CN103182008A - Preparation method for traditional Chinese medicine used for stabilizing and reducing blood pressure - Google Patents

Abstract

The invention provides a preparation method for a traditional Chinese medicine used for stabilizing and reducing blood pressure, which belongs to the field of pharmaceutical technology. The traditional Chinese medicine is mainly prepared from the following components by weight: 6 to 30 g of apocynum venetum, 5 to 20 g of Chinese angelica, 10 to 20 g of fleece-flower root, 10 to 40 g of barbary wolfberry fruit, 5 to 20 g of eucommia, 5 to 10 g of ginseng, 10 to 15 g of red sage root, 15 to 20 g of hawthorn fruit, 20 to 30 g of milkvetch root, 40 go 50 g of root of large-flowered skullcap, 40 to 50 g of Chinese magnoliavine, 30 to 40 g of safflower, 40 to 60 g of gynostemma pentaphylla, 35 to 45 g of cassia seed, 40 to 50 g of root of kudzu vine, 40 to 50 g of oriental waterplantain rhizome, 30 to 40 g of chrysanthemum and auxiliary materials consisting of 1000 to 3000 g of liquor and 1200 to 3000 g of distilled water.

Description

A kind of voltage stabilizing and Chinese hypotensor manufacture method

Technical fieldThe present invention relates to A kind of voltage stabilizing and Chinese hypotensor manufacture method, belong to the pharmaceutical technology field.

Background technologyHypertension refers under quiescent condition systolic arterial pressure and/or diastolic pressure not in normal range, organ dysfunction or organic changes such as unrest and the heart, brain, kidney and retina.Clinically a lot of hypertensive patients particularly obese type is often with diabetes, and diabetes are also more with hypertension.

Hypertension be a kind of be feature with the arterial pressure rising, can be functional with heart, blood vessel, brain and kidney and other organs or the systemic disease of organic change, it has the branch of essential hypertension and secondary hypertension.The reason of hypertension incidence is a lot, can be divided into two aspects of h and E.Chinese medicine thinks that hypertension is because the result that the body imbalance between YIN and YANG produces.The deficiency of YIN is this, yang hyperactivity is mark; pathological changes is relevant with the five internal organs, but writes in the complete works of book of refined auspicious Chinese medicine: the main heart, liver, the kidney of relating to is being designated as liver; be kidney originally; clinical manifestation is cardinal symptom with the hepatic and renal YIN deficiency or excessive rising of liver-YANG, decreasing in preceding with the moon, yang hyperactivity in after be main feature; arrived the course of disease later stage, developed into deficiency of both YIN and YANG.So at human five internal organs's six internal organs corresponding projection is arranged on foot, foot is the starting point of Three Yin Channels of Foot, is again the terminating point of the three yang channels of foots, and more than 60 acupuncture point just arranged below the ankle joint.The conditioning viscera function is recovered equilibrium between yin and yang, is the hypertensive basic principle of traditional Chinese medical herbal treatment.Hypertension, the traditional Chinese medical science is divided into three types with it, i.e. excessive rising of liver-YANG, the hepatic and renal YIN deficiency, QI and blood deficiency.The medicine major part for the treatment of high blood pressure disease of the prior art is the dependent drug of curing the symptoms, not the disease.When taking, the kind that the patient needs often to change medicine reaches the drug-fast problem that solves.When most medicine is taken more than 3 years the patient, because the negative interaction of medicine brings new pathological changes can for each internal organs of human body.

Hypertension refer to body circulation systolic pressure and (or) diastolic pressure continue to raise be that main clinical manifestation is accompanied or without the syndrome of multiple cardiovascular risk factors, abbreviated hypertension usually as.Be divided into essential hypertension (95%) and secondary hypertension (＜5%), hypertension is the important cause of disease and the risk factor of the multiple heart, cerebrovascular disease, influence important organ, after one's own heart, the structure of brain, kidney and function, the nonfunction that finally causes these organs is still one of cardiovascular disease main causes of death so far.

