CA1077954A - Benzobicyclononene derivatives - Google Patents

Benzobicyclononene derivatives

Info

Publication number
CA1077954A
CA1077954A CA251,293A CA251293A CA1077954A CA 1077954 A CA1077954 A CA 1077954A CA 251293 A CA251293 A CA 251293A CA 1077954 A CA1077954 A CA 1077954A
Authority
CA
Canada
Prior art keywords
bicyclo
benzo
nonene
exo
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA251,293A
Other languages
English (en)
French (fr)
Inventor
Colin L. Hewett
David S. Savage
James Redpath
Thomas Sleigh
Duncan R. Rae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzona Inc
Original Assignee
Akzona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzona Inc filed Critical Akzona Inc
Application granted granted Critical
Publication of CA1077954A publication Critical patent/CA1077954A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA251,293A 1975-04-29 1976-04-28 Benzobicyclononene derivatives Expired CA1077954A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB17846/75A GB1549172A (en) 1975-04-29 1975-04-29 Benzobicyclononene derivatives

Publications (1)

Publication Number Publication Date
CA1077954A true CA1077954A (en) 1980-05-20

Family

ID=10102255

Family Applications (1)

Application Number Title Priority Date Filing Date
CA251,293A Expired CA1077954A (en) 1975-04-29 1976-04-28 Benzobicyclononene derivatives

Country Status (16)

Country Link
JP (1) JPS51131868A (nl)
AU (1) AU501107B2 (nl)
BE (1) BE841244A (nl)
CA (1) CA1077954A (nl)
CH (2) CH628612A5 (nl)
DE (1) DE2618721C2 (nl)
DK (1) DK187076A (nl)
FI (1) FI64573C (nl)
FR (1) FR2309218A1 (nl)
GB (1) GB1549172A (nl)
HU (1) HU176463B (nl)
IE (1) IE44118B1 (nl)
LU (1) LU74856A1 (nl)
NL (1) NL7506408A (nl)
SE (1) SE433744B (nl)
ZA (1) ZA762359B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570613A (en) * 1976-10-27 1980-07-02 Akzo Nv Biologically active tricyclic compounds and pharmaceutical compositions containing same
GB8606061D0 (en) * 1986-03-12 1986-04-16 Akzo Nv Tricyclic amino compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA717697B (en) * 1970-12-03 1973-06-27 American Home Prod Benzobicycloalkane amines

Also Published As

Publication number Publication date
FR2309218B1 (nl) 1978-08-25
DE2618721A1 (de) 1976-11-11
FI64573B (fi) 1983-08-31
DE2618721C2 (de) 1986-06-05
DK187076A (da) 1976-10-30
ZA762359B (en) 1977-04-27
CH628612A5 (en) 1982-03-15
BE841244A (fr) 1976-10-28
IE44118L (en) 1976-10-29
AU501107B2 (en) 1979-06-14
NL7506408A (nl) 1976-11-02
AU1328976A (en) 1977-10-27
IE44118B1 (en) 1981-08-26
GB1549172A (en) 1979-08-01
HU176463B (en) 1981-03-28
FR2309218A1 (fr) 1976-11-26
LU74856A1 (nl) 1977-01-12
JPS6154776B2 (nl) 1986-11-25
SE433744B (sv) 1984-06-12
SE7604861L (sv) 1976-10-30
FI64573C (fi) 1983-12-12
JPS51131868A (en) 1976-11-16
FI761189A (nl) 1976-10-30
CH632985A5 (en) 1982-11-15

Similar Documents

Publication Publication Date Title
HU194167B (en) Process for production og byciclic derivatives of carbonic acid
JPS6238348B2 (nl)
US3420851A (en) Novel dibenzoxepines
US3703529A (en) Nitrogen-containing tricyclic compounds
EP0151539A2 (en) Benzobicyclic lactam acids, their derivatives, an intermediate in the preparation thereof and processes for the production thereof
Boger et al. Benzylic hydroperoxide rearrangement: observations on a viable and convenient alternative to the Baeyer-Villiger rearrangement
US2957872A (en) Phthalimidines and process for manufacturing same
US4299984A (en) Benzo-bicyclononene-derivatives
CA1077954A (en) Benzobicyclononene derivatives
Brossi et al. Selective O-demethylation of papaverine
US3631039A (en) 2-amino ethyl-2-hydroxy - 6-vinyl tetrahydropyrans tautomers and optical enantiomers thereof
US4156694A (en) Benzobicyclononene derivatives
US4316029A (en) Synthesis of vincaminic acid derivatives
US4107206A (en) Benzo-bicyclononene- derivatives
US4153791A (en) 3-Carboxy-4 hydroxyphenylthioacetmorpholide
US3131190A (en) 9-aminoalkyl and 9-aminoalkylidene derivatives of acridan
GB1568407A (en) Bicyclicpentol derivatives
US3696121A (en) 4-(2-hydroxy-3-amino propoxy)-indole derivatives
US3390179A (en) Novel 10, 11-dihydro-10, 11-dihydroxy-(3-substituted aminopropylidene)-5h-dibenzo [a, d] cycloheptenes
CA1081704A (en) Biologically active tricyclic compounds and pharmaceutical compositions containing same
EP0564648A1 (en) Novel aconitine compound and analgesic/antiinflammatory agent
US5716986A (en) Oxaindene derivatives and process for the preparation thereof
US2986562A (en) Reserpic and deserpidic acid lactone dienes
EP0004960A1 (en) 9.9-Dimethyl-6.7-benzomorphan derivatives, processes for their preparation and pharmaceutical compositions comprising them
Müller et al. The Synthesis of n, n‐Dimethyl‐2‐(1‐phenyl‐2, 5‐cyclohexadien‐1‐yl)‐ethylamine and of Mesembrine‐Like Metabolites of this Potential Analgesic

Legal Events

Date Code Title Description
MKEX Expiry