CN102533960A - 一种单细胞基因组分析方法及试剂盒 - Google Patents
一种单细胞基因组分析方法及试剂盒 Download PDFInfo
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Abstract
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Priority Applications (5)
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CN201010619689.8A CN102533960B (zh) | 2010-12-31 | 2010-12-31 | 一种单细胞基因组分析方法及试剂盒 |
EP11853098.9A EP2660331B1 (en) | 2010-12-31 | 2011-12-29 | Method for single cell genome analysis and kit therefor |
US13/976,845 US9238840B2 (en) | 2010-12-31 | 2011-12-29 | Method for single cell genome analysis and kit therefor |
PCT/CN2011/084959 WO2012089148A1 (zh) | 2010-12-31 | 2011-12-29 | 单细胞基因组分析方法及试剂盒 |
HK12110109.3A HK1169454A1 (zh) | 2010-12-31 | 2012-10-12 | 種單細胞基因組分析方法及試劑盒 |
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CN201010619689.8A CN102533960B (zh) | 2010-12-31 | 2010-12-31 | 一种单细胞基因组分析方法及试剂盒 |
Publications (2)
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CN102533960A true CN102533960A (zh) | 2012-07-04 |
CN102533960B CN102533960B (zh) | 2014-04-30 |
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CN201010619689.8A Active CN102533960B (zh) | 2010-12-31 | 2010-12-31 | 一种单细胞基因组分析方法及试剂盒 |
Country Status (5)
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US (1) | US9238840B2 (zh) |
EP (1) | EP2660331B1 (zh) |
CN (1) | CN102533960B (zh) |
HK (1) | HK1169454A1 (zh) |
WO (1) | WO2012089148A1 (zh) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104404034A (zh) * | 2014-12-15 | 2015-03-11 | 赛业健康研究中心(太仓)有限公司 | 利用口腔上皮细胞制作单细胞测序参考品的方法 |
CN104450923A (zh) * | 2014-12-15 | 2015-03-25 | 赛业健康研究中心(太仓)有限公司 | 利用囊胚腔液游离dna检测胚胎染色体异常的方法 |
CN104560950A (zh) * | 2014-11-28 | 2015-04-29 | 深圳市海普洛斯生物科技有限公司 | 一种基于mda的全基因组扩增的方法 |
CN105861486A (zh) * | 2015-01-19 | 2016-08-17 | 深圳华大基因科技服务有限公司 | 从混合核酸中获得目标核酸的方法 |
CN106030307A (zh) * | 2013-12-04 | 2016-10-12 | 美纳里尼硅生物***股份公司 | 用于确定基因组完整性和/或通过确定性限制位点全基因组扩增获得的dna序列的文库质量的方法和试剂盒 |
CN106520997A (zh) * | 2016-12-14 | 2017-03-22 | 南京诺唯赞医疗科技有限公司 | 一种单细胞基因表达定量分析的方法 |
CN110787296A (zh) * | 2018-08-01 | 2020-02-14 | 复旦大学附属肿瘤医院 | 一种用于预防或治疗胰腺癌的药物组合物及检测胰腺癌的试剂盒 |
CN112662748A (zh) * | 2019-10-15 | 2021-04-16 | 骏实生物科技(上海)有限公司 | 用于单细胞dna测序文库质量鉴定的引物对组合、方法和试剂盒 |
CN113584138A (zh) * | 2021-09-07 | 2021-11-02 | 广西壮族自治区妇幼保健院 | 一种对mda单细胞全基因组扩增产物的质控方法 |
CN113684266A (zh) * | 2021-09-10 | 2021-11-23 | 苏州贝康医疗器械有限公司 | 用于单细胞全基因组dna扩增产物质量评价的核酸组合物及方法 |
CN117233393A (zh) * | 2023-11-15 | 2023-12-15 | 四川大学华西医院 | 双重免疫组化染色试剂盒及其在鉴别良恶性胆管上皮肿瘤中的应用 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104114703A (zh) * | 2012-03-30 | 2014-10-22 | 深圳华大基因科技服务有限公司 | 全基因组扩增方法及其应用 |
WO2014043140A1 (en) * | 2012-09-12 | 2014-03-20 | The Regents Of The University Of California | Accurate genome sequencing of single cells by single-stranded amplification and sequencing |
US10227650B2 (en) | 2014-11-14 | 2019-03-12 | Athena Diagnostics, Inc. | Methods to detect a silent carrier of a null allele genotype |
EP3253911B1 (en) * | 2015-02-04 | 2021-01-20 | The University Of British Columbia | Methods and devices for analyzing particles |
WO2017165925A1 (en) * | 2016-03-31 | 2017-10-05 | Reproductive Health Science Limited | Amplification of target sequences |
