CN103690841A - Traditional Chinese medicine for treating diarrhea of weaned piglet in summer and preparation method thereof - Google Patents
Traditional Chinese medicine for treating diarrhea of weaned piglet in summer and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine for treating diarrhea of a weaned piglet in summer and a preparation method thereof. The traditional Chinese medicine comprises the following Chinese herbal raw materials in part by weight: 6-12 parts of white atractylodes rhizome, 6-12 parts of poria cocos, 6-12 parts of dried orange peel, 6-12 parts of mangnolia officinalis, 6-12 parts of bitter orange, 6-12 parts of fructus aurantii, 6-12 parts of cyperus rotundus, 6-12 parts of hawthorn, 6-12 parts of medicated leaven, 6-12 parts of malt, 6-12 parts of rhizoma pinelliae preparatum, 6-12 parts of white lablab bean, 6-12 parts of Chinese yam, 6-12 parts of lotus seed and 6-12 parts of montmorillonite, 6-12 parts of jasminum elongatum, 6-12 parts of Chinese knotweed herb, 6-12 parts of gastrodia elata, 6-12 parts of scutellaria baicalensis, 6-12 parts of Ilicis routundae cortex and 6-12 parts of areca nut. Veterinary clinical test results show that the weaned piglet diarrhea curing rate is 97.5% for the traditional Chinese medicine group, while the weaned piglet diarrhea curing rate is 85% for a gentamicin group.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine of diarrhea of weaned piglets in summer and preparation method thereof that breaks for the treatment of.
Background technology
Piglet diarrhea all has and has a strong impact on piglet survival ratio and later stage weightening finish, becomes the important diseases of restriction pig industry development.Diarrhoea phenomenon occurred in after wean 1 week very common, mortality rate often reaches 10%-20%, and high reaches more than 40%.The antibiosis class drug development for the treatment of piglet diarrhoea is rapid, and be widely used in veterinary clinic, and the dosage of use is also increasing, and Resistant strain also increases gradually, to this disease of clinical treatment, cause many unfavorable factors, the food safety causing, environmental pollution and drug resistance problem receive publicity day by day.Many developed countries successively ban use of antibiotic as feed additive, utilize green barrier to cut down simultaneously and even stop the import meat from China, bring about great losses to China's meat products outlet.And the contained active substance of Chinese medicine compound has many target spots, can enhancing human body immunity function, improve animal anti-stress, anti-disease ability, improve breeding performonce fo animals, and there is low-residual, be difficult for producing the advantages such as drug resistance.Therefore developing treatment diarrhea of weaned piglets Chinese medicine compound in summer has great importance to the pig industry of China.
In recent years, China's piglet diarrhea is very general, is one of difficult problem of puzzle pig industry development.During modernized pig raising is produced, usually take the way of early weaning to shorten the age of sucking of sow, improve the fertility performance of sow; But early stage disconnected throwing away, often brings a series of harmful effects to piglet, wherein after wean, l week there is diarrhoea phenomenon very common.According to investigations, piglet accounts for 39.8% of the dead sum of piglet because of the death of suffering from diarrhoea.30 kilograms of following piglets, average of the whole year sickness rate 46.5%, mortality rate 10.30%, the economic loss number that estimation China causes every year is thus with hundred million yuan.The generation of this disease is popular in causing the direct death of pig, and also remote-effects, to the growth promoter of the pig of recovering, become the important restriction factor that affects the economic benefit of raising pigs.Be diarrhea of weaned piglets season occurred frequently summer, is also the season occurred frequently of ablactational baby pig death.
In recent years, the antibiosis class drug development for the treatment of piglet diarrhoea is rapid, and be widely used in veterinary clinic, the dosage using is also increasing, Resistant strain also increases gradually, to this disease of clinical treatment, cause many unfavorable factors, the food safety causing, environmental pollution and drug resistance problem receive publicity day by day.Many developed countries successively ban use of antibiotic as feed additive, utilize green barrier to cut down simultaneously and even stop the import meat from China, bring about great losses to China's meat products outlet.Cause the reason more complicated of diarrhea of weaned piglets, mainly comprise nutrition physiology feature (digestive function is unsound, the impact of ablactation stress external environment) and the disease factor (antibacterial and viral infection) of piglet.Therefore, exploitation have wide spectrum, antimicrbial power strong, be difficult for producing drug resistance, medicine that toxic and side effects is little, being that veterinary circle is anxious waits to need the problem that solves.And the product that the Chinese herbal medicine distinctive Chinese medical theory that is China combines with practice, its aboundresources, with a long history, its effect and safety have been approved by people, as animal feed additive, are that a large focus of studying carefully is hacked in the world in recent years.Its contained active substance has many target spots, can enhancing human body immunity function, improve animal anti-stress, anti-disease ability, and improve breeding performonce fo animals, and there is low-residual, be difficult for producing the advantages such as drug resistance.
