CN102380087A - Chinese medicinal composition for treating cough and dyspnea - Google Patents

Chinese medicinal composition for treating cough and dyspnea Download PDF

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Publication number
CN102380087A
CN102380087A CN2011104220632A CN201110422063A CN102380087A CN 102380087 A CN102380087 A CN 102380087A CN 2011104220632 A CN2011104220632 A CN 2011104220632A CN 201110422063 A CN201110422063 A CN 201110422063A CN 102380087 A CN102380087 A CN 102380087A
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parts
chinese medicine
asthma
cough
fructus
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CN2011104220632A
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张仙峰
张晓茹
张晓东
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Xian Fuan Creative Consulting Co Ltd
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Xian Fuan Creative Consulting Co Ltd
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Abstract

The invention relates to an oral Chinese medicinal preparation, in particular to a Chinese medicinal composition for treating cough and dyspnea. The Chinese medicinal composition is characterized by being prepared form the following Chinese medicinal bulk pharmaceuticals in parts by weight: 50-100 parts of loguat leaf, 50-100 parts of birthwort, 15-30 parts of liquoric root, 15-50 parts of platycodon root, 30-100 parts of common coltsfoot flower, 10-30 parts of apricot kernel, 10-30 parts of Chinese magnoliavine fruit, 10-30 parts of dried orange peel, 10-20 parts of divaricate saposhnikovia root, 30-100 parts of bamboo juice, 50-80 parts of ginger juice and 20-80 parts of coix seed. The Chinese medicinal composition has the effects of clearing and lowering lung heat, reducing phlegm, relieving cough and relieving asthma, has a remarkable effect and a small side effect after being taken.

