CN102727614B - Chinese-western medicine preparation for treating chronic obstructive pulmonary disease - Google Patents
Chinese-western medicine preparation for treating chronic obstructive pulmonary disease Download PDFInfo
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- CN102727614B CN102727614B CN2012102032949A CN201210203294A CN102727614B CN 102727614 B CN102727614 B CN 102727614B CN 2012102032949 A CN2012102032949 A CN 2012102032949A CN 201210203294 A CN201210203294 A CN 201210203294A CN 102727614 B CN102727614 B CN 102727614B
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Abstract
The present invention relates to a preparation for treating chronic obstructive pulmonary disease, and a treatment method thereof. The traditional Chinese drug preparation comprises the following components, by weight, 9 parts of mongolian milkvetch root, 12 parts of Chinese ephedra herb, 12 parts of almond, 9 parts of gypsum, and 15 parts of licorice root. The preparation method comprises: grinding the components according to the ratio, screening, refining and concentrating; dividing the resulting mixture into two parts; respectively adding 0.0125 parts by weight of captopril and 0.005 parts by weight of nifedipine tablets to the two parts to prepare into capsules. With the present invention, 396 chronic obstructive pulmonary disease patients are selected and randomly divided into a treatment group and a control group to carry out treatment comparison observation, comparison results of the treatment results show that the total effective rates of the two group patients show significant difference, the drug therapy effect on the treatment group is definitely better than the drug therapy effect of the traditional treatment method, such that the Chinese-western medicine preparation of the present invention has characteristics of promotional value and low price, and is applicable for widespread common patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine and western medicine prescription for the treatment of chronic obstructive pulmonary disease.
Background technology
Chronic obstructive pulmonary disease is a kind of can the prevention and treatable common disease, it is characterized in that the flow limitation of sustainable existence.Flow limitation is and carries out sexual development; with the increase to deleterious particle or induced gas chronic inflammatory reaction of air flue and lung; acute exacerbation and complication affect the order of severity of patient's overall disease; this sick number of patients is many; mortality rate is high; the social economical burden weight, become the important public health problem that affects human health.
At present, the medicine for the treatment of chronic obstructive pulmonary disease is roughly independent Western medicine or Chinese medicine, and the course for the treatment of is long, takes effect slow, and cost is high.
Summary of the invention
, for above-mentioned prior art, the invention provides a kind of cost low, the Chinese medicine and western medicine prescription of the treatment chronic obstructive pulmonary disease that therapeutic effect is good and fast.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine and western medicine prescription for the treatment of chronic obstructive pulmonary disease, formed by weight by following component: 9 parts of the Radixs Astragali, 12 parts, Herba Ephedrae, 12 parts, Semen Armeniacae Amarum, 9 parts, Gypsum Fibrosum, 15 parts, Radix Glycyrrhizae, with above Chinese medicine grind, sieve, refine concentrated after minutes two parts add respectively 0.005 part of 0.0125 part of captopril, Nifedipine Tablets to make capsule.
In use, respectively take 1 time every day sooner or later, adds while showing effect 1 time at every turn.
Pharmacological effect of the present invention is as follows:
The Radix Astragali: tonifying the lung gas, be used for the lung qi deficient syndrome, table is defended and is mended the solid hyperhidrosis of panting, simultaneously can also preventing cold.Modern medicine study proves, the Radix Astragali has and strengthens and regulate body's immunity, gives birth to erythrocyte and leukocyte, and the former can increase the blood oxygen ability of blood, and excited the breathing, reduce hematoblastic adhesiveness, improves blood flow and become.The latter has antiviral and antibacterial action.
Herba Ephedrae: good antiasthmatic effect is arranged.Be used for the breathing with cough of a variety of causes such as wind and cold, expectorant are turbid, pathogenic heat, person out of breath.
Semen Armeniacae Amarum: enter lung meridian, fall lung qi, the lung qi dispersing of holding concurrently again, have good function of relieving cough and calming asthma.
Gypsum Fibrosum: the cough with asthma of clearing away heat-fire, clear pathogen heap soil or fertilizer over and around the roots lung, abnormal rising of lung-QI is out of breath, relieving cough and asthma.
Radix Glycyrrhizae: the effect that the energy eliminating phlegm and stopping cough is relievingd asthma.
Captopril: can remove the spasm of bronchus and vascular smooth muscle, the effect that has spasmolytic to relieving asthma, promote in addition in addition the effect of expectoration, remove the long-pending expectorant of respiratory tract, keep the unimpeded of respiratory tract, reduce blood pressure.
Nifedipine Tablets: can remove blood vessel and bronchial muscular spasm, improve ventilation, reduce blood pressure.
The invention has the beneficial effects as follows:
1, the antihypertensive drugs of blood vessel dilating smooth muscle is applied on the expansion bronchus smooth muscle, has obtained significant curative effect, compare curative effect with traditional Therapeutic Method better, more stable after more, recurrence still less.
