CN102406958B - Preparation method of sterile honey dressing - Google Patents
Preparation method of sterile honey dressing Download PDFInfo
- Publication number
- CN102406958B CN102406958B CN201110393076.1A CN201110393076A CN102406958B CN 102406958 B CN102406958 B CN 102406958B CN 201110393076 A CN201110393076 A CN 201110393076A CN 102406958 B CN102406958 B CN 102406958B
- Authority
- CN
- China
- Prior art keywords
- component
- grams
- preparation
- weight
- honey
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 235000012907 honey Nutrition 0.000 title claims abstract description 42
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 238000002156 mixing Methods 0.000 claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 15
- 239000000835 fiber Substances 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 10
- 238000007765 extrusion coating Methods 0.000 claims abstract description 9
- 235000016887 Leptospermum scoparium Nutrition 0.000 claims description 29
- 240000003553 Leptospermum scoparium Species 0.000 claims description 29
- 238000003756 stirring Methods 0.000 claims description 13
- 239000011248 coating agent Substances 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 9
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims description 8
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims description 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 7
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims description 7
- 239000011734 sodium Substances 0.000 claims description 7
- 229910052708 sodium Inorganic materials 0.000 claims description 7
- 229920001817 Agar Polymers 0.000 claims description 6
- 239000008272 agar Substances 0.000 claims description 6
- 239000004744 fabric Substances 0.000 claims description 6
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 5
- 230000000845 anti-microbial effect Effects 0.000 claims description 5
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 5
- 229940126864 fibroblast growth factor Drugs 0.000 claims description 5
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 5
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- XINQFOMFQFGGCQ-UHFFFAOYSA-L (2-dodecoxy-2-oxoethyl)-[6-[(2-dodecoxy-2-oxoethyl)-dimethylazaniumyl]hexyl]-dimethylazanium;dichloride Chemical compound [Cl-].[Cl-].CCCCCCCCCCCCOC(=O)C[N+](C)(C)CCCCCC[N+](C)(C)CC(=O)OCCCCCCCCCCCC XINQFOMFQFGGCQ-UHFFFAOYSA-L 0.000 claims description 3
- 239000004745 nonwoven fabric Substances 0.000 abstract description 5
- 239000000648 calcium alginate Substances 0.000 abstract description 4
- 235000010410 calcium alginate Nutrition 0.000 abstract description 4
- 229960002681 calcium alginate Drugs 0.000 abstract description 4
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 abstract description 4
- 206010052428 Wound Diseases 0.000 description 15
- 208000027418 Wounds and injury Diseases 0.000 description 15
- 230000000694 effects Effects 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000035876 healing Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010039509 Scab Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a preparation method of a sterile honey dressing, which comprises the following steps: 1. preparing a component A; 2. preparing a component B; 3. preparing a component C; 4. taking calcium alginate fiber nonwoven fabric or medical nonwoven fabric as a component D for later use; and 5. thoroughly and evenly mixing the component A and component B in a high-shear mixer, of which the rotation speed is 3000-3500 rpm, for 10-25 minutes into a semigel state, slowly adding the component C, mixing at a lower rotation speed of 150-200 rpm for 30-45 minutes, putting the component A/B/C mixture material aside for later use, taking 10 square meters of component D, putting the component D in a double-roller extrusion coating machine, and adding the component A/B/C mixture material into the double-roller extrusion coating machine to prepare the sterile honey dressing at 10 DEG C or below, wherein 200-350g of the component A/B/C mixture material is coated on every square meter of the component D.
Description
Technical field
The present invention relates to a kind of preparation method of sterile honey dressing.
Background technology
In current many adjuvants, lack nutrient substance, with regard to some wounds that make, because antibacterial infects, cause wound cannot produce metabolic function like this, make wound be difficult to healing.
Summary of the invention
The invention provides a kind of preparation method of sterile honey dressing, it not only has stronger sterilizing ability, and can enhance metabolism, and wound can be healed very soon.
The present invention has adopted following technical scheme: a kind of preparation method of sterile honey dressing, and it comprises the following steps:
Step 1, preparation A component: get 1000 grams of Manuka honeys, in Manuka honey, contain antimicrobial component UMF, the weight of UMF accounts for 6-10% of Manuka honey gross weight, adds 10-25 grams of pure water and through the mixing for standby use that stirs, be prepared into A component again in Manuka honey;
Step 2, preparation B component: the weight of getting cross-linked carboxymethyl fiber sodium is that 50-100 grams, the weight of sodium carboxymethyl cellulose are standby after 100-150 grams of mixing, and this is B component;
Step 3, preparation C component: getting standby after 10-20 grams of mix homogeneously of 3-8 grams of fibroblast growth factors and agar is C component;
Step 4, gets calcium alginate fibre non-woven fabrics or medical adhesive-bonded fabric standby, and this is D component;
Step 5, A component and B component are blended in the blender of high shear and stir, its rotating speed is 3000-3500 to turn, mixing time is 10-25 minutes, make its abundant mix homogeneously, become semigel state, after slowly add C component to stir, mixing speed should slow down and turn for Revolution Per Minute 150-200, mixing time is 30-45 minutes, by A component, the mixed material of B component and C component is placed standby on one side, get 10 square metres of D components, put into two roller extrusion coating machines, again by standby A component, it is to be coated with fabric sterile honey dressing below 10 degree or 10 are spent in temperature that B component and the mixed material of C component add in two roller extrusion coating machines, the A component of its every square metre D component coating, B component and the mixed material of C component are 200-350 grams.
