BRPI0921705B8 - composição farmacêutica antimicrobiana e seu uso - Google Patents

composição farmacêutica antimicrobiana e seu uso

Info

Publication number
BRPI0921705B8
BRPI0921705B8 BRPI0921705A BRPI0921705A BRPI0921705B8 BR PI0921705 B8 BRPI0921705 B8 BR PI0921705B8 BR PI0921705 A BRPI0921705 A BR PI0921705A BR PI0921705 A BRPI0921705 A BR PI0921705A BR PI0921705 B8 BRPI0921705 B8 BR PI0921705B8
Authority
BR
Brazil
Prior art keywords
compositions
pharmaceutical composition
antimicrobial pharmaceutical
antimicrobial
tolerability
Prior art date
Application number
BRPI0921705A
Other languages
English (en)
Inventor
Beurer Lord Danielle
Li Danping
S Dresback David
S Burak Eric
Original Assignee
Melinta Subsidiary Corp
Melinta Therapeutics Inc
Rib X Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42170697&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0921705(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Melinta Subsidiary Corp, Melinta Therapeutics Inc, Rib X Pharmaceuticals Inc filed Critical Melinta Subsidiary Corp
Priority to BR122020021551-8A priority Critical patent/BR122020021551B1/pt
Publication of BRPI0921705A2 publication Critical patent/BRPI0921705A2/pt
Publication of BRPI0921705B1 publication Critical patent/BRPI0921705B1/pt
Publication of BRPI0921705B8 publication Critical patent/BRPI0921705B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Abstract

composições antimicrobianas. a presente invenção refere-se a composições antimicrobianas e, mais especificamente, a composições de derivados de ácido carboxílico quinolona. estas composições têm solubilidade, estabilidade e capacidade de tolerância aperfeiçoadas. estas composições são úteis para administração intravenosa para tratar, prevenir ou reduzir o risco de infecção.
BRPI0921705A 2008-11-15 2009-11-12 composição farmacêutica antimicrobiana e seu uso BRPI0921705B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122020021551-8A BR122020021551B1 (pt) 2008-11-15 2009-11-12 Composição farmacêutica antimicrobiana e seu uso

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19925308P 2008-11-15 2008-11-15
US61/199,253 2008-11-15
PCT/US2009/064220 WO2010056872A2 (en) 2008-11-15 2009-11-12 Antimicrobial compositions

Publications (3)

Publication Number Publication Date
BRPI0921705A2 BRPI0921705A2 (pt) 2015-08-25
BRPI0921705B1 BRPI0921705B1 (pt) 2021-01-19
BRPI0921705B8 true BRPI0921705B8 (pt) 2021-05-25

Family

ID=42170697

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0921705A BRPI0921705B8 (pt) 2008-11-15 2009-11-12 composição farmacêutica antimicrobiana e seu uso
BR122020021551-8A BR122020021551B1 (pt) 2008-11-15 2009-11-12 Composição farmacêutica antimicrobiana e seu uso

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122020021551-8A BR122020021551B1 (pt) 2008-11-15 2009-11-12 Composição farmacêutica antimicrobiana e seu uso

Country Status (24)

