CN102961578A - Traditional Chinese medicine health care product for improving sleep and preparation method thereof - Google Patents
Traditional Chinese medicine health care product for improving sleep and preparation method thereof Download PDFInfo
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- CN102961578A CN102961578A CN201210481150XA CN201210481150A CN102961578A CN 102961578 A CN102961578 A CN 102961578A CN 201210481150X A CN201210481150X A CN 201210481150XA CN 201210481150 A CN201210481150 A CN 201210481150A CN 102961578 A CN102961578 A CN 102961578A
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Abstract
The invention discloses a traditional Chinese medicine health care product for improving sleep and a preparation method thereof. The traditional Chinese medicine health care product contains the following active pharmaceutical ingredients in parts by weight: 45 parts of spina date seed, 30 parts of lucid ganoderma wall-broken spore powder and 15 parts of radix ophiopogonis. The medicinal composition is a granule taking medicinal and edible raw materials as the components. The medicinal composition disclosed by the invention is expected to achieve the effect of improving sleep and is prepared through a scientific and reasonable production process by taking spina date seed, lucid ganoderma wall-broken spore powder and radix ophiopogonis as main raw materials according to a sleep improvement and health care theory; and the product is definite in function, controllable in quality and safe to take. The preparation method of the medicinal composition is simple, and the preparation process can be finished by conventional equipment.
Description
Technical field
The invention belongs to field of health care products, relate to a kind of pharmaceutical composition of health product, particularly a kind of Chinese medicine health care product for improving sleep and preparation method thereof.
Background technology
The expection of developing drugs combination product reaches and improves the sleep health function.This product take Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder, Radix Ophiopogonis as primary raw material, according to improving sleep health mechanism, adopt scientific and reasonable production technology to process, this product function is clear and definite, and is quality controllable, takes safety.
Sleep disorder is common disease and the simultaneous phenomenon of various diseases, is the result that the plyability cause of disease acts on human body, main manifestations for insomnia, the symptoms such as dream is many, easy fatigues, lassitude, hypomnesis, absent minded, thinking bradykinesia.The present invention is a kind of pure Chinese medicinal preparation, take Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder as monarch drug, helps with Radix Ophiopogonis, and three kinds of composition synergism, resisting fatigue increases immunity, reaches the health care that improves sleep, takes the crowd and can not produce dependency.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine health care product for improving sleep and preparation method thereof, this drug regimen is a kind of take the integration of edible and medicinal herbs raw material as main health product granule, this product take Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder, Radix Ophiopogonis as main composition, synergism, reach the health care that improves sleep, take the crowd and can not produce dependency.
Technical scheme of the present invention is: design a kind of Chinese medicine health care product for improving sleep, it is characterized in that composition and weight proportion thereof that it contains crude drug are: 45 parts of Semen Ziziphi Spinosaes, 30 parts of Sporoderm-broken Ganoderma Lucidum Spore powder, 15 parts of Radix Ophiopogonis.
Above-mentioned a kind of Chinese medicine health care product for improving sleep and preparation method thereof, it may further comprise the steps:
1) by following weight ratio weighting raw materials: 45 parts of Semen Ziziphi Spinosaes, 30 parts of Sporoderm-broken Ganoderma Lucidum Spore powder, 15 parts of Radix Ophiopogonis;
2) with above Semen Ziziphi Spinosae, Radix Ophiopogonis, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is mixed with Sporoderm-broken Ganoderma Lucidum Spore powder, evenly, for subsequent use;
4) dry powder described in the step 3 is added 5 parts of starch, 10 parts of anhydrous glucose, 10 parts of steviosides, mix homogeneously;
5) said mixture is added 80% ethanol soft material processed;
6) granulate arrangement with soft material 14 mesh sieves;
7) packing, warehouse-in get final product.
