CN102961503A - Medicinal composition for improving sleep and strengthening immunity and preparation method thereof - Google Patents
Medicinal composition for improving sleep and strengthening immunity and preparation method thereof Download PDFInfo
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- CN102961503A CN102961503A CN 201210481163 CN201210481163A CN102961503A CN 102961503 A CN102961503 A CN 102961503A CN 201210481163 CN201210481163 CN 201210481163 CN 201210481163 A CN201210481163 A CN 201210481163A CN 102961503 A CN102961503 A CN 102961503A
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Abstract
The invention discloses a medicinal composition for improving sleep and strengthening immunity and a preparation method thereof. The medicinal composition contains the following components in parts by weight: 20 parts of radix astragali, 20 parts of tuckahoe, 30 parts of spina date seed, 20 parts of lucid ganoderma and 10 parts of wolfberry fruit. The medicinal composition capsule is a capsule taking pure traditional Chinese medicines as the components. The medicinal composition capsule disclosed by the invention is expected to achieve the effect of improving sleep and strengthening immunity and is prepared through a scientific and reasonable production process by taking radix astragali, tuckahoe, spina date seed, lucid ganoderma and wolfberry fruit as main raw materials; and the product is definite in function, controllable in quality and safe to take. The preparation method of the medicinal composition capsule is simple, and the preparation process can be finished by conventional equipment.
Description
Technical field
The invention belongs to health product technology field, relate to a kind of pharmaceutical composition for improving sleep, enhancing immunity and preparation method thereof.
Background technology
The expection of developing drugs combination product reaches the health care that improves sleep, enhancing immunity.This product Radix Astragali, Poria, Semen Ziziphi Spinosae, Ganoderma, Fructus Lycii are primary raw material, and be theoretical according to Traditional Chinese health, adopts scientific and reasonable production technology to process, and this product function is clear and definite, and is quality controllable, takes safety.
Insomnia is sleep disorder.Show as difficulty falling asleep, intermittently discontinuous, and wake up prematurely, can not continue again to sleep after waking up, do not have enough sleep, malaise, the asthenia sensation, how not good because of health condition, pain. do not feel like oneself, circadian rhythm is upset.Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study and health, and can increase the weight of or bring out the diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy.Obstinate insomnia brings long-term misery to patient, even forms the dependence to the medicine of sleeping peacefully, and the long-term taking medicine of sleeping peacefully can cause iatrogenic disease.The present invention is a kind of pure Chinese medicinal preparation, and take the Radix Astragali, Poria, Semen Ziziphi Spinosae as monarch drug, assistant is with Ganoderma, five kinds of composition synergism of Fructus Lycii, improve sleep, build up one's resistance to disease, reach the treatment function of improving sleep, enhancing immunity, take safety, can not produce dependency.
Summary of the invention
Purpose of the present invention aims to provide a kind of pharmaceutical composition for improving sleep, enhancing immunity and preparation method thereof, this pharmaceutical composition is a kind of health product capsule of pure Chinese medicine, this product is take the Radix Astragali, Poria, Semen Ziziphi Spinosae as monarch drug, assistant reaches the treatment function of improving sleep, enhancing immunity with Ganoderma, five kinds of composition synergism of Fructus Lycii.
Technical scheme of the present invention is: design a kind of pharmaceutical composition for improving sleep, enhancing immunity, it is characterized in that composition and weight proportion thereof that it contains are: 20 parts of the Radixs Astragali, 20 parts in Poria, 30 parts of Semen Ziziphi Spinosaes, 20 parts of Ganodermas, 10 parts of Fructus Lycii.
