BRPI0910282A2 - Composto oxadiazo-antraceno para o tratamento de diabetes - Google Patents

Composto oxadiazo-antraceno para o tratamento de diabetes

Info

Publication number: BRPI0910282A2
Authority: BR; Brazil
Prior art keywords: oxadiazo; anthracene compound; diabetes treatment; diabetes; treatment
Prior art date: 2008-03-07

Application number

BRPI0910282-5A

Other languages

English (en)

Inventor

Adnan M M Mjalli

Dharma Rao Polisetti

Thomas Scott Yokum

Kalpathy Santhosh

Mustafa Guzel

Christopher Behme

Stephen Thomas Davis

Original Assignee

Transtech Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-07

Filing date

2009-03-06

Publication date

2015-09-01

2009-03-06 Application filed by Transtech Pharma Inc filed Critical Transtech Pharma Inc

2015-09-01 Publication of BRPI0910282A2 publication Critical patent/BRPI0910282A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0910282-5A 2008-03-07 2009-03-06 Composto oxadiazo-antraceno para o tratamento de diabetes BRPI0910282A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US3459908P	2008-03-07	2008-03-07
PCT/US2009/036333 WO2009111700A2 (en)	2008-03-07	2009-03-06	Oxadiazoanthracene compounds for the treatment of diabetes

Publications (1)

Publication Number	Publication Date
BRPI0910282A2 true BRPI0910282A2 (pt)	2015-09-01

Family

ID=41056666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0910282-5A BRPI0910282A2 (pt)	2008-03-07	2009-03-06	Composto oxadiazo-antraceno para o tratamento de diabetes

Country Status (18)

Country	Link
US (7)	US7727983B2 (pt)
EP (1)	EP2262364B1 (pt)
JP (1)	JP5382952B2 (pt)
KR (1)	KR101616737B1 (pt)
CN (1)	CN101959405B (pt)
AU (1)	AU2009221722B2 (pt)
BR (1)	BRPI0910282A2 (pt)
CA (1)	CA2716664C (pt)
DK (1)	DK2262364T3 (pt)
EA (1)	EA018225B1 (pt)
ES (1)	ES2567451T3 (pt)
HK (1)	HK1148435A1 (pt)
IL (1)	IL207570A (pt)
MA (1)	MA32175B1 (pt)
MX (1)	MX2010009752A (pt)
NZ (1)	NZ587343A (pt)
WO (1)	WO2009111700A2 (pt)
ZA (1)	ZA201006367B (pt)

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NZ587343A (en)	2008-03-07	2012-05-25	Transtech Pharma Inc	Oxadiazoanthracene compounds for the treatment of diabetes
BRPI1013579A2 (pt)	2009-03-30	2020-11-03	Transtech Pharma, Inc.	derivados de azoantraceno substituídos, composições farmacêuticas e métodos de uso dos mesmos
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
DE102010015123A1 (de)	2010-04-16	2011-10-20	Sanofi-Aventis Deutschland Gmbh	Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
CN103261165B (zh)	2010-12-23	2015-08-26	辉瑞公司	胰高血糖素受体调节剂
WO2012096824A1 (en)	2011-01-12	2012-07-19	Transtech Pharma, Inc.	Phenylglyoxylic acid derivatives and their preparation and use
JP5562495B2 (ja)	2011-02-08	2014-07-30	ファイザー・インク	グルカゴン受容体モジュレーター
ES2550345T3 (es)	2011-07-22	2015-11-06	Pfizer Inc.	Moduladores del receptor de quinolinilglucagón
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CN104202977A (zh) *	2012-03-22	2014-12-10	转化技术制药有限责任公司	小分子glp1r激动剂的三(羟甲基)氨基甲烷盐及其药物组合物和用途
WO2014064215A1 (en)	2012-10-24	2014-05-01	INSERM (Institut National de la Santé et de la Recherche Médicale)	TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
JP6445459B2 (ja) *	2013-01-17	2018-12-26	ブイティーブイ・セラピューティクス・エルエルシー	Ｇｌｐ１ｒアゴニストとメトホルミンの組合わせおよび２型糖尿病その他の障害の処置のためのその使用
KR102564946B1 (ko) *	2014-07-25	2023-08-08	리셉토스 엘엘씨	신규 glp-1 수용체 조절제
US10426818B2 (en)	2015-03-24	2019-10-01	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Method and pharmaceutical composition for use in the treatment of diabetes
JOP20190060A1 (ar)	2016-09-26	2019-03-26	Chugai Pharmaceutical Co Ltd	مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
WO2019103060A1 (ja) *	2017-11-22	2019-05-31	第一三共株式会社	縮合三環化合物
AU2019266114A1 (en)	2018-05-08	2020-08-27	Vtv Therapeutics Llc	Therapeutic uses of GLP1R agonists
TW202144340A (zh)	2020-04-03	2021-12-01	大陸商江蘇恆瑞醫藥股份有限公司	稠合咪唑類衍生物、其製備方法及其在醫藥上的應用
US20230348484A1 (en) *	2020-05-28	2023-11-02	Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.	Method for preparing glp-1 receptor agonist free base
EP4159719A1 (en) *	2020-05-28	2023-04-05	Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd.	Preparation method for (s)-2-amino-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)methyl propionate diacid salt
US20230322756A1 (en)	2020-09-01	2023-10-12	Jiangsu Hengrui Medicine Co., Ltd.	Fused imidazole derivative, preparation method therefor, and medical use thereof
WO2022078152A1 (zh)	2020-10-12	2022-04-21	杭州中美华东制药有限公司	苯并咪唑酮类glp-1受体激动剂及其用途
MX2023006186A (es)	2020-11-27	2023-08-07	Shenzhen Salubris Pharm Co Ltd	Derivado de benzimidazol y método de preparación del mismo y uso médico del mismo.
EP4317142A1 (en)	2021-03-22	2024-02-07	Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd.	Thiophene glp-1 receptor agonist and use thereof
EP4317145A1 (en)	2021-03-24	2024-02-07	Shionogi & Co., Ltd	Pharmaceutical composition containing glp-1 receptor agonist having fused ring
WO2022262615A1 (zh) *	2021-06-17	2022-12-22	杭州中美华东制药有限公司	蒽类化合物、其制备方法和医药用途
KR20240024910A (ko)	2021-06-24	2024-02-26	항저우 종메이화동 파마슈티칼 컴퍼니 리미티드	Glp-1 수용체 작용제 및 이의 조성물과 용도
CN115521320B (zh) *	2021-06-25	2023-09-05	沈阳兴齐眼药股份有限公司	一种制备普拉洛芬的方法

