboplastin time, promotes enterokinesia, in addition in addition analgesic, antibacterial, blood glucose increasing and sedation.
Radix Astragali Preparata: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly the cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle is difficult bursts; Or burst and do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " the function that invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting are arranged." modern medicine study confirms; Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generates and improve the multiple pharmacological effect such as body's immunity; can act on from many aspects body, improves the related artery sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the functions such as patients' hemodynamics and vascular endothelial cell.
Radix Et Rhizoma Rhei: bitter in the mouth; Cold in nature.Enter stomach; Large intestine; Liver; Spleen channel.Attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Detoxifcation.Cure mainly the excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; The edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stasis of blood stagnated and suffered from abdominal pain puerperal; WEIJIA is gathered; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald." Japan hanako materia medica " carries: " sharp joint is rushed down and is stopped up stagnant, aqueous vapor for logical all gas of a surname, blood circulation regulating, the extremity unbalanced cold and heat, and warm miasma heat-phlegm, sharp defecation, and apply all furuncle carbuncle poison." modern medicine study confirms; Radix Et Rhizoma Rhei has broad-spectrum antiviral, antibiotic and antimycotic effect; can be used for the control of various inflammation; the effective ingredient of Radix Et Rhizoma Rhei can be eliminated oxygen-derived free radicals; suppress lipid peroxidation; have anti-aging effects, have in addition outstanding adjusting immunologic function, and diseases of urinary system is had clearly prevention and therapeutical effect.
Fructus Forsythiae: bitter in the mouth; Cold nature.Enter lung; The heart; Gallbladder meridian.Heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds.Cure mainly anemopyretic cold; Epidemic febrile disease; The pyretic stranguria urine retention; Carbuncle; Toxic swelling; Scrofula; Goiter; Sore throat.Shennong's Herbal carries: " main cold and heat, scrofula, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat." clinic study shows; Fructus Forsythiae has broad-spectrum antibacterial action; staphylococcus aureus, Hayes dysentery bacterium are had very strong inhibitory action; other pathogenic bacterium, influenza virus, fungus are had certain inhibitory action; contained oleanolic acid has heart tonifying, diuresis and hypotensive activity; Citrin can reduce vascular permeability and fragility, prevents haemolysis, also has in addition that tell in antiinflammatory, town, the anti-liver injury effect.
Rhizoma Acori Graminei: acrid in the mouth; Bitter; Slightly warm in nature.Enter the heart; Liver; Spleen channel.Waking up the patient from unconsciousness by dissipating phlegm; The removing dampness circulation of qi promoting; The sharp numbness of dispeling the wind; Reducing swelling and alleviating pain.Cure mainly the calentura coma; Syncope due to accumulation of phlegm; Forgetful; Tinnitus; Deaf; Abdominal distention; Fasting dysentery; Rheumatic arthralgia; Traumatic injury; The carbuncle scabies." book on Chinese herbal medicine meets former " carries: " the deficiency of heart-QI person should it, tonifying five ZANG-organs, happy hole, logical nine orifices, improve visual and auditory acuity." modern medicine study confirms, Rhizoma Acori Graminei has the unify effect of digestive system of central nervous system, autonomic nervous system, hormonal system, cardiovascular system of regulating.
Herba Lophatheri: sweet in the mouth; Light; Cold in nature.GUIXIN; Small intestinal; Lung; The stomach warp.Heat clearing away; Relieving restlessness; Diuresis.It is thirsty to cure mainly dysphoria with smothery sensation; Aphtha of the mouth and tongue; Gingival swelling and pain; Children's's night crying due to fright in infant; Hot urination; Stranguria with turbid discharge." the SHENGCAO property of medicine standby will " carries: " expectorant is quenched the thirst, except part of the body cavity above the diaphragm housing the heart and lungs fire, and bright eyes, diuresis is controlled nebulousurine, brings down a fever, loose hemorrhoid poison." modern medicine study shows that Herba Lophatheri has significant refrigeration function, can increase the excretion of urine chloride, staphylococcus aureus, Hemolytic streptococcus had inhibitory action, the effect of the blood glucose that raises in addition in addition.
