CN101878790A - Nutrification flour for diabetics and preparation method thereof - Google Patents
Nutrification flour for diabetics and preparation method thereof Download PDFInfo
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Abstract
The invention discloses nutrification flour for diabetics, which is prepared by mixing 80 to 90 weight percent of wheat flour, 1 to 15 weight percent of wheat bran, 0.3 to 2 weight percent of cassia seed, 0.3 to 2 weight percent of kudzu-vine root, 0.3 to 2 weight percent of bitter gourd powder, 0.3 to 2 weight percent of buck wheat, 0.1 to 1.2 weight percent of konjaku flour, 0.1 to 1.2 weight percent of corn stigma and 3*10<-6> to 8*10<-6> weight percent of selenium. The composite flour of the invention can reduce blood sugar obviously and can improve immunity, prevent hyperlipidemia, hypertension and hyperglycemia, adjust body nutrient balance and keep health.
Description
Technical field
The present invention relates to the grain processing field, be specifically related to a kind of hypoglycemic composite flour that contains multiple medicine-food two-purpose and preparation method thereof.
Background technology
The Haozhou, Anhui be four big medicines one of all, the important Chinese medicine trade market of domestic maximum.Cassia seed wherein, the root of kudzu vine, balsam pear all are the authentic medicinal herbses that picks up from the Haozhou.Nicotinic acid chromium and sodium selenite also are the process safety detection.These Chinese medicines and trace element all have hypoglycemic activity.Sugarfree foods such as diabetic biscuit etc. mostly are to substitute sugar part with xylitol now, and effect is imprecise, and form is single, and mouthfeel is poor, are not suitable for long-term edible.As the pumpkin powder, functional food such as propolis are expensive, are not suitable as staple food and use.Do not come out for the flour of the receptible adjusting blood sugar of people's daily life is also real.
Six the food Co., Ltds in Anhui Province are the larger emphasis of Fuyang City one of the enterprises that invite outside investment, and 1.2 hundred million yuan of company's gross investments are the Co., Ltds to produce, to manage " tailored flour ".The said firm is found in August, 2005, is positioned at the industry park, Taihe County, takes up an area of 130 mu, and overall floorage reaches 73200 squares.Introducing completely the powder craft of joining that state-of-the-art in the world Switzerland cloth is reined in equipment and had advanced level in the world, is the state-of-the-art modernized flour of Anhui Province's equipment processing enterprise.Production building, warehouse for finished product are had in company, and have purchased and joined powder equipment for after-treatment, inspectionization equipment etc.Company can handle more than 20 ten thousand tons of wheats in year, produces 150000 tons in flour per year, and 50,000 tons in wheat bran can be realized about 400,000,000 yuan of annual sales revenue, 2,000 ten thousand yuan of profits taxes.
Enterprise can produce various special wheat flours in line with the principle that green health food is provided for the numerous common people, particularly produces the multiple dimension secondary element of " 7+1 " alimentary paste and WHO popularization promotion and the healthy food of vitamin.
Along with the rising year by year of onset diabetes rate, China diabetic will fully be treated, and spends nearly 500-1000 yuan, and brings huge financial burden to society in every month.Therefore actively probe into the treatment of diabetes method, seek safe and effective procedure treatment diabetes more, improve diabetic's quality of life, become important social issue.Diabetes flour is intervened the prevention and the treatment of diabetes from the dietary structure aspect, for the clinical treatment diabetes provide new thinking and mode, thereby have a extensive future.
Summary of the invention
Purpose of the present invention provides a kind of hypoglycemic composite flour, has reduction blood sugar, improves body immunity, prevents three height, keeps fit and the effect of balance.
Technical scheme of the present invention is as follows:
The special-purpose strengthened nutritious flour of a kind of diabetes, it is characterized in that: its raw material components percentage by weight is:
Wheat flour 80-90%
Wheat bran 1-15%
Cassia seed powder 0.3-2%
Kudzu-vine root powder 0.3-2%
Balsam pear powder 0.3-2%
Buckwheat 0.3-2%
Konjaku flour 0.1-1.2%
Corn stigma 0.1-1.2%
Wherein, contain selenium 300-800ug in every kilogram of whole wheat.
