CA2512536A1 - Biomarqueurs et methodes de determination d'une sensibilite aux modulateurs du facteur de croissance epidermique - Google Patents

Biomarqueurs et methodes de determination d'une sensibilite aux modulateurs du facteur de croissance epidermique Download PDF

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Publication number
CA2512536A1
CA2512536A1 CA002512536A CA2512536A CA2512536A1 CA 2512536 A1 CA2512536 A1 CA 2512536A1 CA 002512536 A CA002512536 A CA 002512536A CA 2512536 A CA2512536 A CA 2512536A CA 2512536 A1 CA2512536 A1 CA 2512536A1
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Canada
Prior art keywords
xref
mrna
fea
est
egfr
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Abandoned
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CA002512536A
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English (en)
Inventor
Lukas C. Amler
Thomas Januario
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Bristol Myers Squibb Co
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Individual
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Publication of CA2512536A1 publication Critical patent/CA2512536A1/fr
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
CA002512536A 2003-01-08 2004-01-08 Biomarqueurs et methodes de determination d'une sensibilite aux modulateurs du facteur de croissance epidermique Abandoned CA2512536A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43873503P 2003-01-08 2003-01-08
US60/438,735 2003-01-08
PCT/US2004/000368 WO2004063709A2 (fr) 2003-01-08 2004-01-08 Biomarqueurs et methodes de determination d'une sensibilite aux modulateurs du facteur de croissance epidermique

Publications (1)

Publication Number Publication Date
CA2512536A1 true CA2512536A1 (fr) 2004-07-29

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Family Applications (1)

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CA002512536A Abandoned CA2512536A1 (fr) 2003-01-08 2004-01-08 Biomarqueurs et methodes de determination d'une sensibilite aux modulateurs du facteur de croissance epidermique

Country Status (4)

Country Link
EP (1) EP1597558A2 (fr)
JP (1) JP2007520995A (fr)
CA (1) CA2512536A1 (fr)
WO (1) WO2004063709A2 (fr)

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Also Published As

Publication number Publication date
WO2004063709A8 (fr) 2005-03-31
EP1597558A2 (fr) 2005-11-23
WO2004063709A2 (fr) 2004-07-29
JP2007520995A (ja) 2007-08-02
WO2004063709A3 (fr) 2008-05-15

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