Radix Aconiti Lateralis Preparata: acrid in the mouth; Bitter; Warm in nature; Poisonous.Enter stomach; Liver Channel.Expectorant dispels the wind; The meridian dredging; The detoxifcation analgesia.Curing mainly middle wind-phlegm stops up; Facial hemiparalysis; Migraine; Tetanus; Venom; Scrofula tuberculosis; Carbuncle." book on Chinese herbal medicine converges and says " carries: " by cold phlegm, the violent medicine of getting round by bribery also for recuperating depleted YANG gas, loose YIN-cold." modern medicine study shows; Radix Aconiti Lateralis Preparata can strengthen myocardial contraction; accelerate heart rate, and blood vessel dilating increases blood flow; improve blood circulation; antibody gram, arrhythmia have protective effect to cardiac muscle, cold resistance; improve hypoxia-bearing capability, also has in addition antiinflammatory, analgesia, enhancing immunity, antithrombotic to form, suppress the effects such as lipid peroxidation, slow down aging.
Herba Artemisiae Scopariae: mildly bitter flavor; Little suffering; Cold nature.Enter spleen; Stomach; Urinary bladder channel.Clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly jaundice; Dysuria; The eczema pruritus." Japan hanako materia medica " carries: " control disease when day capable, fanatical, the headache head revolves, wind-eye bitterly, subtertian malaria, woman's lump in the abdomen, and interior damage is weary exhausted." modern medicine study shows; Herba Artemisiae Scopariae can promote gallbladder hidropoiesis and drainage; participate in the metabolism of bile acid, bilirubin, class ester and some poisonous substance; blood fat reducing, coronary artery dilating, promotion fibrinolytic, and the in addition effects such as analgesic, blood pressure lowering, antibiotic, antiinflammatory have remarkable inhibition to the mutagenic action of AFB1; can promote the leukocyte division; increase the leukocyte number simultaneously in addition, improve the immunocompetence of T cell, participates in the effects such as the immunomodulating of body and inducement interferon.
Bulbus Fritillariae Cirrhosae: sweet in the mouth; Bitter; Cold nature.Return lung; Heart channel.Clearing heat and moistening lung; Preventing phlegm from forming and stopping coughing; Mass dissipating and swelling eliminating.Cure mainly the deficiency of the lung; Chronic cough; Cough due to consumptive disease; Cough caused by dryness-heat; Lung abscess; Scrofula; Carbuncle; Acute mastitis." Changsha medicine solution " carries: " property of Bulbus Fritillariae Uninbracteatae bitter cold, the cool gold that expels the heat-evil, the turbid descending expectorant, its power is non-little, right clearing heat in the lung and here praiseworthy unbeaten gastric qi is very." the modern medicine study confirmation, Bulbus Fritillariae Cirrhosae has significant antitussive and phlegm-dispelling functions, significantly suppresses pepsin and stress ulcer, suppresses the central nervous system.
Herba Leonuri: acrid in the mouth; Bitter; Property is little to be advanced.Return liver; Kidney; Pericardium channel.Promoting blood flow to regulate menstruation; Inducing diuresis to remove edema; Heat-clearing and toxic substances removing.Cure mainly menoxenia; Amenorrhea; The vaginal bleeding during pregnancy difficult labour; Retention of placenta; Puerperal blood faints; Abdominal pain due to blood stasis; Traumatic injury; Dysuria; Edema; The carbuncle skin infection." book on Chinese herbal medicine is looked for the truth " carries: " crazy tissue regeneration promoting is removed in the water promoting the circulation of blood that disappears, and the regulating menstruation detoxifcation is for wanting agent behind the tire front tyre." modern medicine study shows; the leonurine that Herba Leonuri is contained etc. has excitation to the uterus; antiplatelet aggregation, coagulation; improve coronary circulation, cardioprotection; strengthen cardiac contractile force; direct excited respiratory center, and the slow intestinal tube tonicity of speeding also has the effects such as maincenter inhibition, bacteriostatic in addition.
Semen Momordicae Charantiae: bitter in the mouth; Sweet; Warm in nature.Enter kidney; Spleen channel.Warming and recuperating the kidney-YANG.Cure mainly insufficiency of kidney-YANG; Frequent micturition; The enuresis; Seminal emission; Sexual impotence.Compendium of Material Medica is carried: " QI invigorating tonifying YANG." modern medicine study shows; Semen Momordicae Charantiae fibre rich, carbohydrate, fatty oil, Fructus Momordicae charantiae glucoside and grips altogether linoleic acid, can improve the gastrointestinal function, reduce gastrointestinal disease or cancer chance occur; the QI invigorating tonifying YANG also has good curative effect to male spermatorrhea and infertility.
