CN101485825A - Chinese medicine capsule for treating diabetes - Google Patents
Chinese medicine capsule for treating diabetes Download PDFInfo
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- CN101485825A CN101485825A CN 200810056298 CN200810056298A CN101485825A CN 101485825 A CN101485825 A CN 101485825A CN 200810056298 CN200810056298 CN 200810056298 CN 200810056298 A CN200810056298 A CN 200810056298A CN 101485825 A CN101485825 A CN 101485825A
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Abstract
The invention discloses a traditional Chinese medicine capsule for treating diabetes, which is prepared by extracting traditional Chinese medicinal materials such as cinnamon, radix aconite lateralis preparata, root of rehmannia, raw radix astragali, rhizoma atractylodis, figwort, salvia miltiorrhiza, kudzuvine root, dwarf lilyturf turber, tuckahoe, dogwood fruit, Chinese yam, cortex moutan and the like. The capsule has the efficacies of tonifying Qi, strengthening the spleen, tonifying the kidney, promoting the production of body fluid to quench thirst, reducing blood sugar, and healing three eliminating masses. Compared with the prior traditional Chinese medicine, the traditional Chinese medicine capsule has the advantages of smooth and beautiful appearance, can conceal unpleasant odor of the medicine, and is convenient to take; compared with tablets and pills, the capsule has quick disintegration in the gastrointestinal tract, and quicker absorption and effect; and the medicine is filled in the capsule and isolated from rays, air and moisture, and increases stability.
Description
Technical field
The invention belongs to field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese medicinal capsule agent for the treatment of diabetes, and the preparation method of this capsule.
Technical background
Along with the progress of society and the change of life style, diabetes have become commonly encountered diseases, the frequently-occurring disease of the many countries in the whole world, serious threat human health, its mortality rate have leapt to the 3rd after tumor, the cardiovascular diseases, and sickness rate presents continuous growth trend in the world.According to World Health Organization (WHO) prediction, world's diabetics number to 2025 year will break through 3.0 hundred million.
The effect of tcm product blood sugar lowering, the internal organs of adjusting, slow blood sugar reducing function are arranged, main effect is to distinguish that disease executing control, medication to the ill just, add and subtract with disease, play the effect for the treatment of both the principal and secondary aspects of a disease, adopt treatment by Chinese herbs glycosuria condition of disease to reach the effect of nursing one's health each internal organs organ dysfunction and raising patient autoimmunity from inside of human body.The internal organs functional recovery of human body, blood glucose has also just descended naturally, simultaneously the body constitution of health also has in various degree raising and improvement, thus fundamentally treatment (being not to cure) diabetes, the patient is got well.
The present invention is the capsule of Chinese medicine, plays advantage than Chinese medicine to be:
(1) outward appearance is bright and clean, and is attractive in appearance, and can cover the bad smell of medicine, is convenient to take;
(2) compare with tablet, pill, in gastrointestinal tract disintegrate fast, absorb, produce effects is also very fast;
(3) medicine is loaded in the capsule, isolates with light, air and dampness, and stability increases.
Summary of the invention
One of the object of the invention is to provide a kind of Chinese medicinal capsule agent for the treatment of diabetes.
Two of the object of the invention is to provide the preparation method of this capsule.
A kind of Chinese medicinal capsule agent for the treatment of diabetes provided by the invention comprises the following weight proportion raw material:
1, prescription (part is a unit of weight)
20-60 parts in 20-60 parts of Radix Rehmanniae of 20-60 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
20-60 parts of 20-60 portions of Radix Scrophulariaes of 20-60 parts of Rhizoma Atractylodis of Radix Astragali
15-40 parts of 20-60 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 20-60 parts of Radix Ophiopogonis
15-40 parts of 15-40 parts of Rhizoma Dioscoreaes of 20-60 parts of Fructus Corni of Poria
15-40 parts of pools of Cortex Moutan are let out 15-40 parts
2, preparation technology:
(1) get Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Astragali, Rhizoma Atractylodis, Fructus Corni, Rhizoma Dioscoreae, Cortex Moutan, pool and let out and add water and decoct 2-3 times for 8-12 times, each 2-3 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.45 (50 ℃), and is standby;
(2) get Radix Scrophulariae, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Ophiopogonis, the clean coarse powder that is ground into of Poria medical material again, add ethanol (50%-80%) reflux 2-3 time, each 2-3 hours, merge extractive liquid,, decompression recycling ethanol also is concentrated into the clear paste that relative density is 1.15-1.25 (50 ℃), cold preservation 12-24 hours, standby;
(3) thick paste such as Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Scrophulariae, Radix Salviae Miltiorrhizae clear paste are merged, stirring and being evaporated to relative density is 1.25-1.30 clear paste, and vacuum drying is pulverized, the extract dried cream powder, incapsulate, promptly.
