CN102114206A - Powder capable of restoring function of pancreatic islet and preparation method thereof - Google Patents
Powder capable of restoring function of pancreatic islet and preparation method thereof Download PDFInfo
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Abstract
The invention relates to powder capable of restoring the function of the pancreatic islet and the preparation method thereof. The powder is made by adopting the following steps that mulberry fruit, Fructus Lycii, Fructus Citri Sarcodactylis, Poria, pumpkin, Semen Coicis, Radix Puerariae, Fructus Citri, Radix Ginseng and Radix Astragali are weighed according to the parts by weight; the above component materials are mixed and decocted in water twice, wherein 10 weight times of water is added for the first time and the decoction time is 2 hours, and 8 weight times of water is added for the second time and the decoction time is 1.5 hours; the solution extracted from twice decoctions is filtered through a 160 to 180 mesh sieve respectively, and filtrate is concentrated until the density ranges from 1.23 g/cm3 to 1.26 g/cm3 to produce extract; the extract is vacuumized, pulverized and sieved through a 80 to 100 mesh sieve to produce fine powder; the fine powder is uniformly mixed with cooked millet powder and cooked sesame seed according to the weight fraction mixture ratio of 1:3 to 6:0.5 to 1, and the powder is obtained. By adopting the powder, nutrients can be supplied to the islet cells, the function of the pancreatic islet is improved, the glycemic indexes of foods can be effectively controlled, the fasting blood glucose level and the postprandial blood glucose level are lowered, the dosage of antidiabetic drugs is reduced, and the life quality is improved.
Description
Technical field
The present invention relates to a kind of powder and preparation method thereof, particularly relate to a kind of have can recover powder of islet function and preparation method thereof.
Background technology
Diabetes are a kind of whole body chronic metabolic disease by the gene decision.Its main feature is a hyperglycemia.According to the suggestion of The World Health Organization (WHO) and expert group of IDF (IDF), diabetes can be divided into 4 kinds of I type, II type, other specific types and gestational diabetes.
The type prevalence is far below type.Because the disease symptom of child's type is generally comparatively obvious, is difficult for failing to pinpoint a disease in diagnosis.
Symptom is more hidden during the type onset, be difficult in to obtain when just sending out to make a definite diagnosis, but its prevalence is higher.In recent years, the prevalence of countries in the world type all has the trend of rapid increase, and the trend that type sharply increases in nearly 30 or five ten years still is difficult to alleviate.Also there are a large amount of blood sugar increasing outward but do not reach diabetes diagnosis standard person.Their fasting glucose, 2 hours after the meal blood glucose or back 2 hours blood glucose of clothes sugar are between euglycemia and diabetes diagnosis standard.It is that (domestic have 1.48 hundred million to IGR at present for impaired glucose regulation, IGR) person's (vulnerable crowd) that present diabetes educational circles tends to this class person.
The method of present treatment diabetes is " simply " very: the first, since do not had insulin or insufficient insulin in the type blood, that is with regard to external insulin injection.Such result is that pancreatic function is replaced, has finally lost the function of excreting insulin.Second, blood sugar level height in the type blood, just take antidiabetic drug, mainly contain sulphanylureas, biguanides, alpha-glucosidase inhibitor, thiazolidinediones and non-sulphanylureas insulin succagoga etc., the curative effect of these chemicalses is clear and definite, but limitation and untoward reaction exist equally, as: the prolonged application insulin easily produces insulin resistant, and sulphanylureas causes that hypoglycemia, biguanides cause that lactic acidosis, α glycosidase inhibitor cause gastrointestinal side effect or the like.Be blocking-up or the sugar that the slows down speed that enters blood outwardly, the result of detection be in the blood blood glucose level drops get off, but can't solve root problem.Take antidiabetic drug, dosage is big more, and toxicity is also big more, involves Liver and kidney; Antidiabetic drug is between action period, and cell can not get nutrition, and cell viability goes down, and resists the ability of disease and quickens to descend, and therefore complication rises.And the compliance aspect of Chinese medicine, natural drug long-term prescription shows certain advantage, particularly in recent years, it is rapid to screen medicine and compound preparation research work progress with hypoglycemic activity from Chinese medicine, research focus and exploitation direction have been become, but simple is the method that purpose is treated diabetes with the blood sugar lowering, more and more can not reach the purpose of treatment, should not continue promotion and application.The 3rd, auxiliary treatment: motion, diet, to have a rest and change lifestyles be correct, just should be towards this direction effort, but be not enough to treat the diabetes that formed.Especially existing diet auxiliary treatment, the patient adopts the diet control therapy for a long time, dare not eat, cause endotrophic composition picked-up imbalance, nutritional disorder, body constitution to descend, cause the appearance of various complication, bring a new difficult problem for again the control of treatment of diabetes and complication, also become the difficult problem of global treatment diabetes simultaneously.The problem of diabetes is not because blood glucose height in the blood in fact, neither lack because of insulin in the blood, but because the defunctionalization of pancreas or reduced because the vigor of cell has descended, show be insulin few and blood sugar level raise.The way of existing treatment diabetes: insulin injection and take antidiabetic drug at insulin disappearance and high these format surfaces of blood glucose, and the most basic pancreatic function and cell viability are taken measures.Correct direction is to recover the normal function of pancreas and cell, recovers the instinct of human body and natural capacity of self-regulation.
