CN101317936A - Method for preparing capsule for reliving liver and reliving upset - Google Patents
Method for preparing capsule for reliving liver and reliving upset Download PDFInfo
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- CN101317936A CN101317936A CNA2008101406036A CN200810140603A CN101317936A CN 101317936 A CN101317936 A CN 101317936A CN A2008101406036 A CNA2008101406036 A CN A2008101406036A CN 200810140603 A CN200810140603 A CN 200810140603A CN 101317936 A CN101317936 A CN 101317936A
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- reliving
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- liver
- fructus aurantii
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Abstract
The invention discloses a preparation method of a liver smoothing and depression resolving capsule. In the method, dried powder which is prepared by seven drugs of bupleurum, fructus aurantii immaturus, radix paeoniae alba, prepared glycyrrhiza, fructus aurantii, rhizome of chuanxiong and rhizoma cyperi after fine processing is uniformly mixed with magnesium stearate in proportion. With ethanol used as wetting agent, the mixture is made into wet particles to be dried and packaged in capsules to obtain the product. The preparation method of the liver smoothing and depression resolving capsule has the characteristics of simple and clear drug compositions, advanced process, easy quality control, high technique content, convenience in use for patients, good taste, uneasy moisture absorption, good stability, high bioavailability of the capsule and equivalent healing efficacy with other preparation formulations. The preparation has the advantages of reasonable design, convenience in use and carrying and is provided with specific healing efficacy for smoothing liver and resolving depression.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of the soothing liver-QI for relieving depression disease.Especially a kind of husky Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Cyperi seven flavor Chinese crude drugs are made into the manufacture method that capsule is used for the treatment of capsule for reliving liver and reliving upset.
Background technology
Treating at present soothing liver-QI for relieving depression Chinese patent medicine commonly used clinically has a lot, and they differ from one another, and goodish effect is all arranged; But the medicine of treatment soothing liver-QI for relieving depression is still based on Western medicine, and the Western medicine effect is often too single again.Someone once designed Chinese crude drugs such as Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae was made into tablet, and adjuvant is soluble starch, Pulvis Talci, magnesium stearate, but this product stability is poor, and the moisture absorption is rotten easily, and additive is many in the tablet, and active substance content is lower, and dose is big.
Summary of the invention
The objective of the invention is to Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Cyperi seven flavor Chinese crude drugs are made into a kind of capsule after extracting effective ingredient, this preparation can overcome the deficiency that existing product exists, and for soothing liver-QI for relieving depression unique curative effect is arranged.
The present invention is achieved in that
The selected herbal raw material of the present invention is ten simply, and it is made up of the proportioning of following parts by weight: 0.3 part of Radix Bupleuri, 0.2 part of Fructus Aurantii Immaturus, 0.3 part of the Radix Paeoniae Alba, 0.1 part of Radix Glycyrrhizae Preparata, 01.5 part of Fructus Aurantii, 0.2 part of Rhizoma Chuanxiong, 0.3 part of Rhizoma Cyperi.
The manufacture method of capsule for reliving liver and reliving upset: Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Cyperi pulverize separately become fine powder, cross 100 mesh sieves, decoct with water secondary, merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), spray drying, make dried cream powder, with above-mentioned fine powder mixing, must do medicated powder, calculate: get dried medicated powder, magnesium stearate in 1: 0.05～0.1 ratio mixing, make wet granular as wetting agent with the ethanol of simmer down to 70%～90% with composition by weight.Drying is made dried granule, and is encapsulated, promptly.
Capsule for reliving liver and reliving upset of the present invention is that it constitutes simple, clear and definite, quality and is easy to control with Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Fructus Aurantii, Rhizoma Chuanxiong, the Rhizoma Cyperi seven flavor Chinese crude drugs medicine that to be raw material make by advanced person's preparation method, the capsule of making is the Sugarless type preparation, can increase the crowd of being suitable for, capsule is Chinese medicine advanced person's a dosage form, with high content of technology, patient's taking convenience, mouthfeel is good, be difficult for the moisture absorption, good stability; It is few that this product and tablet have been compared dose, and curative effect has the characteristics of equivalence with it.This capsule has definite curative effect to the treatment of soothing liver-QI for relieving depression, especially soothing liver-QI for relieving depression is had unique curative effect.Its volume is little, and is easy to carry, the standing medication that is fit to family and travels away from home.