Adopt said medicine combination and preparation method thereof, the present invention can treat that the deficiency of YIN is scorching, the diabetes of three types of deficiency of both YIN and YANG, blood stasis due to qi deficiency, has QI invigorating, spleen invigorating, the kidney invigorating, promoting the production of body fluid to quench thirst, blood sugar lowering, the effect of three types of diabetes more.
The test example:
(1) acute toxicity test data
Give mouse stomach (ig) capsule 's content 22.5g of the present invention, 15.0g/kg, mice no abnormality seen reaction in seven days.After pressing maximum dosage-feeding (crude drug 654g/kg) gastric infusion to mice, three times on the one, do not see the overt toxicity reaction, and no dead mouse in the week.
(2) long term toxicity test data
Get capsule 's content of the present invention, high, medium and low three dosage groups are set, give mouse stomach (ig) administration respectively, test administration 3,6 months and after 2 weeks of drug withdrawal, test the hair luster of rat, activity, feed and drinking-water situation are all normal, the no abnormality seen phenomenon, and do not see that internal organs are unusual, each dosage group organ coefficient and matched group no significant difference do not have obvious influence to physiochemical indice, biochemical indicator.Result of the test shows that capsule long-term prescription of the present invention does not have the overt toxicity effect.
Embodiment 1
1, prescription (part is a unit of weight)
20 parts in 20 parts of Radix Rehmanniae of 20 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
20 parts of 200 portions of Radix Scrophulariaes of 20 parts of Rhizoma Atractylodis of Radix Astragali
15 parts of 20 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 20 parts of Radix Ophiopogonis
15 parts of 15 portions of Rhizoma Dioscoreaes of 20 parts of Fructus Corni of Poria
15 parts of pools of Cortex Moutan are let out 15 parts
2, preparation technology:
(1) get Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Astragali, Rhizoma Atractylodis, Fructus Corni, Rhizoma Dioscoreae, Cortex Moutan, pool let out add 12 times in water and decoct 2-inferior, 3 hours for the first time, 2 hours for the second time, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.45 (50 ℃), and is standby;
(2) get Radix Scrophulariae, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Ophiopogonis, the clean coarse powder that is ground into of Poria medical material again, add ethanol (80%) reflux 2 times, 2 hours for the first time, 3 hours for the second time, merge extractive liquid,, decompression recycling ethanol also is concentrated into the clear paste that relative density is 1.15-1.25 (50 ℃), and cold preservation 12-24 hours is standby;
(3) thick paste such as Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Scrophulariae, Radix Salviae Miltiorrhizae clear paste are merged, stirring and being evaporated to relative density is 1.25-1.30 clear paste, and vacuum drying is pulverized, the extract dried cream powder, incapsulate, promptly.
Embodiment 2
1, prescription (part is a unit of weight)
60 parts in 60 parts of Radix Rehmanniae of 60 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
60 parts of 60 portions of Radix Scrophulariaes of 60 parts of Rhizoma Atractylodis of Radix Astragali
40 parts of 60 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 60 parts of Radix Ophiopogonis
40 parts of 40 portions of Rhizoma Dioscoreaes of 60 parts of Fructus Corni of Poria
40 parts of pools of Cortex Moutan are let out 40 parts
2, preparation technology:
(1) get Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Astragali, Rhizoma Atractylodis, Fructus Corni, Rhizoma Dioscoreae, Cortex Moutan, pool and let out and add water and decoct 3 times for 8 times, preceding twice each 3 hours, 2 hours for the third time, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.45 (50 ℃), and is standby;
(2) get Radix Scrophulariae, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Ophiopogonis, the clean coarse powder that is ground into of Poria medical material again, add ethanol (60%) reflux 2 times, each 2 hours, merge extractive liquid,, decompression recycling ethanol also is concentrated into the clear paste that relative density is 1.15-1.25 (50 ℃), and cold preservation 12-24 hours is standby;
(3) thick paste such as Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Scrophulariae, Radix Salviae Miltiorrhizae clear paste are merged, stirring and being evaporated to relative density is 1.25-1.30 clear paste, and vacuum drying is pulverized, the extract dried cream powder, incapsulate, promptly.