The preparation method of described a kind of pharmaceutical composition for improving sleep, enhancing immunity is characterized in that it may further comprise the steps:
1) takes by weighing raw material by following weight ratio: 20 parts of the Radixs Astragali, 20 parts in Poria, 30 parts of Semen Ziziphi Spinosaes, 20 parts of Ganodermas, 10 parts of Fructus Lycii;
2) above-mentioned 5 flavor Chinese medicines are pulverized, crossed 100 mesh sieves, for subsequent use;
3) take by weighing 50 parts anhydrous glucose, pulverized 80 mesh sieves;
4) with step 2) and 3) the raw material mix homogeneously in the mixer of packing into, for subsequent use;
5) capsule filling machine on the said mixture is carried out filling, get final product;
6) inner packing;
7) outer package, product inspection, warehouse-in.
Advantage of the present invention, the Radix Astragali nature and flavor in this component are sweet, tepor.Gui Jing: returning lung, spleen, liver, kidney channel benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, hold in the palm the relevant pharmacological action of effect stilbene invigorating QI to consolidate the body surface resistance effect of skin ulcer granulation promoting, inducing diuresis to remove edema is enhancing human body immunity function, enhancing hemopoietic function.Improve substance metabolism, strengthen the effects such as gonad function, anti-stress, slow down aging.The effect Radixs Astragali such as the Radix Astragali also has heart tonifying, regulates blood pressure, antiviral property myocarditis, protects the liver, antiulcer can significantly increase the total white blood cells in the blood, phagocytic function and the sterilizing ability of promotion neutrophilic granulocyte and macrophage.The Radix Astragali and Wheat Protein can reduce lipid peroxide and liver lipofuscin content in the animal serum.The effect of rise SOD activity can reduce lipid peroxide to biomembranous infringement; The Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming; Semen Ziziphi Spinosae is sweet, according to one's conscience warp; Spleen channel; Liver Channel; Gallbladder meridian.Have mind tranquilizing and the heart calming, nourishing the liver, arresting sweating.Treatment restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, the empty spontaneous perspiration of body, night sweat; Ganoderma is sweet, flat GUIXIN, liver, spleen, lung, the kidney Five Classics.Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, the Ganodermas such as malignant tumor have inhibitory action to nervous system, and blood circulation has blood pressure lowering and strengthens the effect of cardiac contractile force, respiratory system there is phlegm-dispelling functions, in addition, also have hepatoprotective, improve immunologic function, effect such as antibiotic grade.The inhibition of extract energy exciting motion, the mobility is reduced, make the coordination exercise imbalance, present the sick effect in dose-dependent town, hexobarbital sleep interaction energy is curtailed sleep, the central stimulants caffeine be can prolong and spasm and Post-dead duration caused, these results show that Ganoderma is the inhibition effect to maincenter.The Fructus Lycii sweet in the mouth, property suppressing the hyperactive liver warp, kidney channel, lung meridian nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.Contain 14 seed amino acids in the Fructus Lycii, and contain the special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalin, make it have outstanding health-care effect in addition, Fructus Lycii can also improve immunity of organisms, and is quite powerful at everyways such as the strong essence of QI invigorating, nourishing the liver and kidney, slow down aging.This product is take the Radix Astragali, Poria, Semen Ziziphi Spinosae as monarch drug, and assistant is with Ganoderma, Fructus Lycii, and five kinds of composition synergism reach the treatment function of improving sleep, enhancing immunity, no dependence.This prescription not only can improve sleep, enhancing immunity, and other diseases is also had auxiliary therapeutic action.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
The preparation method of described a kind of pharmaceutical composition for improving sleep, enhancing immunity adopts following steps to make:
1) takes by weighing raw material by following weight ratio: 20 parts of the Radixs Astragali, 20 parts in Poria, 30 parts of Semen Ziziphi Spinosaes, 20 parts of Ganodermas, 10 parts of Fructus Lycii;
2) above-mentioned 5 flavor Chinese medicines are pulverized, crossed 100 mesh sieves, for subsequent use;
3) take by weighing 50 parts anhydrous glucose, pulverized 80 mesh sieves;
4) with step 2) and 3) the raw material mix homogeneously in the mixer of packing into, for subsequent use;
5) capsule filling machine on the said mixture is carried out filling, get final product;
6) inner packing;
7) outer package, product inspection, warehouse-in.
