CN102114206B - Powder capable of restoring function of pancreatic islet and preparation method thereof - Google Patents
Powder capable of restoring function of pancreatic islet and preparation method thereof Download PDFInfo
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Abstract
The invention relates to powder capable of restoring the function of the pancreatic islet and the preparation method thereof. The powder is made by adopting the following steps that mulberry fruit, Fructus Lycii, Fructus Citri Sarcodactylis, Poria, pumpkin, Semen Coicis, Radix Puerariae, Fructus Citri, Radix Ginseng and Radix Astragali are weighed according to the parts by weight; the above component materials are mixed and decocted in water twice, wherein 10 weight times of water is added for the first time and the decoction time is 2 hours, and 8 weight times of water is added for the second time and the decoction time is 1.5 hours; the solution extracted from twice decoctions is filtered through a 160 to 180 mesh sieve respectively, and filtrate is concentrated until the density ranges from 1.23 g/cm3 to 1.26 g/cm3 to produce extract; the extract is vacuumized, pulverized and sieved through a 80 to 100 mesh sieve to produce fine powder; the fine powder is uniformly mixed with cooked millet powder and cooked sesame seed according to the weight fraction mixture ratio of 1:3 to 6:0.5 to 1, and the powder is obtained. By adopting the powder, nutrients can be supplied to the islet cells, the function of the pancreatic islet is improved, the glycemic indexes of foods can be effectively controlled, the fasting blood glucose level and the postprandial blood glucose level are lowered, the dosage of antidiabetic drugs is reduced, and the life quality is improved.
Description
Technical field
The present invention relates to a kind of powder and preparation method thereof, particularly relate to a kind of have can recover powder of islet function and preparation method thereof.
Background technology
Diabetes are a kind of whole body chronic metabolic disease that determined by gene.Its main feature is hyperglycemia.According to the suggestion of the World Health Organization (WHO) and expert group of IDF (IDF), diabetes can be divided into 4 kinds of I type, II type, other specific types and gestational diabetes.
Type Ⅰ diabetes mellitus prevalence is far below type Ⅱdiabetes mellitus.Because the disease symptom of child's type Ⅰ diabetes mellitus is generally comparatively obvious, not easy to cause missed diagnosis.
When type Ⅱdiabetes mellitus onset, symptom is more hidden, be difficult to obtain and make a definite diagnosis in the time of onset, but its prevalence is higher.In recent years, the prevalence of countries in the world type Ⅱdiabetes mellitus all has the trend sharply increasing, and the trend that in nearly 30 or five ten years, type Ⅱdiabetes mellitus sharply increases is still difficult to alleviate.Also there are a large amount of blood sugar increasing outward but do not reach diabetes diagnosis standard person.After their fasting glucose, after the meal 2 hours blood glucoses or clothes sugar, 2 hours blood glucoses are between euglycemia and diabetes diagnosis standard.Diabetes educational circles tends to this class to it is called as IGR (impaired glucose regulation, IGR) person's (vulnerable crowd) at present, and domestic have 1.48 hundred million at present.