Description

A kind of Chinese medicine composition of treating cough with asthma
Technical field
The present invention relates to a kind of oral Chinese medicine preparation, particularly a kind of Chinese medicine composition of treating cough with asthma.
Background technology
Cough with asthma is the cardinal symptom of pneumonopathy.The cause of disease of cough with asthma has the diseases caused by exogenous pathogenic factor internal injury not, and pathogenesis has the branch of cold and heat and asthenia and sthenia.Ancients think: sound no expectorant is for coughing, and noiseless have expectorant for coughing.The generation of this disease is mainly due to disturbance of lung-QI due to the superinverse.Cough illness is prone to outbreak repeatedly, is difficult to speed more.The western medical treatment cough with asthma mainly depends on hormone and antibiotics, and life-time service can cause the generation of diseases such as hypertension.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of treating cough with asthma and preparation method thereof, it has and falls lung-heat clearly, the effect of expectorant cough suppressant and anti-asthmatic, and it is remarkable to take the back effect, and side effect is little.
Technical scheme of the present invention is: a kind of Chinese medicine composition of treating cough with asthma is characterized in that: the raw material of Chinese medicine medicine by following weight parts is formulated: Folium Eriobotryae 50-100 part, Fructus Aristolochiae 50-100 part, Radix Glycyrrhizae 15-30 part, Radix Platycodonis 15-50 part, Flos Farfarae 30-100 part, Semen Armeniacae Amarum 10-30 part, Fructus Schisandrae Chinensis 10-30 part, Pericarpium Citri Reticulatae 10-30 part, windproof 10-20 part, Succus Bambusae 30-100 part, Sucus Zingberis 50-80 part, Semen Coicis 20-80 part.
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 80 parts of Folium Eriobotryaes, 80 parts of Fructus Aristolochiaes, 20 parts in Radix Glycyrrhizae, 30 parts of Radix Platycodoniss, 70 parts of Flos Farfaraees, 20 parts in Semen Armeniacae Amarum, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Pericarpium Citri Reticulataes, windproof 15 parts, 60 parts of Succus Bambusaes, 60 parts of Sucus Zingberis, 50 parts of Semen Coiciss.
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 50 parts of Folium Eriobotryaes, 50 parts of Fructus Aristolochiaes, 15 parts in Radix Glycyrrhizae, 15 parts of Radix Platycodoniss, Flos Farfarae 30-100 part, 10 parts in Semen Armeniacae Amarum, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Pericarpium Citri Reticulataes, windproof 10 parts, 30 parts of Succus Bambusaes, 50 parts of Sucus Zingberis, 20 parts of Semen Coiciss.
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 100 parts of Folium Eriobotryaes, 100 parts of Fructus Aristolochiaes, 30 parts in Radix Glycyrrhizae, 50 parts of Radix Platycodoniss, 100 parts of Flos Farfaraees, 30 parts in Semen Armeniacae Amarum, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Pericarpium Citri Reticulataes, windproof 20 parts, 100 parts of Succus Bambusaes, 80 parts of Sucus Zingberis, 80 parts of Semen Coiciss.
The present invention also provides the method for preparing of above-mentioned Chinese medicine composition, comprises the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), with in the Semen Armeniacae Amarum encroached water, the peeling, subsequent use;
3), the above-mentioned raw materials medicine is mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
4), with step 2) medicinal residues that the obtain decocting that adds 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
5), with step 2), 3) filtrating, Succus Bambusae and the Sucus Zingberis that obtain mix and be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
6), thick paste that step 4) is obtained is dry, is ground into fine powder, processes capsule.
Characteristics of the present invention are reasonable recipe, meet theory of Chinese medical science: Folium Eriobotryae bitter in the mouth, clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI; The Fructus Aristolochiae bitter in the mouth, lung heat clearing sending down the abnormal ascending QI, relieving cough and asthma, the bowel relieving hemorrhoid that disappear; The Radix Glycyrrhizae sweet in the mouth, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain; Radix Platycodonis is arduous, lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus; The hot temperature of Flos Farfarae, nourishing the lung to keep the adverse QI downward, antitussive reduces phlegm; Semen Armeniacae Amarum has expelling phlegm for arresting cough; Relieving asthma; The effect of intestine moistening; Fructus Schisandrae Chinensis is warm in nature, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; Pericarpium Citri Reticulatae is arduous, regulating qi-flowing for strengthening spleen, and in the accent, dampness is reduced phlegm; Windproof sweet in the mouth, expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion; Succus Bambusae sweetness and bitterness, the sliding expectorant of heat clearing away, relieving convulsion sharp key; Sucus Zingberis is warm in nature, and cold expelling is arranged, the effect of preventing or arresting vomiting; The Semen Coicis sweet in the mouth, spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal; The mixing of above-mentioned raw materials medicine has falls lung-heat clearly, the effect of expectorant cough suppressant and anti-asthmatic.
The specific embodiment
