CN102113529B - Flour with function of treating diabetes and preparation method thereof - Google Patents

Flour with function of treating diabetes and preparation method thereof Download PDF

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CN102113529B
CN102113529B CN201010618937.7A CN201010618937A CN102113529B CN 102113529 B CN102113529 B CN 102113529B CN 201010618937 A CN201010618937 A CN 201010618937A CN 102113529 B CN102113529 B CN 102113529B
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王钢柱
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Abstract

The invention relates to flour with a function of treating diabetes and a preparation method thereof. The preparation method comprises the following steps of: 1, weighing the following components in part by weight: 10 to 13 parts of medlar, 12 to 15 parts of mulberry fruit, 20 to 25 parts of finger citron, 15 to 18 parts of cinnamomvine, 5 to 10 parts of common macrocarpium fruit, 5 to 10 parts of dwarf lilyturf tuber, 14 to 17 parts of siberian solomonseal rhizome and 10 to 12 parts of parslane herb; 2, mixing the components, adding water and decocting the mixture in water twice, wherein at the first time, water in an amount which is 10 times that of the mixture is added to decoct the mixture for 2 hours, and at the second time, the water in an amount which is 8 times that of the mixture is added to decoct the mixture for 1.5 hours; filtering decoction extract obtained at two times with a 160 to 180-mesh sieve, and concentrating filter liquor until the density is between 1.23 and 1.26 g/cm<3> to obtain extractum; drying the extractum under vacuum, crushing, and sieving with an 80 to 100-mesh sieve to obtain fine powder; and mixing the fine powder and flour uniformly according to weight ratio of 1:(7-10) to obtain the flour. The flour can nourish pancreas islet cells, improve pancreas islet function, reduce fasting and postprandial blood sugar and improve the living quality of patients who suffer from the diabetes.