Embodiment 3
1, prescription (part is a unit of weight)
40 parts in 40 parts of Radix Rehmanniae of 40 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
40 parts of 40 portions of Radix Scrophulariaes of 40 parts of Rhizoma Atractylodis of Radix Astragali
15-40 parts of 40 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 40 parts of Radix Ophiopogonis
30 parts of 30 portions of Rhizoma Dioscoreaes of 40 parts of Fructus Corni of Poria
30 parts of pools of Cortex Moutan are let out 30 parts
2, preparation technology:
(1) get Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Astragali, Rhizoma Atractylodis, Fructus Corni, Rhizoma Dioscoreae, Cortex Moutan, pool and let out and add water and decoct 3 times for 10 times, preceding twice each 2 hours, three times 3 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.45 (50 ℃), and is standby;
(2) get Radix Scrophulariae, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Ophiopogonis, the clean coarse powder that is ground into of Poria medical material again, add ethanol (70%) reflux 2 times, each 3 hours, merge extractive liquid,, decompression recycling ethanol also is concentrated into the clear paste that relative density is 1.15-1.25 (50 ℃), and cold preservation 12-24 hours is standby;
(3) thick paste such as Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Scrophulariae, Radix Salviae Miltiorrhizae clear paste are merged, stirring and being evaporated to relative density is 1.25-1.30 clear paste, and vacuum drying is pulverized, the extract dried cream powder, incapsulate, promptly.
Claims (3)
1, a kind of Chinese medicinal capsule agent for the treatment of diabetes is characterized in that this Chinese medicinal capsule agent is to be made by the raw material of following weight:
20-60 parts in 20-60 parts of Radix Rehmanniae of 20-60 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
20-60 parts of 20-60 portions of Radix Scrophulariaes of 20-60 parts of Rhizoma Atractylodis of Radix Astragali
15-40 parts of 20-60 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 20-60 parts of Radix Ophiopogonis
15-40 parts of 15-40 parts of Rhizoma Dioscoreaes of 20-60 parts of Fructus Corni of Poria
15-40 parts of pools of Cortex Moutan are let out 15-40 parts.
2, a kind of Chinese medicinal capsule agent for the treatment of diabetes as claimed in claim 1 is characterized in that this Chinese medicinal capsule agent is to be made by the raw material of following weight:
40 parts in 40 parts of Radix Rehmanniae of 40 parts of Radix Aconiti Lateralis Preparatas of Cortex Cinnamomi
40 parts of 40 portions of Radix Scrophulariaes of 40 parts of Rhizoma Atractylodis of Radix Astragali
15-40 parts of 40 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae 40 parts of Radix Ophiopogonis
30 parts of 30 portions of Rhizoma Dioscoreaes of 40 parts of Fructus Corni of Poria
30 parts of pools of Cortex Moutan are let out 30 parts.