Through the specific embodiment that provides the present invention is described clearly further below, but not as to qualification of the present invention.
Embodiment 1
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 80 parts of Folium Eriobotryaes, 80 parts of Fructus Aristolochiaes, 20 parts in Radix Glycyrrhizae, 30 parts of Radix Platycodoniss, 70 parts of Flos Farfaraees, 20 parts in Semen Armeniacae Amarum, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Pericarpium Citri Reticulataes, windproof 15 parts, 60 parts of Succus Bambusaes, 60 parts of Sucus Zingberis, 50 parts of Semen Coiciss.The present invention also provides the method for preparing of above-mentioned Chinese medicine composition, comprises the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), with in the Semen Armeniacae Amarum encroached water, the peeling, subsequent use;
3), the above-mentioned raw materials medicine is mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
4), with step 2) medicinal residues that the obtain decocting that adds 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
5), with step 2), 3) filtrating, Succus Bambusae and the Sucus Zingberis that obtain mix and be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
6), thick paste that step 4) is obtained is dry, is ground into fine powder, processes capsule.
Embodiment 2
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 50 parts of Folium Eriobotryaes, 50 parts of Fructus Aristolochiaes, 15 parts in Radix Glycyrrhizae, 15 parts of Radix Platycodoniss, Flos Farfarae 30-100 part, 10 parts in Semen Armeniacae Amarum, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Pericarpium Citri Reticulataes, windproof 10 parts, 30 parts of Succus Bambusaes, 50 parts of Sucus Zingberis, 20 parts of Semen Coiciss.Preparation and method for using are with embodiment 1.
Embodiment 3
Said a kind of weight portion of treating the Chinese medicine composition of cough with asthma is: 100 parts of Folium Eriobotryaes, 100 parts of Fructus Aristolochiaes, 30 parts in Radix Glycyrrhizae, 50 parts of Radix Platycodoniss, 100 parts of Flos Farfaraees, 30 parts in Semen Armeniacae Amarum, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Pericarpium Citri Reticulataes, windproof 20 parts, 100 parts of Succus Bambusaes, 80 parts of Sucus Zingberis, 80 parts of Semen Coiciss.
Preparation and method for using are with embodiment 1.
The umber of Chinese medicine component can be got gram (g), kilogram (kg), ton (t).
Main pharmacodynamics test is following:
Zoopery
60 mices are divided into 5 groups by body weight, sex equilibrium; Every group 10, blank group (giving 5%CMC-Na), embodiment group (embodiment 1 (100mg/kg), embodiment 2 (50mg/kg), embodiment 3 (200mg/kg)) KECHUANWANG group (200mg/kg), each treated animal is irritated to relative medicine every day; Continuous 7 days; Half an hour after the last administration, with mice as in the inverted 500ml beaker, the number of times of observing and coughing in incubation period and 5 minutes that the record mice coughs.
It is as shown in the table for experimental result: the therapeutic effect that the result shows 1,2,3 groups of embodiment and matched group specific energy mutually obviously prolong the number of times of coughing in the incubation period and 5 minutes that mice coughs.
Figure 333623DEST_PATH_IMAGE001
In order to show the therapeutic effect of medicine of the present invention, the present invention has carried out clinical trial.
The clinical trial of a kind of Chinese medicine composition of treating cough with asthma proposed by the invention is following: select age 40-60 year patient 40 examples, 50 years old mean age, the course of disease 1 year-3 years, average course of disease 2 years.The patient did not accept other treatment before this treatment.30 days is a course of treatment, carries out symptom score after 20 days.160 routine patients are divided into 4 groups at random, every group 10 example, and treatment group 1 adopts medicine of the present invention; Material component and treatment group 1 that treatment group 2 adopts are the same materials components, and production technology is different, and treatment group 2 is that all material components separately are brewed into paste medicine; Contrast A group is regularly taken Western medicine virus file; Contrast B group is loose with compound recipe crown prince cough-relieving QI invigorating; Be careful in one's diet during this time and have a rest.
Therapeutic outcome:
Treat after 20 days, therapeutic effect is relatively seen table 1.
Table 1 pharmaceutical treatment of the present invention is the effect comparison after 20 days
Group Number Produce effects Take a turn for the better Invalid 28 days effective percentage
Treatment group 1 40 20 10 10 75%
Treatment group 2 40 18 8 14 65%
Contrast A group 40 17 7 16 60%
Contrast B group 40 18 6 16 60%
Visible by table 1; The effect of treatment group 1 of using the made Chinese medicine of the present invention is apparently higher than treatment group 2 (P < 0.05); Explain that production technology has very big influence to therapeutic effect, the effect of treatment group 1 is apparently higher than contrast A group and contrast B group (P < 0.05), and symptom takes a turn for the better apparently higher than diffusing with Western medicine virus file and compound recipe crown prince cough-relieving QI invigorating; The therapeutic effect that shows the medicament that use the present invention is made is remarkable, and obvious effective rate is high.