Rhizoma Belamcandae: bitter in the mouth; Cold in nature; Poisonous.Enter lung; Liver Channel.Pathogenic fire reducing; Detoxifcation; Loose blood; Expectorant.Cure mainly the sore throat pharyngalgia; Cough with dyspnea; Accumulation and obstruction of sputum; Scrofula tuberculosis; Malaria with splenomegaly; Women's amenorrhea; Carbuncle sore tumefacting virus." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control laryngopharynx swelling and pain, acute throat trouble is closed in pharynx, tonsillitis, and the Zha rib is red and swollen, and root of the tooth is swollen mashed, attacks the diseases such as loose all pyretic toxicity of carbuncle sore." the modern medicine study confirmation, Rhizoma Belamcandae has inhibition and retarding action to some virus in diseases caused by exogenous pathogenic factor and the throat illness.
Caulis Akebiae: bitter in the mouth; Cold in nature; Poisonous.Enter the heart; Small intestinal; Urinary bladder channel.Clearing heart fire; Treating stranguria; Stimulating milk secretion is stimulated the menstrual flow.Cure mainly hot urination; Pouring brimful of tears; Edema; Dysphoria with smothery sensation in the heart; Aphtha of the mouth and tongue; Leucorrhea; Amenorrhea; Puerperal galactostasis; Damp and hot arthralgia pain." Chinese pharmacopoeia is carried: " purge heat pathogenic fire reducing.Control aphtha of the mouth and tongue, hot urination." the modern medicine study confirmation, the contained aristolochic acid A of Caulis Akebiae has the cytophagous phagocytic function of enhancing, can improve cellular immune function, has significant diuresis.
Radix Cyathulae: sweet in the mouth; Little hardship, property is flat.Return liver, kidney channel.Eliminating blood stasis and inducing menstruation; Easing joint movement; Inducing diuresis for treating stranguria syndrome.Be used for the amenorrhea lump in the abdomen; Retention of placenta; Arthralgia; The flaccidity of the lower limbs clonic spasm of the muscle; Injury from falling down." Chinese medicinal herbal " carries: " removing blood stasis descends, and controls to beat and pounces on knife injury, and the effect that relaxes pain is arranged." the modern medicine study confirmation, Radix Cyathulae has obvious analgesic activity, and contained insectean metamorphosis steroid hormone and Herba Cyathulae Prostratae steroid paulownia have the protein assimilation.
Mirabilite powder: salty in the mouth; Bitter; Cold in nature.Return stomach; Lung; Spleen; Kidney; Small intestinal; Three warmers; Large intestine channel.
Purging heat to relax the bowels; Moistening for dryness and softening hard mass; The detumescence of relieving inflammation or internal heat.Cure mainly the excess-heat constipation; Constipation due to dry stool; Stagnant stomachache; Acute appendicitis swells and ache; Acute mastitis; Swelling and pain of hemorrhoid.Modern medicine study shows, Natrii Sulfas can increase enteral moisture, cause mechanical stimulus, promote enterokinesia, reticuloendothelial system to vermiform appendix and spleen has obvious stimulation, strengthen hypertrophy and phagocytic activity, transfer in addition in addition the inherent resistance against diseases of body, accelerate the effects such as lymph generation, detumescence, pain relieving, diuresis.
The present invention compared with prior art has following beneficial effect:
Prescription polarization of the present invention is leaned on mutually, select possess warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, warming and recuperating the spleen and kidney, logical dirty the turbid descending, diuresis rush down the Chinese crude drug of malicious effect, be carefully dished up through the science compatibility and form, specialize in the kidney deficiency of spleen-YANG, turbid pathogen contain, the spleen kidney yang declines, the water retention poison is contained, various complication to chronic kidney depletion all have fabulous therapeutic effect, can effectively prolong the time-to-live of uremic patient, improve Quality of Life of Patients.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of capsule effective ingredient of the present invention forms and weight is:
Radix Paeoniae Alba 62g Folium Perillae 56g Radix Astragali Preparata 53g Radix Et Rhizoma Rhei 50g
Fructus Forsythiae 46g Rhizoma Acori Graminei 42g Herba Lophatheri 39g Radix Aconiti Lateralis Preparata 36g
Herba Artemisiae Scopariae 32g Bulbus Fritillariae Cirrhosae 29g Herba Leonuri 25g Semen Momordicae Charantiae 22g
Rhizoma Belamcandae 19g Caulis Akebiae 16g Radix Cyathulae 12g mirabilite powder 10g.