3, a kind of Chinese medicinal capsule agent for the treatment of diabetes as claimed in claim 1 is characterized in that this Chinese medicinal capsule agent preparation technology is:
(1) get Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Astragali, Rhizoma Atractylodis, Fructus Corni, Rhizoma Dioscoreae, Cortex Moutan, pool and let out and add water and decoct 2-3 times for 8-12 times, each 2-3 hours, filter, merging filtrate is evaporated to the thick paste of relative density 1.30～1.45 (50 ℃), and is standby;
(2) get Radix Scrophulariae, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Ophiopogonis, the clean coarse powder that is ground into of Poria medical material again, add ethanol (50%-80%) reflux 2-3 time, each 2-3 hours, merge extractive liquid,, decompression recycling ethanol also is concentrated into the clear paste that relative density is 1.15-1.25 (50 ℃), cold preservation 12-24 hours, standby;
(3) thick paste such as Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Scrophulariae, Radix Salviae Miltiorrhizae clear paste are merged, stirring and being evaporated to relative density is 1.25-1.30 clear paste, and vacuum drying is pulverized, the extract dried cream powder, incapsulate, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810056298 CN101485825A (en) | 2008-01-16 | 2008-01-16 | Chinese medicine capsule for treating diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810056298 CN101485825A (en) | 2008-01-16 | 2008-01-16 | Chinese medicine capsule for treating diabetes |
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| CN101485825A true CN101485825A (en) | 2009-07-22 |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773624A (en) * | 2010-02-09 | 2010-07-14 | 陈秋生 | Traditional Chinese medicine composition for curing diabetes and preparation method thereof |
| CN101703686B (en) * | 2009-11-16 | 2011-03-23 | 齐艳华 | Chinese medicinal composition for treating diabetes |
| CN104666654A (en) * | 2015-03-15 | 2015-06-03 | 陈彬 | Traditional Chinese medicine composition for treating yin and yang deficiency diabetes and preparation method of traditional Chinese medicine composition |
| US9089577B1 (en) * | 2014-07-28 | 2015-07-28 | Nanzheng Cheng | Water extracts of cinnamon and Radix Astragali |
| CN104906251A (en) * | 2015-07-10 | 2015-09-16 | 江苏省中医院 | Traditional Chinese medicine compound combination with diabetes treating effect and preparation method and application thereof |
| CN105194342A (en) * | 2015-10-26 | 2015-12-30 | 冯天宁 | Traditional Chinese medicinal composition for treating diabetes |
| US9877992B2 (en) | 2014-07-28 | 2018-01-30 | Nanzheng Cheng | Water extracts of cinnamon and Radix Astragali |
| CN108853130A (en) * | 2018-09-30 | 2018-11-23 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and its preparation method and application comprising Catalpol |
| CN109010299A (en) * | 2018-09-30 | 2018-12-18 | 北京济全生物科技有限公司 | A kind of sustained release hypoglycemic medicine composition and its preparation method and application |
| CN114533815A (en) * | 2020-11-24 | 2022-05-27 | 王红卫 | Oral medicine for treating type II diabetes |
-
2008
- 2008-01-16 CN CN 200810056298 patent/CN101485825A/en active Pending
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101703686B (en) * | 2009-11-16 | 2011-03-23 | 齐艳华 | Chinese medicinal composition for treating diabetes |
| CN101773624A (en) * | 2010-02-09 | 2010-07-14 | 陈秋生 | Traditional Chinese medicine composition for curing diabetes and preparation method thereof |
| US9089577B1 (en) * | 2014-07-28 | 2015-07-28 | Nanzheng Cheng | Water extracts of cinnamon and Radix Astragali |
| US10543244B2 (en) | 2014-07-28 | 2020-01-28 | Nanzheng Cheng | Water extracts of cinnamon and radix astragali |
| US9877992B2 (en) | 2014-07-28 | 2018-01-30 | Nanzheng Cheng | Water extracts of cinnamon and Radix Astragali |
| CN104666654A (en) * | 2015-03-15 | 2015-06-03 | 陈彬 | Traditional Chinese medicine composition for treating yin and yang deficiency diabetes and preparation method of traditional Chinese medicine composition |
| CN104906251B (en) * | 2015-07-10 | 2017-12-08 | 江苏省中医院 | A kind of Traditional Chinese medicine compound composition with treatment diabetes effect and preparation method and application |
| CN104906251A (en) * | 2015-07-10 | 2015-09-16 | 江苏省中医院 | Traditional Chinese medicine compound combination with diabetes treating effect and preparation method and application thereof |
| CN105194342A (en) * | 2015-10-26 | 2015-12-30 | 冯天宁 | Traditional Chinese medicinal composition for treating diabetes |
| CN105194342B (en) * | 2015-10-26 | 2018-10-23 | 冯天宁 | It is a kind of to treat Chinese medicine for treating diabetes composition |
| CN108853130A (en) * | 2018-09-30 | 2018-11-23 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and its preparation method and application comprising Catalpol |
| CN109010299A (en) * | 2018-09-30 | 2018-12-18 | 北京济全生物科技有限公司 | A kind of sustained release hypoglycemic medicine composition and its preparation method and application |
| CN108853130B (en) * | 2018-09-30 | 2019-08-13 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and preparation method thereof |
| CN114533815A (en) * | 2020-11-24 | 2022-05-27 | 王红卫 | Oral medicine for treating type II diabetes |
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Open date: 20090722 |