Advantage of the present invention is: Semen Ziziphi Spinosae is hidden sweet, warm in nature in the prescription of the present invention.Enter spleen, stomach warp.Say in China's medicine book Shennong's Herbal the earliest: " invigorating middle warmer the liver benefiting, hard muscles and bones are helped cloudy gas, and all the merit of Semen Ziziphi Spinosae also." Semen Ziziphi Spinosae has the multiple efficacies such as nourishing the liver, mind tranquilizing and the heart calming, arresting sweating, invigorating the spleen and replenishing QI, is usually used in treating the diseases such as neurasthenia, insomnia; The Ganoderma sweet in the mouth is flat.GUIXIN, lung, liver, kidney channel.Invigorating QI and tranquilization, relieving cough and asthma.Be used for malaise, insomnia cardiopalmus, cough and asthma due to lung deficiency, asthenia is losed heart, anorexia, especially Sporoderm-broken Ganoderma Lucidum Spore powder will be used for neurasthenia, dizzy insomnia, dyspepsia, chronic bronchitis, coronary heart disease, heart stricture of vagina pain, hyperlipidemia, hypertension, hepatitis etc., in addition, still skin there is beautification function, and good disease-prevention health effect is arranged; Radix Ophiopogonis sweet in the mouth, little hardship, cold nature.GUIXIN lung, stomach warp.Be used for that dryness of the lung dry cough, chronic consumptive disease cough, thirsty, the vexed insomnia of Tianjin wound, interior-heat are quenched one's thirst, the dryness of the intestine constipation.Each raw material all plays a role Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder as the primary raw material that improves sleep from different aspects to improving sleep, plays the effect of tranquilizing by nourishing the heart; Assistant is with Radix Ophiopogonis, auxiliary treatment neurasthenia, insomnia.This prescription not only can improve sleep, can also enhancing immunity, other diseases there is auxiliary therapeutic action.In addition, various extracts also contain multivitamin, trace element etc., can improve body immunity, improve body other system function, and the health of human body is had certain assosting effect.
Drug regimen of the present invention with take Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder, Radix Ophiopogonis as primary raw material, for a health product of sleep disorder crowd exploitation.This product is helped with Radix Ophiopogonis take Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder as monarch drug, three kinds of composition synergism, and tranquilizing by nourishing the heart, treatment neurasthenia, insomnia reach the health care that improves sleep.No dependence.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
Described pharmaceutical composition provided by the invention adopts following steps to make:
1) by following weight ratio weighting raw materials: 45 parts of Semen Ziziphi Spinosaes, 30 parts of Sporoderm-broken Ganoderma Lucidum Spore powder, 15 parts of Radix Ophiopogonis;
2) with above Semen Ziziphi Spinosae, Radix Ophiopogonis, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is mixed with Sporoderm-broken Ganoderma Lucidum Spore powder, evenly, for subsequent use;
4) dry powder described in the step 3 is added 5 parts of starch, 10 parts of anhydrous glucose, 10 parts of steviosides, mix homogeneously;
5) said mixture is added 80% ethanol soft material processed;
6) granulate arrangement with soft material 14 mesh sieves;
7) packing, warehouse-in get final product.
The clinical observation of the embodiment of the invention 1 product treatment sleep disorder
1 data and method
1.1 physical data
Select sleep disorder patient 160 examples receive treatment voluntarily, each 80 example of men and women, age 20-40 year.Be divided at random treatment group 1, treatment group 2, treatment group 3, and matched group, every group of 40 examples; Each organizes patient age symptom formation without significant difference, and disease time is the longest 3 years, the shortest January.Has comparability (P〉0.05).
1.2 Therapeutic Method
The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day twice, once a bag, 15 is a course for the treatment of.The prosperous good fortune for the treatment of group 2 usefulness is come board Bulbus Lilii Semen Ziziphi Spinosae capsule, one time 3,3 times on the one; Treatment group 3 usefulness Qi Mei board Fu Meile capsules, every day three times, one time 2.
2 results
2.1 curative effect determinate standard
The Drug efficacy evaluation index is assessed with Sleep Dysfunction Rating Scale in Patients with Insomnia (SDRS), the observation project comprise sleep fully, sleep quality, sleep length, insomnia frequency, insomnia degree and wake up after the index such as uncomfortable.With the SDRS total points the treatment before and after subtract minute rate as the curative effect index.Subtract a minute rate=(total points after baseline total points-treatment)/baseline total points.Subtract a minute rate 〉=80% and be clinical recovery, 50%-79% is produce effects, and 30%-49% is invalid for taking a turn for the better less than 30%.
2.2 therapeutic outcome
| ? | Cure | Produce effects | Take a turn for the better | Invalid | Effective percentage |
| Contrast | ? | ? | ? | 40 | 0 |
| Treatment group 1 | 18 | 12 | 8 | 2 | 95% |
| Treatment group 2 | 14 | 14 | 8 | 4 | 90% |
| Treatment group 3 | 16 | 14 | 6 | 4 | 90% |
3 discuss
Chinese medicine is familiar with the cause of disease of insomnia from improper diet and overtiredness, deficiency of qi and blood, and the insomnia pathogenesis is multi-source, and main pathogenesis shows as negative and positive and do not hand in the modern clinic, YANG failing to enter YIN, although relate to the vital organs of the human body, dirty the most relevant with conscience two, show as void, fire, expectorant, the stasis of blood at pathology.How dirty impaired the Different types of etiopathogenises such as improper diet and overtiredness, internal damage by the excessive seven emotions can simultaneously or successively be attacked body, makes disorder of QI and blood,, thus the patient cause of disease is compound often, syndrome is complicated.Adopting Semen Ziziphi Spinosae, Sporoderm-broken Ganoderma Lucidum Spore powder, Radix Ophiopogonis is primary raw material, can improve autonomic nervous dysfunction, and stabilizing the emotions, anxiety reduction and tense situation are regulated sleep, can also improve the functional status of whole health, improve immunity of organisms.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.
