CH608784A5 - Process for the preparation of new benzylaminoalkanoic acids - Google Patents

Process for the preparation of new benzylaminoalkanoic acids

Info

Publication number
CH608784A5
CH608784A5 CH7511709A CH1170975A CH608784A5 CH 608784 A5 CH608784 A5 CH 608784A5 CH 7511709 A CH7511709 A CH 7511709A CH 1170975 A CH1170975 A CH 1170975A CH 608784 A5 CH608784 A5 CH 608784A5
Authority
CH
Switzerland
Prior art keywords
acids
benzylaminoalkanoic
preparation
new
represent hydrogen
Prior art date
Application number
CH7511709A
Inventor
Charles Malen
Pierre Roger
Jean-Claude Poignant
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Publication of CH608784A5 publication Critical patent/CH608784A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/395—Saturated compounds containing a keto group being part of a ring of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/403—Saturated compounds containing a keto group being part of a ring of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/295—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with inorganic bases, e.g. by alkali fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Saccharide Compounds (AREA)

Abstract

omega -Benzylaminoalkylcarboxylic acids of formula: <IMAGE> in which R1 represents a C3-C6 alkyl, R2 and R4 represent hydrogen or a lower alkyl, R3 represents hydrogen, a halogen, a lower alkoxy or the CF3 group, A and B represent hydrogen or a methyl or ethyl group and n represents an integer from 4 to 10, are prepared by condensation of an acid R1CO-(CAB)n-COOH with a benzylamine R3C6H4-CHR4-NHR2 under reducing conditions. These compounds, their salts and their optical isomers are novel and are distinguished by antiagressive properties; they can be used for the treatment of depressive states or of anxiety.
CH7511709A 1974-09-10 1975-09-10 Process for the preparation of new benzylaminoalkanoic acids CH608784A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3944374A GB1472627A (en) 1974-09-10 1974-09-10 Benzylaminoalkanoic acids process for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
CH608784A5 true CH608784A5 (en) 1979-01-31

Family

ID=10409574

Family Applications (1)

Application Number Title Priority Date Filing Date
CH7511709A CH608784A5 (en) 1974-09-10 1975-09-10 Process for the preparation of new benzylaminoalkanoic acids

Country Status (14)

Country Link
JP (1) JPS5645905B2 (en)
BE (1) BE833238A (en)
CA (1) CA1063619A (en)
CH (1) CH608784A5 (en)
DE (1) DE2540334C2 (en)
DK (1) DK145080C (en)
ES (1) ES440831A1 (en)
FR (1) FR2284322A1 (en)
GB (1) GB1472627A (en)
NL (1) NL166253C (en)
PH (1) PH16279A (en)
SE (1) SE420917B (en)
SU (1) SU660588A3 (en)
ZA (1) ZA755777B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1545291A (en) * 1976-03-11 1979-05-10 Science Union & Cie Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them
CA1137775A (en) * 1978-09-01 1982-12-21 Andrew J. Welebir Formulation comprising 1-triacontanol and its use as plant growth regulator
CN112920042A (en) * 2021-01-27 2021-06-08 北京岳达生物科技有限公司 Method for preparing alkane carboxylic acid by increasing alkane carbon chain

Also Published As

Publication number Publication date
DK145080B (en) 1982-08-23
ZA755777B (en) 1976-08-25
ES440831A1 (en) 1977-03-01
BE833238A (en) 1976-03-09
SU660588A3 (en) 1979-04-30
NL7510588A (en) 1976-03-12
AU8464875A (en) 1977-03-17
NL166253C (en) 1981-07-15
CA1063619A (en) 1979-10-02
DE2540334A1 (en) 1976-03-25
JPS5645905B2 (en) 1981-10-29
GB1472627A (en) 1977-05-04
PH16279A (en) 1983-08-26
DK396175A (en) 1976-03-11
SE7510024L (en) 1976-03-11
FR2284322B1 (en) 1978-07-28
DK145080C (en) 1983-01-24
JPS5159826A (en) 1976-05-25
FR2284322A1 (en) 1976-04-09
DE2540334C2 (en) 1983-03-10
NL166253B (en) 1981-02-16
SE420917B (en) 1981-11-09

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Legal Events

Date Code Title Description
PL Patent ceased