Description

A kind of flour with treatment diabetes function and preparation method thereof
Technical field
The present invention relates to a kind of flour and preparation method thereof, particularly relate to a kind of flour with treatment diabetes function and preparation method thereof.
Background technology
Diabetes are a kind of whole body chronic metabolic disease that determined by gene.Its main feature is hyperglycaemia.According to the suggestion of the World Health Organization (WHO) and expert group of IDF (IDF), diabetes can be divided into 4 kinds of I type, II type, other specific types and gestational diabetes mellitus.
IDDM illness rate is far below type II diabetes.Because the disease symptom of children with type 1 diabetes mellitus is generally comparatively obvious, not easy to cause missed diagnosis.
During type II diabetes onset, symptom is more hidden, be difficult to obtain and make a definite diagnosis when onset, but its illness rate is higher.In recent years, the illness rate of countries in the world type II diabetes all has the trend sharply increasing, and the trend that in nearly 30 or five ten years, type II diabetes sharply increases is still difficult to alleviate.Also exist a large amount of blood sugar raise but do not reach diabetes diagnosis standard person outward.Their fasting blood-glucose, after the meal after 2 hours blood glucoses or clothes sugar 2 hours blood glucoses between euglycemia and diabetes diagnosis standard.Diabetes educational circles tends to this class to it is called as IGR (impaired glucose regulation, IGR) person's (vulnerable crowd) at present, and domestic have 1.48 hundred million at present.
The method of current treatment diabetes is " simply " very: the first, since there is no insulin or insufficient insulin in IDDM blood, that is with regard to hormone insulin.Such result is that pancreas function is replaced, has finally lost the function of excreting insulin.Second, in type II diabetes blood, blood sugar level is high, just take antidiabetic drug, mainly contain sulfonylureas, biguanides, alpha-glucosidase inhibitor, thiazolidinediones and non-sulfonylureas insulin succagoga etc., the curative effect of these chemicalses is clear and definite, but limitation and bad reaction exist equally, take antidiabetic drug, dosage is larger, and toxicity is also larger, involves liver kidney; Antidiabetic drug is between action period, and cell can not get nutrition, and cell viability goes down, and resists the ability of disease and accelerates to decline, and therefore complication rises.And the compliance aspect of Chinese medicine, natural drug long-term prescription shows certain advantage, particularly in recent years, from Chinese medicine, screening has the medicine of hypoglycemic activity and compound preparation research work progress rapidly, but the hypoglycemic of take is merely treated the method for diabetes as object, more and more the object for the treatment of can not be reached, promotion and application should be do not continued.The 3rd, auxiliary curing: motion, diet, to have a rest and change lifestyles be correct, just should be towards this direction effort, but is not enough to the diabetes that treatment has formed.Especially existing diet auxiliary curing, patient adopts diet control therapy for a long time, dare not eat, cause endotrophic composition picked-up imbalance, trophic disturbance, physique to decline, cause the appearance of various complication, bring a new difficult problem to again the treatment of diabetes and the control of complication, also become a difficult problem for global treatment diabetes simultaneously.The problem of diabetes be pancreas defunctionalization or reduced.Because the vigor of cell has declined, what show is that insulin is few, and blood sugar level has raise.The way of existing treatment diabetes: insulin injection and take antidiabetic drug for insulin disappearance and high these format surfaces of blood sugar, and the most basic pancreas function and cell viability are taken measures.Correct direction is to recover the normal function of pancreas and cell, recovers the instinct of human body and natural capacity of self-regulation.
Traditional diabetic diet control therapy, generally adopts and does not eat sugary food.
As everyone knows, sugar is one of indispensable important nutrient of human body, with the absorption of not absorbing sugar or few picked-up sugar or rely on medicine to reduce sugar, come mechanical control blood sugar to reach so-called criterion of acceptability, just think and well controlled diabetes, this is very large mistaken ideas.Many dieletic foodstuffs on market, the overwhelming majority develops under this theory, causes the reduction of patient's index number of price, physique to decline, and resistance reduces, and diabetes continue to develop, and cause serious complication.To patient, brought larger misery, for treatment from now on has also brought very large difficulty.
Summary of the invention
object of the present inventionbe to provide a kind of can nourishing pancreas islet cell, improve islet function, reduce on an empty stomach and postprandial blood sugar, improve the flour that contributes to treat diabetes of diabetes patient's quality of life.
Another object of the present invention is to provide a kind of preparation method with the flour for the treatment of diabetes function.
the present invention adopts following technical scheme:
A flour with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 10~12 parts of 14~17 portions of purslanes of 15~18 portions of Fructus Cornis of 20~25 portions of Chinese yams of 12~15 portions of Buddha's hands of 10~13 portions of mulberry fruits of the fruit of Chinese wolfberry, 5~10 parts of sealworts, 5~10 parts of tubers of dwarf lilyturf; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extract twice and with 160-180 mesh sieves, filter respectively, it is 1.23~1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23~1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour.
A preparation method for the flour for the treatment of diabetes function, is characterized in that it is comprised of following steps: the first step: take by weight: 10~12 parts of 14~17 portions of purslanes of 15~18 portions of Fructus Cornis of 20~25 portions of Chinese yams of 12~15 portions of Buddha's hands of 10~13 portions of mulberry fruits of the fruit of Chinese wolfberry, 5~10 parts of sealworts, 5~10 parts of tubers of dwarf lilyturf; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extract twice and with 160-180 mesh sieves, filter respectively, it is 1.23~1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23~1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour.
beneficial effect of the present invention: patient can make various wheaten foods by flour of the present invention that, with canteen use, every canteen is with approximately 100 grams.
The present invention treats diabetes and has following features:
1, safety: product of the present invention is selected not only edible but also natural plants that can be medicinal, has no side effect.
2, convenient: to use product of the present invention, patient's use, easy to carry.
3, evident in efficacy: use product of the present invention, can nourishing pancreas islet cell, improve islet function, reduce on an empty stomach and postprandial blood sugar.
In pharmaceutical formulation of the present invention, the effect of each bulk drug is:
buddha's hand: pungent, hardship, sweet, temperature, nontoxic, enter liver, spleen, stomach three warps, there are the multiple medicinal functions such as regulating qi-flowing for eliminating phlegm, cough-relieving dissipate-swelling, liver soothing and speen fortifying and stomach.
mulberry fruit: the sweet acid of taste, cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the intelligence development of nourishing heart.There is the enriching yin of enriching blood, promote the production of body fluid to quench thirst, the effect such as ease constipation is dry.
the fruit of Chinese wolfberry: nourishing liver and kidney, benefiting shrewd head.For consumptive disease essence, lose, soreness of waist and knee joint, dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear.Modern pharmacological research proof wolfberry fruit extract can significantly and lastingly reduce rat blood sugar, increases sugar tolerance.