The embodiment of the invention 1 this clinical observation that is used for the treatment of the pure Chinese medicine combination capsule for treating insomnia of insomnia
1 data and method
1.1 physical data
Insomniac's 80 examples that selection is received treatment voluntarily are divided into each 20 example for the treatment of group and matched group at random, 10 for the treatment of group men, 10 of woman; Age between 28-60, average 44 years old; 11 of matched group men, 9 of woman; Each organizes patient age symptom formation without significant difference, and disease time is the longest 5 years, and is the shortest 2 years.Has comparability (P〉0.05).The patient does not accept other treatment.
1.2 Therapeutic Method
It is consistent that each organizes Primary Care, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, three of every days twice, one time, 30 ~ 60 is a course for the treatment of.Treatment group 2 Jilin Aodong Yanbian Medicine Industry Co., Ltd's ANSHEN BUNAO YE, one time 10 milliliters, 2 times on the one.6g for the treatment of group 3 Beijing Tongrentang Technology Development Co.ltd. Pharmaceutical Factory's mind-easing tonic bolus with arborvitate seed, 2 times on the one.
2 results
2.1 curative effect determinate standard
Diagnostic criteria
Insomnia weight grade scale: I is slight: sleep is awakening often, or sleep and shakiness, wake up morning too early, but affect work II moderate: the 4h that do not have enough sleep, take weekly the medicine 2 times of sleeping peacefully with more than the 6h, but still can adhere to work, sometimes appearance giddy, dreaminess, weak III weigh: lie awake all night, be difficult to adhere to work, often take the medicine of sleeping peacefully, often with headache, giddy, cardiopalmus, the symptom such as forgetful, irritated, weak.
Criterion is:
Recovery from illness: recover the length of one's sleep normal or Nighttime sleep more than 6h, sleep is dull, and is hale and hearty after waking up;
Produce effects: sleep is clearly better, and increase 3h more than before the length of one's sleep, and Depth of sleep increases;
Good effect: symptom before alleviates, the not enough 3h of the front increase length of one's sleep;
Invalid: insomnia is without obviously improving after the treatment.
2.2 therapeutic outcome
? | Cure | Produce effects | Take a turn for the better | Invalid | Effective percentage |
Matched group | 0 | 0 | 0 | 20 | 0 |
Treatment group 1 | 9 | 6 | 4 | 1 | 95% |
Treatment group 2 | 7 | 7 | 4 | 2 | 90% |
Treatment group 3 | 6 | 8 | 3 | 3 | 85% |
3 discuss
The traditional Chinese medical science thinks that the insomnia main cause has: 1. eating and drinking without temperance, disorder of stomach-QI.Eating and drinking without temperance, taste are impaired, dyspepsia is stagnated, and makes and gives birth to expectorant heat, stop up hold back in, disturb on the phlegm-fire, gastric qi is become estranged, yang-energy floating more in outside unable to sleep soundly then.2. work and rest too injures heart spleen.Grieved then cloudy blood secretly consumes mental derangement; Damage of the spleen then lack of appetite is indigestion and loss of appetite, biochemical weary source, and deficiency of nutrient QI and blood can not be nourished the mind and cause and is insomnia.3. emotional factors, happiness, anger, grief and joy etc. all can cause visceral dysfunction, cause hyperactivity of hesrt-fire and liver-fire, incoordination between the spleen and stomach, and the disease of being insomnia also can cause timidness due to deficiency of the heart and malaise.4. body is empty after being ill, blood deficiency of a specified duration, and old insufficiency of blood causes deficiency of heart-blood, the heart is become homeless foster, irritability and being insomnia.Adopt the present invention to make up and can suppress nervus centralis, tranquilizing the mind improves immunity, comprehensively reaches the effect that improves sleep, enhancing immunity.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.