Summary of the inventionThe objective of the invention is the deficiency at above-mentioned technology, and provide a kind for the treatment of both the principal and secondary aspects of a disease to people, can nourishing the liver and kidney, blood pressure lowering, voltage stabilizing Chinese medicine and the manufacture method of suppressing the hyperactive liver blood pressure lowering, heart tonifying.For achieving the above object, the present invention adopts following technical proposals: A kind of blood pressure lowering and voltage stabilizing Chinese medicine and manufacture methodMainly

Also made by weight ratio by following component:

Herba Apocyni veneti 6-30g

Radix Angelicae Sinensis 5-20g

Radix Polygoni Multiflori 10-2 0g

Fructus Lycii 10-4 0g

Cortex Eucommiae 5-2 0g

Radix Ginseng 5-10 g

Radix Salviae Miltiorrhizae 10-15 g

Fructus Crataegi 15-20 g

Radix Astragali 20-30 g

Radix Scutellariae 40-50g

Fructus Schisandrae Chinensis 40-50g

Flos Carthami 30-40g

Herb Gynostemmae Pentaphylli 40-60g

Semen Cassiae 35-45g

Radix Puerariae 40-50g

Rhizoma Alismatis 40-50g

Flos Chrysanthemi 30-40g

Adjuvant:

Chinese liquor l000-3000g

Distilled water 1200-3000g

Concrete manufacture method is:

(1) makes Chinese liquor earlier, Chinese liquor is contained in the container;

(2) said medicine is pulverized, and packed into after with the medicine mixing by said ratio and to contain in the container of wine;

(3) with container heating, steaming and decocting, boiled 30 minutes;

(4) well-done medicine filters, the filtering medicinal residues;

(5) distilled water is mixed with medicinal liquid, make blood pressure lowering medicated wine.As to make tablet, pill, and the consumption of its adjuvant of injection adopt lower limit, after the operation of making medicated wine, increase and distill purification process, film-making again, pill.

The pharmacology of each component and function are among the present invention:

Herba Apocyni veneti has the effect of clearing away liver-fire, blood pressure lowering;

Radix Angelicae Sinensis has function of promoting blood circulation to disperse blood clots; Radix Polygoni Multiflori has the nourishing the liver and kidney effect;

Fructus Lycii has the effect of enriching yin and nourishing kidney;

Radix Salviae Miltiorrhizae has pressure-lowering and blood-activing;

The Cortex Eucommiae has hypotensive activity;

Radix Ginseng and Radix Salviae Miltiorrhizae have the heart strengthening and the mind tranquilizing, qi invigorating functions.

Fructus Crataegi is called as blood fat reducing first medicine.Contain multiple flavonoid glycoside, dimerization flavane, poly flavane etc. in fresh Fructus Crataegi and the blade, have significant blood fat reducing, heart tonifying, blood pressure lowering, antiobesity action.

The Radix Astragali Radix Astragali has the effect of strengthen shrinking to normal heart, and to because poisoning or tired depleted heart, cardiotonic is more apparent, shows as the heart contraction amplitude is increased, and discharges hypervolemia.100% Radix Astragali injection can make isolated heart shrink reinforcement, accelerate.The Radix Astragali can improve viral myocarditis patient's left ventricular function, also has certain antiarrhythmic effect, may be to prolong due to the effective refractory period.

Radix Scutellariae tincture, preserved material, decoct, alcohol or water extract, baicalin all can cause hypotensive effect to anesthetized dog, cat, intravenous rabbit, intramuscular injection or filling stomach.The oral blood pressure that can reduce normal and chronic renal hypertension dog of preserved material, tincture can make nerve hypertension dog blood pressure be back to normally.The hypotensive effect that preserved material is oral, the product person is the best with Yunnan, take second place in Hebei, northwest relatively poor.The decompression principle of Radix Scutellariae it is generally acknowledged to be direct blood vessel dilating, and also possibility vasoactive sensor causes blood pressure lowering reflectingly.

The Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.

The main component of Flos Carthami has carthamin, Flos Carthami quinone glycoside, neocarthamin and safflower yellow etc.It is suitable to get Flos Carthami

Amount is worked as tea-drinking, and company drank one month or be longer, obviously the level of hypercholesterolemia reducing, glyceryl trinitrate and non-esterified fatty acid.

The Herb Gynostemmae Pentaphylli blood pressure lowering, blood fat reducing, blood sugar lowering.Arteriosclerosis, inhibition thrombosis, the treatment cardiovascular disease.Calm the nerves and nourish one's nature, slow down aging improves mental activity, improves cerebral function.The activating human body normal cell, fat, the strengthening the spleen and stomach of losing weight, solution fatigue have calmness, hypnosis, antipsycholic action, treatment migraine anti-cancer and cancer-preventing suppresses to kill the activity that cancerous cell strengthens the blood of human body medium-sized lymphocyte, strengthen the immunologic function of human body, eliminate the toxic and side effects of hormone medicine.

Radix Puerariae is cool in nature, gas is flat, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling.Modern medicine study shows: the isoflavonoid puerarin in the Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.

The alcohol extract of Rhizoma Alismatis can disturb human body to the absorption of cholesterol, thereby cholesterol reducing and triglyceride can be selected the Rhizoma Alismatis tablets of reducing blood fat clinically.