chinese yam: taste is sweet, flat.Return spleen, lung, kidney channel.There is tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, the effect of the puckery essence of kidney tonifying.
fructus Corni: taste acid, puckery, tepor.Return liver, kidney channel.Have and tonify the liver and kidney, the effect that puckery essence is admittedly de-.
the tuber of dwarf lilyturf: taste is sweet, tepor, is slightly cold.The thoughts of returning home, lung, stomach warp.There is nourishing Yin and promoting production of body fluid, the effect that moistening lung clears away heart-fire.
sealwort: taste is sweet, flat.Return spleen, lung, kidney channel.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, the effect of kidney-nourishing.
purslane: taste acid, cold.Return liver, large intestine channel.Have clearing heat and detoxicating, cooling blood and hemostasis, the only effect of dysentery.
The present invention be take Buddha's hand as monarch drug in a prescription, and dispersing stagnated hepatoqi is complied with the property that liver bar reaches; Take matrimony vine, Chinese yam, mulberry fruit, sealwort, the tuber of dwarf lilyturf is ministerial drug, and supplementing qi and nourishing yin, coordinates the monarch drug in a prescription property of medicine, heightens the effect of a treatment; Take Fructus Corni, purslane is adjuvant.
Adopt the present invention to treat diabetes clinical treatment standard as follows:
Every day is the staple food that adopts flour of the present invention to make for every canteen, 200-400 grams of every days, within 8 weeks, is a course for the treatment of;
Effective standard is: use 1 course for the treatment of of flour of the present invention, and cardinal symptom's (many drinks, many foods, diuresis, weak) disappearance, fasting blood-glucose≤7.0mmol/L, or blood sugar is treated front decline >=30%, glycosylated hemoglobin < 6.5%.
Effectively standard is: uses 1 course for the treatment of of flour of the present invention, and obviously change of cardinal symptom's (many drinks, many foods, diuresis, weak), fasting blood-glucose≤8.3mmol/L or blood sugar are treated front decline >=10%, glycosylated hemoglobin 6.5~7.5%.
Invalid standard is: use 1 course for the treatment of of flour of the present invention, cardinal symptom's (many drinks, many foods, diuresis, weak) is not improved, and blood sugar decline does not reach above-mentioned standard, glycosylated hemoglobin >=7.5%.
Patient's 254 examples that are put to the test, are diagnosed as type II diabetes through hospital above county level, and without serious conscience kidney complication, at 27~65 years old age, edible 56 days continuously, test group was totally 254 examples, effective 62 examples, efficient 24.4%; Effective 138 examples, obvious effective rate 54.3%; Invalid 54 examples, inefficiency 21.2%, total effective rate 78.7%.
Model case:
What * *, female, 48 years old, diabetic history 2 years, is used after flour of the present invention, and dry is thirsty, fatigue, diuresis, drink transference cure more, apply after 4 weeks, fasting blood-glucose is down to 6.5mmol/L by 11.5mmol/L, and 2 hours blood glucoses are down to 11.1mmol/L by 20.2mmol/L, and application this product is looked into glycosylated hemoglobin after 8 weeks be 5.8%.
Shen * *, man, 40 years old, diabetic history 3 years, is used after flour of the present invention, and dry is thirsty, fatigue, diuresis, drink transference cure more, apply after 4 weeks, fasting blood-glucose is down to 6.0mmol/L by 13.1mmol/L, and 2 hours blood glucoses are down to 10.4mmol/L by 19.4mmol/L, and application this product is looked into glycosylated hemoglobin after 8 weeks be 6.4%.
Liu * *, female, 46 years old, diabetic history 4 years, is used after flour of the present invention, and dry is thirsty, fatigue, diuresis, drink transference cure more, apply after 4 weeks, fasting blood-glucose is down to 6.3mmol/L by 13.9mmol/L, and 2 hours blood glucoses are down to 11.1mmol/L by 18.2mmol/L, and application this product is looked into glycosylated hemoglobin after 8 weeks be 5.4%.
Du * *, man, 32 years old, diabetic history 2 years, is used after flour of the present invention, and dry is thirsty, fatigue, diuresis, drink transference cure more, apply after 4 weeks, fasting blood-glucose is down to 6.9mmol/L by 12.6mmol/L, and 2 hours blood glucoses are down to 10.3mmol/L by 19.3mmol/L, and application this product is looked into glycosylated hemoglobin after 8 weeks be 6.3%.
The specific embodiment
Embodiment 1
A flour with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 10 parts of the fruits of Chinese wolfberry, 15 parts, mulberry fruit, 20 parts of Buddha's hands, 16 parts of Chinese yams, 5 parts of Fructus Cornis, 10 parts of the tubers of dwarf lilyturf, 16 parts of sealworts, 12 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 180 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7 mix, obtain described flour.
A preparation method for the flour for the treatment of diabetes function, is characterized in that it is comprised of following steps: the first step: take by weight: 10 parts of the fruits of Chinese wolfberry, 15 parts, mulberry fruit, 20 parts of Buddha's hands, 16 parts of Chinese yams, 5 parts of Fructus Cornis, 10 parts of the tubers of dwarf lilyturf, 16 parts of sealworts, 12 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 160 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7 mix, obtain described flour.
Embodiment 2
A flour with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 13 parts of the fruits of Chinese wolfberry, 12 parts, mulberry fruit, 25 parts of Buddha's hands, 15 parts of Chinese yams, 10 parts of Fructus Cornis, 5 parts of the tubers of dwarf lilyturf, 14 parts of sealworts, 10 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 180 mesh sieves respectively, and it is 1.23g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:10 mix, obtain described flour.
A preparation method for the flour for the treatment of diabetes function, is characterized in that it is comprised of following steps: the first step: take by weight: 13 parts of the fruits of Chinese wolfberry, 12 parts, mulberry fruit, 25 parts of Buddha's hands, 15 parts of Chinese yams, 10 parts of Fructus Cornis, 5 parts of the tubers of dwarf lilyturf, 14 parts of sealworts, 10 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 160 mesh sieves respectively, and it is 1.23g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:10 mix, obtain described flour.
Embodiment 3
A flour with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 12 parts of the fruits of Chinese wolfberry, 12 parts, mulberry fruit, 24 parts of Buddha's hands, 18 parts of Chinese yams, 8 parts of Fructus Cornis, 8 parts of the tubers of dwarf lilyturf, 17 parts of sealworts, 11 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 180 mesh sieves respectively, and it is 1.25g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:8 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 1600 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.25g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:8 mix, obtain described flour.
A preparation method for the flour for the treatment of diabetes function, is characterized in that it is comprised of following steps: the first step: take by weight: 12 parts of the fruits of Chinese wolfberry, 12 parts, mulberry fruit, 24 parts of Buddha's hands, 18 parts of Chinese yams, 8 parts of Fructus Cornis, 8 parts of the tubers of dwarf lilyturf, 17 parts of sealworts, 11 parts of purslanes; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decocts 2 hours, adds for the second time the water of 8 times of weight, decocts 1.5 hours, decocts extract twice and filters with 180 mesh sieves respectively, and it is 1.25g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:8 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.25g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 100 mesh sieves and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:8 mix, obtain described flour.