Traditional diabetic diet control therapy, generally adopt and do not eat sacchariferous food, sugarfree foods on the market adopts the method for not sugaring or adds not sweeting agent such as sacchariferous xylitol, increases the mouthfeel of sweet taste merely, causes diabetics saccharide source disappearance.
As everyone knows, sugar is one of indispensable important nutrient of human body, come the blood sugar control of machinery to reach so-called criterion of acceptability with the absorption of not absorbing sugar or few picked-up sugar or rely on medicine to reduce sugar, just think that better controlled lived diabetes, this is very big mistaken ideas.Many dieletic foodstuffs on the market, the overwhelming majority develops under this theory, even some is mixed the genuine with the fictitious, even more serious is, the unscientific propaganda of many sugarfree foods producer causes unnecessary the seeing of patient " sugar " fear, cause the reduction of patient's index number of price, body constitution to descend, resistance reduces, and diabetes continue development, and cause severe complications.Brought bigger misery to the patient, for from now on treatment has also brought very big difficulty.
Summary of the invention
Purpose of the present inventionProvide a kind of can the nourishing pancreas islet cell, improve islet function, control the sugared index of life of food effectively, reduce on an empty stomach and post-prandial glycemia, reduce the consumption of treatment diabetes medicament, that improves the quality of living has a powder that can recover islet function.
Another object of the present invention provides a kind of preparation method with the powder that can recover islet function.
The present invention adopts following technical scheme:
A kind of have a powder that can recover islet function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 12～15 parts in Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts in Poria, 12～14 parts in Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized the 80-100 mesh sieve and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized the 80-100 mesh sieve and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder.
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 12～15 parts in Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts in Poria, 12～14 parts in Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized the 80-100 mesh sieve and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized the 80-100 mesh sieve and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder.
Beneficial effect of the present inventionBe: the patient can be with the hot water of powder of the present invention according to 3～5 times of every 50g this product addings, and the back that stirs is directly edible.Every day edible this product 50～100g.
Powder treatment diabetes of the present invention have following characteristics:
1, safety: product of the present invention is selected natural plants not only edible but also can be medicinal for use, has no side effect environmental protection.
2, convenient: use product of the present invention, the patient is easy to use and carry.
3, evident in efficacy: use product of the present invention, can make general patient's glycemic control steady, the nourishing pancreas islet cell improves islet function.
In the medicine powder prescription of the present invention, the effect of each crude drug is:
Fructus Citri Sarcodactylis:Suffering, hardship, sweet, temperature, nontoxic, go into liver, spleen, stomach three warps, multiple medicinal functions such as activating QI to eliminate phlegm, cough-relieving relieving distension, the liver soothing and the spleen invigorating stomach function regulating are arranged.
Fructus Lycii:Nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.Modern pharmacological research proof Fructus Lycii extract can significantly and lastingly reduce rat blood sugar, increases carbohydrate tolerance.
Fructus Mori:Sweet in the mouth acid, cold nature is gone into the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving.Has the YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, effect such as intestine moistening is dry.
Radix Puerariae: sweet in the mouth, suffering, cold.Return spleen, stomach, lung meridian.Has expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, the effect of alcoholic intoxication.
Semen Coicis: sweet in the mouth, light, cold.Return spleen, stomach, lung meridian.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the effect of detoxicating and resolving stagnation of pathogens.
Fructus Citri: acrid in the mouth, hardship, acid, temperature.Return liver, spleen, lung meridian.Has depressed liver-energy dispersing and QI regulating, alleviating distention in middle-JIAO, clears phlegm.
Poria: sweet in the mouth is light, flat.GUIXIN, lung, spleen, kidney channel.Has promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of mind calming.