Described whole wheat is characterized in that: the weight ratio of each raw material components is:
Wheat flour 82-86%
Wheat bran 1-15%
Cassia seed powder 0.5-1.2%
Kudzu-vine root powder 0.5-1.2%
Balsam pear powder 0.5-1.2%
Buckwheat 0.2-0.8%
Konjaku flour 0.2-0.8%
Corn stigma 0.2-0.6%
Wherein, contain selenium 500-700ug in every kilogram of whole wheat.
The preparation method of whole wheat may further comprise the steps:
(1) takes by weighing wheat flour and various batching by formula rate;
(1) place three-dimensional motion mixer to mix various batchings by formula rate;
(2) with infrared ray the batching that step (1) mixes is sterilized;
(3) the mix sampling inspection after will sterilizing;
(4) mix that is up to the standards is joined with in the wheat flour that weighs up, fully mixed at three-dimensional mixer
Close evenly, and finished product;
(5) with finished product packing, warehouse-in.
The root of kudzu vine among the present invention: nature and flavor are cool in nature, and it is sweet, hot to distinguish the flavor of.Function cures mainly to induce sweat brings down a fever, and promotes the production of body fluid, and promoting eruption rises positive antidiarrheal.Be used for fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery, have loose bowels.Rise positive expelling pathogenic factors from muscles and skin, promoting eruption antidiarrheal, relieving restlessness is quenched the thirst.Root of kudzu vine chemical composition contains multiple flavones ingredient, and main active is big legumin, daidzin (daidzin), Puerarin, Puerarin-7-xyloside etc.The root of kudzu vine vegetarian diet root of kudzu vine promotes the production of body fluid to quench thirst.Reduce the active ingredient of blood sugar treatment diabetes, give alloxan hyperglycaemia mouse stomach with Puerarin.Blood sugar is reduced.Effect can be kept 24 hours, and can improve sugar tolerance.Certain antiadrenergic drug liter sugar is acted on arranged.Puerarin has inhibitory action to rat crystal aldehyde ketone reductase.The control diabetic complication there is positive effect.The root of kudzu vine and related drugs compatibility treatment diabetes effect are remarkable.Compendium of Material Medica record: the root of kudzu vine, Gan Xinping.Cure mainly, quench one's thirst.High fever of the body, vomiting.All numbness.Play cloudy gas, separate all poison.
Balsam pear is our often edible a kind of vegetables among the present invention, and it belongs to Curcurbitaceae balsam pear plant, the nature and flavor bitter cold, have refrigerant analgesic, nourish effects such as strong.But because its flavor is very bitter, many northerners do not like edible balsam pear.Be rich in the balsam pear in fact and have the bioactive ingredients that reduces blood sugar, regulatory enzyme activity, effect such as antitumor and antiviral, scientist has purified and the composition that confirms has momordica lectin element, Charantin, ribosome inactivating protein, the plain glycosides of Pu's melon, carrot, sterol, MAP 30 albumen, P albumen etc. at present.Health-care effect with hypoglycemic, antitumor and anti-virus aspect.Discover that balsam pear not only can obviously reduce blood sugar level after the fasting, but also can obviously reduce the level of cholesterol and triglycerides in the liver.Further research is observed, and the hypoglycemic effect difference of balsam pear different parts extract is also different to the blood sugar decreasing effect of insulin-dependent and Non-Insulin Dependent Diabetes Mellitus.Wherein the pericarp extract hypoglycemic effect of balsam pear is more obvious, can make postprandial blood sugar descend 36%.The extract that balsam pear seed, full fruit, full fruit remove Escin to fasting and after the meal the blood sugar level of insulin-dependent diabetes mellitus rat all do not have obvious influence, and Bitter Melon Juice can obviously reduce blood sugar level after the fasting of Non-Insulin Dependent Diabetes Mellitus rat, and make its postprandial blood sugar content reduce by 50%, illustrate that Bitter Melon Juice has than the obvious functions of blood sugar effect.Research also shows, the acetone extract of the full fruit of oral balsam pear 15～30 days, blood sugar and serum cholesterol can be reduced to normal level, even cut out Bitter Melon P.E 15 days afterwards, blood sugar level does not raise yet, and illustrates that the blood sugar decreasing effect of Bitter Melon P.E is more stable lasting.Balsam pear fruit extract and hypoglycemic medicine results of comparative experiment commonly used show, the every kg body weight of drug-induced diabetes rat gives the balsam pear fruit extract of 500 milligrams of dosage, raised path between farm fields makes the smart level of 1 hour after the meal blood reduce by 10%～15%, effect is equivalent to give 25%～30% of same agent scape orinase hypoglycemic effect, perhaps is equivalent to whenever do the gram body weight and gives