The specific embodiment:
Get Radix Bupleuri 0.3g, Fructus Aurantii Immaturus 0.2g, Radix Paeoniae Alba 0.3g, Radix Glycyrrhizae Preparata 0.1g, Fructus Aurantii 0.15g, Rhizoma Chuanxiong 0.2g, Rhizoma Cyperi 0.3g decocts with water secondary, the decocting that adds for the first time 13.76kg boiled 1.5 hours, the decocting that adds for the second time 13.76kg boiled 1.5 hours, and merging filtrate filters, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), spray drying, baking temperature are about 120 ℃, make dried cream powder, with above-mentioned fine powder mixing, must do medicated powder.Two components calculate in one: take by weighing dried medicated powder 500g, magnesium stearate 25g mixing in 1: 0.05 ratio, make wet granular as wetting agent, drying about 50 ℃ with the edible ethanol 4ml of simmer down to 70%, make capsule, be up to the standards, powdery promptly gets the capsule for reliving liver and reliving upset finished product.
Embodiment 1:
Calculate with composition by weight: get dried medicated powder 500g, magnesium stearate 50g mixing in 1: 0.1 ratio, make wet granular as wetting agent with the edible ethanol 6ml of simmer down to 90%, dry about 70 ℃, make capsule, be up to the standards, powdery promptly gets the capsule for reliving liver and reliving upset finished product.
The function of this product cures mainly: tonifying the kidney to consolidate the essence.
Claims (4)
1, a kind of manufacture method of capsule for reliving liver and reliving upset is characterized in that it is to have the raw material of following parts by weight to make; 0.3 part of Radix Bupleuri, 0.2 part of Fructus Aurantii Immaturus, 0.3 part of the Radix Paeoniae Alba, 0.1 part of Radix Glycyrrhizae Preparata, 01.5 part of Fructus Aurantii, 0.2 part of Rhizoma Chuanxiong, 0.3 part of Rhizoma Cyperi.
2, a kind of manufacture method of capsule for reliving liver and reliving upset.It is characterized in that: Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Fructus Aurantii, Rhizoma Chuanxiong, Rhizoma Cyperi pulverize separately become fine powder, cross 100 mesh sieves; Decoct with water secondary, merging filtrate filters, and it is 1.10 clear paste that filtrate is concentrated into relative density, and spray drying is made dried cream powder, and the fine powder mixing with above-mentioned obtains medicated powder; Part by weight by 1: 0.05～0.1 takes by weighing dried medicated powder, magnesium stearate mixing, makes wet granular with the ethanol of simmer down to 70%～90% as wetting agent, and drying is made dried granule, and is encapsulated, promptly.
3, the manufacture method of a kind of capsule for reliving liver and reliving upset according to claim 2 is characterized in that: the temperature of spray drying chamber is 100 ℃～120 ℃.
4, the manufacture method of a kind of capsule for reliving liver and reliving upset according to claim 2 is characterized in that; The baking temperature temperature is 50 ℃～70 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406036A CN101317936A (en) | 2008-07-15 | 2008-07-15 | Method for preparing capsule for reliving liver and reliving upset |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406036A CN101317936A (en) | 2008-07-15 | 2008-07-15 | Method for preparing capsule for reliving liver and reliving upset |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101317936A true CN101317936A (en) | 2008-12-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101406036A Pending CN101317936A (en) | 2008-07-15 | 2008-07-15 | Method for preparing capsule for reliving liver and reliving upset |
Country Status (1)
| Country | Link |
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| CN (1) | CN101317936A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698063A (en) * | 2012-06-05 | 2012-10-03 | 李承平 | Tablet for nourishing yin and soothing liver |
| CN103705611A (en) * | 2014-01-06 | 2014-04-09 | 王国强 | Traditional Chinese medicine composition and capsule application thereof |
-
2008
- 2008-07-15 CN CNA2008101406036A patent/CN101317936A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698063A (en) * | 2012-06-05 | 2012-10-03 | 李承平 | Tablet for nourishing yin and soothing liver |
| CN103705611A (en) * | 2014-01-06 | 2014-04-09 | 王国强 | Traditional Chinese medicine composition and capsule application thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081210 |