Claims (2)

1. a flour with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 10~12 parts of 14~17 portions of purslanes of 15~18 portions of Fructus Cornis of 20~25 portions of Chinese yams of 12~15 portions of Buddha's hands of 10~13 portions of mulberry fruits of the fruit of Chinese wolfberry, 5~10 parts of sealworts, 5~10 parts of tubers of dwarf lilyturf; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extract twice and with 160-180 mesh sieves, filter respectively, it is 1.23~1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23~1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour.
2. a preparation method with the flour for the treatment of diabetes function, is characterized in that it is comprised of following steps: the first step: take by weight: 10~12 parts of 14~17 portions of purslanes of 15~18 portions of Fructus Cornis of 20~25 portions of Chinese yams of 12~15 portions of Buddha's hands of 10~13 portions of mulberry fruits of the fruit of Chinese wolfberry, 5~10 parts of sealworts, 5~10 parts of tubers of dwarf lilyturf; Second step: said components raw material is mixed, and boiling twice, adds the water of 10 times of weight for the first time, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extract twice and with 160-180 mesh sieves, filter respectively, it is 1.23~1.26g/cm that filtrate is concentrated into density 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour;
Or said components raw material is mixed, add 70% alcohol reflux and extract twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23~1.26g/cm 3, obtain medicinal extract, gained medicinal extract through vacuum drying, was pulverized to 80-100 mesh sieve and was obtained fine powder, by fine powder and flour by ratio of weight and the number of copies the ratio of 1:7~10 mix, obtain described flour.
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何翔玲.《浅谈糖尿病用药规律》.《新中医》.1996,(第11期),第51页.

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