CN102698174A - Drug for treating chronic renal failure and preparation method thereof - Google Patents
Drug for treating chronic renal failure and preparation method thereof Download PDFInfo
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- CN102698174A CN102698174A CN2012102298637A CN201210229863A CN102698174A CN 102698174 A CN102698174 A CN 102698174A CN 2012102298637 A CN2012102298637 A CN 2012102298637A CN 201210229863 A CN201210229863 A CN 201210229863A CN 102698174 A CN102698174 A CN 102698174A
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Abstract
The invention relates to a drug for treating chronic renal failure and preparation method thereof. The preparation method comprises the steps: adding water to radix astragali, white atractylodes rhizome, poria cocos, fructus psoraleae, angelica sylvestris, radix sileris, radix platycodi, polygala tenuifolia, gypsum, phillyrin, herba artemisiae scopariae, agastache rugosa, salviae miltiorrhizae, radix paeoniae rubra, radix glycyrrhizae, rheum officinale, semen cannabidis and the like, decocting to obtain decoction, concentrating and then adding conventional auxiliary materials, adding purified water till the content of crude drug is 1g/ml, encapsulating and disinfecting to obtain the oral liquid preparation. The drug can tonify spleen and warm the kidney, diffuse the lung to dispel wind and eliminate dampness, clear heat and remove toxicity, dampness and turbidity, activate blood and remove blood stasis, and expel toxin and relax the bowels. Proved by clinical observation, the effective rate is 66 percent. The drug is natural and clean, safe and non-toxic without dependency.
Description
Technical field
The present invention relates to a kind of medicine of treating chronic kidney hypofunction, particularly a kind of is the Chinese medicine of the treatment chronic kidney hypofunction of crude drug preparation with Chinese medicine.The invention still further relates to the method for preparing of this medicine.
Background technology
Chronic kidney hypofunction is claimed chronic renal insufficiency again, is meant the chronic progressive external excess of the kidney matter infringement that a variety of causes causes, and causes the kidney organic disease; Can not keep its basic function, finally cause the scleroma of kidney bulbec, its function of fibrosis forfeiture; The a series of pathological changes that cause the body metabolism obstacle; pathological changes is involved " digestive system ", many internal organs such as " respiratory system ", cardiovascular, skin are impaired, cause the blood inosine to increase the carbon dioxide combination rate and descend, urotoxin the waste toxins metabolism such as increases and does not go out; Accumulate in vivo, can develop into uremia when serious.
Main by the nephropathy conventional therapy in the treatment of chronic kidney hypofunction at present.This sick treatment time is long, and expense is high, and average family is difficult for bearing.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine of treating chronic kidney hypofunction, natural pure, the safety non-toxic of this medicine does not have dependency, is free from side effects.
The method for preparing that this medicine is provided in addition is an another object of the present invention.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Radix Astragali 15-30 Rhizoma Atractylodis Macrocephalae 10-15 Poria 15-20
The windproof 6-9 of Fructus Psoraleae 10-20 Rhizoma alpiniae chinensis 6-9
Radix Platycodonis 6-9 Radix Polygalae 9-12 Gypsum Fibrosum 30-60
Fructus Forsythiae 15-20 Herba Artemisiae Scopariae 15-20 Herba Pogostemonis 15-20
Radix Salviae Miltiorrhizae 15-30 Radix Paeoniae Rubra 6-9 Radix Glycyrrhizae 3-6
Radix Et Rhizoma Rhei 6-15 pockmarks core 15-30.
Can said medicine be processed on the pharmaceutics any dosage form such as tablet, pill, powder, capsule, the present invention is oral liquid preferably.
The concrete method for preparing of above-mentioned each component being processed oral liquid according to the invention is:
With above-mentioned medicaments in part by weight mix homogeneously, decocte with water 2～4 times, each 1～2 hour; Collecting decoction filters, and filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18; Cold preservation is left standstill, and gets supernatant and filters, and adds conventional adjuvant in the filtrating; Mixing, adding purified water is 1g/ml to containing the crude drug amount, oral liquid formulations is processed in embedding, sterilization.