In step 1 of the present invention, the weight of UMF accounts for 8% of Manuka honey gross weight, and the weight of adding pure water in Manuka honey is 20 grams.In step 2 of the present invention, the weight of cross-linked carboxymethyl fiber sodium is that 70 grams, the weight of sodium carboxymethyl cellulose are 120 grams.In step 3 of the present invention, fibroblast growth factor is 5 grams, 15 grams, agar.Rotating speed when A component and B component stir in step 5 of the present invention is 3000 to turn, the time of stirring is 15 minutes, adding C component mixing speed to slow down turns for Revolution Per Minute 150, mixing time is 30 minutes, and A component, B component and the mixed material of C component of every square metre of D component coating are 200 grams.
The present invention has following beneficial effect: Manuka honey is the flower that adopt the free of contamination purlieu growth in Zelanian coastal area a kind of makes the black tea of Manuka (manuka) set, the nectar being gathered by local Apis, this nectar is distinctive Manuka honey, in this Manuka honey, contain a kind of distinctive active antibacterial material---manuka factor UMF(Unigue.Manuka Factor), the present invention is the medical dressing that adopts a kind of Manuka sterilization Mel and calcium alginate non-woven fabrics or medical adhesive-bonded fabric made, make like this dressing have stronger sterilizing ability and provide oligosaccharide nutrition to enhance metabolism, accelerate the healing of wound, thereby not only can absorb a large amount of wound fluids, the enough nutrition of wound is provided, can clear up the harmful substance of wound, and provide the fibroblast production factor of wound, promote wound healing, enough active substances that can sterilize are provided, provide the wet environment of wound, it is not formed a scab, deliberately reduce the formation of cicatrix.Manuka honey has unique anti-microbial property and oxidation resistance, have more the ability of superpower destruction antibacterial, and can better treat the wound of body, it is a kind of medicine of natural treatment wound, without any side effect, " superfine product in honey " in Mel, being equipped with crosslinked cross-linked carboxymethyl fiber sodium and cross-linked carboxymethyl fiber sodium can increase the processing of wound and hygroscopic effect, being equipped with fibroblast growth factor and agar can accelerating wound, in sum, the present invention has the following advantages: Manuka honey can provide enough antimicrobial components; 2, Manuka honey only needs seldom composition just can have the effect of sterilization; 3, the antibacterial activity of Manuka honey equals the silver-colored sterilizing ability of 15000ppm.The operation below 10 degree Celsius of all temperature is produced above, in order to avoid too high and make Manuka honey produce rheological phenomena and affect the uniformity of coating and fibroblast growth factor and lose activity because of excess Temperature.Above manufactured goods are cut into needed specification and be applied to wound.It is 10 degree or coating below 10 degree in temperature that A component of the present invention, B component and the mixed material of C component add in two roller extrusion coating machines, like this in order to avoid too high and make Manuka honey generation rheological phenomena and affect the uniformity of coating and fibroblast growth factor and lose activity because of excess Temperature.
The specific embodiment
The preparation method that the invention discloses a kind of sterile honey dressing, it comprises the following steps:
Step 1, preparation A component: get 1000 grams of Manuka honeys, in Manuka honey, contain antimicrobial component UMF, the weight of UMF accounts for 8% of Manuka honey gross weight, adds 20 grams of pure water and through the mixing for standby use that stirs, be prepared into A component again in Manuka honey, step 2, preparation B component: the weight of getting cross-linked carboxymethyl fiber sodium is that 70 grams, the weight of sodium carboxymethyl cellulose are standby after 120 grams of mixing, and this is B component, step 3, preparation C component: getting standby after 15 grams of mix homogeneously of 5 grams of fibroblast growth factors and agar is C component, step 4, gets calcium alginate fibre non-woven fabrics or medical adhesive-bonded fabric standby, and this is D component, step 5, A component and B component are blended in the blender of high shear and stir, its rotating speed is 3000 to turn, mixing time is 10 minutes, make its abundant mix homogeneously, become semigel state, after slowly add C component to stir, mixing speed should slow down and turn for Revolution Per Minute 150, mixing time is 30 minutes, by A component, the mixed material of B component and C component is placed standby on one side, get 10 square metres of D components, put into two roller extrusion coating machines, again by standby A component, it is to be coated with fabric sterile honey dressing below 10 degree or 10 are spent in temperature that B component and the mixed material of C component add in two roller extrusion coating machines, the A component of its every square metre D component coating, B component and the mixed material of C component are 200 grams.
