BRPI0814988A2 - Hidridização in-situ para detectar marcadores de rna e dna. - Google Patents

Hidridização in-situ para detectar marcadores de rna e dna.

Info

Publication number
BRPI0814988A2
BRPI0814988A2 BRPI0814988-7A2A BRPI0814988A BRPI0814988A2 BR PI0814988 A2 BRPI0814988 A2 BR PI0814988A2 BR PI0814988 A BRPI0814988 A BR PI0814988A BR PI0814988 A2 BRPI0814988 A2 BR PI0814988A2
Authority
BR
Brazil
Prior art keywords
hidridization
situ
dna markers
detect rna
rna
Prior art date
Application number
BRPI0814988-7A2A
Other languages
English (en)
Inventor
Wen-Hua Fan
Roger Tim
Ram Bhatt
Original Assignee
Biocept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocept Inc filed Critical Biocept Inc
Publication of BRPI0814988A2 publication Critical patent/BRPI0814988A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/107Temperature of melting, i.e. Tm
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0814988-7A2A 2007-08-03 2008-08-04 Hidridização in-situ para detectar marcadores de rna e dna. BRPI0814988A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95381207P 2007-08-03 2007-08-03
PCT/US2008/072143 WO2009020932A2 (en) 2007-08-03 2008-08-04 In-situ hybridization to detect rna and dna markers

Publications (1)

Publication Number Publication Date
BRPI0814988A2 true BRPI0814988A2 (pt) 2015-02-03

Family

ID=40341985

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814988-7A2A BRPI0814988A2 (pt) 2007-08-03 2008-08-04 Hidridização in-situ para detectar marcadores de rna e dna.

Country Status (10)

Country Link
US (1) US20110287415A1 (pt)
EP (1) EP2173913A4 (pt)
JP (1) JP2010535475A (pt)
KR (1) KR20100044878A (pt)
CN (1) CN101809171A (pt)
AU (1) AU2008284024A1 (pt)
BR (1) BRPI0814988A2 (pt)
CA (1) CA2695369A1 (pt)
MX (1) MX2010001380A (pt)
WO (1) WO2009020932A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2229457A4 (en) 2007-12-14 2011-01-26 Minitube America Inc SEX-SPECIFIC SEPARATION OF SPERM AND EMBRYOES
WO2010085815A1 (en) * 2009-01-26 2010-07-29 Artemis Health, Inc. Methods and compositions for identifying a fetal cell
WO2011032034A2 (en) 2009-09-10 2011-03-17 University Of Idaho Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
WO2011073896A1 (en) * 2009-12-14 2011-06-23 Koninklijke Philips Electronics N.V. Novel tumor markers
WO2011073903A1 (en) * 2009-12-14 2011-06-23 Koninklijke Philips Electronics N.V. Novel tumor markers
JP5822913B2 (ja) * 2010-04-20 2015-11-25 ヴェンタナ メディカル システムズ, インク. 2色発色性インサイツハイブリダイゼーション
MX2014000797A (es) 2011-07-19 2014-07-09 Univ Idaho Sonda y metodo para direccionar acidos nucleicos.
CN103131709B (zh) * 2013-02-18 2014-12-17 石河子大学 zfx基因的RNA干扰片段及其控制小鼠性别的应用
JP2016528897A (ja) * 2013-08-16 2016-09-23 ラナ セラピューティクス インコーポレイテッド Rnaを調節するための組成物および方法
CN103642922A (zh) * 2013-12-10 2014-03-19 苏州九域星医疗科技有限公司 Pna检测母体血液中的循环胎儿dna的应用及方法
US10758558B2 (en) 2015-02-13 2020-09-01 Translate Bio Ma, Inc. Hybrid oligonucleotides and uses thereof
CN108823289B (zh) * 2018-06-08 2021-05-07 中国海洋大学 一种不依赖荧光检测杂交信号的鱼类染色体原位杂交液

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US5962332A (en) * 1994-03-17 1999-10-05 University Of Massachusetts Detection of trinucleotide repeats by in situ hybridization
EP1368369A4 (en) * 2000-11-15 2006-02-22 Hoffmann La Roche METHOD AND REAGENTS FOR IDENTIFYING RARE FOETAL CELLS IN THE MATERIAL CIRCUIT
DE10133308A1 (de) * 2001-07-12 2003-01-23 Praenadia Gmbh Verfahren zum Nachweis einer Nukleinsäure
AU2003243475A1 (en) * 2002-06-13 2003-12-31 New York University Early noninvasive prenatal test for aneuploidies and heritable conditions
US20070010657A1 (en) * 2002-09-13 2007-01-11 Rainer Klocke Cytoplasmic dynein heavy chain 1 genes, expression products, non-human animal model uses in human neurological diseases
JP2004187606A (ja) * 2002-12-12 2004-07-08 Institute Of Physical & Chemical Research 核酸アイソフォームの同定、分析および/またはクローニング方法
WO2005111235A2 (en) * 2004-05-04 2005-11-24 Dak Denmark A/S Methods for detecting chromosome aberrations

Also Published As

Publication number Publication date
JP2010535475A (ja) 2010-11-25
WO2009020932A2 (en) 2009-02-12
MX2010001380A (es) 2010-06-23
CA2695369A1 (en) 2009-02-12
US20110287415A1 (en) 2011-11-24
EP2173913A4 (en) 2010-09-01
EP2173913A2 (en) 2010-04-14
WO2009020932A3 (en) 2009-07-09
AU2008284024A1 (en) 2009-02-12
CN101809171A (zh) 2010-08-18
KR20100044878A (ko) 2010-04-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.