Cassia seed among the present invention claims again " Cassia occidentalis ", and is sweet, bitter, salty, is slightly cold.Return liver, large intestine channel.Removing heat to brighten vision is arranged, the step-down of dispeling the wind, function of relaxing bowel.Cassia seed can suppress the serum cholesterol rising and arteriosclerosis plaque forms, and cooperates chrysanthemum that certain hypotensive effect is arranged. and have certain hypoglycemic activity.Guangzhou army " Chinese herbal medicine handbook commonly used: clear liver and improve vision sharp water defaecation.Control hepatitis, cirrhotic ascites, hypertension, infantile malnutrition, yctalopia, wind-heat ophthalmodynia, habitual constipation
Contain abundant lysine composition among the present invention in the buck wheat protein matter, trace element such as iron, manganese, zinc is abundanter than general cereal, and contains and enrich dietary fiber, is general 10 times of refining rice.So buckwheat has good nutrition health-care functions.Buckwheat contains abundant vitamin E and soluble dietary fiber, also contains nicotinic acid and rutin (rutin) simultaneously, and rutin has the effect that reduces human body blood fat and cholesterol, softening blood vessel, vision protection and prevention of brain angiorrbagia.The nicotinic acid composition that it contains can promote the metabolism of body, strengthens detoxification ability, also has the effect of little blood vessel of expansion and reduction blood cholesterol levels.Buckwheat contains abundant magnesium, can promote human fiber's protein dissolution, distends the blood vessels, and suppresses the formation of sludged blood, has the effect of embolism resistance, also helps reducing serum cholesterol.
The glutelin content of buckwheat is very low, and main protein is globulin.Lysine content height in the contained essential amino acid of buckwheat and the content of methionine is low, amino acid pattern can with main cereal (lysine content as wheat, corn, rice is lower) complementation.
The carbohydrate of buckwheat mainly is a starch.Because particle is more tiny, thus compare with other cereals, have easily boil, digestion easily, easy machining characteristics.Buckwheat contains rich dietary fiber, and its content is 10 times of generally refining rice; Trace elements such as the iron that buckwheat contains, manganese, zinc are also abundant than general cereal.That some flavone component in the buckwheat also has is antibiotic, anti-inflammatory, cough-relieving, the effect of relievining asthma, eliminating the phlegm.Therefore, buckwheat also has the laudatory title of " anti-inflammatory grain ".These compositions also have the effect that reduces blood sugar in addition.Motherland's medical science thinks, the buckwheat nature and flavor are sweet flat, strengthening the spleen and replenishing qi arranged, the merit of whet the appetite wide intestines, relieving dyspepsia
Wheat bran provides wheat edible fiber among the present invention: control high fat of blood, diabetes.Dietary fiber and lipid, cholate is bonded together, and discharges by ight soil, has reduced triglycerides and cholesterol level in the blood, and dietary fiber can postpone the absorption of glucose.But and the appearance of postponement digestible saccharide in small intestine.Dietary fiber can alleviate the function burden of insulin cell.Dietary fiber can also alleviate the function burden of insulin cell.Dietary fiber can also make blood sugar be in stable state.Dwindle the variation amplitude of blood sugar concentration, diabetes are had stabilization.Someone carries out investigation statistics once to the dietary fiber intake with the incidence of disease.Often lack dietary fiber.Can cause gastrointestinal disease, angiocardiopathy, metabolism is sick.