Claims (5)
1. a preparation method for sterile honey dressing, it comprises the following steps:
Step 1, preparation A component: get 1000 grams of Manuka honeys, in Manuka honey, contain antimicrobial component UMF, the weight of UMF accounts for 6-10% of Manuka honey gross weight, adds 10-25 grams of pure water and through the mixing for standby use that stirs, be prepared into A component again in Manuka honey;
Step 2, preparation B component: the weight of getting cross-linked carboxymethyl fiber sodium is that 50-100 grams, the weight of sodium carboxymethyl cellulose are standby after 100-150 grams of mixing, and this is B component;
Step 3, preparation C component: getting standby after 10-20 grams of mix homogeneously of 3-8 grams of fibroblast growth factors and agar is C component;
Step 4, gets medical adhesive-bonded fabric standby, and this is D component;
Step 5, A component and B component are blended in the blender of high shear and stir, its rotating speed is 3000-3500 to turn, mixing time is 10-25 minutes, make its abundant mix homogeneously, become semigel state, after slowly add C component to stir, mixing speed should slow down and turn for Revolution Per Minute 150-200, mixing time is 30-45 minutes, by A component, the mixed material of B component and C component is placed standby on one side, get 10 square metres of D components, put into two roller extrusion coating machines, again by standby A component, it is that below 10 degree, coating makes sterile honey dressing in temperature that B component and the mixed material of C component add in two roller extrusion coating machines, the A component of its every square metre D component coating, B component and the mixed material of C component are 200-350 grams.
2. the preparation method of sterile honey dressing according to claim 1, is characterized in that in step 1, the weight of UMF accounts for 8% of Manuka honey gross weight, and the weight of adding pure water in Manuka honey is 20 grams.
3. the preparation method of sterile honey dressing according to claim 1, the weight that it is characterized in that cross-linked carboxymethyl fiber sodium in step 2 is that 70 grams, the weight of sodium carboxymethyl cellulose are 120 grams.
4. the preparation method of sterile honey dressing according to claim 1, is characterized in that in step 3, fibroblast growth factor is 5 grams, 15 grams, agar.
5. the preparation method of sterile honey dressing according to claim 1, it is characterized in that rotating speed when A component and B component stir in step 5 is 3000 to turn, the time of stirring is 15 minutes, adding C component mixing speed to slow down turns for Revolution Per Minute 150, mixing time is 30 minutes, and A component, B component and the mixed material of C component of every square metre of D component coating are 200 grams.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110393076.1A CN102406958B (en) | 2011-12-02 | 2011-12-02 | Preparation method of sterile honey dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110393076.1A CN102406958B (en) | 2011-12-02 | 2011-12-02 | Preparation method of sterile honey dressing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102406958A CN102406958A (en) | 2012-04-11 |
| CN102406958B true CN102406958B (en) | 2014-04-09 |
Family
ID=45909490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110393076.1A Active CN102406958B (en) | 2011-12-02 | 2011-12-02 | Preparation method of sterile honey dressing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102406958B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272259A (en) * | 2013-06-16 | 2013-09-04 | 褚加冕 | Preparation method of medical honey dressing |
| CN105288709B (en) * | 2015-11-05 | 2018-05-22 | 上海典范医疗科技有限公司 | wet wound dressing and preparation method thereof |
| CN107468674A (en) * | 2017-09-18 | 2017-12-15 | 泰州市榕兴医疗用品股份有限公司 | Honey sterilization bandage and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1409636A (en) * | 1999-12-09 | 2003-04-09 | 威凯托陵科有限公司 | Use of honey in medical dressings |
| CN1444488A (en) * | 2000-06-30 | 2003-09-24 | 菲利普·罗伊·卡斯基 | Use and improvement of honey in wound dressings |
| CN102083473A (en) * | 2008-06-06 | 2011-06-01 | 马卢卡医学有限公司 | Compositions comprising honey and a super-absorbent material |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2382527A (en) * | 2001-12-03 | 2003-06-04 | Acordis Speciality Fibres Ltd | Wound dressings |
| WO2005077402A1 (en) * | 2004-02-11 | 2005-08-25 | Virchow Biotech Private Limited | Honey based gel formulations |
| JP2009541016A (en) * | 2006-06-23 | 2009-11-26 | ジェンテック インコーポレイテッド | Ultrathin wound dressing provided with a release sheet having a bent portion |
-
2011