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EP0233728A1 (en) *	1986-02-11	1987-08-26	Takeda Chemical Industries, Ltd.	1,4-Benzoxazine derivatives their production and use
JPS6345270A (ja) *	1986-02-11	1988-02-26	Takeda Chem Ind Ltd	１，４−ベンゾオキサジン誘導体，その製造法およびそれを含有する医薬用組成物
JP2002515025A (ja) *	1995-10-06	2002-05-21	リガンド・ファーマシューティカルズ・インコーポレイテッド	ダイマー選択的ｒｘｒモジュレーターおよびその使用方法
JP2002534512A (ja) *	1999-01-15	2002-10-15	ノボノルディスクアクティーゼルスカブ	非ペプチドｇｌｐ−１アゴニスト
RU2256661C2 (ru) *	1999-12-03	2005-07-20	Киото Фармасьютикал Индастриз, Лтд.	Производные тетрагидроизохинолина и их соли и фармацевтическая композиция на их основе
EP1125925A1 (en)	2000-02-15	2001-08-22	Applied Research Systems ARS Holding N.V.	Amine derivatives for the treatment of apoptosis
US20050222036A1 (en)	2000-08-24	2005-10-06	Thomas Jefferson University	Peptide compositions with effects on blood glucose
CN100432056C (zh) *	2003-03-26	2008-11-12	埃科特莱茵药品有限公司	四氢异喹啉基乙酰胺衍生物作为阿立新受体拮抗剂的应用
NZ587343A (en) *	2008-03-07	2012-05-25	Transtech Pharma Inc	Oxadiazoanthracene compounds for the treatment of diabetes
US8501982B2 (en)	2010-06-09	2013-08-06	Receptos, Inc.	GLP-1 receptor stabilizers and modulators

2009
- 2009-03-06 NZ NZ587343A patent/NZ587343A/en not_active IP Right Cessation
- 2009-03-06 MX MX2010009752A patent/MX2010009752A/es active IP Right Grant
- 2009-03-06 DK DK09718287.7T patent/DK2262364T3/en active
- 2009-03-06 WO PCT/US2009/036333 patent/WO2009111700A2/en active Application Filing
- 2009-03-06 ES ES09718287T patent/ES2567451T3/es active Active
- 2009-03-06 KR KR1020107020688A patent/KR101616737B1/ko active IP Right Grant
- 2009-03-06 BR BRPI0910282-5A patent/BRPI0910282A2/pt not_active Application Discontinuation
- 2009-03-06 CN CN200980108115.XA patent/CN101959405B/zh active Active
- 2009-03-06 EA EA201071045A patent/EA018225B1/ru not_active IP Right Cessation
- 2009-03-06 EP EP09718287.7A patent/EP2262364B1/en active Active
- 2009-03-06 AU AU2009221722A patent/AU2009221722B2/en active Active
- 2009-03-06 JP JP2010549910A patent/JP5382952B2/ja active Active
- 2009-03-06 US US12/399,504 patent/US7727983B2/en active Active
- 2009-03-06 CA CA2716664A patent/CA2716664C/en active Active
2010
- 2010-04-13 US US12/759,010 patent/US7790714B2/en active Active
- 2010-08-03 US US12/849,225 patent/US7906507B2/en active Active
- 2010-08-12 IL IL207570A patent/IL207570A/en active IP Right Grant
- 2010-08-31 US US12/872,580 patent/US8524708B2/en not_active Expired - Fee Related
- 2010-09-10 ZA ZA2010/06367A patent/ZA201006367B/en unknown
- 2010-09-30 MA MA33212A patent/MA32175B1/fr unknown
2011
- 2011-03-14 HK HK11102525.7A patent/HK1148435A1/xx unknown
2013
- 2013-08-01 US US13/956,578 patent/US8703766B2/en not_active Expired - Fee Related
2014
- 2014-03-05 US US14/197,771 patent/US8933222B2/en active Active
- 2014-12-01 US US14/556,837 patent/US9120813B2/en active Active