Buckwheat among the present invention: buckwheat contains rich dietary fiber, and its content is 10 times of generally refining rice; Trace elements such as the iron that buckwheat contains, manganese, zinc are also abundant than general cereal.That some flavone component in the buckwheat also has is antibiotic, anti-inflammatory, cough-relieving, the effect of relievining asthma, eliminating the phlegm.Therefore, buckwheat also has the laudatory title of " anti-inflammatory grain ".These compositions also have the effect that reduces blood sugar in addition.Motherland's medical science thinks, the buckwheat nature and flavor are sweet flat, strengthening the spleen and replenishing qi arranged, the effect of whet the appetite wide intestines, relieving dyspepsia.The volunteer eats 4 weeks of buckwheat, the ratio of highdensity lipoprotein-cholesterol/T-CHOL is obviously increased, VLDL-cholesterol, VLDL-three acid glycerol, low-density lipoprotein-triacylglycerol and HDL-triacylglycerol obviously reduce, and blood sugar is reduced, the tolerance of oral glucose improves.Raise the rat in 4 weeks with the feed that contains buckwheat, the tolerance of glucose also improved, and behind glucose load 1h, the utilization of insulin speeds up.The high fat diet rabbit is taken buckwheat extract after 12 weeks, can slightly reduce MDA in the blood (MDA) concentration, but showing the content that increases AFR in the liver and following in the blood reduction of cholesterol and triacylglycerol concentration in the beta lipoprotein level and liver, testosterone phenylacetate also increases simultaneously in the blood, and effect is better than rutin far away
Konjaku among the present invention, perennial Araeceae herbaceous plant, slightly poisonous. of many uses.Konjaku be find at present, unique industrial crops that glucomannans can be provided in a large number, will constantly be developed in the using value of konjaku aspect the food medicine.Konjaku is subjected to people's popular welcome because of having very high edibility, its Main Ingredients and Appearance is a glucomannans, it not only contains 10 several amino acids and the various trace elements of needed by human body, have more characteristics such as low albumen, low fat, high fiber, water imbibition are strong, expansion rate height, the medicinal efficacy aspect has multiple curative effects such as reducing blood lipid, hypoglycemic, hypotensive, toxin expelling, fat-reducing, beauty treatment, health care, defaecation ease constipation stomach.
Utilizing the present invention is a kind of hypoglycemic Chinese medicine of multiple medicine-food two-purpose and composite flour of trace element of containing.Solved diabetic's diet problem, the diabetic is no longer worried for diet.Add balsam pear, the root of kudzu vine, cassia seed konjaku etc. in the long patent flour and have relevant trace elements such as the traditional Chinese medicine ingredients of certain blood sugar reducing function and selenium, wheat bran, wheat embryo in addition, a kind of novel flour specially for diabetic that dietary fiber etc. are combined into, this wheat flour specially not only can help the overweight people to reduce the energy absorption, keep normal body weight, also can alleviate the insulin burden, blood sugar, blood fat be reached or, and prevent or the generation and the development of complication such as retarding cardiovascular near normal value.
This special-purpose strengthened nutritious flour has following characteristics:
1, the heat energy nutrient content is accurately stablized, and can significantly improve the matching degree and the security of diet and glucose-lowering treatment method;
2, the hypoglycemic proportioning of science makes things convenient for the diabetic to use dietetic treatment to Blood glucose control;
3, exclusive protein and dietary fiber matching design more helps reducing postprandial blood sugar;
4, as a kind of staple food, mouthfeel is good, and various informativeization (noodles, instant noodles, steamed bun, dumpling etc.) is convenient to the long-term control diet;
5, expense is lower than the diabetes special food, is no more than 20 yuan than the increase of the long patent flour moon, can be accepted by ordinary populace.
The specific embodiment;
The special-purpose strengthened nutritious flour of a kind of diabetes, it is characterized in that: its raw material components percentage by weight is:
Wheat flour 80-90%
Wheat bran 1-15%
Cassia seed powder 0.3-2%
Kudzu-vine root powder 0.3-2%
Balsam pear powder 0.3-2%
Buckwheat 0.3-2%
Konjaku flour 0.1-1.2%
Corn stigma 0.1-1.2%
Wherein, contain selenium 300-800ug in every kilogram of whole wheat.