Summary of the invention
The object of the invention is provides a kind of diarrhea of weaned piglets Chinese medicine in summer and preparation method thereof for the treatment of for the deficiencies in the prior art.
The object of the present invention is achieved like this:
Treat a Chinese medicine for diarrhea of weaned piglets in summer, by the raw material of Chinese medicine medicine of following weight portion, made:
Rhizoma Atractylodis Macrocephalae 6-12 part, Poria 6-12 part, Pericarpium Citri Reticulatae 6-12 part, Cortex Magnoliae Officinalis 6-12 part, Fructus Aurantii Immaturus 6-12 part, Fructus Aurantii 6-12 part, Rhizoma Cyperi 6-12 part, Fructus Crataegi 6-12 part, Massa Medicata Fermentata 6-12 part, Fructus Hordei Germinatus 6-12 part, Rhizoma Pinelliae Preparatum 6-12 part, Semen Lablab Album 6-12 part, Rhizoma Dioscoreae 6-12 part, Semen Nelumbinis 6-12 part, Montmorillonitum 6-12 part, Herba Oxalidis strictae 6-12 part, Herb Polygoni Chinensis 6-12 part, to sitting leaf 6-12 part, Radix Scutellariae 6-12 part, Cortex Ilicis Rotundae 6-12 part, Semen Arecae 6-12 part.
Preferably, the Chinese medicine of above-mentioned treatment diarrhea of weaned piglets in summer, by the raw material of Chinese medicine medicine of following weight portion, made:
9 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts, Poria, 9 parts of Pericarpium Citri Reticulataes, 9 parts of Cortex Magnoliae Officinalis, 9 parts of Fructus Aurantii Immaturuss, 9 parts of Fructus Aurantiis, 9 parts of Rhizoma Cyperis, 9 parts of Fructus Crataegis, 9 parts of Massa Medicata Fermentata, 9 parts, Fructus Hordei Germinatus, 9 parts of Rhizoma Pinelliae Preparatum, 9 parts of Semen Lablab Albums, 9 parts of Rhizoma Dioscoreaes, 9 parts, Semen Nelumbinis, 9 parts of Montmorillonitums, 9 parts of Herba Oxalidis strictaes, 9 parts of Herb Polygoni Chinensiss, to sitting 9 parts, leaf, 9 parts of Radix Scutellariaes, 9 parts of Cortex Ilicis Rotundaes, 9 parts of Semen Arecaes.
The preparation method of the Chinese medicine of above-mentioned treatment diarrhea of weaned piglets in summer, comprises the steps:
(a) Rhizoma Atractylodis Macrocephalae, Poria, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Fructus Aurantii, Rhizoma Cyperi, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Rhizoma Pinelliae Preparatum, Semen Lablab Album, Rhizoma Dioscoreae, Semen Nelumbinis, Herba Oxalidis strictae, Herb Polygoni Chinensis, to sitting leaf, Radix Scutellariae, Cortex Ilicis Rotundae, Semen Arecae, decoct with water 2 times, the water that adds for the first time 8 times of amounts of drug weight, decoct 1.5 hours, the water that adds for the second time 6 times of amounts of drug weight, decoct 1 hour, collecting decoction, filter, filtrate is condensed into the clear paste that density is 1.15-1.19, clear paste drying under reduced pressure, pulverize, cross 100 mesh sieves, be prepared into extract powder;
(b) Montmorillonitum breaks into fine powder;
(c) the Montmorillonitum fine powder that the extract powder that prepared by step (a) is prepared with step (b) mixes, and adds starch and sucrose, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
In the Chinese medicine for the treatment of diarrhea of weaned piglets in summer of the present invention:
Herba Oxalidis strictae is dry tender stem and the leaf of Oleaceae jasmine Herba Oxalidis strictae Jasminum elongatum (Bergius) Wiid..Because it is good at treating abdominal pain due to damp-heat dysentery, therefore named Herba Oxalidis strictae.
Herb Polygoni Chinensis calls wing land productivity, Linesless charcoal star, Linesless charcoal rattan, plain rice rattan, letter meal rattan, the herb of polygonaceae plant Herb Polygoni Chinensis Polygonum chinense L..Have QI invigorating, promoting the circulation of blood, dispels the wind, antipyretic effect.