2, strengthening vital QI to eliminate pathogenic factors is consolidated medicine, the Radix Astragali, be applied in the treatment of chronic obstructive pulmonary disease, so the class patient coughs all the year round and consume a large amount of physical abilitys, and a large amount of protein are discharged in long-term expectoration, so class patient body void is become thin, the Radix Astragali has obvious therapeutical effect to above-mentioned mechanism.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
The present invention is the prescription for the treatment of chronic obstructive pulmonary disease, this Chinese medicinal formulae consists of by weight following component: Radix Astragali 9g, Herba Ephedrae 12g, Semen Armeniacae Amarum 12g, Gypsum Fibrosum 9g, Radix Glycyrrhizae 15g with above Chinese medicine grind, sieve, refine concentrated after minutes two parts add respectively captopril 12.5mg, Nifedipine Tablets 5mg to make capsule.
Clinical data: we choose 396 routine patients with chronic obstructive pulmonary diseases and have carried out the treatment paired observation, and are divided at random treatment group and matched group; Treatment group: the man, 134 examples, the female, 64 examples, the age, the mean age was 62.56 years old, medical history at 48-89 years old: 15-38 years, average 28.45 years, complicated hypertension 186 examples;
Matched group: man, 121 examples; The female, 87 examples, the age is at 46-82 years old, 49.60 years old mean age, complicated hypertension 180 examples; The physical data no difference of science of statistics such as its age, sex.
The patient data statistical table:
Therapeutic Method: treatment group medication: Radix Astragali 9g, Herba Ephedrae 12g, Semen Armeniacae Amarum 12g, Gypsum Fibrosum 9g, Radix Glycyrrhizae 15g, with above Chinese medicine grind, sieve, refine concentrated after minutes two parts add respectively captopril 12.5mg, Nifedipine Tablets 5mg to make capsule; Matched group (traditional treatment group) medication: prednisolone, dexamethasone add diprophylline or aminophylline; We, at 24 hours, 72 hours, the 2nd day, the 3rd day, the 4th day, the 5th day, the 6th day, observed respectively the contrast therapy effect on the 7th day to 2 groups of patients.
Curative effect judging standard: symptom disappearance person in 24 hours is remarkable result; Doing well,improving is effective in 72 hours; The unchanged person of symptom was invalid in 3 days to 7 days.
Result:
Two groups of patient treatment effects relatively
There were significant differences (P＜0.05) for two groups of total effective rates, illustrate that the treatment group curative effect of medication definitely significantly is better than traditional Therapeutic Method, for a blank has been filled up in the treatment of chronic obstructive pulmonary disease, therefore has promotional value, particularly applicable especially to the patient of basic unit, medical expense is significantly lower than matched group (P＜0.001), and therefore, this combination of Chinese and Western medicine prescription is the cheap prescription of the outstanding specially good effect for the treatment of chronic obstructive pulmonary disease.
Claims (1)
1. treat the Chinese and western medicinal composition of chronic obstructive pulmonary disease: it is characterized in that: this Chinese medicinal formulae consists of by weight following component: 9 parts of the Radixs Astragali, 12 parts, Herba Ephedrae, 12 parts, Semen Armeniacae Amarum, 9 parts, Gypsum Fibrosum, 15 parts, Radix Glycyrrhizae, with the Chinese medicine of above dosage grind, sieve, refine concentrated after minutes two parts add respectively 0.005 part of 0.0125 part of captopril, Nifedipine Tablets to make capsule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102032949A CN102727614B (en) | 2012-06-20 | 2012-06-20 | Chinese-western medicine preparation for treating chronic obstructive pulmonary disease |
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| CN2012102032949A CN102727614B (en) | 2012-06-20 | 2012-06-20 | Chinese-western medicine preparation for treating chronic obstructive pulmonary disease |
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| CN102727614A CN102727614A (en) | 2012-10-17 |
| CN102727614B true CN102727614B (en) | 2013-11-13 |
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| CN103720819B (en) * | 2013-12-24 | 2016-05-04 | 广州中医药大学 | A kind of Chinese medicine composition for the treatment of COPD in stable phase |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101480437A (en) * | 2008-01-11 | 2009-07-15 | 曾雄辉 | Method for preparing decoction containing ephedra, apricot kernel, gypsum, and licorice |
| CN101869612A (en) * | 2010-06-08 | 2010-10-27 | 江西中成药业集团有限公司 | Maxingshigan oral liquid and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101480437A (en) * | 2008-01-11 | 2009-07-15 | 曾雄辉 | Method for preparing decoction containing ephedra, apricot kernel, gypsum, and licorice |
| CN101869612A (en) * | 2010-06-08 | 2010-10-27 | 江西中成药业集团有限公司 | Maxingshigan oral liquid and preparation method thereof |
Non-Patent Citations (5)
| Title |
|---|
| 《国内慢性肺心病急性期主要病理生理研究和治疗进展》;余利平;《中国医学文摘.内科学》;19981231;第19卷(第6期);613-616 * |
| 《慢性阻塞性肺疾病痰瘀阻肺证大鼠模型的评价》;李泽庚等;《中华中医药学刊》;20111031;第29卷(第10期);2161-2163 * |
| 余利平.《国内慢性肺心病急性期主要病理生理研究和治疗进展》.《中国医学文摘.内科学》.1998,第19卷(第6期),613-616. |
| 李泽庚等.《慢性阻塞性肺疾病痰瘀阻肺证大鼠模型的评价》.《中华中医药学刊》.2011,第29卷(第10期),2161-2163. |
| 李真等.《阻塞性肺气肿》.《呼吸病诊疗全书》.2000,316-327. * |
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