BRPI0907844B8 - compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos - Google Patents

compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos

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Publication number
BRPI0907844B8
BRPI0907844B8 BRPI0907844A BRPI0907844A BRPI0907844B8 BR PI0907844 B8 BRPI0907844 B8 BR PI0907844B8 BR PI0907844 A BRPI0907844 A BR PI0907844A BR PI0907844 A BRPI0907844 A BR PI0907844A BR PI0907844 B8 BRPI0907844 B8 BR PI0907844B8
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BR
Brazil
Prior art keywords
compounds
androgen receptor
modulating
formulas
pharmaceutical composition
Prior art date
Application number
BRPI0907844A
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English (en)
Inventor
P Miller Chris
Original Assignee
Radius Health Inc
Radius Pharmaceuticals Inc
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Publication date
Application filed by Radius Health Inc, Radius Pharmaceuticals Inc filed Critical Radius Health Inc
Publication of BRPI0907844A2 publication Critical patent/BRPI0907844A2/pt
Publication of BRPI0907844B1 publication Critical patent/BRPI0907844B1/pt
Publication of BRPI0907844B8 publication Critical patent/BRPI0907844B8/pt

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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

moduladores seletivos do receptor de andrógeno. a presente invenção refere-se a compostos de formulas (i), la, ib, ic, id, le e ou seus sais, composições farmacêuticas que compreendem um composto de fórmulas i, la, ib, ic, id, le e um excipiente farmaceuticamente aceitável,métodos para modular o receptor de andrógeno, métodos para tratar doenças beneficamente tratadas por um modulador de andrógeno (por exemplo, sarcopenia, câncer da próstata, anticoncepção, distúrbios ou doenças relacionadas com a diabetes tipo 2, anemia, depressão e doença renal) e processos para preparar os compostos de fórmulas (i), la, ib, ic, id,le e intermediários úteis na preparação dos mesmos.
BRPI0907844A 2008-02-22 2009-02-19 compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos BRPI0907844B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US6669708P 2008-02-22 2008-02-22
US61/066,697 2008-02-22
US13235308P 2008-06-18 2008-06-18
US61/132,353 2008-06-18
US20572709P 2009-01-21 2009-01-21
US61/205,727 2009-01-21
PCT/US2009/001035 WO2009105214A2 (en) 2008-02-22 2009-02-19 Selective androgen receptor modulators

Publications (3)

Publication Number Publication Date
BRPI0907844A2 BRPI0907844A2 (pt) 2018-01-30
BRPI0907844B1 BRPI0907844B1 (pt) 2020-08-18
BRPI0907844B8 true BRPI0907844B8 (pt) 2021-05-25

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BRPI0907844A BRPI0907844B8 (pt) 2008-02-22 2009-02-19 compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos

Country Status (9)

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US (2) US8067448B2 (pt)
EP (1) EP2260028B1 (pt)
JP (1) JP5308458B2 (pt)
AU (1) AU2009215843B2 (pt)
BR (1) BRPI0907844B8 (pt)
CA (1) CA2716320C (pt)
ES (1) ES2488990T3 (pt)
MX (1) MX2010009162A (pt)
WO (1) WO2009105214A2 (pt)

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AU2009215843A1 (en) 2009-08-27
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MX2010009162A (es) 2010-12-21
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WO2009105214A2 (en) 2009-08-27
US20110224267A1 (en) 2011-09-15
US8067448B2 (en) 2011-11-29
EP2260028A2 (en) 2010-12-15
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AU2009215843B2 (en) 2011-09-08
BRPI0907844B1 (pt) 2020-08-18
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US8455525B2 (en) 2013-06-04
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