Method for using: oral, each 1 bag, every bag of 500ml, every day three times.
The Radix Astragali, Rhizoma Atractylodis Macrocephalae invigorating spleen to remove dampness among the present invention, the merit that the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are strengthened the QI invigorating diuretic is joined in the Poria promoting diuresis with drugs of tasteless flavour, and Fructus Psoraleae has the kidney warming effect, and Rhizoma Et Radix Notopterygii, windproof matching, bring out the best in each other.The ability diaphoresis, a surname's pore makes toxin go out from fur, and Radix Platycodonis has the effect of lung qi dispersing cough-relieving dispersing and elevation lung qi; Radix Platycodonis is joined the Radix Astragali can make the lung qi foot, toxin is gone out from the respiratory tract metabolism, and strengthened the effect of lung governing skin and hair, Radix Polygalae ability the heart strengthening and the mind tranquilizing; Restoring normal coordination between the heart and kidney has syngignoscism, and Gypsum Fibrosum, Fructus Forsythiae heat-clearing and toxic substances removing are drained the toxin of body accumulation; Herba Artemisiae Scopariae, the turbid heat clearing away sending down the abnormal ascending QI of Herba Pogostemonis dampness removing, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra blood circulation promoting and blood stasis dispelling prevent glomerular sclerosis, fibrosis, Radix Et Rhizoma Rhei, pockmarks core can make toxin separate from stool; Keep free movement of the bowels, Radix Glycyrrhizae can make all medicines coordinate reinforcing body resistance.
More than all medicines share, can invigorate the spleen and warm the kidney, the lung qi dispersing expelling wind and removing dampness, the heat-clearing and toxic substances removing dampness removing is turbid, blood circulation promoting and blood stasis dispelling, the toxin expelling relieving constipation, it is high to be used to treat the chronic kidney hypofunction cure rate, no Western medicine prepn is to side effect such as human internal organ infringements, also drug resistance such as antibiotic-free.
For further investigating the clinical efficacy and the safety of medicine of the present invention, select 3 routine chronic kidney hypofunction patients that the curative effect of medicine of the present invention is carried out clinical observation.
Criterion of therapeutical effect: according to " the clinical research guideline of new Chinese medicine treatment chronic kidney hypofunction " regulation, efficacy determination is main with transference cure, and with reference to change situation such as signs, is divided into healing, produce effects, effective, invalid level Four.Cure: symptom and sign all disappear.Produce effects: symptom and sign are obviously improved.Effectively: symptom and sign have certain improvement.Invalid: symptom and sign all do not have improvement.
Observe 3 routine patients, effective 2 examples, invalid 1 example, total effective rate 66% through treatment.Have no side effect and untoward reaction.
The specific embodiment
Embodiment: get the Radix Astragali 25 kg, Rhizoma Atractylodis Macrocephalae 12kg, Poria 18kg, Fructus Psoraleae 15kg, Rhizoma alpiniae chinensis 8 kg, windproof 8 kg, Radix Platycodonis 8kg, Radix Polygalae 11 kg, Gypsum Fibrosum 50 kg, Fructus Forsythiae 18kg, Herba Artemisiae Scopariae 18kg, Herba Pogostemonis 18kg, Radix Salviae Miltiorrhizae 25 kg, Radix Paeoniae Rubra 8 kg, Radix Glycyrrhizae 4 kg, Radix Et Rhizoma Rhei 12 kg, pockmarks core 25 kg, clean decocte with water 3 times with clear water; Each 1～2 hour, collecting decoction filtered; Filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18, and cold preservation is left standstill, and gets supernatant and filters; Add conventional adjuvant in the filtrating; Mixing, adding purified water is 1g/ml to containing the crude drug amount, oral liquid formulations is processed in embedding, sterilization.