The Flos Chrysanthemi Flos Chrysanthemi has blood pressure lowering, eliminates cancerous cell, coronary artery dilator and antibacterial effect, long-term drink can increase human body calcareous, regulate myocardial function, cholesterol reducing, drink when being fit to middle-aged and elderly people and prevention epidemic conjunctivitis.To the eyes hot-tempered, that excess eye-using causes are dry and astringent curative effect preferably arranged also.Simultaneously, chrysanthemum scented tea gives off a strong fragrance, refreshment, the effect that also has certain lax nerve, releives and have a headache.

Said medicine namely has the effect of the merit that mutual compatibility rules together, and the energy of dividing and ruling is arranged again.(1) merit of ruling together: various medicines in the prescription of the present invention, the function that blood pressure lowering is all arranged, and between every herbal medicine, have compatibility effect and can give play to maximum curative effect: the energy that divide and rule (2): various medicines are except general character, also can bring into play the therapeutical effect of its single medicine at all kinds respectively.Be that folk prescription is arranged in the compound recipe in the prescription of this invention, compound recipe is arranged in the folk prescription, can be at the patients with hypertension of various different origins.Its manufacture method science is simple, can make various dosage forms as required, as: tablet, pill, injection and medicated wine.Take the no toxic side effect in back.

The specific embodiment

EXAMPLE l

A kind of blood pressure lowering and voltage stabilizing Chinese medicine, mainly by following component and making by weight ratio:

Herba Apocyni veneti 6-30g

Radix Angelicae Sinensis 5-20g

Radix Polygoni Multiflori 10-2 0g

Fructus Lycii 10-4 0g

Cortex Eucommiae 5-2 0g

Radix Ginseng 5-10 g

Radix Salviae Miltiorrhizae 10-15 g

Fructus Crataegi 15-20 g

Radix Astragali 20-30 g

Radix Scutellariae 40-50g

Fructus Schisandrae Chinensis 40-50g

Flos Carthami 30-40g

Herb Gynostemmae Pentaphylli 40-60g

Semen Cassiae 35-45g

Radix Puerariae 40-50g

Rhizoma Alismatis 40-50g

Flos Chrysanthemi 30-40g

Adjuvant:

Chinese liquor l000-3000g

Distilled water 1200-3000g

Concrete manufacture method is:

(1) makes Chinese liquor earlier, Chinese liquor is contained in the container;

(2) said medicine is pulverized, and packed into after with the medicine mixing by said ratio and to contain in the container of wine;

(3) with container heating, steaming and decocting, boiled 30 minutes;

(4) well-done medicine filters, the filtering medicinal residues;

(5) distilled water is mixed with medicinal liquid, make blood pressure lowering medicated wine.As to make tablet, pill, and the consumption of its adjuvant of injection adopt lower limit, after the operation of making medicated wine, increase and distill purification process, film-making again, pill.

Claims (2)

1. a voltage stabilizing and Chinese hypotensor manufacture method is characterized in that: mainly by following component and make by weight ratio:

Herba Apocyni veneti 6-30g,

Radix Angelicae Sinensis 5-20g,

Radix Polygoni Multiflori 10-2 0g,

Fructus Lycii 10-4 0g,

Cortex Eucommiae 5-2 0g,

Radix Ginseng 5-10 g,

Radix Salviae Miltiorrhizae 10-15 g,

Fructus Crataegi 15-20 g,

Radix Astragali 20-30 g,

Radix Scutellariae 40-50g,

Fructus Schisandrae Chinensis 40-50g,

Flos Carthami 30-40g,

Herb Gynostemmae Pentaphylli 40-60g,

Semen Cassiae 35-45g,

Radix Puerariae 40-50g,

Rhizoma Alismatis 40-50g,

Flos Chrysanthemi 30-40g,

Adjuvant:

Chinese liquor l000-3000g,

Distilled water 1200-3000g.

2. a kind of voltage stabilizing according to claim 1 and Chinese hypotensor manufacture method is characterized in that it is that step is carried out as follows:

(1) makes Chinese liquor earlier, Chinese liquor is contained in the container;

(2) said medicine is pulverized, and packed into after with the medicine mixing by said ratio and to contain in the container of wine;

(3) with container heating, steaming and decocting, boiled 30 minutes;

(4) well-done medicine filters, the filtering medicinal residues;

(5) distilled water is mixed with medicinal liquid, makes blood pressure lowering medicated wine, as to make tablet, pill, and the consumption of its adjuvant of injection adopt lower limit, after the operation of making medicated wine, increase and distill purification process, film-making again, pill.