To sitting silk ball, four on leaf another name leaf, reporting passes, Herba Alternantherae sessilis, bone leaf, is the rough Auricled Hedyotis Herb Hedyotis of Rubiaceae plants of Hedyotis meropodium uncinella Hook. et Arn. Var. scabrida[Oldenlandia uncinella (Hook et Arn.) O. Ktunze var. scabrida (Franch.) Hand.-Mazz.] dry herb.Nature and flavor are sweet, pungent, cool.There is expelling wind and removing dampness, spleen invigorating removing food stagnancy, the effect of heat-clearing and toxic substances removing.
Cortex Ilicis Rotundae is bark or the root bark of holly plant Ilex rotunda Thunb. Ilex rotunda Thunb..There is heat-clearing and toxic substances removing; Dampness removing; The effect of pain relieving.
All the other raw material of Chinese medicine medicines are the kind of a record of pharmacopeia.
Chinese veterinarian's theory is thought the many and being invaded by exogenous pathogen of piglet diarrhea, and internal damage caused by infantile dyspepsia and weakness of the spleen and stomach are in close relations, and feeding and management is not good in addition, causes transformation and transportation of the spleen and stomach not normal, indigestion, clear QI being mixed up with turbid QI and having loose bowels.Be diarrhea of weaned piglets season occurred frequently summer, the diarrhea of weaned piglets in summer, be mostly due to improper feeding or environment disinfected inadequate, due to infection.The principle of controlling according to the dialectical opinion of Chinese veterinarian, " the spleen strengthening and damp drying, heat-clearing and toxic substances removing are changed turbid dysentery relieving " are the cardinal principle for the treatment of piglet diarrhea.During treatment, according to traditional Chinese veterinary medicine theory and practice experience, piglet diarrhea is carried out to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, from strengthening the spleen and nourishing the stomach, heat-clearing and toxic substances removing, change the aspect prescriptions such as turbid dysentery relieving.
The present invention is the cause of disease according to diarrhea of weaned piglets, with reason spleen stomach function regulating, heat-clearing and toxic substances removing, change the principle prescription of turbid dysentery relieving, this compound recipe has the effect of conditioning intestine of young pigs microecological environment, enhancing immunity. for prevention and treatment diarrhea of weaned piglets in summer, there is significant effect; In daily ration, adding proportion is low, safe noresidue.
Veterinary clinic result of the test shows, treatment by Chinese herbs diarrhea of weaned piglets in summer cure rate of the present invention is 97.5%, and gentamycin matched group is 85.0%.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a Chinese medicine for diarrhea of weaned piglets in summer, write out a prescription as follows:
Rhizoma Atractylodis Macrocephalae 90g, Poria 90g, Pericarpium Citri Reticulatae 90g, Cortex Magnoliae Officinalis 90g, Fructus Aurantii Immaturus 90g, Fructus Aurantii 90g, Rhizoma Cyperi 90g, Fructus Crataegi 90g, Massa Medicata Fermentata 90g, Fructus Hordei Germinatus 90g, Rhizoma Pinelliae Preparatum 90g, Semen Lablab Album 90g, Rhizoma Dioscoreae 90g, Semen Nelumbinis 90g, Montmorillonitum 90g, Herba Oxalidis strictae 90g, Herb Polygoni Chinensis 90g, to sitting leaf 90g, Radix Scutellariae 90g, Cortex Ilicis Rotundae 90g, Semen Arecae 90g.
The preparation method of the Chinese medicine of above-mentioned treatment diarrhea of weaned piglets in summer, comprises the steps:
(a) Rhizoma Atractylodis Macrocephalae, Poria, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Fructus Aurantii, Rhizoma Cyperi, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Rhizoma Pinelliae Preparatum, Semen Lablab Album, Rhizoma Dioscoreae, Semen Nelumbinis, Herba Oxalidis strictae, Herb Polygoni Chinensis, to sitting leaf, Radix Scutellariae, Cortex Ilicis Rotundae, Semen Arecae, decoct with water 2 times, the water that adds for the first time 8 times of amounts of drug weight, decoct 1.5 hours, the water that adds for the second time 6 times of amounts of drug weight, decoct 1 hour, collecting decoction, filter, filtrate is condensed into the clear paste that density is 1.15-1.19, clear paste drying under reduced pressure, pulverize, cross 100 mesh sieves, be prepared into extract powder;
(b) Montmorillonitum breaks into fine powder;
(c) the Montmorillonitum fine powder that the extract powder that prepared by step (a) is prepared with step (b) mixes, and adds starch and sucrose, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
Usage and dosage: each 1 bag of every piglet, every day 2 times.Water-soluble rear gavage or mix in piglet diet and take.