Described whole wheat is characterized in that: the weight ratio of each raw material components is:
Wheat flour 82-86%
Wheat bran 1-15%
Cassia seed powder 0.5-1.2%
Kudzu-vine root powder 0.5-1.2%
Balsam pear powder 0.5-1.2%
Buckwheat 0.2-0.8%
Konjaku flour 0.2-0.8%
Corn stigma 0.2-0.6%
Wherein, contain selenium 500-700ug in every kilogram of whole wheat.
The preparation method of described whole wheat may further comprise the steps:
(1) takes by weighing wheat flour and various batching by formula rate;
(1) place three-dimensional motion mixer to mix various batchings by formula rate;
(2) with infrared ray the batching that step (1) mixes is sterilized;
(3) the mix sampling inspection after will sterilizing;
(4) mix that is up to the standards is joined with in the wheat flour that weighs up, fully mixes at three-dimensional mixer, and finished product;
(5) with finished product packing, warehouse-in.
Illustrate whole wheat of the present invention with pharmacological testing below and have the curative effect effect that reduces the blood sugar effect:
1,18 monthly age of animal used as test Wistar male rat is 200, body weight 200 ± 20 grams, and effluent south medical university Experimental Animal Center provides, and raises a week with basal feed adaptability earlier before the modeling.Basal feed: protein accounts for 23%, and carbohydrate accounts for 53%, and fat accounts for 5%; Available from Medical University Of Anhui's Animal House.
2, the grouping of rat; 200 rats are divided into 4 groups at random, that is: blank group, model group, experimental group, control group, 50 every group.
3, animal model is made and is raised
12/12 hour light and shade cycle, freely to ingest, drink water, blank group continues to feed with basal feed to experiment and finishes.Model group and treatment group are fed with the high heat feed, around amounting to.(be dissolved in the 0.1mmol/L citrate buffer solution, pH4.4) by injection Streptozotocin (STZ) in the dosage disposable celiac of 20mg/kg body weight then.The standard of modeling success is: fasting was pressed the 2g/kg body weight in 12 hours and is irritated hello 20%D-glucose solution after 72 hours, did the experiment of oral glucose tolerance, and blood sugar was respectively greater than 7.0mmol/L and 11.1mmol/L in 0 and 120 minute.
4, medication: grouping and administration situation are as follows:
Blank group: freely drink water, ingest.
Model group: after the modeling success, freely drink water, ingest.
Experimental group: after the modeling success, be that 810mg/kg feeds with flour specially for diabetic of the present invention by 9 times of clinical adult's dosage every day.Control group: after the modeling success, be that 810mg/kg feeds with common edible flour by 9 times of clinical adult's dosage every day.Experimental studies results such as table 1
The table 1 pair glycometabolic influence of STZ-DM rat (
N=8)
As can be seen from Table 1, the modeling control group is compared with normal group, and blood glucose value obviously reduces.
Claims (3)
1. the special-purpose strengthened nutritious flour of diabetes, it is characterized in that: its raw material components percentage by weight is:
Wheat flour 80-90%
Wheat bran 1-15%
Cassia seed powder 0.3-2%
Kudzu-vine root powder 0.3-2%
Balsam pear powder 0.3-2%
Buckwheat 0.3-2%
Konjaku flour 0.1-1.2%
Corn stigma 0.1-1.2%
Wherein, contain selenium 300-800ug in every kilogram of whole wheat.
2. whole wheat according to claim 1 is characterized in that: the weight ratio of each raw material components is:
Wheat flour 82-86%
Wheat bran 1-15%
Cassia seed powder 0.5-1.2%
Kudzu-vine root powder 0.5-1.2%
Balsam pear powder 0.5-1.2%
Buckwheat 0.2-0.8%
Konjaku flour 0.2-0.8%
Corn stigma 0.2-0.6%
Wherein, contain selenium 500-700ug in every kilogram of whole wheat.
3. the preparation method of claim 1 or 2 described whole wheats is characterized in that may further comprise the steps:
(1) takes by weighing wheat flour and various batching by formula rate;
(1) place three-dimensional motion mixer to mix various batchings by formula rate;
(2) with infrared ray the batching that step (1) mixes is sterilized;
(3) the mix sampling inspection after will sterilizing;
(4) mix that is up to the standards is joined with in the wheat flour that weighs up, fully mixes at three-dimensional mixer, and finished product;
(5) with finished product packing, warehouse-in.
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