CN102727614A - Chinese-western medicine preparation for treating chronic obstructive pulmonary disease - Google Patents
Chinese-western medicine preparation for treating chronic obstructive pulmonary disease Download PDFInfo
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- CN102727614A CN102727614A CN2012102032949A CN201210203294A CN102727614A CN 102727614 A CN102727614 A CN 102727614A CN 2012102032949 A CN2012102032949 A CN 2012102032949A CN 201210203294 A CN201210203294 A CN 201210203294A CN 102727614 A CN102727614 A CN 102727614A
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Abstract
The present invention relates to a preparation for treating chronic obstructive pulmonary disease, and a treatment method thereof. The traditional Chinese drug preparation comprises the following components, by weight, 9 parts of mongolian milkvetch root, 12 parts of Chinese ephedra herb, 12 parts of almond, 9 parts of gypsum, and 15 parts of licorice root. The preparation method comprises: grinding the components according to the ratio, screening, refining and concentrating; dividing the resulting mixture into two parts; respectively adding 0.0125 parts by weight of captopril and 0.005 parts by weight of nifedipine tablets to the two parts to prepare into capsules. With the present invention, 396 chronic obstructive pulmonary disease patients are selected and randomly divided into a treatment group and a control group to carry out treatment comparison observation, comparison results of the treatment results show that the total effective rates of the two group patients show significant difference, the drug therapy effect on the treatment group is definitely better than the drug therapy effect of the traditional treatment method, such that the Chinese-western medicine preparation of the present invention has characteristics of promotional value and low price, and is applicable for widespread common patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine and western medicine prescription of treating chronic obstructive pulmonary disease.
Background technology
Chronic obstructive pulmonary disease is a kind of can the prevention and treatable common disease, it is characterized in that continuing the flow limitation of existence.Flow limitation is and carries out sexual development; With the increase of air flue and lung to deleterious particle or induced gas chronic inflammatory reaction; Acute exacerbation and complication influence the order of severity of patient's overall disease, and this sufferer patient number is many, and mortality rate is high; Social economy's burden is heavy, has become the important public health problem that influences human health.
At present, the medicine of treatment chronic obstructive pulmonary disease is roughly independent Western medicine or Chinese medicine, and the course of treatment is long, and it is slow to take effect, and cost is high.
Summary of the invention
To above-mentioned prior art, it is low to the invention provides a kind of cost, the Chinese medicine and western medicine prescription of the treatment chronic obstructive pulmonary disease that therapeutic effect is good and fast.
The present invention realizes through following technical scheme:
A kind of Chinese medicine and western medicine prescription of treating chronic obstructive pulmonary disease; Form by weight by following component: 9 parts of the Radixs Astragali; 12 parts in Herba Ephedrae, 12 parts in Semen Armeniacae Amarum, 9 parts in Gypsum Fibrosum; 15 parts in Radix Glycyrrhizae, with above Chinese medicine grind, sieve, refine concentrate the back divide two parts add 0.0125 part of captopril respectively, the nifedipine sheet is processed capsule for 0.005 part.
In use, respectively take 1 time every day sooner or later, adds when showing effect 1 time at every turn.
Pharmacological effect of the present invention is following:
The Radix Astragali: tonifying the lung gas, be used for the lung qi deficient syndrome, table is defended and is mended the solid hyperhidrosis of panting, simultaneously can also preventing cold.Modern medicine study proves that the Radix Astragali has enhancing and regulates body's immunity, gives birth to erythrocyte and leukocyte, and the former can increase the blood oxygen ability of blood, and excited the breathing reduced hematoblastic adhesiveness, improves hemorheology.The latter has antiviral and antibacterial action.
Herba Ephedrae: good antiasthmatic effect is arranged.Be used for the breathing with cough of a variety of causes such as wind and cold, expectorant are turbid, pathogenic heat, person out of breath.
Semen Armeniacae Amarum: go into lung meridian, fall lung qi, the lung qi dispersing of holding concurrently again has good function of relieving cough and calming asthma.
Gypsum Fibrosum: the cough with asthma of clearing away heat-fire, clear pathogen heap soil or fertilizer over and around the roots lung, abnormal rising of lung-QI is out of breath, relieving cough and asthma.
Radix Glycyrrhizae: the effect that the ability eliminating phlegm and stopping cough is relievingd asthma.
Captopril: can remove the spasm of bronchus and vascular smooth muscle, the effect that has spasmolytic to relieving asthma, promote the effect of expectoration in addition in addition, remove the long-pending expectorant of respiratory tract, keep the unimpeded of respiratory tract, bring high blood pressure down.
Nifedipine sheet: can remove blood vessel and bronchial muscular spasm, improve ventilation, bring high blood pressure down.
The invention has the beneficial effects as follows:
1, the antihypertensive drugs with the blood vessel dilating smooth muscle is applied on the expansion bronchus smooth muscle, has obtained significant curative effect, and compare curative effect with traditional treatment better, more stable after more, and recurrence still less.
2, strengthening vital QI to eliminate pathogenic factors is consolidated medicine, the Radix Astragali is applied in the treatment of chronic obstructive pulmonary disease, and therefore a type patient coughs all the year round and consumes a large amount of physical abilitys, and a large amount of protein are discharged in long-term expectoration, so type patient body's void is become thin, the Radix Astragali has the obvious treatment effect to above-mentioned mechanism.
The specific embodiment
Below in conjunction with embodiment the present invention is further specified.
