BRPI0812233A2 - Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos. - Google Patents

Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos.

Info

Publication number
BRPI0812233A2
BRPI0812233A2 BRPI0812233-4A2A BRPI0812233A BRPI0812233A2 BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2 BR PI0812233 A BRPI0812233 A BR PI0812233A BR PI0812233 A2 BRPI0812233 A2 BR PI0812233A2
Authority
BR
Brazil
Prior art keywords
euchariotic
organisms
methods
target dna
exact target
Prior art date
Application number
BRPI0812233-4A2A
Other languages
English (en)
Inventor
Anne Rolland
Manuel Dubald
Michiel Van Lookeren Campagne
Rene Ruiter
Original Assignee
Bayer Bioscience Nv
Bayer Cropscience Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Bioscience Nv, Bayer Cropscience Sa filed Critical Bayer Bioscience Nv
Publication of BRPI0812233A2 publication Critical patent/BRPI0812233A2/pt
Publication of BRPI0812233B1 publication Critical patent/BRPI0812233B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0812233-4A 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna BRPI0812233B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07010998 2007-06-05
EP07010998.8 2007-06-05
US93381407P 2007-06-08 2007-06-08
US60/933,814 2007-06-08
PCT/EP2008/004524 WO2008148559A1 (en) 2007-06-05 2008-06-03 Methods and means for exact replacement of target dna in eukaryotic organisms

Publications (2)

Publication Number Publication Date
BRPI0812233A2 true BRPI0812233A2 (pt) 2014-10-07
BRPI0812233B1 BRPI0812233B1 (pt) 2022-10-04

Family

ID=39673536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812233-4A BRPI0812233B1 (pt) 2007-06-05 2008-06-03 Processos para troca de uma sequência de dna-alvo no genoma de uma célula de planta ou planta por uma sequência de dna de interesse, e vetor de dna

Country Status (7)

Country Link
US (1) US8765448B2 (pt)
EP (1) EP2160467B1 (pt)
CN (1) CN101688217B (pt)
AU (1) AU2008258782B2 (pt)
BR (1) BRPI0812233B1 (pt)
CA (1) CA2689345C (pt)
WO (1) WO2008148559A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2568048A1 (en) 2007-06-29 2013-03-13 Pioneer Hi-Bred International, Inc. Methods for altering the genome of a monocot plant cell
WO2009114321A2 (en) 2008-03-11 2009-09-17 Precision Biosciencs, Inc. Rationally-designed meganucleases for maize genome engineering
EP2268129B1 (en) 2008-04-21 2015-06-17 Danziger Innovations Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
WO2011048600A1 (en) * 2009-10-21 2011-04-28 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
US9593317B2 (en) 2010-06-09 2017-03-14 Bayer Cropscience Nv Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering
CN109504700A (zh) 2010-06-09 2019-03-22 拜尔作物科学公司 植物基因组改造中常用的在核苷酸序列上修饰植物基因组的方法和工具
CN102559704B (zh) * 2010-12-23 2014-08-27 中国科学院上海生命科学研究院 一种在丙酮丁醇梭菌中敲除基因的方法
BR112013024337A2 (pt) * 2011-03-23 2017-09-26 Du Pont locus de traço transgênico complexo em uma planta, planta ou semente, método para produzir em uma planta um locus de traço transgênico complexo e construto de expressão
MX348785B (es) * 2011-06-06 2017-06-28 Bayer Cropscience Nv Metodos y medios para modificar un genoma vegetal en un sitio preseleccionado.
MX346439B (es) 2011-08-22 2017-03-17 Bayer Cropscience Nv Métodos y medios para modificar un genoma vegetal.
EP2612918A1 (en) 2012-01-06 2013-07-10 BASF Plant Science Company GmbH In planta recombination
CN104245940A (zh) * 2012-04-23 2014-12-24 拜尔作物科学公司 植物中的靶向基因组工程
WO2014161821A1 (en) 2013-04-02 2014-10-09 Bayer Cropscience Nv Targeted genome engineering in eukaryotes
WO2015034885A1 (en) 2013-09-04 2015-03-12 Dow Agrosciences Llc Rapid targeting analysis in crops for determining donor insertion
US10077449B2 (en) * 2013-11-04 2018-09-18 Dow Agrosciences Llc Universal donor system for gene targeting
RU2017112324A (ru) 2014-09-12 2018-10-15 Пайонир Хай-Бред Интернэшнл, Инк. Создание сайтов сайт-специфической интеграции для сложных локусов признаков в кукурузе и сое, а также способы применения
WO2016084084A1 (en) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Nucleic acid constructs for genome editing
WO2017102923A1 (en) 2015-12-15 2017-06-22 Bayer Cropscience Nv Brassicaceae plants resistant to plasmodiophora brassicae (clubroot)
US20190225974A1 (en) 2016-09-23 2019-07-25 BASF Agricultural Solutions Seed US LLC Targeted genome optimization in plants
EP4087600A4 (en) * 2020-01-09 2024-01-24 Pioneer Hi Bred Int TWO-STEP GENE EXCHANGE