Claims (5)

1. Chinese medicine composition of treating cough with asthma, it is characterized in that: the raw material of Chinese medicine medicine by following weight parts is formulated: Folium Eriobotryae 50-100 part, Fructus Aristolochiae 50-100 part, Radix Glycyrrhizae 15-30 part, Radix Platycodonis 15-50 part, Flos Farfarae 30-100 part, Semen Armeniacae Amarum 10-30 part, Fructus Schisandrae Chinensis 10-30 part, Pericarpium Citri Reticulatae 10-30 part, windproof 10-20 part, Succus Bambusae 30-100 part, Sucus Zingberis 50-80 part, Semen Coicis 20-80 part.
2. according to the said a kind of Chinese medicine composition of treating cough with asthma of claim 1, it is characterized in that: its weight portion is: 80 parts of Folium Eriobotryaes, 80 parts of Fructus Aristolochiaes, 20 parts in Radix Glycyrrhizae, 30 parts of Radix Platycodoniss, 70 parts of Flos Farfaraees, 20 parts in Semen Armeniacae Amarum, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Pericarpium Citri Reticulataes, windproof 15 parts, 60 parts of Succus Bambusaes, 60 parts of Sucus Zingberis, 50 parts of Semen Coiciss.
3. according to the said a kind of Chinese medicine composition of treating cough with asthma of claim 1, it is characterized in that: its weight portion is: 50 parts of Folium Eriobotryaes, 50 parts of Fructus Aristolochiaes, 15 parts in Radix Glycyrrhizae, 15 parts of Radix Platycodoniss, Flos Farfarae 30-100 part, 10 parts in Semen Armeniacae Amarum, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Pericarpium Citri Reticulataes, windproof 10 parts, 30 parts of Succus Bambusaes, 50 parts of Sucus Zingberis, 20 parts of Semen Coiciss.
4. according to the said a kind of Chinese medicine composition of treating cough with asthma of claim 1, it is characterized in that: its weight portion is: 100 parts of Folium Eriobotryaes, 100 parts of Fructus Aristolochiaes, 30 parts in Radix Glycyrrhizae, 50 parts of Radix Platycodoniss, 100 parts of Flos Farfaraees, 30 parts in Semen Armeniacae Amarum, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Pericarpium Citri Reticulataes, windproof 20 parts, 100 parts of Succus Bambusaes, 80 parts of Sucus Zingberis, 80 parts of Semen Coiciss.
According to claim 1-4 described a kind of treat cough with asthma the method for preparing of Chinese medicine composition, comprise the steps:
1) crude drug of getting in the above-mentioned raw materials carries out roguing respectively, and clean, dry, subsequent use;
2), with in the Semen Armeniacae Amarum encroached water, the peeling, subsequent use;
3), the above-mentioned raw materials medicine is mixed, and the decocting that adds 10 times of amounts boils, and decocts 2 hours after-filtration, filtrate for later use;
4), with step 2) medicinal residues that the obtain decocting that adds 8 times of amounts again boils 2 hours after-filtration, filtrate for later use;
5), with step 2), 3) filtrating, Succus Bambusae and the Sucus Zingberis that obtain mix and be incorporated in 60 ℃ and be evaporated to the thick paste that relative density is 1.20-1.25, and be subsequent use;
6), thick paste that step 4) is obtained is dry, is ground into fine powder, processes capsule.
CN2011104220632A 2010-12-16 2011-12-16 Chinese medicinal composition for treating cough and dyspnea Pending CN102380087A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550594A (en) * 2013-11-13 2014-02-05 张笑飞 Lung clearing traditional Chinese medicine for children
CN115381905A (en) * 2022-09-28 2022-11-25 江西李氏烤鲜竹沥药业有限公司 Bamboo juice ointment for clearing heat and reducing phlegm and preparation method thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106692504B (en) * 2016-12-29 2020-08-21 北京澳特舒尔保健品开发有限公司 Health food with effects of clearing heat from throat, relieving cough, moistening lung and preventing haze and preparation method of health food

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550594A (en) * 2013-11-13 2014-02-05 张笑飞 Lung clearing traditional Chinese medicine for children
CN103550594B (en) * 2013-11-13 2016-03-30 张笑飞 Child's lung heat clearing Chinese medicine
CN115381905A (en) * 2022-09-28 2022-11-25 江西李氏烤鲜竹沥药业有限公司 Bamboo juice ointment for clearing heat and reducing phlegm and preparation method thereof

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Application publication date: 20120321