Embodiment 2
Treat a Chinese medicine for diarrhea of weaned piglets in summer, write out a prescription as follows:
Rhizoma Atractylodis Macrocephalae 60g, Poria 120g, Pericarpium Citri Reticulatae 60g, Cortex Magnoliae Officinalis 120g, Fructus Aurantii Immaturus 60g, Fructus Aurantii 120g, Rhizoma Cyperi 60g, Fructus Crataegi 120g, Massa Medicata Fermentata 60g, Fructus Hordei Germinatus 120g, Rhizoma Pinelliae Preparatum 60g, Semen Lablab Album 120g, Rhizoma Dioscoreae 60g, Semen Nelumbinis 120g, Montmorillonitum 60g, Herba Oxalidis strictae 120g, Herb Polygoni Chinensis 60g, to sitting leaf 120g, Radix Scutellariae 60g, Cortex Ilicis Rotundae 120g, Semen Arecae 60g.
Preparation method is with embodiment 1.Prepare altogether 100 bags, every bag heavy 1g.
Usage and dosage: each 1 bag of every piglet, every day 2 times.Water-soluble rear gavage or mix in piglet diet and take.
Embodiment 3
Treat a Chinese medicine for diarrhea of weaned piglets in summer, write out a prescription as follows:
Rhizoma Atractylodis Macrocephalae 120g, Poria 60g, Pericarpium Citri Reticulatae 120g, Cortex Magnoliae Officinalis 60g, Fructus Aurantii Immaturus 120g, Fructus Aurantii 60g, Rhizoma Cyperi 120g, Fructus Crataegi 60g, Massa Medicata Fermentata 120g, Fructus Hordei Germinatus 60g, Rhizoma Pinelliae Preparatum 120g, Semen Lablab Album 60g, Rhizoma Dioscoreae 120g, Semen Nelumbinis 60g, Montmorillonitum 120g, Herba Oxalidis strictae 120g, Herb Polygoni Chinensis 60g, to sitting leaf 120g, Radix Scutellariae 60g, Cortex Ilicis Rotundae 120g, Semen Arecae 60g.
Preparation method is with embodiment 1.Prepare altogether 100 bags, every bag heavy 1g.
Usage and dosage: each 1 bag of every piglet, every day 2 times.Water-soluble rear gavage or mix in piglet diet and take.
It is sick that piglet diarrhea refers to that the piglet at 1～3 monthly age be take the mass-sending that dysentery is cardinal symptom, and especially after wean, in 10～15d, sickness rate is quite high, to pig industry, has brought very large loss.Get the Chinese medicine that the piglet at 1～3 monthly age prepares the embodiment of the present invention and test, test period summer in 2013, result is as follows:
The test of experimental example 1 treatment diarrhea of weaned piglets in summer
1.1 test drug
Chinese medicine prepared by the embodiment of the present invention.
Gentamicin injection liquid: 2ml/ props up (lot number: 200120621), Henan Furen Pharmaceutical Group Co., Ltd. produces.
1.2 experimental animal
80 of the ablactational baby pig that selection trouble is suffered from diarrhoea in swinery.
1.3 EXPERIMENTAL DESIGN
80 ablactational baby pig that suffer from diarrhoea are divided into two groups, 40 every group, use respectively Traditional Chinese medicine compound composition and gentamycin to treat.The extract oral for the treatment of of the present invention diarrhea of weaned piglets in summer, every of every day 2 times,, each 1 bag, use 10ml water dissolution, gavage for every bag; Gentamycin matched group, gavage injection liquid of gentamicin, every of every day 2 times, each 2ml
1.4 testing index
Cure rate accounts for the percentage rate of a treatment number for curing a number.Curing a number refers to the interior transference cure of medication 3d or alleviates; After a number of failing to respond to any medical treatment refers to medication, the interior symptom of 3d does not alleviate or death.
1.5 result
Table 2 diarrhea of weaned piglets therapeutic test result
| Group | A prevention number | Cure a number | Cure rate (%) |
| Chinese drug-treated group of the present invention | 40 | 39 | 97.5 |
| Gentamycin group | 40 | 34 | 85.0 |
As seen from Table 2, treatment by Chinese herbs diarrhea of weaned piglets in summer cure rate of the present invention is 97.5%, and gentamycin matched group is 85.0%.