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
CA2154581C (en) 1993-02-12 2008-12-16 Srinivasan Chandrasegaran Functional domains in flavobacterium okeanokoites (foki) restriction endonuclease
EP0790311A1 (en) 1996-02-16 1997-08-20 Centrum Voor Plantenveredelings- En Reproduktieonderzoek Microspore-specific promoter from tobacco
EP1147209A2 (en) 1999-02-03 2001-10-24 The Children's Medical Center Corporation Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site
DE10131786A1 (de) 2001-07-04 2003-01-16 Sungene Gmbh & Co Kgaa Rekombinationssysteme und Verfahren zum Entfernen von Nukleinsäuresequenzen aus dem Genom eukaryotischer Organismen
US20030232410A1 (en) 2002-03-21 2003-12-18 Monika Liljedahl Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
CN1253568C (zh) * 2002-09-02 2006-04-26 大连科源农业生物工程有限公司 具有生物安全性的植物基因工程操作方法
JP2006518372A (ja) 2003-01-28 2006-08-10 セレクティス 脊椎動物の体組織においてエクスビボかつイントトで相同的組換えを誘発するためのメガヌクレアーゼの使用およびその応用
WO2005049842A2 (en) * 2003-11-18 2005-06-02 Bayer Bioscience N.V. Improved targeted dna insertion in plants
CN101155921B (zh) 2005-04-04 2013-02-06 拜尔作物科学公司 用于去除所选择dna序列的方法和手段
EP2484758B1 (en) 2005-10-18 2013-10-02 Precision Biosciences Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinity
WO2007049095A1 (en) 2005-10-25 2007-05-03 Cellectis Laglidadg homing endonuclease variants having mutations in two functional subdomains and use thereof
WO2007060495A1 (en) 2005-10-25 2007-05-31 Cellectis I-crei homing endonuclease variants having novel cleavage specificity and use thereof
WO2007093836A1 (en) 2006-02-13 2007-08-23 Cellectis Meganuclease variants cleaving a dna target sequence from a xp gene and uses thereof
WO2008037436A1 (en) * 2006-09-28 2008-04-03 Bayer Bioscience N.V. Methods and means for removal of a selected dna sequence

Also Published As

Publication number Publication date
CA2689345C (en) 2017-07-11
AU2008258782B2 (en) 2013-09-19
CN101688217A (zh) 2010-03-31
EP2160467A1 (en) 2010-03-10
CN101688217B (zh) 2013-04-03
US8765448B2 (en) 2014-07-01
EP2160467B1 (en) 2015-10-28
US20100175143A1 (en) 2010-07-08
AU2008258782A1 (en) 2008-12-11
WO2008148559A1 (en) 2008-12-11
CA2689345A1 (en) 2008-12-11
BRPI0812233B1 (pt) 2022-10-04

Similar Documents

Publication Publication Date Title
BRPI0812233A2 (pt) Métodos e dispositivo para substituição exata de dna alvo em organismos eucarióticos.
BRPI0923159A2 (pt) gene de delta-endotoxina axmi-150 e métodos para sua utilização.
BRPI0813216A2 (pt) Inibidores de proteínas cinases e métodos para usá-los.
BRPI0815725A2 (pt) Métodos para detecção de oligonucleotídeos
BRPI0817292A2 (pt) Método e aparelho para completação de poços.
BRPI0814280A2 (pt) Ferramenta para formação de imagem de resistividade, e, método de formação de imagem de resistividade
BRPI0820556A2 (pt) Bactéria e métodos para uso das mesmas
BRPI0812448A2 (pt) Método para aperfeiçoamento de propriedades de proteína
BRPI0819842A2 (pt) Sistema de carga e método para operar o mesmo.
BRPI0910608A2 (pt) métodos e sistemas para avaliar resultados clínicos
BRPI0811883A2 (pt) Método e sistema para planejamento dentário.
BRPI0906327A2 (pt) Folha de registro e método para fabricar folha de registro.
BRPI0820212A2 (pt) Dispositivo para tratamento de fraturas, método para tratamento de fraturas, e, kit para tratamento de fraturas
BRPI0814077A2 (pt) Controlador e sistema e método para medir consumo de energia.
BRPI0716872A2 (pt) Fosfolipases, ácidos nucléicos codificando-as e métodos para fabricação e uso delas
BRPI0818011A2 (pt) Método e dispositivo para associar objetos
BRPI0819876A2 (pt) Sistema de enumeração e método para exibição de led.
BRPI0912426A2 (pt) método executado por computador, computador, e sistema para uso com poço
BRPI0923315A2 (pt) método sistema e utilização para comutação de calor.
BRPI0814988A2 (pt) Hidridização in-situ para detectar marcadores de rna e dna.
BRPI0913461A2 (pt) sistema e método para atuar seletivamente de uma localização remota múltiplas ferramentas de poço dentro do poço em um poço
BRPI1016243A2 (pt) agentes químicos e biológicos para o controle de moluscos.
BRPI0908734A2 (pt) Métodos para a identificação de dna genômico em uma amostra e para a indentificação de polimorfismos, e, kit
BRPI0811160A2 (pt) Aquecedor e método de operação
BRPI0812040A2 (pt) Indicações para terapia de anti-il-i-beta

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE S.A (FR) , BAYER CROPSCIENCE N.V

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER S.A.S. (FR)

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE N.V. (BE) , BAYER CROPSCIENCE AG

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/06/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE AG (DE) ; BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)

B25A Requested transfer of rights approved

Owner name: BASF AGRICULTURAL SOLUTIONS SEED US LLC (US)