CN101317890A - Process for preparing capsule for urinary system lithiasis - Google Patents
Process for preparing capsule for urinary system lithiasis Download PDFInfo
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- CN101317890A CN101317890A CNA2008101406680A CN200810140668A CN101317890A CN 101317890 A CN101317890 A CN 101317890A CN A2008101406680 A CNA2008101406680 A CN A2008101406680A CN 200810140668 A CN200810140668 A CN 200810140668A CN 101317890 A CN101317890 A CN 101317890A
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Abstract
The present invention discloses a manufacturing method for a capsule which is applicable to the urinary stone. In the present invention, nine medicinal materials comprising desmodium, chicken gizzard membrane, akebia stem, twotoothed achyranthes root, lilac pink, Asiatic plantain seed, talcum, licorice root tip and amber powder are finely finished and made into dry medical powder which is mixed with magnesium stearate in proportion to be made into wet granules with ethanol as a humectant, and the wet granules are dried and filled into a capsule to obtain the capsule. The medicine of the present invention has simple and clear structure, advanced technology, easily controlled quality, high technical content, good taste and good stability, is convenient for the patient to take and does not absorb water easily; the capsule has the characteristics of high biological utilization degree and same curative effect as other preparation formulations. The preparation has reasonable design, is convenient for taking and carrying and has unique curative effect for the urinary stone.
Description
Technical field
The present invention relates to a kind of capsular medicine of urinary system calculus that is applicable to.Especially a kind of Herba Lysimachiae, Endothelium Corneum Gigeriae Galli, Caulis Akebiae etc. nine flavor Chinese crude drugs are made into the manufacture method that capsule is used for the treatment of urinary system calculus.
Background technology
Treating at present urinary system calculus disease Chinese patent medicine commonly used clinically has a lot, and they differ from one another, and goodish effect is all arranged; But the medicine of controlling urinary system calculus is still based on Western medicine, and the Western medicine effect is often too single again.Someone once designed Chinese crude drugs such as Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae was made into tablet, and adjuvant is soluble starch, Pulvis Talci, magnesium stearate, but this product stability is poor, and the moisture absorption is rotten easily, and additive is many in the tablet, and active substance content is lower, and dose is big.
Summary of the invention
The objective of the invention is to in the money, nine flavor Chinese crude drugs such as Endothelium Corneum Gigeriae Galli, Caulis Akebiae are made into a kind of capsule after extracting effective ingredient, this capsule can overcome the deficiency that existing product exists, and for urinary system calculus unique curative effect is arranged.
The present invention is achieved in that
The selected herbal raw material of the present invention is nine flavors, and it is made up of the proportioning of following parts by weight: 15 parts of Herba Lysimachiaes, 0.3 part of Endothelium Corneum Gigeriae Galli, 0.3 part of Caulis Akebiae, 0.3 part of Herba Dianthi, 0.3 part of Semen Plantaginis, 0.5 part in Talcum, Radix Glycyrrhizae are sent 0.1 part of 0.4 part, Succinum powder.
Be applicable to the capsular manufacture method of urinary system calculus: get Herba Lysimachiae, Endothelium Corneum Gigeriae Galli, Caulis Akebiae, Radix Achyranthis Bidentatae, Herba Dianthi, Semen Plantaginis, Talcum, Radix Glycyrrhizae uralensis, Succinum powder pulverize separately and become fine powder, cross 100 mesh sieves; Decoct with water secondary, the decocting that adds for the first time 8 times boiled 1.5 hours, and the decocting that adds 8 times of amounts for the second time boiled merging filtrate 1.5 hours, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder, calculate: get dried medicated powder, magnesium stearate in 1: 0.05～0.1 ratio mixing, make wet granular as wetting agent with the ethanol of simmer down to 70%～90% with composition by weight.Drying is made dried granule, and is encapsulated, promptly.
The present invention is applicable to that the urinary system calculus capsule is that it constitutes simple, clear and definite, quality and is easy to control with Herba Lysimachiae, Endothelium Corneum Gigeriae Galli, Caulis Akebiae etc. the nine flavor Chinese crude drugs medicine that to be raw material make by advanced person's preparation method, the capsule of making is the Sugarless type preparation, can increase the crowd of being suitable for, capsule is Chinese medicine advanced person's a dosage form, with high content of technology, patient's taking convenience, mouthfeel is good, be difficult for the moisture absorption, good stability; It is few that this product and tablet have been compared dose, and curative effect has the characteristics of equivalence with it.This capsule has definite curative effect to urinary system, especially urinary system calculus is had unique curative effect.Its volume is little, and is easy to carry, the standing medication that is fit to family and travels away from home.
Embodiment 1:
The method of the dried cream of extraction medical material and the manufacture method of dried medicated powder are with example 1.Calculate with composition by weight: get dried medicated powder 500g, magnesium stearate 50g mixing in 1: 0.1 ratio, edible ethanol 6ml with simmer down to 90% makes wet granular as wetting agent, dry about 70 ℃, make 1030 capsules, be up to the standards, powdery promptly gets and is applicable to the urinary system calculus capsule finished product.