Country Link
US (4) US20120065186A1 (pt)
EP (1) EP2373166A4 (pt)
JP (3) JP6063123B2 (pt)
KR (1) KR101767689B1 (pt)
CN (3) CN103705942B (pt)
AU (1) AU2009314072C1 (pt)
BR (2) BRPI0921705B8 (pt)
CA (1) CA2743419C (pt)
CO (1) CO6382082A2 (pt)
CR (1) CR20110320A (pt)
EA (1) EA025637B1 (pt)
EC (1) ECSP11011119A (pt)
HK (1) HK1213821A1 (pt)
IL (1) IL212781A (pt)
MA (1) MA32931B1 (pt)
MX (1) MX2011005117A (pt)
MY (3) MY161597A (pt)
NI (1) NI201100097A (pt)
NZ (1) NZ593345A (pt)
PE (2) PE20160116A1 (pt)
SV (1) SV2011003907A (pt)
UA (1) UA102709C2 (pt)
WO (1) WO2010056872A2 (pt)
ZA (1) ZA201104108B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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MY161597A (en) * 2008-11-15 2017-04-28 Rib-X Pharmaceuticals Inc Antimicrobial compositions
SG10201506273PA (en) * 2011-11-29 2015-09-29 Jurox Pty Ltd Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
JP6395200B2 (ja) * 2012-10-22 2018-09-26 ジェクス株式会社 ケイ素含有化合物水溶液及び該水溶液を含む抗菌・抗ウィルス剤
JP2016511273A (ja) * 2013-03-08 2016-04-14 メリンタ セラピューティクス、インク Ｄ−グルシトール，１−デオキシ−１−（メチルアミノ）−，１−（６−アミノ−３，５−ジフルオロピリジン−２−イル）−８−クロロ−６−フルオロ−１，４−ジヒドロ−７−（３−ヒドロキシアゼチジン−１−イル）−４−オキソ−３−キノリンカルボン酸塩の結晶型
BR112015023044A8 (pt) * 2013-03-15 2021-09-28 Melinta Subsidiary Corp Métodos para tratar infecções em pacientes acima do peso e obesos com o uso de antibióticos
HUE053654T2 (hu) 2014-03-26 2021-07-28 Astex Therapeutics Ltd FGFR- és CMET-inhibitorok kombinációi a rák kezelésére
TWI705814B (zh) * 2014-06-20 2020-10-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
TW201605447A (zh) * 2014-06-20 2016-02-16 美林塔治療學有限公司 處理感染的方法
CN105693695A (zh) * 2014-11-24 2016-06-22 重庆医药工业研究院有限责任公司 一种德拉沙星葡甲胺盐的晶型及其制备方法
JOP20200201A1 (ar) 2015-02-10 2017-06-16 Astex Therapeutics Ltd تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين
KR102429646B1 (ko) 2016-03-14 2022-08-04 산텐 세이야꾸 가부시키가이샤 메글루민 또는 그의 염을 포함하는 방부제
CN107789323B (zh) * 2016-08-31 2021-05-07 鲁南制药集团股份有限公司 一种注射用德拉沙星葡甲胺冻干制剂及其制备方法
CN107789324B (zh) * 2016-08-31 2021-05-25 鲁南制药集团股份有限公司 一种注射用德拉沙星葡甲胺及其制备方法
SG11201907433TA (en) * 2017-02-15 2019-09-27 Taiho Pharmaceutical Co Ltd Pharmaceutical composition

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MY161597A (en) * 2008-11-15 2017-04-28 Rib-X Pharmaceuticals Inc Antimicrobial compositions

Also Published As

Publication number Publication date
CN102215690B (zh) 2015-07-01
CA2743419C (en) 2017-02-14
CR20110320A (es) 2011-10-18
JP2012508757A (ja) 2012-04-12
JP2017031164A (ja) 2017-02-09
AU2009314072B2 (en) 2016-05-19
ZA201104108B (en) 2012-09-26
US20200022971A1 (en) 2020-01-23
WO2010056872A3 (en) 2010-07-29
CN104958296A (zh) 2015-10-07
CN104958296B (zh) 2017-12-01
WO2010056872A2 (en) 2010-05-20
HK1213821A1 (zh) 2016-07-15
JP2015091856A (ja) 2015-05-14
ECSP11011119A (es) 2011-11-30
US20220265636A1 (en) 2022-08-25
EP2373166A2 (en) 2011-10-12
PE20160116A1 (es) 2016-03-09
CA2743419A1 (en) 2010-05-20
JP6407221B2 (ja) 2018-10-17
UA102709C2 (uk) 2013-08-12
KR20120008020A (ko) 2012-01-25
CN103705942A (zh) 2014-04-09
CN102215690A (zh) 2011-10-12
BR122020021551B1 (pt) 2021-09-21
JP6063123B2 (ja) 2017-01-18
SV2011003907A (es) 2011-12-06
EP2373166A4 (en) 2014-11-05
MY161597A (en) 2017-04-28
BRPI0921705B1 (pt) 2021-01-19
MX2011005117A (es) 2011-10-21
PE20120029A1 (es) 2012-02-13
EA025637B1 (ru) 2017-01-30
IL212781A (en) 2016-12-29
MA32931B1 (fr) 2012-01-02
NZ593345A (en) 2013-04-26
KR101767689B1 (ko) 2017-08-11
CO6382082A2 (es) 2012-02-15
NI201100097A (es) 2011-09-08
US20160235736A1 (en) 2016-08-18
CN103705942B (zh) 2016-08-24
AU2009314072A1 (en) 2011-06-30
BRPI0921705A2 (pt) 2015-08-25
AU2009314072C1 (en) 2016-11-10
MY188453A (en) 2021-12-09
MY194407A (en) 2022-11-30
IL212781A0 (en) 2011-07-31
EA201170689A1 (ru) 2013-10-30
US20120065186A1 (en) 2012-03-15

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