- 2011-12-02 CN CN201110393076.1A patent/CN102406958B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1409636A (en) * | 1999-12-09 | 2003-04-09 | 威凯托陵科有限公司 | Use of honey in medical dressings |
| CN1444488A (en) * | 2000-06-30 | 2003-09-24 | 菲利普·罗伊·卡斯基 | Use and improvement of honey in wound dressings |
| CN102083473A (en) * | 2008-06-06 | 2011-06-01 | 马卢卡医学有限公司 | Compositions comprising honey and a super-absorbent material |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102406958A (en) | 2012-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104758977B (en) | A kind of alginate dressing for treating bedsore and preparation method thereof | |
| EP2842580B1 (en) | Silvery antibacterial fibre, texture, and wound dressing, and preparation method thereof | |
| CN104248776B (en) | For the preparation method of the antiseptic solution of dressing, antiseptic dressing and antiseptic dressing | |
| CN103212106B (en) | Method for preparing bacterial cellulose slow-release analgesia dressing | |
| CN102406958B (en) | Preparation method of sterile honey dressing | |
| CN104524624A (en) | Chitosan hemostatic gauze and preparation method thereof | |
| CN110237295A (en) | A kind of anthocyanidin alginate dressing | |
| CN101886338A (en) | Biological antibiotic cotton fibers or cotton cloth and method for preparing same | |
| CN101569761A (en) | Preparation method for medical honey dressing | |
| CN103083712A (en) | Stem cells or other bioactive substances doped surgical dressing | |
| CN104436286A (en) | Pectin hemostatic gauze and preparation method thereof | |
| CN103638551A (en) | Preparation method for chitosan 6-OH immobilized cyclodextrin included tea tree oil thermo-sensitive hydrogel | |
| CN104587519A (en) | Dressing containing traditional Chinese medicine | |
| CN108018620A (en) | Antibiotic property sodium zirconium phosphate silver alginate fibre and preparation method thereof | |
| CN107033397A (en) | A kind of preparation method of calcium chelant carboxyl chitosan/organo montmorillonite gel rubber material | |
| CN203315406U (en) | PEG (polyethylene glycol) hydrogel structure | |
| CN101732758A (en) | Preparation method of biological calcium alginate antiseptic dressing | |
| CN101732757A (en) | Method for preparing biological calcium alginate antimicrobial dressing | |
| CN103272133A (en) | Preparation method of fermented substance for diminishing inflammation and stopping bleeding | |
| CN104474579A (en) | Hydroxypropyl-beta-cyclodextrin hemostatic gauze and preparation method thereof | |
| CN104491919A (en) | Propolis hemostatic gauze and preparation method thereof | |
| CN107998435A (en) | A kind of polyvinyl alcohol/chitosan oligosaccharide/silver composite fibre dressing and preparation method thereof | |
| CN107956036B (en) | Support the 3D screen cloth of Pneumatic soles | |
| CN102133423A (en) | Petrolatum gauze resisting bacteria and diminishing inflammation and production process thereof | |
| CN102058898B (en) | Powder with antibacterial and haemostatic effects and preparation method and applications thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TAIZHOU RONGXING ANTI-ADHESION DRESSING CO., LTD. Free format text: FORMER OWNER: CHU JIAMIAN Effective date: 20150327 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 225321 TAIZHOU, JIANGSU PROVINCE TO: 225300 TAIZHOU, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20150327 Address after: 225300, No. 8, Far East Avenue, Taizhou high port area, Jiangsu Patentee after: Taizhou Rongxing Anti-adhesion Dressing Co., Ltd. Address before: 225321 Taizhou, Jiangsu Port Industrial Park, Far East Avenue, No. 8 Patentee before: Chu Jiamian |
|
| C56 | Change in the name or address of the patentee | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 225300, No. 8, Far East Avenue, Taizhou high port area, Jiangsu Patentee after: ROOSIN MEDICAL CO., LTD. Address before: 225300, No. 8, Far East Avenue, Taizhou high port area, Jiangsu Patentee before: Taizhou Rongxing Anti-adhesion Dressing Co., Ltd. |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of sterilized honey dressing Effective date of registration: 20201215 Granted publication date: 20140409 Pledgee: Bank of China Limited by Share Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT Co.,Ltd. Registration number: Y2020980009396 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20211228 Granted publication date: 20140409 Pledgee: Bank of China Limited by Share Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT CO.,LTD. Registration number: Y2020980009396 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of bactericidal honey dressing Effective date of registration: 20211229 Granted publication date: 20140409 Pledgee: Bank of China Limited by Share Ltd. Taizhou Gaogang sub branch Pledgor: TAIZHOU ROOSIN MEDICAL PRODUCT CO.,LTD. Registration number: Y2021980016869 |