ITMI20021058A1 - Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito - Google Patents

Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito

Info

Publication number
ITMI20021058A1
ITMI20021058A1 IT2002MI001058A ITMI20021058A ITMI20021058A1 IT MI20021058 A1 ITMI20021058 A1 IT MI20021058A1 IT 2002MI001058 A IT2002MI001058 A IT 2002MI001058A IT MI20021058 A ITMI20021058 A IT MI20021058A IT MI20021058 A1 ITMI20021058 A1 IT MI20021058A1
Authority
IT
Italy
Prior art keywords
mixtures
optimized
preparation
synthetic lipids
reconstituted surfactant
Prior art date
Application number
IT2002MI001058A
Other languages
English (en)
Inventor
Tore Curstedt
Jan Johansson
Bengt Robertson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Priority to IT2002MI001058A priority Critical patent/ITMI20021058A1/it
Publication of ITMI20021058A0 publication Critical patent/ITMI20021058A0/it
Priority to PCT/EP2003/004937 priority patent/WO2003097695A1/en
Priority to PT03727469T priority patent/PT1506234E/pt
Priority to DK03727469T priority patent/DK1506234T3/da
Priority to NZ536606A priority patent/NZ536606A/en
Priority to KR1020047018528A priority patent/KR101028927B1/ko
Priority to US10/512,869 priority patent/US7511011B2/en
Priority to SI200330756T priority patent/SI1506234T1/sl
Priority to PL372751A priority patent/PL209649B1/pl
Priority to JP2004506367A priority patent/JP4883906B2/ja
Priority to CNB038112531A priority patent/CN100347193C/zh
Priority to EA200401385A priority patent/EA007928B1/ru
Priority to AU2003233320A priority patent/AU2003233320B2/en
Priority to DE60311798T priority patent/DE60311798T2/de
Priority to EP03727469A priority patent/EP1506234B1/en
Priority to IL16523903A priority patent/IL165239A0/xx
Priority to AT03727469T priority patent/ATE353919T1/de
Priority to MXPA04011369A priority patent/MXPA04011369A/es
Priority to ES03727469T priority patent/ES2282627T3/es
Priority to CA2486152A priority patent/CA2486152C/en
Publication of ITMI20021058A1 publication Critical patent/ITMI20021058A1/it
Priority to UA20041109233A priority patent/UA79609C2/uk
Priority to TNP2004000219A priority patent/TNSN04219A1/en
Priority to HRP20041058AA priority patent/HRP20041058B1/hr
Priority to IL165239A priority patent/IL165239A/en
Priority to MA27946A priority patent/MA27960A1/fr
Priority to ZA200409215A priority patent/ZA200409215B/xx
Priority to HK05111361A priority patent/HK1079221A1/xx
Priority to CY20071100558T priority patent/CY1106667T1/el
Priority to US12/043,177 priority patent/US7842664B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
IT2002MI001058A 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito ITMI20021058A1 (it)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CA2486152A CA2486152C (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
EP03727469A EP1506234B1 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
AT03727469T ATE353919T1 (de) 2002-05-17 2003-05-12 Verbesserte mischungen synthetischer lipide zur herstellung einer rekonstituierten oberflächenaktiven substanz
IL16523903A IL165239A0 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
