CN101317951A - Method for preparing capsule for reinforcing body fluid and nourish the blood, clearing hot, tonifying heart and pacifying the mind - Google Patents
Method for preparing capsule for reinforcing body fluid and nourish the blood, clearing hot, tonifying heart and pacifying the mind Download PDFInfo
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- CN101317951A CN101317951A CNA2008101406303A CN200810140630A CN101317951A CN 101317951 A CN101317951 A CN 101317951A CN A2008101406303 A CNA2008101406303 A CN A2008101406303A CN 200810140630 A CN200810140630 A CN 200810140630A CN 101317951 A CN101317951 A CN 101317951A
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- radix
- tranquilizing
- clearing away
- away heat
- nourishing yin
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Abstract
The present invention discloses a method for producing a capsule for replenishing yin, clearing heat, and nourishing the heart to calm mind. The method includes the following procedures: refining nine medicinal materials of radix adenophorae, nacre, dwarf lilyturf, pachyma cocos, salvia miltiorrhiza, multiflower knotweed, milkwort, shizandra berry and lotus seed; preparing the medicinal materials into dry powder and proportionally mixing the dry powder with stearic acid magnesium; taking ethanol as the moisturizing agent and preparing the mixture into particles; drying and capsulizing. The present invention has the characteristics of simple and clear composition, advanced process, easy quality control, high technological content, convenient use for patients, good taste, difficult moist absorption and good stability; the capsule is characterized by high biological utilization and equal curative effect with other dosage forms. The preparation with reasonable design, convenient use and convenient carry has the unique curative effect of replenishing yin, clearing heat, and nourishing the heart to calm mind.
Description
Technical field
The present invention relates to the capsular medicine of a kind of nourishing YIN and clearing away heat heart tonifying and tranquilizing.Especially a kind of with Radix Adenophorae (Radix Glehniae), Concha Margaritifera, Radix Ophiopogonis etc. nine the flavor Chinese crude drugs be made into the manufacture method that capsule is used for the nourishing YIN and clearing away heat heart tonifying and tranquilizing.
Background technology
Treating at present nourishing YIN and clearing away heat heart tonifying and tranquilizing disease Chinese patent medicine commonly used clinically has a lot, and they differ from one another, and goodish effect is all arranged; But the medicine of controlling the nourishing YIN and clearing away heat heart tonifying and tranquilizing is still based on Western medicine, and the Western medicine effect is often too single again.Someone once designed Chinese crude drugs such as Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae was made into tablet, and adjuvant is soluble starch, Pulvis Talci, magnesium stearate, but this product stability is poor, and the moisture absorption is rotten easily, and additive is many in the tablet, and active substance content is lower, and dose is big.
Summary of the invention
The objective of the invention is to Radix Adenophorae (Radix Glehniae), Concha Margaritifera, Radix Ophiopogonis, Poria, Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, Radix Polygalae, Fructus Schisandrae Chinensis, Plumula Nelumbinis nine flavor Chinese crude drugs are made into a kind of capsule after extracting effective ingredient, this capsule can overcome the deficiency that existing product exists, and for the nourishing YIN and clearing away heat heart tonifying and tranquilizing unique curative effect is arranged.
The present invention is achieved in that
The selected herbal raw material of the present invention is nine flavors, and it is made up of the proportioning of following parts by weight: 0.5 part of Radix Adenophorae (Radix Glehniae), 0.5 part of Concha Margaritifera, 0.3 part of Radix Ophiopogonis, 0.3 part in Poria, 0.5 part of Radix Salviae Miltiorrhizae, 0.6 part of Caulis Polygoni Multiflori, 0.2 part of Radix Polygalae, 0.2 part of Fructus Schisandrae Chinensis, 0.1 part of Plumula Nelumbinis.
The capsular manufacture method of nourishing YIN and clearing away heat heart tonifying and tranquilizing: Radix Adenophorae (Radix Glehniae), Concha Margaritifera, Radix Ophiopogonis, Poria, Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, Radix Polygalae, Fructus Schisandrae Chinensis, Plumula Nelumbinis pulverize separately become fine powder, cross 100 mesh sieves; Decoct with water secondary, the decocting that adds for the first time 8 times boiled 1.5 hours, and the decocting that adds 8 times of amounts for the second time boiled merging filtrate 1.5 hours, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder, calculate: get dried medicated powder, magnesium stearate in 1: 0.05～0.1 ratio mixing, make wet granular as wetting agent with the ethanol of simmer down to 70%～90% with composition by weight.Drying is made dried granule, and is encapsulated, promptly.
Nourishing YIN and clearing away heat heart tonifying and tranquilizing capsule of the present invention is that it constitutes simple, clear and definite, quality and is easy to control with Radix Adenophorae (Radix Glehniae), Concha Margaritifera, Radix Ophiopogonis, Poria, Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, Radix Polygalae, Fructus Schisandrae Chinensis, Plumula Nelumbinis nine flavor Chinese crude drugs medicine that to be raw material make by advanced person's preparation method, the capsule of making is the Sugarless type preparation, can increase the crowd of being suitable for, capsule is Chinese medicine advanced person's a dosage form, with high content of technology, patient's taking convenience, mouthfeel is good, be difficult for the moisture absorption, good stability; It is few that this product and tablet have been compared dose, and curative effect has the characteristics of equivalence with it.This capsule has definite curative effect to the nourishing YIN and clearing away heat heart tonifying and tranquilizing, especially the nourishing YIN and clearing away heat heart tonifying and tranquilizing is had unique curative effect.Its volume is little, and is easy to carry, the standing medication that is fit to family and travels away from home.