Claims (3)
1. treat a Chinese medicine for diarrhea of weaned piglets in summer, by the raw material of Chinese medicine medicine of following weight portion, made:
Rhizoma Atractylodis Macrocephalae 6-12 part, Poria 6-12 part, Pericarpium Citri Reticulatae 6-12 part, Cortex Magnoliae Officinalis 6-12 part, Fructus Aurantii Immaturus 6-12 part, Fructus Aurantii 6-12 part, Rhizoma Cyperi 6-12 part, Fructus Crataegi 6-12 part, Massa Medicata Fermentata 6-12 part, Fructus Hordei Germinatus 6-12 part, Rhizoma Pinelliae Preparatum 6-12 part, Semen Lablab Album 6-12 part, Rhizoma Dioscoreae 6-12 part, Semen Nelumbinis 6-12 part, Montmorillonitum 6-12 part, Herba Oxalidis strictae 6-12 part, Herb Polygoni Chinensis 6-12 part, to sitting leaf 6-12 part, Radix Scutellariae 6-12 part, Cortex Ilicis Rotundae 6-12 part, Semen Arecae 6-12 part.
2. the Chinese medicine for the treatment of diarrhea of weaned piglets in summer according to claim 1, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, is made:
9 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts, Poria, 9 parts of Pericarpium Citri Reticulataes, 9 parts of Cortex Magnoliae Officinalis, 9 parts of Fructus Aurantii Immaturuss, 9 parts of Fructus Aurantiis, 9 parts of Rhizoma Cyperis, 9 parts of Fructus Crataegis, 9 parts of Massa Medicata Fermentata, 9 parts, Fructus Hordei Germinatus, 9 parts of Rhizoma Pinelliae Preparatum, 9 parts of Semen Lablab Albums, 9 parts of Rhizoma Dioscoreaes, 9 parts, Semen Nelumbinis, 9 parts of Montmorillonitums, 9 parts of Herba Oxalidis strictaes, 9 parts of Herb Polygoni Chinensiss, to sitting 9 parts, leaf, 9 parts of Radix Scutellariaes, 9 parts of Cortex Ilicis Rotundaes, 9 parts of Semen Arecaes.
3. the preparation method of the Chinese medicine of the treatment diarrhea of weaned piglets in summer described in claim 1 or 2, comprises the steps:
(a) Rhizoma Atractylodis Macrocephalae, Poria, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Fructus Aurantii, Rhizoma Cyperi, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Rhizoma Pinelliae Preparatum, Semen Lablab Album, Rhizoma Dioscoreae, Semen Nelumbinis, Herba Oxalidis strictae, Herb Polygoni Chinensis, to sitting leaf, Radix Scutellariae, Cortex Ilicis Rotundae, Semen Arecae, decoct with water 2 times, the water that adds for the first time 8 times of amounts of drug weight, decoct 1.5 hours, the water that adds for the second time 6 times of amounts of drug weight, decoct 1 hour, collecting decoction, filter, filtrate is condensed into the clear paste that density is 1.15-1.19, clear paste drying under reduced pressure, pulverize, cross 100 mesh sieves, be prepared into extract powder;
(b) Montmorillonitum breaks into fine powder;
(c) the Montmorillonitum fine powder that the extract powder that prepared by step (a) is prepared with step (b) mixes, and adds starch and sucrose, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168612A (en) * | 2015-09-01 | 2015-12-23 | 周自强 | Drug for treating piglet diarrhea, as well as preparation method, detection method and application thereof |
| CN107789394A (en) * | 2017-11-29 | 2018-03-13 | 广州中天康顺生物医药有限公司 | A kind of composition for being used to treat livestock and poultry diarrhea |
| CN107929648A (en) * | 2017-12-30 | 2018-04-20 | 河南省乘风动物保健技术研究所 | It is a kind of suitable for the Traditional Chinese veterinary medicine oral solution with strengthening the spleen and stomach in summer time and preparation method thereof |
-
2013
- 2013-12-30 CN CN201310742727.2A patent/CN103690841A/en active Pending
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| 李水银: "如何选用治疗小儿腹泻的非处方中成药", 《中国中医药报》, 31 August 2001 (2001-08-31) * |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168612A (en) * | 2015-09-01 | 2015-12-23 | 周自强 | Drug for treating piglet diarrhea, as well as preparation method, detection method and application thereof |
| CN107789394A (en) * | 2017-11-29 | 2018-03-13 | 广州中天康顺生物医药有限公司 | A kind of composition for being used to treat livestock and poultry diarrhea |
| CN107789394B (en) * | 2017-11-29 | 2020-10-16 | 广州中天康顺生物医药有限公司 | Composition for treating livestock and poultry diarrhea |
| CN107929648A (en) * | 2017-12-30 | 2018-04-20 | 河南省乘风动物保健技术研究所 | It is a kind of suitable for the Traditional Chinese veterinary medicine oral solution with strengthening the spleen and stomach in summer time and preparation method thereof |
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Application publication date: 20140402 |