Very " simply " of method for the treatment of diabetes at present: the first, since there is no insulin or insufficient insulin in type Ⅰ diabetes mellitus blood, that is with regard to hormone insulin.Such result is that pancreatic function is replaced, has finally lost the function of excreting insulin.Second, in type Ⅱdiabetes mellitus blood, blood sugar level is high, just take antidiabetic drug, mainly contain sulphanylureas, biguanides, alpha-glucosidase inhibitor, thiazolidinediones and non-sulphanylureas insulin succagoga etc., the curative effect of these chemicalses is clear and definite, but limitation and untoward reaction exist equally, as: prolonged application insulin easily produces insulin resistant, and sulphanylureas causes that hypoglycemia, biguanides cause that lactic acidosis, α glycosidase inhibitor cause gastrointestinal side effect etc.Be blocking-up or the sugar that the slows down speed that enters blood outwardly, to be blood glucose level drops in blood get off the result of detection, but cannot solve root problem.Take antidiabetic drug, dosage is larger, and toxicity is also larger, involves Liver and kidney; Between antidiabetic drug action period, cell can not get nutrition, and cell viability goes down, and resists the ability of disease and accelerates to decline, and therefore complication rises.And the compliance aspect of Chinese medicine, natural drug long-term prescription shows certain advantage, particularly in recent years, from Chinese medicine, screening has the medicine of hypoglycemic activity and compound preparation research work progress rapidly, study hotspot and exploitation direction are become, but treat merely the method for diabetes taking blood sugar lowering as object, more and more can not reach the object for the treatment of, should not continue promotion and application.The 3rd, auxiliary treatment: motion, diet, to have a rest and change lifestyles be correct, just should be towards this direction effort, but is not enough to the diabetes that treatment has formed.Especially existing diet auxiliary treatment, patient adopts diet control therapy for a long time, dare not eat, cause endotrophic composition picked-up imbalance, nutritional disorder, body constitution to decline, cause the appearance of various complication, bring a new difficult problem to again the treatment of diabetes and the control of complication, also become a difficult problem for global treatment diabetes simultaneously.The problem of diabetes is not because blood glucose height in blood in fact, neither lack because of insulin in blood, but because the defunctionalization of pancreas or reduced because the vigor of cell has declined, what show is that insulin is few, and blood sugar level has raise.The way of existing treatment diabetes: insulin injection and take antidiabetic drug for insulin disappearance and high these format surfaces of blood glucose, and the most basic pancreatic function and cell viability are taken measures.Correct direction is to recover the normal function of pancreas and cell, recovers the instinct of human body and natural capacity of self-regulation.
Traditional diabetic diet control therapy, generally adopt and do not eat sugary food, sugarfree foods on market adopts the method for not sugaring or adds the sweeting agents such as not sugary xylitol, increases merely the mouthfeel of sweet taste, causes diabetics saccharide source disappearance.
As everyone knows, sugar is one of indispensable important nutrient of human body, carry out mechanical control blood glucose with the absorption of not absorbing sugar or few picked-up sugar or rely on medicine to reduce sugar and reach so-called criterion of acceptability, just think and well controlled diabetes, this is very large mistaken ideas.Many dieletic foodstuffs on market, the overwhelming majority develops under this theory, even some is mixed the genuine with the fictitious, more seriously, the unscientific publicity of many sugarfree foods producer, causes unnecessary the seeing of patient " sugar " fear, cause the reduction of patient's index number of price, body constitution to decline, resistance reduces, and diabetes continue development, and cause serious complication.Bring larger misery to patient, for treatment from now on has also brought very large difficulty.
Summary of the invention
object of the present inventionbeing to provide one can nourishing pancreas islet cell, improves islet function, effectively controls the sugared index of life of food, reduces on an empty stomach and post-prandial glycemia, reduces the consumption for the treatment of diabetes medicament, and that improves the quality of living has a powder that can recover islet function.
Another object of the present invention is to provide a kind of preparation method with the powder that can recover islet function.
the present invention adopts following technical scheme:
A kind of have a powder that can recover islet function, it is characterized in that adopting following method to make: the first step: take by weight: 12～15 parts, Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts, Poria, 12～14 parts, Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder.
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weight: 12～15 parts, Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts, Poria, 12～14 parts, Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder.
beneficial effect of the present inventionbe: patient can add powder of the present invention the hot water of 3～5 times according to every 50g this product, directly edible after stirring.Every day edible this product 50～100g.
Powder treatment diabetes of the present invention have following features:
1, safety: product of the present invention is selected not only edible but also natural plants that can be medicinal, has no side effect, environmental protection.
2, convenient: use product of the present invention, patient is easy to use and carry.
3, evident in efficacy: use product of the present invention, can make general patient's glycemic control steady, nourishing pancreas islet cell, improves islet function.
In medicine powder formula of the present invention, the effect of each crude drug is:
fructus Citri Sarcodactylis:pungent, hardship, sweet, temperature, nontoxic, enter liver, spleen, stomach three warps, there are the multiple medicinal functions such as activating QI to eliminate phlegm, cough-relieving relieving distension, the liver soothing and the spleen invigorating stomach function regulating.
fructus Lycii:nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.Modern pharmacological research proves that Fructus Lycii extract can significantly and lastingly reduce rat blood sugar, increases carbohydrate tolerance.
fructus Mori:sweet in the mouth acid, cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving.There is the YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, the effect such as intestine moistening is dry.
radix Puerariae: sweet in the mouth, pungent, cool.Return spleen, stomach, lung meridian.There is expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, effect of alcoholic intoxication.