NZ536606A NZ536606A (en) 2002-05-17 2003-05-12 Reconstituted surfactants comprising the peptide SP-C in combination with dipalmitoyl phophatidylcholine, DPPC, and palmitoyl oleyl phosphatidylglycerol, POPG and/or POPC for treating respiratory distress syndrome
PT03727469T PT1506234E (pt) 2002-05-17 2003-05-12 Misturas de lípidos sintéticos melhoradas para a preparação de um surfactante reconstituído.
US10/512,869 US7511011B2 (en) 2002-05-17 2003-05-12 Synthetic lipid mixtures for the preparation of a reconstituted surfactant
SI200330756T SI1506234T1 (sl) 2002-05-17 2003-05-12 Izboljĺ ane zmesi sintetskih lipidov za pripravo rekonstituiranega surfaktanta
PL372751A PL209649B1 (pl) 2002-05-17 2003-05-12 Odtworzony surfaktant, sposób wytwarzania odtworzonego surfaktanta oraz jego zastosowanie
JP2004506367A JP4883906B2 (ja) 2002-05-17 2003-05-12 再構成サーファクタントの調製用の改善された合成脂質混合物
CNB038112531A CN100347193C (zh) 2002-05-17 2003-05-12 用于重构表面活性剂制备的改良的合成脂质混合物
EA200401385A EA007928B1 (ru) 2002-05-17 2003-05-12 Улучшенные синтетические липидные смеси для препарата синтетического сурфактанта
MXPA04011369A MXPA04011369A (es) 2002-05-17 2003-05-12 Mezclas lipidicas sinteticas mejoradas para la preparacion de un tensioactivo reconstituido.
DE60311798T DE60311798T2 (de) 2002-05-17 2003-05-12 Verbesserte mischungen synthetischer lipide zur herstellung einer rekonstituierten oberflächenaktiven substanz
PCT/EP2003/004937 WO2003097695A1 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
DK03727469T DK1506234T3 (da) 2002-05-17 2003-05-12 Forbedrede syntetiske lipidblandinger til fremstilling af et rekonstitueret tensid
KR1020047018528A KR101028927B1 (ko) 2002-05-17 2003-05-12 환원된 표면활성제의 제조를 위한 개선된 합성 지질 혼합체 및 그 제조방법
AU2003233320A AU2003233320B2 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
ES03727469T ES2282627T3 (es) 2002-05-17 2003-05-12 Mezclas de lipidos sinteticos mejoradas para la preparacion de un tensoactivo reconstituido.
UA20041109233A UA79609C2 (en) 2002-05-17 2003-12-05 Reproduced surface-active substance, process for the preparation thereof and uses in therapy
TNP2004000219A TNSN04219A1 (en) 2002-05-17 2004-11-11 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
HRP20041058AA HRP20041058B1 (hr) 2002-05-17 2004-11-12 Poboljšanje smjese sintetskih lipida za pripravke tenzida za ponovno uspostavljanje
IL165239A IL165239A (en) 2002-05-17 2004-11-16 Reconstituted surfactant comprising an artificial sp-c peptide analog and a phospholipid mixture, a process for its production and use thereof in the manufacture of medicaments for treating pulmonary dysfunction
MA27946A MA27960A1 (fr) 2002-05-17 2004-11-16 Melanges lipidiques synthetiques ameliores pour la preparation d'un tensioactif reconstitue.
ZA200409215A ZA200409215B (en) 2002-05-17 2004-11-17 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant.
HK05111361A HK1079221A1 (en) 2002-05-17 2005-12-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant
CY20071100558T CY1106667T1 (el) 2002-05-17 2007-04-26 Βελτιωμενα συνθετικα μιγματα λιπιδιων για την παρασκευη μιας ανασυγκροτημενης επιφανειοδραστικης ουσιας
US12/043,177 US7842664B2 (en) 2002-05-17 2008-03-06 Synthetic lipid mixtures for the preparation of a reconstituted surfactant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito

Publications (2)

Publication Number Publication Date
ITMI20021058A0 ITMI20021058A0 (it) 2002-05-17
ITMI20021058A1 true ITMI20021058A1 (it) 2003-11-17

Family

ID=11449919

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito

Country Status (27)

Country Link
US (2) US7511011B2 (it)
EP (1) EP1506234B1 (it)
JP (1) JP4883906B2 (it)
KR (1) KR101028927B1 (it)
CN (1) CN100347193C (it)
AT (1) ATE353919T1 (it)
AU (1) AU2003233320B2 (it)
CA (1) CA2486152C (it)
CY (1) CY1106667T1 (it)
DE (1) DE60311798T2 (it)
DK (1) DK1506234T3 (it)
EA (1) EA007928B1 (it)
ES (1) ES2282627T3 (it)
HK (1) HK1079221A1 (it)
HR (1) HRP20041058B1 (it)
IL (2) IL165239A0 (it)
IT (1) ITMI20021058A1 (it)
MA (1) MA27960A1 (it)
MX (1) MXPA04011369A (it)
NZ (1) NZ536606A (it)
PL (1) PL209649B1 (it)
PT (1) PT1506234E (it)
SI (1) SI1506234T1 (it)
TN (1) TNSN04219A1 (it)
UA (1) UA79609C2 (it)
WO (1) WO2003097695A1 (it)
ZA (1) ZA200409215B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
AU2004224807A1 (en) 2003-03-24 2004-10-07 Axikin Pharmaceuticals, Inc. 2-phenoxy- and 2-phenylsulfomamide derivatives with CCR3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
UA76074C2 (en) * 2005-11-09 2006-06-15 O V Palladin Inst Of Biochemis Calmophil, pharmaceutical composition for substitution therapy aimed at recovering malfunctioned surfactant system of lungs
PL2078038T3 (pl) * 2006-10-13 2014-05-30 Chiesi Farm Spa Rekonstytuowane środki powierzchniowo czynne o ulepszonych właściwościach
AU2008232677B2 (en) 2007-03-29 2013-09-19 National Jewish Health Surfactant lipids, compositions thereof, and uses thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
CA2720277C (en) 2008-04-02 2017-01-17 The University Of Tokushima Antigen-and-drug vehicle comprising synthetic peptide, and mucosal vaccine using the same
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
RU2013112562A (ru) * 2010-08-30 2014-10-10 Ф. Хоффманн-Ля Рош Аг Тетранектин-аполипопротеин а-i, содержащие его липидные частицы и его применение
MX2014001920A (es) 2011-08-25 2014-04-14 Hoffmann La Roche Proteina de fusion acortada de tetranectina-apolipoproteina a-i, una particula lipidica que la contiene, y usos de la misma.
CA2891933C (en) 2012-11-21 2022-07-05 Chiesi Farmaceutici S.P.A. Recombinant pulmonary surfactants comprising sp-b and sp-c analogues and a phospholipid mixture

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
AU2001245848A1 (en) * 2000-03-15 2001-10-23 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection
EP1276495B1 (en) 2000-04-12 2006-04-19 ALTANA Pharma AG Use of recombinant pulmonary surfactant for the early treatment of acute pulmonary diseases
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
DE60311798T2 (de) 2007-10-31
CA2486152A1 (en) 2003-11-27
CN100347193C (zh) 2007-11-07
TNSN04219A1 (en) 2007-03-12
US7842664B2 (en) 2010-11-30
AU2003233320B2 (en) 2008-06-19
KR20050016408A (ko) 2005-02-21
MXPA04011369A (es) 2005-02-17
JP4883906B2 (ja) 2012-02-22
HRP20041058B1 (hr) 2013-11-22
CN1653088A (zh) 2005-08-10
AU2003233320A2 (en) 2003-12-02
DK1506234T3 (da) 2007-06-11
EA007928B1 (ru) 2007-02-27
NZ536606A (en) 2006-10-27
UA79609C2 (en) 2007-07-10
PL372751A1 (en) 2005-08-08
KR101028927B1 (ko) 2011-04-12
DE60311798D1 (de) 2007-03-29
US20080242589A1 (en) 2008-10-02
EP1506234B1 (en) 2007-02-14
IL165239A0 (en) 2005-12-18
US20050176625A1 (en) 2005-08-11
WO2003097695A1 (en) 2003-11-27
ES2282627T3 (es) 2007-10-16
ITMI20021058A0 (it) 2002-05-17
CA2486152C (en) 2012-09-11
ZA200409215B (en) 2006-02-22
JP2006504635A (ja) 2006-02-09
CY1106667T1 (el) 2012-05-23
HRP20041058A2 (en) 2005-02-28
PT1506234E (pt) 2007-05-31
IL165239A (en) 2012-10-31
MA27960A1 (fr) 2006-07-03
EA200401385A1 (ru) 2005-08-25
SI1506234T1 (sl) 2007-06-30
AU2003233320A1 (en) 2003-12-02
ATE353919T1 (de) 2007-03-15
PL209649B1 (pl) 2011-09-30
HK1079221A1 (en) 2006-03-31
US7511011B2 (en) 2009-03-31
EP1506234A1 (en) 2005-02-16

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