Claims (2)
1. a pharmaceutical composition that is used for improving sleep, enhancing immunity is characterized in that composition and weight proportion thereof that it contains are: 20 parts of the Radixs Astragali, 20 parts in Poria, 30 parts of Semen Ziziphi Spinosaes, 20 parts of Ganodermas, 10 parts of Fructus Lycii.
2. by the preparation method of the described a kind of pharmaceutical composition for improving sleep, enhancing immunity of claim 1, it may further comprise the steps:
1) takes by weighing raw material by following weight ratio: 20 parts of the Radixs Astragali, 20 parts in Poria, 30 parts of Semen Ziziphi Spinosaes, 20 parts of Ganodermas, 10 parts of Fructus Lycii;
2) above-mentioned 5 flavor Chinese medicines are pulverized, crossed 100 mesh sieves, for subsequent use;
3) take by weighing 50 parts anhydrous glucose, pulverized 80 mesh sieves;
4) with step 2) and 3) the raw material mix homogeneously in the mixer of packing into, for subsequent use;
5) capsule filling machine on the said mixture is carried out filling, get final product;
6) inner packing;
7) outer package, product inspection, warehouse-in.
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CN 201210481163 CN102961503A (en) | 2012-11-23 | 2012-11-23 | Medicinal composition for improving sleep and strengthening immunity and preparation method thereof |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104013690A (en) * | 2014-06-20 | 2014-09-03 | 苏州法莫生物技术有限公司 | Traditional Chinese medicine for improving sleeping |
CN105410508A (en) * | 2014-09-05 | 2016-03-23 | 深圳华大基因研究院 | Health food and preparation method thereof |
CN108391818A (en) * | 2018-05-17 | 2018-08-14 | 西安交通大学 | A kind of composition of strengthen immunity and its preparation method and application |
CN110200277A (en) * | 2019-06-28 | 2019-09-06 | 李曰厚 | The Chinese medicine preparation of Yi Zhong dou jujube blood-nourishing soup |
CN110464796A (en) * | 2019-09-19 | 2019-11-19 | 中南大学湘雅二医院 | It is a kind of for treating and/or preventing the Chinese medicine composition and its preparation method and application of hypoimmunity caused by chemicotherapy |
CN111358907A (en) * | 2020-04-28 | 2020-07-03 | 赖宇 | Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof |
CN113303415A (en) * | 2021-05-29 | 2021-08-27 | 贵州三泓药业股份有限公司 | Beverage and preparation method thereof |
CN113881534A (en) * | 2021-10-27 | 2022-01-04 | 辽宁腾鳌酒业有限公司 | Compound wine for aiding sleep and preparation method thereof |
-
2012
- 2012-11-23 CN CN 201210481163 patent/CN102961503A/en not_active Withdrawn
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104013690A (en) * | 2014-06-20 | 2014-09-03 | 苏州法莫生物技术有限公司 | Traditional Chinese medicine for improving sleeping |
CN105410508A (en) * | 2014-09-05 | 2016-03-23 | 深圳华大基因研究院 | Health food and preparation method thereof |
CN108391818A (en) * | 2018-05-17 | 2018-08-14 | 西安交通大学 | A kind of composition of strengthen immunity and its preparation method and application |
CN110200277A (en) * | 2019-06-28 | 2019-09-06 | 李曰厚 | The Chinese medicine preparation of Yi Zhong dou jujube blood-nourishing soup |
CN110464796A (en) * | 2019-09-19 | 2019-11-19 | 中南大学湘雅二医院 | It is a kind of for treating and/or preventing the Chinese medicine composition and its preparation method and application of hypoimmunity caused by chemicotherapy |
CN111358907A (en) * | 2020-04-28 | 2020-07-03 | 赖宇 | Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof |
CN113303415A (en) * | 2021-05-29 | 2021-08-27 | 贵州三泓药业股份有限公司 | Beverage and preparation method thereof |
CN113881534A (en) * | 2021-10-27 | 2022-01-04 | 辽宁腾鳌酒业有限公司 | Compound wine for aiding sleep and preparation method thereof |
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Application publication date: 20130313 |