CL2012001422A1 - Compuestos derivados de sulfonil benzamidas sustituidas, inductores de apoptosis con selectividad por bcl-2; composicion farmaceutica que los comprende; y su uso para el tratamiento del cancer. - Google Patents

Compuestos derivados de sulfonil benzamidas sustituidas, inductores de apoptosis con selectividad por bcl-2; composicion farmaceutica que los comprende; y su uso para el tratamiento del cancer.

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Publication number
CL2012001422A1
CL2012001422A1 CL2012001422A CL2012001422A CL2012001422A1 CL 2012001422 A1 CL2012001422 A1 CL 2012001422A1 CL 2012001422 A CL2012001422 A CL 2012001422A CL 2012001422 A CL2012001422 A CL 2012001422A CL 2012001422 A1 CL2012001422 A1 CL 2012001422A1
Authority
CL
Chile
Prior art keywords
benzamides
bcl
selectivity
cancer
treatment
Prior art date
Application number
CL2012001422A
Other languages
English (en)
Inventor
Milan Bruncko
Hong Ding
George A Doherty
Steven W Elmore
Lisa Hasvold
Laura Hexamer
Aaron Kunzer
Robert A Mantei
William J Mcclellan
Cheol-Min Park
Andrew M Petros
Gary T Wang
Le Wang
Xilu Wang
Michael D Wendt
Todd M Hansen
Chang H Park
Xiaohong Song
Andrew J Souers
Gerard M Sullivan
Zhi-Fu Tao
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42481688&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2012001422(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of CL2012001422A1 publication Critical patent/CL2012001422A1/es

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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Abstract

Compuestos derivados de sulfonil benzamidas sustituidas, inductores de apoptosis con selectividad por Bcl-2; composición farmacéutica que los comprende; y su uso para el tratamiento del cáncer.
CL2012001422A 2009-12-04 2012-05-31 Compuestos derivados de sulfonil benzamidas sustituidas, inductores de apoptosis con selectividad por bcl-2; composicion farmaceutica que los comprende; y su uso para el tratamiento del cancer. CL2012001422A1 (es)

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