Case history one: Yang Shuan, the woman, 48 years old, examined in March, 2010.The patient is in July, 2009;, the soreness of waist is stranded inappetence, anemia (the sub-6g of color), weak, dizziness etc. because of appearring in gynecologic surgery; No abnormal through gynecologial examination; Occur to feel sick in the back, vomiting, evening polyuria etc. (blood test routine, B ultrasonic, bone are worn, liver, renal function etc.) is diagnosed as chronic kidney hypofunction after examination in hospital, carbamide disease late period.After be in hospital, and 2 dialysis improvements are left hospital weekly.But because of the financial difficulties emergency traditional Chinese medical science.Give top plus-minus treatment after examining, existing every 2-3 week dialysis once.
Claims (3)
1. treat medicine of chronic kidney hypofunction and preparation method thereof for one kind, it is characterized in that:
Medicine according to the invention is that feedstock production obtains by following parts by weight of traditional Chinese medicines:
Radix Astragali 15-30 Rhizoma Atractylodis Macrocephalae 10-15 Poria 15-20
The windproof 6-9 of Fructus Psoraleae 10-20 Rhizoma alpiniae chinensis 6-9
Radix Platycodonis 6-9 Radix Polygalae 9-12 Gypsum Fibrosum 30-60
Fructus Forsythiae 15-20 Herba Artemisiae Scopariae 15-20 Herba Pogostemonis 15-20
Radix Salviae Miltiorrhizae 15-30 Radix Paeoniae Rubra 6-9 Radix Glycyrrhizae 3-6
Radix Et Rhizoma Rhei 6-15 pockmarks core 15-30.
2. medicine of chronic kidney hypofunction according to claim 1 and preparation method thereof, its characteristic is being that described medicine is processed oral liquid.
3. the method for preparing of the medicine of the described treatment chronic kidney hypofunction of claim 2 is: with above-mentioned medicaments in part by weight mix homogeneously, and decocte with water 2～4 times, each 1～2 hour; Collecting decoction filters, and filtrating is condensed into the clear paste of 70 ℃ of relative densities 1.15～1.18; Cold preservation is left standstill, and gets supernatant and filters, and adds conventional adjuvant in the filtrating; Mixing, adding purified water is 1g/ml to containing the crude drug amount, oral liquid formulations is processed in embedding, sterilization.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102298637A CN102698174A (en) | 2012-07-05 | 2012-07-05 | Drug for treating chronic renal failure and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102298637A CN102698174A (en) | 2012-07-05 | 2012-07-05 | Drug for treating chronic renal failure and preparation method thereof |
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| CN102698174A true CN102698174A (en) | 2012-10-03 |
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| CN2012102298637A Pending CN102698174A (en) | 2012-07-05 | 2012-07-05 | Drug for treating chronic renal failure and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973838A (en) * | 2013-01-01 | 2013-03-20 | 张冠军 | Capsule for treating chronic kidney failure syndrome |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1054229A (en) * | 1990-02-20 | 1991-09-04 | 三菱电机株式会社 | Controlling apparatus for indicator lamp of elevator |
| CN1682780A (en) * | 2004-04-14 | 2005-10-19 | 张鸣鸣 | Medicine for treating uaemia and insufficiency of kidney-yang and kidney exhaustion and its preparing method |
-
2012
- 2012-07-05 CN CN2012102298637A patent/CN102698174A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1054229A (en) * | 1990-02-20 | 1991-09-04 | 三菱电机株式会社 | Controlling apparatus for indicator lamp of elevator |
| CN1682780A (en) * | 2004-04-14 | 2005-10-19 | 张鸣鸣 | Medicine for treating uaemia and insufficiency of kidney-yang and kidney exhaustion and its preparing method |
Non-Patent Citations (3)
| Title |
|---|
| 张佩青: "《张琪肾病医案精选》", 31 July 2008, 科学出版社 * |
| 李少华: "中西结合治疗慢性肾衰竭", 《中外医疗》 * |
| 李赛: "慢性肾衰竭中医证治规律研究", 《中国博士学位论文全文数据库》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973838A (en) * | 2013-01-01 | 2013-03-20 | 张冠军 | Capsule for treating chronic kidney failure syndrome |
| CN102973838B (en) * | 2013-01-01 | 2014-06-11 | 张冠军 | Capsule for treating chronic kidney failure syndrome |
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Application publication date: 20121003 |