BRPI0715893A2 - composto de azetidina e uso para a preparaÇço de um medicamento para a prevenÇço ou tratamento de distérbios distÍmicos ou do sono - Google Patents

composto de azetidina e uso para a preparaÇço de um medicamento para a prevenÇço ou tratamento de distérbios distÍmicos ou do sono

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Publication number
BRPI0715893A2
BRPI0715893A2 BRPI0715893-9A2A BRPI0715893A BRPI0715893A2 BR PI0715893 A2 BRPI0715893 A2 BR PI0715893A2 BR PI0715893 A BRPI0715893 A BR PI0715893A BR PI0715893 A2 BRPI0715893 A2 BR PI0715893A2
Authority
BR
Brazil
Prior art keywords
dysthymic
medicament
prevention
preparation
treatment
Prior art date
Application number
BRPI0715893-9A2A
Other languages
English (en)
Inventor
Hamed Aissaoui
Ralf Koberstein
Christoph Boss
Markus Gude
Thierry Sifferlen
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0715893A2 publication Critical patent/BRPI0715893A2/pt

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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems
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    • C08L19/006—Rubber characterised by functional groups, e.g. telechelic diene polymers
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    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
BRPI0715893-9A2A 2006-08-15 2007-08-15 composto de azetidina e uso para a preparaÇço de um medicamento para a prevenÇço ou tratamento de distérbios distÍmicos ou do sono BRPI0715893A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006052814 2006-08-15
PCT/IB2007/053244 WO2008020405A2 (en) 2006-08-15 2007-08-15 Azetidine compounds as orexin receptor antagonists

Publications (1)

Publication Number Publication Date
BRPI0715893A2 true BRPI0715893A2 (pt) 2013-09-17

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BRPI0715893-9A2A BRPI0715893A2 (pt) 2006-08-15 2007-08-15 composto de azetidina e uso para a preparaÇço de um medicamento para a prevenÇço ou tratamento de distérbios distÍmicos ou do sono

Country Status (15)

Country Link
US (1) US7994336B2 (pt)
EP (1) EP2069332B1 (pt)
JP (1) JP2010500401A (pt)
KR (1) KR101113626B1 (pt)
CN (1) CN101506199A (pt)
AT (1) ATE500250T1 (pt)
AU (1) AU2007285371A1 (pt)
BR (1) BRPI0715893A2 (pt)
CA (1) CA2659299A1 (pt)
DE (1) DE602007012910D1 (pt)
ES (1) ES2360376T3 (pt)
MX (1) MX2009001432A (pt)
PL (1) PL2069332T3 (pt)
RU (1) RU2447070C2 (pt)
WO (1) WO2008020405A2 (pt)

Families Citing this family (37)

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JP2010504957A (ja) * 2006-09-29 2010-02-18 アクテリオン ファーマシューティカルズ リミテッド ３−アザ−ビシクロ［３．１．０］ヘキサン誘導体
US8133901B2 (en) 2006-12-01 2012-03-13 Actelion Pharmaceuticals Ltd. 3-heteroaryl (amino or amido)-1-(biphenyl or phenylthiazolyl) carbonylpiperidine derivatives as orexin receptor inhibitors
CL2007003827A1 (es) * 2006-12-28 2008-09-26 Actelion Pharmaceuticals Ltd Compuestos derivados de n-(2-aza-biciclo(3.1.0)hex-3-ilmetil)amida; y su uso para prevenir o tratar la depresion, neurosis, esquizofrenia, ansiedad, adicciones, epilepsia, dolor, enfermedades cardiacas, entre otras.
CL2008000836A1 (es) * 2007-03-26 2008-11-07 Actelion Pharmaceuticals Ltd Compuestos derivados de tiazolidina, antagonistas del receptor de orexina; composicion farmaceutica que los comprende; y su uso en el tratamiento de neurosis emocional, depresion grave, trastornos psicoticos, alzheimer, parkinson, dolor, entre otras.
RU2470021C2 (ru) 2007-05-23 2012-12-20 Мерк Шарп Энд Домэ Корп. Пиридилпиперидиновые антагонисты рецептора орексинов
KR20100041805A (ko) * 2007-07-03 2010-04-22 액테리온 파마슈티칼 리미티드 3-아자-비시클로[3.3.0]옥탄 화합물
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JP2010540429A (ja) * 2007-09-24 2010-12-24 アクテリオン ファーマシューティカルズ リミテッド オレキシン受容体拮抗薬としてのピロリジン類及びピペリジン類
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ES2360376T3 (es) 2011-06-03
WO2008020405A3 (en) 2008-07-17
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RU2009109150A (ru) 2010-09-27
RU2447070C2 (ru) 2012-04-10
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MX2009001432A (es) 2009-02-17
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