The processing step of capsule preparation method thereof of the present invention is:
(1) Radix Astragali Preparata, Radix Et Rhizoma Rhei, Radix Aconiti Lateralis Preparata, Radix Cyathulae are pulverized and grind into powder, cross 160 order fine powders, for subsequent use.
(2) mirabilite powder is immersed in the water of aliquot, dissolve, medicinal liquid is for subsequent use.
(3) Folium Perillae, Fructus Forsythiae, Rhizoma Acori Graminei, Herba Lophatheri, Herba Artemisiae Scopariae, Herba Leonuri, Caulis Akebiae are put into container, add the water of six times of amounts, soak after 8～10 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 5～7 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 60 ℃ of environment of simmer down to.
(4) Radix Paeoniae Alba, Rhizoma Belamcandae, Bulbus Fritillariae Cirrhosae, Semen Momordicae Charantiae are put into container, add the shao-hsing rice wine of four times of amounts, continue after the heated and boiled to soak 4～6 hours, get immersion; The shao-hsing rice wine that adds again triplication in remaining medicinal residues continues after the heated and boiled to soak 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment.
(5) with the fine powder of step (1) gained, the medicinal liquid of step (2) gained, the thick paste that makes with step (3), step (4) mixes, and after stirring, quick-freezing becomes powder, is prepared as the capsule product with modern crafts.
Usage and dosage: adult every day 3 times, each 0.5～0.75g, two hours after meal with warm water delivery service; Patient with severe symptoms every day 4 times, each 0.5～1.0g took with warm yellow wine in two hours after meal.7 days is a course for the treatment of, common 3～5 onsets course for the treatment of, 5～7 onsets course for the treatment of of patient with severe symptoms.
Embodiment 2
The raw material of capsule effective ingredient of the present invention forms and weight is:
Radix Paeoniae Alba 57g Folium Perillae 53g Radix Astragali Preparata 50g Radix Et Rhizoma Rhei 46g
Fructus Forsythiae 41g Rhizoma Acori Graminei 38g Herba Lophatheri 35g Radix Aconiti Lateralis Preparata 32g
Herba Artemisiae Scopariae 29g Bulbus Fritillariae Cirrhosae 25g Herba Leonuri 22g Semen Momordicae Charantiae 19g
Rhizoma Belamcandae 15g Caulis Akebiae 13g Radix Cyathulae 10g mirabilite powder 7g.
Capsule preparation method thereof processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of capsule effective ingredient of the present invention forms and weight is:
Radix Paeoniae Alba 54g Folium Perillae 48g Radix Astragali Preparata 45g Radix Et Rhizoma Rhei 42g
Fructus Forsythiae 38g Rhizoma Acori Graminei 35g Herba Lophatheri 32g Radix Aconiti Lateralis Preparata 28g
Herba Artemisiae Scopariae 25g Bulbus Fritillariae Cirrhosae 22g Herba Leonuri 19g Semen Momordicae Charantiae 15g
Rhizoma Belamcandae 13g Caulis Akebiae 10g Radix Cyathulae 8g mirabilite powder 5g.
Capsule preparation method thereof processing step and the usage and dosage of present embodiment are identical with embodiment 1.
Clinical data:
Show through the clinical verification data tracing, capsule of the present invention is the symptom of the depleted various complication of relieve chronic kidney effectively, especially high to the effective percentage of cardiovascular system, blood system and neuromuscular system, be applicable to the treatment of uremic patient, be suitable for clinical application.
Claims (4)
1. capsule that is used for the treatment of the depleted syndrome of chronic kidney is characterized in that: the raw material of making described capsule effective ingredient forms and parts by weight are:
38～54 parts of 42～58 parts of Radix Et Rhizoma Rhei of 45～60 parts of Radix Astragali Preparatas of 50～65 parts of Folium Perillae of the Radix Paeoniae Alba
25～40 parts of 28～44 parts of Radix Aconiti Lateralis Preparata of 30～46 portions of Herba Lophatheris of 34～50 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
12～25 parts of 15～28 parts of Semen Momordicae Charantiaes of 18～32 parts of Herba Leonuris of 22～36 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
3～12 parts of 5～15 parts of mirabilite powders of 8～18 portions of Radix Cyathulaes of 10～22 portions of Caulis Akebiaes of Rhizoma Belamcandae.