The specific embodiment:
Herba Lysimachiae 15g, Endothelium Corneum Gigeriae Galli 0.3g, Caulis Akebiae 0.3g, Herba Dianthi 0.3g, Semen Plantaginis 0.3g, Talcum 0.5g, Radix Glycyrrhizae are sent 0.4g, Succinum powder 0.1g.Be ground into fine powder, cross 100 mesh sieves.Amount to the 1720g medical material, decoct with water secondary, the decocting that adds 13.76kg for the first time boiled 1.5 hours, and the decocting that adds 13.76kg for the second time boiled 1.5 hours, merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), spray drying, baking temperature is about 120 ℃, make dried cream powder,, must do medicated powder with above-mentioned fine powder mixing.Two components calculate in one: take by weighing dried medicated powder 500g, magnesium stearate 25g mixing in 1: 0.05 ratio, edible ethanol 4ml with simmer down to 70% makes wet granular as wetting agent, dry about 50 ℃, make 1000 capsules, be up to the standards, powdery promptly gets and is applicable to the urinary system calculus capsule finished product.
The function of this product cures mainly: urinary system calculus disease.
Claims (4)
1, a kind of capsular manufacture method of urinary system calculus that is applicable to is characterized in that it is to have the raw material of following parts by weight to make; 15 parts of Herba Lysimachiaes, 0.3 part of Endothelium Corneum Gigeriae Galli, 0.3 part of Caulis Akebiae, 0.3 part of Herba Dianthi, 0.3 part of Semen Plantaginis, 0.5 part in Talcum, Radix Glycyrrhizae are sent 0.1 part of 0.4 part, Succinum powder.
2, a kind of capsular manufacture method of urinary system calculus that is applicable to.It is characterized in that; Rhizoma Atractylodis, Radix Paeoniae Rubra, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Stephaniae Tetrandrae, Rhizoma Et Radix Notopterygii Herba Lysimachiae, Endothelium Corneum Gigeriae Galli, Caulis Akebiae, Radix Achyranthis Bidentatae, Herba Dianthi, Semen Plantaginis, Talcum, Radix Glycyrrhizae uralensis, Succinum powder pulverize separately become fine powder, cross 100 mesh sieves; Decoct with water the secondary merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder; Calculate with composition by weight: get dried medicated powder, make wet granular with the ethanol of simmer down to 70%～90% as wetting agent, drying is made dried granule, and is encapsulated, promptly.
3, a kind of capsular manufacture method of urinary system calculus that is applicable to according to claim 2, it is characterized in that: the temperature of spray drying chamber is 100 ℃～120 ℃.
4, a kind of capsular manufacture method of urinary system calculus that is applicable to according to claim 2 is characterized in that; The baking temperature temperature is 50 ℃～70 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406680A CN101317890A (en) | 2008-07-17 | 2008-07-17 | Process for preparing capsule for urinary system lithiasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406680A CN101317890A (en) | 2008-07-17 | 2008-07-17 | Process for preparing capsule for urinary system lithiasis |
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| Publication Number | Publication Date |
|---|---|
| CN101317890A true CN101317890A (en) | 2008-12-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101406680A Pending CN101317890A (en) | 2008-07-17 | 2008-07-17 | Process for preparing capsule for urinary system lithiasis |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110770A (en) * | 2012-12-22 | 2013-05-22 | 潘海燕 | Medicinal liquor for treating calculus |
| CN103705797A (en) * | 2013-12-17 | 2014-04-09 | 陈中元 | Drug for treating kidney stones |
| CN104138477A (en) * | 2013-05-16 | 2014-11-12 | 陈海启 | Traditional Chinese medicine composition used for treating calculi and preparation method thereof |
| CN104189267A (en) * | 2014-09-15 | 2014-12-10 | 曾成锋 | Traditional Chinese medicine composition for treating kidney stone and preparation method of traditional Chinese medicine composition |
| CN109939148A (en) * | 2019-04-24 | 2019-06-28 | 张末成 | It is a kind of to rush Paishi Mixture |
-
2008
- 2008-07-17 CN CNA2008101406680A patent/CN101317890A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110770A (en) * | 2012-12-22 | 2013-05-22 | 潘海燕 | Medicinal liquor for treating calculus |
| CN104138477A (en) * | 2013-05-16 | 2014-11-12 | 陈海启 | Traditional Chinese medicine composition used for treating calculi and preparation method thereof |
| CN104138477B (en) * | 2013-05-16 | 2017-10-13 | 陈海启 | It is a kind of to be used to treat Chinese medicine composition of calculus and preparation method thereof |
| CN103705797A (en) * | 2013-12-17 | 2014-04-09 | 陈中元 | Drug for treating kidney stones |
| CN104189267A (en) * | 2014-09-15 | 2014-12-10 | 曾成锋 | Traditional Chinese medicine composition for treating kidney stone and preparation method of traditional Chinese medicine composition |
| CN109939148A (en) * | 2019-04-24 | 2019-06-28 | 张末成 | It is a kind of to rush Paishi Mixture |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081210 |