The specific embodiment:
Radix Adenophorae (Radix Glehniae) 0.5g, Concha Margaritifera 0.5g, Radix Ophiopogonis 0.3g, Poria 0.3g, Radix Salviae Miltiorrhizae 0.5g, Caulis Polygoni Multiflori 0.6g, Radix Polygalae 0.2g, Fructus Schisandrae Chinensis 0.2g, Plumula Nelumbinis 0.1g.Be ground into fine powder, cross 100 mesh sieves.Amount to the 1720g medical material, decoct with water secondary, the decocting that adds 13.76kg for the first time boiled 1.5 hours, and the decocting that adds 13.76kg for the second time boiled 1.5 hours, merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), spray drying, baking temperature is about 120 ℃, make dried cream powder,, must do medicated powder with above-mentioned fine powder mixing.Two components calculate in one: take by weighing dried medicated powder 500g, magnesium stearate 25g mixing in 1: 0.05 ratio, edible ethanol 4ml with simmer down to 70% makes wet granular as wetting agent, dry about 50 ℃, make capsule, be up to the standards, powdery promptly gets and is applicable to nourishing YIN and clearing away heat heart tonifying and tranquilizing capsule finished product.
Embodiment 1:
Calculate with composition by weight: get dried medicated powder 500g, magnesium stearate 50g mixing in 1: 0.1 ratio, edible ethanol 6ml with simmer down to 90% makes wet granular as wetting agent, dry about 70 ℃, make capsule, be up to the standards, powdery promptly gets and is applicable to nourishing YIN and clearing away heat heart tonifying and tranquilizing capsule finished product.
The function of this product cures mainly: the nourishing YIN and clearing away heat heart tonifying and tranquilizing.
Claims (4)
1, the capsular manufacture method of a kind of nourishing YIN and clearing away heat heart tonifying and tranquilizing is characterized in that it is to have the raw material of following parts by weight to make; 0.5 part of Radix Adenophorae (Radix Glehniae), 0.5 part of Concha Margaritifera, 0.3 part of Radix Ophiopogonis, 0.3 part in Poria, 0.5 part of Radix Salviae Miltiorrhizae, 0.6 part of Caulis Polygoni Multiflori, 0.2 part of Radix Polygalae, 0.2 part of Fructus Schisandrae Chinensis, 0.1 part of Plumula Nelumbinis.
2, the capsular manufacture method of a kind of nourishing YIN and clearing away heat heart tonifying and tranquilizing.It is characterized in that; Radix Adenophorae (Radix Glehniae), Concha Margaritifera, Radix Ophiopogonis, Poria, Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, Radix Polygalae, Fructus Schisandrae Chinensis, Plumula Nelumbinis pulverize separately become fine powder, cross 100 mesh sieves; Decoct with water the secondary merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder; Calculate with composition by weight: get dried medicated powder, make wet granular with the ethanol of simmer down to 70%～90% as wetting agent, drying is made dried granule, and is encapsulated, promptly.
3, the capsular manufacture method of a kind of nourishing YIN and clearing away heat heart tonifying and tranquilizing according to claim 2, it is characterized in that: the temperature of spray drying chamber is 100 ℃～120 ℃.
4, the capsular manufacture method of a kind of nourishing YIN and clearing away heat heart tonifying and tranquilizing according to claim 2 is characterized in that; The baking temperature temperature is 50 ℃～70 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406303A CN101317951A (en) | 2008-07-16 | 2008-07-16 | Method for preparing capsule for reinforcing body fluid and nourish the blood, clearing hot, tonifying heart and pacifying the mind |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101406303A CN101317951A (en) | 2008-07-16 | 2008-07-16 | Method for preparing capsule for reinforcing body fluid and nourish the blood, clearing hot, tonifying heart and pacifying the mind |
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| Publication Number | Publication Date |
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| CN101317951A true CN101317951A (en) | 2008-12-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2008101406303A Pending CN101317951A (en) | 2008-07-16 | 2008-07-16 | Method for preparing capsule for reinforcing body fluid and nourish the blood, clearing hot, tonifying heart and pacifying the mind |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816747A (en) * | 2010-05-13 | 2010-09-01 | 贵阳春科药业技术研发有限公司 | Medicinal preparation for preventing and treating mental diseases such as insomnia and the like and preparation method thereof |
| CN105996012A (en) * | 2016-08-12 | 2016-10-12 | 张彦优 | Sleep-improvement health product |
| CN116898929A (en) * | 2023-07-21 | 2023-10-20 | 大彭世纪科技有限公司 | Nerve-soothing brain-nourishing health-care soup |
-
2008
- 2008-07-16 CN CNA2008101406303A patent/CN101317951A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816747A (en) * | 2010-05-13 | 2010-09-01 | 贵阳春科药业技术研发有限公司 | Medicinal preparation for preventing and treating mental diseases such as insomnia and the like and preparation method thereof |
| CN101816747B (en) * | 2010-05-13 | 2014-12-17 | 贵阳春科药业技术研发有限公司 | Medicinal preparation for preventing and treating mental diseases such as insomnia and the like and preparation method thereof |
| CN105996012A (en) * | 2016-08-12 | 2016-10-12 | 张彦优 | Sleep-improvement health product |
| CN116898929A (en) * | 2023-07-21 | 2023-10-20 | 大彭世纪科技有限公司 | Nerve-soothing brain-nourishing health-care soup |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081210 |