Fructus Cucurbitae moschatae:Carry according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": Fructus Cucurbitae moschatae is warm in nature, and sweet in the mouth is nontoxic, goes into spleen, stomach two warps, the energy moistening lung qi-benefitting, and the row of reducing phlegm is dense, and the anthelmintic detoxifcation is controlled and is coughed Zhichuan, treats lung abscess and constipation, and effects such as diuresis, beauty treatment are arranged.Squash polyoses is a kind of nonspecific immunity strengthening agent, can improve body's immunological function, promotes cytokine to generate, and by approach such as complement activations immune system is brought into play many-sided regulatory function.
Radix Ginseng:Sweet in the mouth, little hardship, flat; Return spleen, lung, heart channel.Have strongly invigorating primordial QI, multiple arteries and veins takes off invigorating the spleen to benefit the lung, the effect of promoting the production of body fluid and inducing sedation of the mind admittedly.
The Radix Astragali:Sweet in the mouth, temperature; Return lung, spleen channel.Has invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effect of expelling pus and promoting granulation.
It is as follows to adopt the present invention to recover islet function clinical treatment standard:
Every day, edible powder of the present invention was 1-2 times, each 20-50 grams, and 8 weeks were a course of treatment;
The standard of produce effects is: use 1 course of treatment of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) disappears, fasting glucose≤7.0mmol/L, or blood glucose descends 〉=30%, glycolated hemoglobin＜6.5% before the treatment.
Effectively standard is: uses 1 course of treatment of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) obviously changes, the decline 〉=10% before the treatment of fasting glucose≤8.3mmol/L or blood glucose, glycolated hemoglobin 6.5～7.5%.
Invalid standard is: use 1 course of treatment of powder of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) does not have obviously and improves, and blood glucose descends and do not reach above-mentioned standard, glycolated hemoglobin 〉=7.5%.
Patient's 314 examples that are put to the test are diagnosed as type through hospital above county level, no severe cardiac Liver and kidney complication, and 27～70 years old age, to take continuously 56 days, experimental group is totally 314 examples, effective 90 examples, effective percentage 28.6%; Produce effects 156 examples, obvious effective rate 49.7%; Invalid 68 examples, inefficiency 21.6%, total effective rate 78.3%.
Model case:
Lee * *, the woman, 48 years old, diabetic history 2 years, use powder of the present invention after, xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, after using for 4 weeks, fasting glucose is reduced to 7.0mmol/L by 11.5mmol/L, and blood glucose was reduced to 10.0mmol/L by 19.2mmol/L in 2 hours, and taking this product, to look into glycolated hemoglobin after 8 weeks be 6.0%.
Virgin * *, the man, 53 years old, diabetic history 3 years, use powder of the present invention after, xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, after using for 4 weeks, fasting glucose is reduced to 6.8mmol/L by 12.6mmol/L, and blood glucose was reduced to 10.2mmol/L by 19.0mmol/L in 2 hours, and taking this product, to look into glycolated hemoglobin after 8 weeks be 6.2%.
Open * *, the man, 56 years old, diabetic history 4 years, use powder of the present invention after, xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, after using for 4 weeks, fasting glucose is reduced to 6.9mmol/L by 13.4mmol/L, and blood glucose was reduced to 10.1mmol/L by 20.2mmol/L in 2 hours, and taking this product, to look into glycolated hemoglobin after 8 weeks be 6.3%.
Liu * *, the man, 51 years old, diabetic history 2 years, use powder of the present invention after, xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, after using for 4 weeks, fasting glucose is reduced to 6.3mmol/L by 11.4mmol/L, and blood glucose was reduced to 10.6mmol/L by 18.2mmol/L in 2 hours, and taking this product, to look into glycolated hemoglobin after 8 weeks be 5.9%.
The specific embodiment
Embodiment 1
A kind of have a powder that can recover islet function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 12 parts in Fructus Mori, 18 parts of Fructus Lycii, 23 parts of Fructus Citri Sarcodactylis, 15 parts in Poria, 14 parts in Fructus Cucurbitae moschatae, 10 parts of Semen Coiciss, 11 parts of Radix Puerariaes, 16 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.23g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 80 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3:1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 80 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3:1, promptly get described powder.
Embodiment 2
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 15 parts in Fructus Mori, 16 parts of Fructus Lycii, 20 parts of Fructus Citri Sarcodactylis, 17 parts in Poria, 13 parts in Fructus Cucurbitae moschatae, 11 parts of Semen Coiciss, 12 parts of Radix Puerariaes, 15 parts of Fructus Citris, 7 parts of Radix Ginsengs, 10 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 160 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 100 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:4:0.5, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 100 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:4:0.5, promptly get described powder.