EP3867402A4 (en) * | 2018-10-17 | 2022-07-13 | Perkinelmer Health Sciences (Australia) Pty Ltd | BAR CODING OF NUCLEIC ACIDS |
US10988815B2 (en) * | 2018-12-17 | 2021-04-27 | National Cheng Kung University | Detective molecule, kit and method for predicting fragrance production in an orchid |
CN111379032A (zh) * | 2018-12-28 | 2020-07-07 | 北京贝瑞和康生物技术有限公司 | 一种用于构建同时实现基因组拷贝数变异检测和基因突变检测的测序文库的方法和试剂盒 |
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EP1109938B1 (en) * | 1998-09-18 | 2002-02-27 | Micromet AG | Dna amplification of a single cell |
US6617137B2 (en) * | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
US7297485B2 (en) * | 2001-10-15 | 2007-11-20 | Qiagen Gmbh | Method for nucleic acid amplification that results in low amplification bias |
US20040229233A1 (en) * | 2002-10-16 | 2004-11-18 | Ngk Insulators, Ltd. | Human housekeeping genes and human-tissue specific genes |
EP1583843B1 (en) * | 2002-12-20 | 2018-07-18 | QIAGEN GmbH | Single primer whole genome amplification |
ATE476523T1 (de) * | 2003-06-17 | 2010-08-15 | Human Genetic Signatures Pty | Verfahren zur genomamplifikation |
US7387876B2 (en) * | 2004-02-27 | 2008-06-17 | President And Fellows Of Harvard College | Amplification of trace amounts of nucleic acids |
JP3972106B2 (ja) * | 2004-03-03 | 2007-09-05 | 大学共同利用機関法人情報・システム研究機構 | ゲノムライブラリー作製方法、および同方法により作製されたゲノムライブラリー |
US20060172314A1 (en) * | 2005-01-31 | 2006-08-03 | Song Min-Sun | Quantification of amplified nucleic acids |
TWI367260B (en) * | 2005-03-18 | 2012-07-01 | Univ Hong Kong Chinese | Method for detecting the presence of a fetus with trisomy 21 in a pregnant woman and kit thereof |
CN101333561A (zh) * | 2007-06-29 | 2008-12-31 | 上海裕隆生物科技有限公司 | 心脑血管疾病易感基因芯片检测试剂盒 |
WO2009049889A1 (en) * | 2007-10-16 | 2009-04-23 | Roche Diagnostics Gmbh | High resolution, high throughput hla genotyping by clonal sequencing |
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ES2560209T3 (es) * | 2009-01-20 | 2016-02-17 | The Board Of Trustees Of The Leland Stanford Junior University | Expresión genética en células individuales para el diagnóstico, pronóstico e identificación de dianas farmacológicas |
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2010
- 2010-12-31 CN CN201010619689.8A patent/CN102533960B/zh active Active
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2011
- 2011-12-29 US US13/976,845 patent/US9238840B2/en active Active
- 2011-12-29 EP EP11853098.9A patent/EP2660331B1/en active Active
- 2011-12-29 WO PCT/CN2011/084959 patent/WO2012089148A1/zh active Application Filing
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2012
- 2012-10-12 HK HK12110109.3A patent/HK1169454A1/zh unknown
Non-Patent Citations (5)
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HK1169454A1 (zh) | 2013-01-25 |
CN102533960B (zh) | 2014-04-30 |
US20140017683A1 (en) | 2014-01-16 |
WO2012089148A1 (zh) | 2012-07-05 |
EP2660331B1 (en) | 2017-10-04 |
EP2660331A1 (en) | 2013-11-06 |
US9238840B2 (en) | 2016-01-19 |
EP2660331A4 (en) | 2015-04-15 |
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