CL2012002057A1 - Compuestos macrociclicos sustituidos, como inhibidores del virus de la hepatitis c; proceso de preparacion de dichos compuestos; composicion farmaceutica que los comprende, utiles como agente antivirales. - Google Patents
Compuestos macrociclicos sustituidos, como inhibidores del virus de la hepatitis c; proceso de preparacion de dichos compuestos; composicion farmaceutica que los comprende, utiles como agente antivirales.Info
- Publication number
- CL2012002057A1 CL2012002057A1 CL2012002057A CL2012002057A CL2012002057A1 CL 2012002057 A1 CL2012002057 A1 CL 2012002057A1 CL 2012002057 A CL2012002057 A CL 2012002057A CL 2012002057 A CL2012002057 A CL 2012002057A CL 2012002057 A1 CL2012002057 A1 CL 2012002057A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- hepatitis
- preparing
- useful
- pharmaceutical composition
- Prior art date
Links
- 241000711549 Hepacivirus C Species 0.000 title abstract 2
- 239000003443 antiviral agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000002678 macrocyclic compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos macrocíclicos sustituidos, como inhibidores del virus de la hepatitis C; proceso de preparación de dichos compuestos; composición farmacéutica que los comprende, útiles como agente antivirales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29791810P | 2010-01-25 | 2010-01-25 | |
US31430410P | 2010-03-16 | 2010-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012002057A1 true CL2012002057A1 (es) | 2013-05-10 |
Family
ID=44307283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012002057A CL2012002057A1 (es) | 2010-01-25 | 2012-07-24 | Compuestos macrociclicos sustituidos, como inhibidores del virus de la hepatitis c; proceso de preparacion de dichos compuestos; composicion farmaceutica que los comprende, utiles como agente antivirales. |
Country Status (22)
Country | Link |
---|---|
US (1) | US8785487B2 (es) |
EP (1) | EP2528436A4 (es) |
JP (1) | JP2013518060A (es) |
KR (1) | KR20120107529A (es) |
CN (1) | CN102843909A (es) |
AU (1) | AU2011207492A1 (es) |
BR (1) | BR112012018529A2 (es) |
CA (1) | CA2787309A1 (es) |
CL (1) | CL2012002057A1 (es) |
CO (1) | CO6571891A2 (es) |
CR (1) | CR20120397A (es) |
CU (1) | CU20120110A7 (es) |
EA (1) | EA201201031A1 (es) |
EC (1) | ECSP12012067A (es) |
GT (1) | GT201200230A (es) |
IL (1) | IL221033A0 (es) |
MA (1) | MA34013B1 (es) |
MX (1) | MX2012008658A (es) |
PE (1) | PE20130244A1 (es) |
SG (1) | SG188957A1 (es) |
TN (1) | TN2012000358A1 (es) |
WO (1) | WO2011091417A1 (es) |
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-
2011
- 2011-01-25 BR BR112012018529A patent/BR112012018529A2/pt not_active IP Right Cessation
- 2011-01-25 PE PE2012001072A patent/PE20130244A1/es not_active Application Discontinuation
- 2011-01-25 US US13/013,212 patent/US8785487B2/en active Active
- 2011-01-25 MX MX2012008658A patent/MX2012008658A/es not_active Application Discontinuation
- 2011-01-25 KR KR1020127022155A patent/KR20120107529A/ko not_active Application Discontinuation
- 2011-01-25 EP EP11735350.8A patent/EP2528436A4/en not_active Withdrawn
- 2011-01-25 MA MA35161A patent/MA34013B1/fr unknown
- 2011-01-25 EA EA201201031A patent/EA201201031A1/ru unknown
- 2011-01-25 CA CA2787309A patent/CA2787309A1/en not_active Abandoned
- 2011-01-25 CN CN2011800153764A patent/CN102843909A/zh active Pending
- 2011-01-25 SG SG2013016357A patent/SG188957A1/en unknown
- 2011-01-25 WO PCT/US2011/022401 patent/WO2011091417A1/en active Application Filing
- 2011-01-25 AU AU2011207492A patent/AU2011207492A1/en not_active Abandoned
- 2011-01-25 JP JP2012550208A patent/JP2013518060A/ja not_active Withdrawn
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2012
- 2012-07-16 TN TNP2012000358A patent/TN2012000358A1/en unknown
- 2012-07-19 IL IL221033A patent/IL221033A0/en unknown
- 2012-07-24 CU CU2012000110A patent/CU20120110A7/es unknown
- 2012-07-24 CL CL2012002057A patent/CL2012002057A1/es unknown
- 2012-07-25 GT GT201200230A patent/GT201200230A/es unknown
- 2012-07-25 CO CO12125014A patent/CO6571891A2/es not_active Application Discontinuation
- 2012-07-25 EC ECSP12012067 patent/ECSP12012067A/es unknown
- 2012-07-26 CR CR20120397A patent/CR20120397A/es unknown
Also Published As
Publication number | Publication date |
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SG188957A1 (en) | 2013-05-31 |
JP2013518060A (ja) | 2013-05-20 |
BR112012018529A2 (pt) | 2016-08-09 |
EP2528436A1 (en) | 2012-12-05 |
CU20120110A7 (es) | 2012-12-17 |
MA34013B1 (fr) | 2013-02-01 |
CA2787309A1 (en) | 2011-07-28 |
KR20120107529A (ko) | 2012-10-02 |
GT201200230A (es) | 2015-06-02 |
ECSP12012067A (es) | 2012-12-28 |
WO2011091417A1 (en) | 2011-07-28 |
IL221033A0 (en) | 2012-09-24 |
TN2012000358A1 (en) | 2014-01-30 |
EA201201031A1 (ru) | 2013-02-28 |
AU2011207492A1 (en) | 2012-08-16 |
CO6571891A2 (es) | 2012-11-30 |
CR20120397A (es) | 2013-05-15 |
PE20130244A1 (es) | 2013-03-10 |
US8785487B2 (en) | 2014-07-22 |
EP2528436A4 (en) | 2013-07-10 |
MX2012008658A (es) | 2012-12-05 |
US20110189129A1 (en) | 2011-08-04 |
CN102843909A (zh) | 2012-12-26 |
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