Claims (2)
1. Chinese medicine health care product of be used for improving sleep is characterized in that composition and weight proportion thereof that it contains crude drug are: 45 parts of Semen Ziziphi Spinosaes, 30 parts of Sporoderm-broken Ganoderma Lucidum Spore powder, 15 parts of Radix Ophiopogonis.
2. the preparation method of a kind of Chinese medicine health care product for improving sleep according to claim 1, it may further comprise the steps:
1) by following weight ratio weighting raw materials: 45 parts of Semen Ziziphi Spinosaes, 30 parts of Sporoderm-broken Ganoderma Lucidum Spore powder, 15 parts of Radix Ophiopogonis;
2) with above Semen Ziziphi Spinosae, Radix Ophiopogonis, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is mixed with Sporoderm-broken Ganoderma Lucidum Spore powder, evenly, for subsequent use;
4) dry powder described in the step 3 is added 5 parts of starch, 10 parts of anhydrous glucose, 10 parts of steviosides, mix homogeneously;
5) said mixture is added 80% ethanol soft material processed;
6) granulate arrangement with soft material 14 mesh sieves;
7) packing, warehouse-in get final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210481150XA CN102961578A (en) | 2012-11-23 | 2012-11-23 | Traditional Chinese medicine health care product for improving sleep and preparation method thereof |
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| CN201210481150XA CN102961578A (en) | 2012-11-23 | 2012-11-23 | Traditional Chinese medicine health care product for improving sleep and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105054010A (en) * | 2015-07-23 | 2015-11-18 | 广西仙草堂制药有限责任公司 | Glossy ganoderma health care product capable of improving sleep and preparation method of glossy ganoderma health care product |
| CN105124600A (en) * | 2015-08-24 | 2015-12-09 | 杭州娃哈哈科技有限公司 | Composition with a sleep-improving function and application thereof |
| CN111265621A (en) * | 2020-01-21 | 2020-06-12 | 刘嵘 | A medicinal and edible preparation for treating insomnia, dreaminess, asthenia, dryness and palpitation, and its preparation method |
| CN115104732A (en) * | 2022-06-09 | 2022-09-27 | 广西壮族自治区中国科学院广西植物研究所 | Functional food composition for improving sleep and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711810A (en) * | 2009-12-18 | 2010-05-26 | 威海康博尔生物药业有限公司 | Preparation used for improving sleep and enhancing immunity |
-
2012
- 2012-11-23 CN CN201210481150XA patent/CN102961578A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711810A (en) * | 2009-12-18 | 2010-05-26 | 威海康博尔生物药业有限公司 | Preparation used for improving sleep and enhancing immunity |
Non-Patent Citations (1)
| Title |
|---|
| 赵博等: "麦冬对小鼠镇静催眠作用的初步探讨", 《咸宁学院学报（医学版）》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105054010A (en) * | 2015-07-23 | 2015-11-18 | 广西仙草堂制药有限责任公司 | Glossy ganoderma health care product capable of improving sleep and preparation method of glossy ganoderma health care product |
| CN105124600A (en) * | 2015-08-24 | 2015-12-09 | 杭州娃哈哈科技有限公司 | Composition with a sleep-improving function and application thereof |
| CN111265621A (en) * | 2020-01-21 | 2020-06-12 | 刘嵘 | A medicinal and edible preparation for treating insomnia, dreaminess, asthenia, dryness and palpitation, and its preparation method |
| CN115104732A (en) * | 2022-06-09 | 2022-09-27 | 广西壮族自治区中国科学院广西植物研究所 | Functional food composition for improving sleep and preparation method thereof |
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| CB03 | Change of inventor or designer information |
Inventor after: Li Qiufei Inventor after: Tang Yonghong Inventor after: Qian Bo Inventor after: Gao Xiang Inventor before: Tang Yonghong Inventor before: Qian Bo |
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Application publication date: 20130313 |