Also Published As

Publication number	Publication date
US20130317015A1 (en)	2013-11-28
EA201071045A1 (ru)	2011-02-28
US8524708B2 (en)	2013-09-03
CN101959405B (zh)	2014-07-02
AU2009221722B2 (en)	2014-12-18
US20140187769A1 (en)	2014-07-03
KR20100131455A (ko)	2010-12-15
AU2009221722A1 (en)	2009-09-11
EP2262364A2 (en)	2010-12-22
IL207570A0 (en)	2010-12-30
CN101959405A (zh)	2011-01-26
US8933222B2 (en)	2015-01-13
WO2009111700A2 (en)	2009-09-11
US7906507B2 (en)	2011-03-15
NZ587343A (en)	2012-05-25
US20100197677A1 (en)	2010-08-05
JP2011513431A (ja)	2011-04-28
US20150087640A1 (en)	2015-03-26
HK1148435A1 (en)	2011-09-09
US20090306063A1 (en)	2009-12-10
KR101616737B1 (ko)	2016-05-02
US7790714B2 (en)	2010-09-07
EA018225B1 (ru)	2013-06-28
ZA201006367B (en)	2011-05-25
WO2009111700A3 (en)	2010-03-04
US9120813B2 (en)	2015-09-01
JP5382952B2 (ja)	2014-01-08
US7727983B2 (en)	2010-06-01
MA32175B1 (fr)	2011-03-01
MX2010009752A (es)	2010-09-30
US8703766B2 (en)	2014-04-22
EP2262364A4 (en)	2012-04-04
IL207570A (en)	2014-03-31
CA2716664C (en)	2016-10-11
US20100324033A1 (en)	2010-12-23
CA2716664A1 (en)	2009-09-11
EP2262364B1 (en)	2016-03-02
DK2262364T3 (en)	2016-03-21
ES2567451T3 (es)	2016-04-22
US20110039837A1 (en)	2011-02-17

Legal Events

Date	Code	Title	Description
2016-08-23	B25D	Requested change of name of applicant approved	Owner name: VTV THERAPEUTICS LLC (US)
2016-09-06	B25D	Requested change of name of applicant approved	Owner name: VTVX HOLDINGS I LLC (US)
2016-09-27	B25A	Requested transfer of rights approved	Owner name: VTV THERAPEUTICS LLC (US)
2018-01-23	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-05-21	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-12-31	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 11A ANUIDADE.
2020-06-23	B11B	Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements

Publication	Publication Date	Title
BRPI0910282A2 (pt)	2015-09-01	Composto oxadiazo-antraceno para o tratamento de diabetes
LTPA2019009I1 (lt)	2019-04-10	C7-fluoru pakeisti tetraciklino junginiai
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DK2242759T3 (da)	2012-12-17	Forbindelser
BRPI0908874A2 (pt)	2015-11-24	mecanismo de posicionamento de um leito
BRPI0716134A2 (pt)	2013-09-17	tratamento de combinaÇço para diabetes mellitus
BR112012000502A2 (pt)	2017-05-16	terapia de combinação para o tratamento de diabetes
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DK2297162T3 (da)	2012-11-26	Forbindelser
BRPI0922884A2 (pt)	2018-11-06	compostos para tratamento de câncer
BRPI0916432A2 (pt)	2016-02-16	compostos
DK2271618T3 (da)	2014-06-16	Farmaceutiske forbindelser
BRPI0821827A2 (pt)	2015-06-16	Derivados de beta-aminoácidos para tratamento de diabetes
BRPI0923592A2 (pt)	2016-01-26	composto
BRPI0911393A2 (pt)	2015-12-29	composto de 5-hidroxipirimidina-4-carboxamida
BRPI0920728A2 (pt)	2015-08-18	Composição estabilizada para tratamento de psoríase
BRPI0918508A2 (pt)	2015-12-08	orto-aminoanilidas para o tratamento de câncer
DK2206698T3 (da)	2012-08-27	Ethynylindolforbindelser
BRPI0922152A2 (pt)	2015-08-18	Compostos
BRPI0913872A2 (pt)	2015-10-27	multi-bandagem