BRPI0811320A2 - Surfactantes reconstituídos com propriedades melhoradas - Google Patents

Surfactantes reconstituídos com propriedades melhoradas

Info

Publication number
BRPI0811320A2
BRPI0811320A2 BRPI0811320-3A2A BRPI0811320A BRPI0811320A2 BR PI0811320 A2 BRPI0811320 A2 BR PI0811320A2 BR PI0811320 A BRPI0811320 A BR PI0811320A BR PI0811320 A2 BRPI0811320 A2 BR PI0811320A2
Authority
BR
Brazil
Prior art keywords
improved properties
directed
amino acid
reconstituted surfactants
polypeptide
Prior art date
Application number
BRPI0811320-3A2A
Other languages
English (en)
Inventor
Bengt Robertson
Tore Curstedt
Jan Johansson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of BRPI0811320A2 publication Critical patent/BRPI0811320A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
BRPI0811320-3A2A 2007-06-01 2008-05-22 Surfactantes reconstituídos com propriedades melhoradas BRPI0811320A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07010857A EP1997502A1 (en) 2007-06-01 2007-06-01 Reconstituted surfactants having improved properties
PCT/EP2008/004097 WO2008145298A1 (en) 2007-06-01 2008-05-22 Reconstituted surfactants having improved properties

Publications (1)

Publication Number Publication Date
BRPI0811320A2 true BRPI0811320A2 (pt) 2014-10-21

Family

ID=38421186

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811320-3A2A BRPI0811320A2 (pt) 2007-06-01 2008-05-22 Surfactantes reconstituídos com propriedades melhoradas

Country Status (14)

Country Link
US (1) US7897577B2 (pt)
EP (2) EP1997502A1 (pt)
JP (1) JP5575639B2 (pt)
KR (1) KR101516443B1 (pt)
CN (1) CN101687006B (pt)
AT (1) ATE544461T1 (pt)
AU (1) AU2008256449B2 (pt)
BR (1) BRPI0811320A2 (pt)
CA (1) CA2689066C (pt)
EA (1) EA017697B1 (pt)
HK (1) HK1140420A1 (pt)
MX (1) MX2009012675A (pt)
WO (1) WO2008145298A1 (pt)
ZA (1) ZA200908445B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CN103169947B (zh) * 2006-10-13 2014-10-29 奇斯药制品公司 具有改进性质的重组表面活性剂
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
WO2009049159A1 (en) * 2007-10-10 2009-04-16 Parion Sciences, Inc. Delivering osmolytes by nasal cannula
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
EP2717855A4 (en) 2011-06-07 2014-11-12 Parion Sciences Inc PROCESSING METHODS
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
EP2837377A1 (en) 2012-03-28 2015-02-18 Discovery Laboratories, Inc. Lyophilization of synthetic liposomal pulmonary surfactant
JP6272312B2 (ja) 2012-05-29 2018-01-31 パリオン・サイエンシィズ・インコーポレーテッド ドライアイおよび他の粘膜疾患の治療のためのナトリウムチャネル遮断活性を有するデンドリマー様アミノアミド
EP3428153A1 (en) 2012-12-17 2019-01-16 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
DK2931713T3 (en) 2012-12-17 2017-01-30 Parion Sciences Inc CHLORPYRAZINE CARBOXAMIDE DERIVATIVES USED FOR THE TREATMENT OF DISEASES BENEFITED BY INDEPENDENT MOSPHEREWIN
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
JP2017532981A (ja) 2014-10-01 2017-11-09 プラント ヘルス ケア インコーポレイテッド 破壊された過敏感反応ボックスを有するエリシターペプチド及びその使用
JP2017530197A (ja) 2014-10-01 2017-10-12 プラント ヘルス ケア インコーポレイテッド 過敏感反応エリシターペプチド及びその使用
CN108883148A (zh) 2016-04-06 2018-11-23 植物保健公司 过敏反应激发子来源的肽及其用途
WO2017176588A1 (en) 2016-04-06 2017-10-12 Plant Health Care, Inc. Beneficial microbes for delivery of effector peptides or proteins and use thereof
EP3558376B1 (en) 2016-12-22 2021-10-20 Chiesi Farmaceutici S.p.A. A therapeutic combination comprising a pulmonary surfactant and a steroid for the treatment of evolving bpd
AU2019260526A1 (en) 2018-04-23 2020-11-19 Chiesi Farmaceutici S.P.A. A therapeutic combination comprising a pulmonary surfactant and a steroid for the prophylaxis of BPD
US20230097886A1 (en) * 2021-07-30 2023-03-30 Ayuvis Research, Inc. Compositions and methods for the treatment of bronchopulmonary dysplasia (bpd) and bpd-associated pulmonary hypertension

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
IT1308180B1 (it) 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
AU5400000A (en) * 1999-06-11 2001-01-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
EP1558273B1 (en) * 2002-04-25 2011-08-17 The Scripps Research Institute Treatment and prevention of pulmonary conditions
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
CN103169947B (zh) * 2006-10-13 2014-10-29 奇斯药制品公司 具有改进性质的重组表面活性剂
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
ZA200908445B (en) 2011-02-23
MX2009012675A (es) 2009-12-14
EP2152288A1 (en) 2010-02-17
WO2008145298A1 (en) 2008-12-04
JP2010528997A (ja) 2010-08-26
US20090088379A1 (en) 2009-04-02
JP5575639B2 (ja) 2014-08-20
EA200901459A1 (ru) 2010-06-30
CN101687006B (zh) 2013-10-16
CN101687006A (zh) 2010-03-31
AU2008256449A1 (en) 2008-12-04
ATE544461T1 (de) 2012-02-15
KR20100015802A (ko) 2010-02-12
CA2689066C (en) 2016-03-29
EP2152288B1 (en) 2012-02-08
CA2689066A1 (en) 2008-12-04
US7897577B2 (en) 2011-03-01
EA017697B1 (ru) 2013-02-28
AU2008256449B2 (en) 2012-09-13
EP1997502A1 (en) 2008-12-03
HK1140420A1 (en) 2010-10-15
KR101516443B1 (ko) 2015-05-07

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]