Embodiment 3
A kind of have a powder that can recover islet function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 13 parts in Fructus Mori, 15 parts of Fructus Lycii, 25 parts of Fructus Citri Sarcodactylis, 16 parts in Poria, 12 parts in Fructus Cucurbitae moschatae, 13 parts of Semen Coiciss, 10 parts of Radix Puerariaes, 18 parts of Fructus Citris, 6 parts of Radix Ginsengs, 11 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.24g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 100 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:6:0.8, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.24g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 100 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:6:0.8, promptly get described powder.
Embodiment 4
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 14 parts in Fructus Mori, 15 parts of Fructus Lycii, 22 parts of Fructus Citri Sarcodactylis, 17 parts in Poria, 12 parts in Fructus Cucurbitae moschatae, 13 parts of Semen Coiciss, 12 parts of Radix Puerariaes, 17 parts of Fructus Citris, 6 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 160 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 100 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:5:1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 100 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:5:1, promptly get described powder.
Embodiment 5
A kind of have a powder that can recover islet function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 15 parts in Fructus Mori, 18 parts of Fructus Lycii, 25 parts of Fructus Citri Sarcodactylis, 15 parts in Poria, 14 parts in Fructus Cucurbitae moschatae, 10 parts of Semen Coiciss, 11 parts of Radix Puerariaes, 16 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.25g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 80 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3:0.5, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.25g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 80 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3:0.5, promptly get described powder.
Embodiment 6
A kind of preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 12 parts in Fructus Mori, 18 parts of Fructus Lycii, 20 parts of Fructus Citri Sarcodactylis, 17 parts in Poria, 14 parts in Fructus Cucurbitae moschatae, 12 parts of Semen Coiciss, 10 parts of Radix Puerariaes, 18 parts of Fructus Citris, 5 parts of Radix Ginsengs, 12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized 100 mesh sieves and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:4:0.7, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized 100 mesh sieves and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:4:0.7, promptly get described powder.
Claims (2)
1. one kind has the powder that can recover islet function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 12～15 parts in Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts in Poria, 12～14 parts in Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized the 80-100 mesh sieve and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized the 80-100 mesh sieve and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder.
2. preparation method with the powder that can recover islet function, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 12～15 parts in Fructus Mori, 15～18 parts of Fructus Lycii, 20～25 parts of Fructus Citri Sarcodactylis, 15～17 parts in Poria, 12～14 parts in Fructus Cucurbitae moschatae, 10～13 parts of Semen Coiciss, 10～12 parts of Radix Puerariaes, 15～18 parts of Fructus Citris, 5～7 parts of Radix Ginsengs, 10～12 parts of the Radixs Astragali; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, gained extractum through vacuum drying, was pulverized the 80-100 mesh sieve and was got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, with gained extractum through vacuum drying,, pulverized the 80-100 mesh sieve and got fine powder, fine powder and processed millet powder, Semen Sesami Nigrum is even according to the mixed of ratio of weight and number 1:3～6:0.5～1, promptly get described powder.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055156A (en) * | 2012-12-28 | 2013-04-24 | 六安同济生生物科技有限公司 | Compound dendrobium huoshanense, cistanche and ganoderma extract and production process thereof |
| CN111838521A (en) * | 2020-03-16 | 2020-10-30 | 杨波 | Medicated diet functional flour assisting in reducing blood sugar, regulating lipid, losing weight and relieving insulin resistance |
| CN114431465A (en) * | 2022-01-24 | 2022-05-06 | 和也健康科技有限公司 | Blood glucose reducing RS3 composite brewing powder |
-
2010
- 2010-12-31 CN CN201010618931.XA patent/CN102114206B/en active Active
Non-Patent Citations (2)
| Title |
|---|
| 屠庆祝等: "浅谈中药治疗糖尿病的用药规律", 《中医药临床杂志》 * |
| 未知: "【供应】 供应疏糖粉(疏糖粉)", 《食品产业网，网址：HTTP://WWW.FOODQS.CN/TRADES/TRADEPAGE/TRADE_VIEW_1089459.HTML》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055156A (en) * | 2012-12-28 | 2013-04-24 | 六安同济生生物科技有限公司 | Compound dendrobium huoshanense, cistanche and ganoderma extract and production process thereof |
| CN111838521A (en) * | 2020-03-16 | 2020-10-30 | 杨波 | Medicated diet functional flour assisting in reducing blood sugar, regulating lipid, losing weight and relieving insulin resistance |
| CN114431465A (en) * | 2022-01-24 | 2022-05-06 | 和也健康科技有限公司 | Blood glucose reducing RS3 composite brewing powder |
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| CN102114206B (en) | 2014-06-11 |
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