semen Coicis: sweet in the mouth is light, cool.Return spleen, stomach, lung meridian.There is promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, effect of detoxicating and resolving stagnation of pathogens.
fructus Citri: acrid in the mouth, hardship, acid, temperature.Return liver, spleen, lung meridian.There is depressed liver-energy dispersing and QI regulating, alleviating distention in middle-JIAO, clears phlegm.
poria: sweet in the mouth is light, flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.
fructus Cucurbitae moschatae:carry according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": Fructus Cucurbitae moschatae is warm in nature, and sweet in the mouth is nontoxic, enters spleen, stomach two warps, energy moistening lung qi-benefitting, the row of reducing phlegm is dense, and anthelmintic removing toxic substances, controls and coughs Zhichuan, treats lung abscess and constipation, and has the effect such as diuresis, beauty treatment.Squash polyoses is a kind of nonspecific immunity strengthening agent, can improve the immunologic function of body, promotes cytokine to generate, and by approach such as complement activations, immune system is brought into play to many-sided regulatory function.
radix Ginseng:sweet in the mouth, micro-hardship, flat; Return spleen, lung, heart channel.Have strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, effect of promoting the production of body fluid and inducing sedation of the mind.
the Radix Astragali:sweet in the mouth, temperature; Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.
Adopt the present invention to recover islet function clinical treatment standard as follows:
Eat powder of the present invention 1-2 times every day, and each 20-50 grams 8 weeks is a course for the treatment of;
Effective standard is: use 1 course for the treatment of of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) disappears, fasting glucose≤7.0mmol/L, or blood glucose is treated front decline >=30%, glycolated hemoglobin < 6.5%.
Effectively standard is: use 1 course for the treatment of of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) obviously changes, and fasting glucose≤8.3mmol/L or blood glucose are treated front decline >=10%, glycolated hemoglobin 6.5～7.5%.
Invalid standard is: use 1 course for the treatment of of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) is not improved, and blood glucose declines and do not reach above-mentioned standard, glycolated hemoglobin >=7.5%.
Patient's 314 examples that are put to the test, are diagnosed as type Ⅱdiabetes mellitus through hospital above county level, without severe cardiac Liver and kidney complication, and 27～70 years old age, to take continuously 56 days, experimental group is totally 314 examples, effective 90 examples, effective percentage 28.6%; Effective 156 examples, obvious effective rate 49.7%; Invalid 68 examples, inefficiency 21.6%, total effective rate 78.3%.
Model case:
Lee × ×, female, 48 years old, diabetic history 2 years, is used after powder of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 7.0mmol/L by 11.5mmol/L, and 2 hours blood glucoses are down to 10.0mmol/L by 19.2mmol/L, and taking this product, after 8 weeks, to look into glycolated hemoglobin be 6.0%.
Virgin × ×, man, 53 years old, diabetic history 3 years, is used after powder of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.8mmol/L by 12.6mmol/L, and 2 hours blood glucoses are down to 10.2mmol/L by 19.0mmol/L, and taking this product, after 8 weeks, to look into glycolated hemoglobin be 6.2%.
× ×, man, 56 years old, diabetic history 4 years, is used after powder of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.9mmol/L by 13.4mmol/L, and 2 hours blood glucoses are down to 10.1mmol/L by 20.2mmol/L, and taking this product, after 8 weeks, to look into glycolated hemoglobin be 6.3%.
Liu × ×, man, 51 years old, diabetic history 2 years, is used after powder of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.3mmol/L by 11.4mmol/L, and 2 hours blood glucoses are down to 10.6mmol/L by 18.2mmol/L, and taking this product, after 8 weeks, to look into glycolated hemoglobin be 5.9%.
Detailed description of the invention
Embodiment 1
There is the powder that can recover islet function, it is characterized in that adopting following method to make: the first step: take by weight: 12 parts, Fructus Mori, 18 parts of Fructus Lycii, 23 parts of Fructus Citri Sarcodactylis, 15 parts, Poria, 14 parts, Fructus Cucurbitae moschatae, 10 parts of Semen Coiciss, 11 parts of Radix Puerariaes, 16 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.23g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3:1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 80 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3:1, are obtained to described powder.