2. a kind of capsule that is used for the treatment of the depleted syndrome of chronic kidney according to claim 1 is characterized in that: the raw material of making described capsule effective ingredient forms and parts by weight are:
42～50 parts of 45～55 parts of Radix Et Rhizoma Rhei of 48～58 parts of Radix Astragali Preparatas of 52～62 parts of Folium Perillae of the Radix Paeoniae Alba
28～36 parts of 30～40 parts of Radix Aconiti Lateralis Preparata of 33～43 portions of Herba Lophatheris of 36～46 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
15～23 parts of 18～26 parts of Semen Momordicae Charantiaes of 21～29 parts of Herba Leonuris of 25～33 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
5～9 parts of 8～12 parts of mirabilite powders of 10～16 portions of Radix Cyathulaes of 12～18 portions of Caulis Akebiaes of Rhizoma Belamcandae.
3. a kind of capsule that is used for the treatment of the depleted syndrome of chronic kidney according to claim 1 is characterized in that: the raw material of making described capsule effective ingredient forms and parts by weight are:
46 parts of 50 parts of Radix Et Rhizoma Rhei of 53 parts of Radix Astragali Preparatas of 57 parts of Folium Perillae of the Radix Paeoniae Alba
32 parts of 35 parts of Radix Aconiti Lateralis Preparata of 38 portions of Herba Lophatheris of 41 portions of Rhizoma Acori Gramineis of Fructus Forsythiae
19 parts of 22 parts of Semen Momordicae Charantiaes of 25 parts of Herba Leonuris of 29 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae
7 parts of 10 parts of mirabilite powders of 13 portions of Radix Cyathulaes of 15 portions of Caulis Akebiaes of Rhizoma Belamcandae.
4. preparation method that is used for the treatment of the capsule of the depleted syndrome of chronic kidney is characterized in that: comprise following processing step:
(1) Radix Astragali Preparata, Radix Et Rhizoma Rhei, Radix Aconiti Lateralis Preparata, Radix Cyathulae are pulverized and grind into powder, cross 160 order fine powders, for subsequent use.
(2) mirabilite powder is immersed in the water of aliquot, dissolve, medicinal liquid is for subsequent use.
(3) Folium Perillae, Fructus Forsythiae, Rhizoma Acori Graminei, Herba Lophatheri, Herba Artemisiae Scopariae, Herba Leonuri, Caulis Akebiae are put into container, add the water of six times of amounts, soak after 8～10 hours, get immersion; The water that adds again four times of amounts in remaining medicinal residues soaked after 5～7 hours, got immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.10～1.15 is for subsequent use under 60 ℃ of environment of simmer down to.
(4) Radix Paeoniae Alba, Rhizoma Belamcandae, Bulbus Fritillariae Cirrhosae, Semen Momordicae Charantiae are put into container, add the shao-hsing rice wine of four times of amounts, continue after the heated and boiled to soak 4～6 hours, get immersion; The shao-hsing rice wine that adds again triplication in remaining medicinal residues continues after the heated and boiled to soak 2～3 hours, gets immersion; Merge twice gained immersion, heating evaporation, the thick paste of relative density 1.15～1.20 is for subsequent use under the simmer down to room temperature environment.
(5) with the fine powder of step (1) gained, the medicinal liquid of step (2) gained, the thick paste that makes with step (3), step (4) mixes, and after stirring, quick-freezing becomes powder, is prepared as the capsule product with modern crafts.
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| CN105477416A (en) * | 2015-12-17 | 2016-04-13 | 夏修菲 | Capsule preparation for comprehensive medical nursing and preparation method of capsule preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698174A (en) * | 2012-07-05 | 2012-10-03 | 杨万明 | Drug for treating chronic renal failure and preparation method thereof |
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| CN102698174A (en) * | 2012-07-05 | 2012-10-03 | 杨万明 | Drug for treating chronic renal failure and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 伍新林; 等: "肾衰方治疗慢性肾功能衰竭的临床研究", 《中药材》, vol. 31, no. 5, 31 December 2008 (2008-12-31), pages 796 - 798 * |
| 沙富兴;: "中西医结合治疗慢性肾脏衰竭36例", 《医药论坛杂志》, vol. 25, no. 3, 31 December 2004 (2004-12-31), pages 49 - 50 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105477416A (en) * | 2015-12-17 | 2016-04-13 | 夏修菲 | Capsule preparation for comprehensive medical nursing and preparation method of capsule preparation |
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