The present invention is the prescription of treatment chronic obstructive pulmonary disease; This Chinese medicinal formulae is made up of following component by weight: Radix Astragali 9g; Herba Ephedrae 12g; Semen Armeniacae Amarum 12g, Gypsum Fibrosum 9g, Radix Glycyrrhizae 15g with above Chinese medicine grind, sieve, refine concentrate the back divide two parts add captopril 12.5mg respectively, nifedipine sheet 5mg processes capsule.
Clinical data: we choose 396 routine patients with chronic obstructive pulmonary diseases and have carried out the treatment paired observation, and are divided into treatment group and matched group at random; The treatment group: the man, 134 examples, the woman, 64 examples, the age, the mean age was 62.56 years old, medical history at 48-89 years old: 15-38 years, average 28.45 years, complicated hypertension 186 examples;
Matched group: man, 121 examples; The woman, 87 examples, the age is at 46-82 years old, 49.60 years old mean age, complicated hypertension 180 examples; Physical data no difference of science of statistics such as its age, sex.
The patient data statistical table:
Therapeutic Method: treatment group medication: Radix Astragali 9g, Herba Ephedrae 12g, Semen Armeniacae Amarum 12g, Gypsum Fibrosum 9g, Radix Glycyrrhizae 15g, with above Chinese medicine grind, sieve, refine concentrate the back divide two parts add captopril 12.5mg respectively, nifedipine sheet 5mg processes capsule; Matched group (traditional treatment group) medication: prednisolone, dexamethasone add diprophylline or aminophylline; We at 24 hours, 72 hours, the 2nd day, the 3rd day, the 4th day, the 5th day, the 6th day, observed the contrast therapy effect on the 7th day respectively to 2 groups of patients.
Curative effect judging standard: symptom disappearance person in 24 hours is a remarkable result; Doing well,improving is effective in 72 hours; Symptom no change person was invalid in 3 days to 7 days.
The result:
Two groups of patient treatment effects relatively
There were significant differences (P＜0.05) for two groups of total effective rates; Explain that treatment group curative effect of medication definitely significantly is better than traditional treatment,, therefore have promotional value for a blank has been filled up in the treatment of chronic obstructive pulmonary disease; Particularly the patient to basic unit is suitable for especially; Medical expense is lower than matched group (P＜0.001) significantly, and therefore, this combination of Chinese and Western medicine prescription is the cheap prescription of the outstanding specially good effect of treatment chronic obstructive pulmonary disease.
Claims (1)
1. treat the Chinese medicine and western medicine prescription of chronic obstructive pulmonary disease: it is characterized in that: this Chinese medicinal formulae is made up of following component by weight: 9 parts of the Radixs Astragali; 12 parts in Herba Ephedrae; 12 parts in Semen Armeniacae Amarum; 9 parts in Gypsum Fibrosum, 15 parts in Radix Glycyrrhizae, with the Chinese medicine of above dosage grind, sieve, refine concentrate the back divide two parts add 0.0125 part of captopril respectively, the nifedipine sheet is processed capsule for 0.005 part.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102032949A CN102727614B (en) | 2012-06-20 | 2012-06-20 | Chinese-western medicine preparation for treating chronic obstructive pulmonary disease |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102032949A CN102727614B (en) | 2012-06-20 | 2012-06-20 | Chinese-western medicine preparation for treating chronic obstructive pulmonary disease |
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| Publication Number | Publication Date |
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| CN102727614A true CN102727614A (en) | 2012-10-17 |
| CN102727614B CN102727614B (en) | 2013-11-13 |
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| CN2012102032949A Expired - Fee Related CN102727614B (en) | 2012-06-20 | 2012-06-20 | Chinese-western medicine preparation for treating chronic obstructive pulmonary disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720819A (en) * | 2013-12-24 | 2014-04-16 | 广州中医药大学 | Traditional Chinese medicinal composition for treating chronic obstructive pulmonary disease in stable phase |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101480437A (en) * | 2008-01-11 | 2009-07-15 | 曾雄辉 | Method for preparing decoction containing ephedra, apricot kernel, gypsum, and licorice |
| CN101869612A (en) * | 2010-06-08 | 2010-10-27 | 江西中成药业集团有限公司 | Maxingshigan oral liquid and preparation method thereof |
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2012
- 2012-06-20 CN CN2012102032949A patent/CN102727614B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101480437A (en) * | 2008-01-11 | 2009-07-15 | 曾雄辉 | Method for preparing decoction containing ephedra, apricot kernel, gypsum, and licorice |
| CN101869612A (en) * | 2010-06-08 | 2010-10-27 | 江西中成药业集团有限公司 | Maxingshigan oral liquid and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 余利平: "《国内慢性肺心病急性期主要病理生理研究和治疗进展》", 《中国医学文摘.内科学》 * |
| 李泽庚等: "《慢性阻塞性肺疾病痰瘀阻肺证大鼠模型的评价》", 《中华中医药学刊》 * |
| 李真等: "《呼吸病诊疗全书》", 31 December 2000 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720819A (en) * | 2013-12-24 | 2014-04-16 | 广州中医药大学 | Traditional Chinese medicinal composition for treating chronic obstructive pulmonary disease in stable phase |
| CN103720819B (en) * | 2013-12-24 | 2016-05-04 | 广州中医药大学 | A kind of Chinese medicine composition for the treatment of COPD in stable phase |
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| CN102727614B (en) | 2013-11-13 |
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