Embodiment 2
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weight: 15 parts, Fructus Mori, 16 parts of Fructus Lycii, 20 parts of Fructus Citri Sarcodactylis, 17 parts, Poria, 13 parts, Fructus Cucurbitae moschatae, 11 parts of Semen Coiciss, 12 parts of Radix Puerariaes, 15 parts of Fructus Citris, 7 parts of Radix Ginsengs, 10 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:4:0.5, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:4:0.5, are obtained to described powder.
Embodiment 3
There is the powder that can recover islet function, it is characterized in that adopting following method to make: the first step: take by weight: 13 parts, Fructus Mori, 15 parts of Fructus Lycii, 25 parts of Fructus Citri Sarcodactylis, 16 parts, Poria, 12 parts, Fructus Cucurbitae moschatae, 13 parts of Semen Coiciss, 10 parts of Radix Puerariaes, 18 parts of Fructus Citris, 6 parts of Radix Ginsengs, 11 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.24g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:6:0.8, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.24g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:6:0.8, are obtained to described powder.
Embodiment 4
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weight: 14 parts, Fructus Mori, 15 parts of Fructus Lycii, 22 parts of Fructus Citri Sarcodactylis, 17 parts, Poria, 12 parts, Fructus Cucurbitae moschatae, 13 parts of Semen Coiciss, 12 parts of Radix Puerariaes, 17 parts of Fructus Citris, 6 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:5:1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:5:1, are obtained to described powder.
Embodiment 5
There is the powder that can recover islet function, it is characterized in that adopting following method to make: the first step: take by weight: 15 parts, Fructus Mori, 18 parts of Fructus Lycii, 25 parts of Fructus Citri Sarcodactylis, 15 parts, Poria, 14 parts, Fructus Cucurbitae moschatae, 10 parts of Semen Coiciss, 11 parts of Radix Puerariaes, 16 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.25g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3:0.5, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.25g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 80 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3:0.5, are obtained to described powder.
Embodiment 6
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weight: 12 parts, Fructus Mori, 18 parts of Fructus Lycii, 20 parts of Fructus Citri Sarcodactylis, 17 parts, Poria, 14 parts, Fructus Cucurbitae moschatae, 12 parts of Semen Coiciss, 10 parts of Radix Puerariaes, 18 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:4:0.7, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm
3, obtain extractum, by gained extractum through vacuum drying,, pulverized 100 mesh sieves and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:4:0.7, are obtained to described powder.
Claims (2)
1. one kind has the powder that can recover islet function, it is characterized in that adopting following method to make: the first step: take by weight: 12～15 parts, Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts, Poria, 12～14 parts, Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder.
2. one kind has the preparation method of the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weight: 12～15 parts, Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts, Poria, 12～14 parts, Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtain extractum, gained extractum, through vacuum drying, was pulverized to 80-100 mesh sieve and obtained fine powder, fine powder and processed millet powder, Semen Sesami Nigrum, according to the ratio mix homogeneously of ratio of weight and number 1:3～6:0.5～1, are obtained to described powder.
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| CN201010618931.XA CN102114206B (en) | 2010-12-31 | 2010-12-31 | Powder capable of restoring function of pancreatic islet and preparation method thereof |
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| CN103055156A (en) * | 2012-12-28 | 2013-04-24 | 六安同济生生物科技有限公司 | Compound dendrobium huoshanense, cistanche and ganoderma extract and production process thereof |
| CN111838521A (en) * | 2020-03-16 | 2020-10-30 | 杨波 | Medicated diet functional flour assisting in reducing blood sugar, regulating lipid, losing weight and relieving insulin resistance |
| CN114431465A (en) * | 2022-01-24 | 2022-05-06 | 和也健康科技有限公司 | Blood glucose reducing RS3 composite brewing powder |
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Non-Patent Citations (4)
| Title |
|---|
| 屠庆祝等.浅谈中药治疗糖尿病的用药规律.《中医药临床杂志》.2005,第17卷(第3期),294-295. |
| 未知.[供应] 供应疏糖粉(疏糖粉).《食品产业网,网址:http://www.foodqs.cn/trades/tradepage/trade_view_1089459.html》.2007,1. * |
| 未知.【供应】 供应疏糖粉(疏糖粉).《食品产业网，网址：http://www.foodqs.cn/trades/tradepage/trade_view_1089459.html》.2007,1. |
| 浅谈中药治疗糖尿病的用药规律;屠庆祝等;《中医药临床杂志》;20050630;第17卷(第3期);294-295 * |
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