BRPI0511330A - medição do grau de polimerização para sacarìdeos capsulares meningocócicos que contêm ácido siálico - Google Patents

medição do grau de polimerização para sacarìdeos capsulares meningocócicos que contêm ácido siálico

Info

Publication number
BRPI0511330A
BRPI0511330A BRPI0511330-0A BRPI0511330A BRPI0511330A BR PI0511330 A BRPI0511330 A BR PI0511330A BR PI0511330 A BRPI0511330 A BR PI0511330A BR PI0511330 A BRPI0511330 A BR PI0511330A
Authority
BR
Brazil
Prior art keywords
sialic acid
measurement
polymerization degree
capsular saccharides
saccharides
Prior art date
Application number
BRPI0511330-0A
Other languages
English (en)
Inventor
Angela Bardotti
Original Assignee
Chiron Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Srl filed Critical Chiron Srl
Publication of BRPI0511330A publication Critical patent/BRPI0511330A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MEDIçãO DO GRAU DE POLIMERIZAçãO PARA SACARìDEOS CAPSULARES MENINGOCóCICOS QUE CONTéM áCIDO SIáLICO. O grau de polimerização (DP) é um parâmetro importante para análise de antígenos de sacarídeo, particularmente em glicoconjugados. A invenção proporciona métodos que podem ser usados para medir o DP de sacarídeos capsulares, particularmente sacarídeos meningocócicos, por exemplo, dos sorogrupos W135 e Y. Um método preferido é baseado em redução dos resíduos de ácido siálico terminais sobre os sacarídeos, com o DP, então, sendo calculado através de comparação da proporção molar de ácido siálico total para ácido siálico reduzido.
BRPI0511330-0A 2004-05-21 2005-05-23 medição do grau de polimerização para sacarìdeos capsulares meningocócicos que contêm ácido siálico BRPI0511330A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0411387.4A GB0411387D0 (en) 2004-05-21 2004-05-21 Analysis of saccharide length
PCT/IB2005/002264 WO2005113607A2 (en) 2004-05-21 2005-05-23 Measuring degree of polymerisation for capsular saccharides that contain sialic acid

Publications (1)

Publication Number Publication Date
BRPI0511330A true BRPI0511330A (pt) 2007-12-04

Family

ID=32607749

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511330-0A BRPI0511330A (pt) 2004-05-21 2005-05-23 medição do grau de polimerização para sacarìdeos capsulares meningocócicos que contêm ácido siálico

Country Status (12)

Country Link
US (2) US7803583B2 (pt)
EP (2) EP1769005A2 (pt)
JP (1) JP4963672B2 (pt)
CN (1) CN101039962B (pt)
AU (1) AU2005245689B2 (pt)
BR (1) BRPI0511330A (pt)
CA (1) CA2567486C (pt)
GB (1) GB0411387D0 (pt)
MX (1) MXPA06013472A (pt)
NZ (1) NZ551528A (pt)
RU (1) RU2401279C2 (pt)
WO (1) WO2005113607A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
JP5815203B2 (ja) * 2009-06-23 2015-11-17 コンビ株式会社 コラーゲン産生低下抑制剤、それを含む皮膚外用組成物および化粧料
JP5815202B2 (ja) * 2009-06-23 2015-11-17 コンビ株式会社 コラーゲン産生促進剤、それを含む皮膚外用組成物および化粧料
CN101928353B (zh) * 2010-08-13 2012-07-18 内蒙古昆明卷烟有限责任公司 冬虫夏草多糖的提取及其在卷烟中的应用
HRP20210242T4 (hr) 2010-08-23 2024-05-10 Wyeth Llc Stabilne formulacije antigena iz bakterije neisseria meningitidis rlp2086
CN103096920B (zh) 2010-09-10 2016-03-23 惠氏有限责任公司 脑膜炎奈瑟球菌orf2086抗原的非脂质化变体
CN102608046B (zh) * 2012-03-05 2014-07-09 熊鹏 简易的低聚木糖平均聚合度的测定方法
BR122016004924A2 (pt) 2012-03-09 2019-07-30 Pfizer Inc. Polipeptídeo isolado e composições imunogênicas compreendendo os mesmos
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CN102645504B (zh) * 2012-05-10 2014-04-30 江南大学 一种灵芝孢子粉多糖离子色谱指纹图谱的构建方法
CA2896552A1 (en) 2012-10-03 2014-04-10 Novartis Ag Immunogenic compositions
JP6446377B2 (ja) 2013-03-08 2018-12-26 ファイザー・インク 免疫原性融合ポリペプチド
CA2923129C (en) 2013-09-08 2020-06-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
JP5914576B2 (ja) * 2014-06-09 2016-05-11 コンビ株式会社 コラーゲン産生促進剤、それを含む皮膚外用組成物および化粧料
JP5914577B2 (ja) * 2014-06-09 2016-05-11 コンビ株式会社 コラーゲン産生低下抑制剤、それを含む皮膚外用組成物および化粧料
AU2016221318B2 (en) 2015-02-19 2020-06-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
EP3292146A1 (en) 2015-05-04 2018-03-14 Pfizer Inc Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CA3079837A1 (en) * 2017-11-01 2019-05-09 The Board Of Trustees Of The Leland Stanford Junior University Analyte detection method

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057685A (en) 1972-02-02 1977-11-08 Abbott Laboratories Chemically modified endotoxin immunizing agent
US4356170A (en) 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4459286A (en) 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
US4663160A (en) 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4761283A (en) 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4808700A (en) 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
JPH01125328A (ja) 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
NL8802046A (nl) 1988-08-18 1990-03-16 Gen Electric Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
DE3841091A1 (de) 1988-12-07 1990-06-13 Behringwerke Ag Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
DE68907045T2 (de) 1989-01-17 1993-12-02 Eniricerche Spa Synthetische Peptide und deren Verwendung als allgemeine Träger für die Herstellung von immunogenischen Konjugaten, die für die Entwicklung von synthetischen Impfstoffen geeignet sind.
CA2063271A1 (en) 1989-07-14 1991-01-15 Subramonia Pillai Cytokine and hormone carriers for conjugate vaccines
IT1237764B (it) 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
EP0462794B1 (en) * 1990-06-21 1998-09-09 Oxford GlycoSciences (UK) Limited Automated process equipment for cleavage of biomolecules
DE69113564T2 (de) 1990-08-13 1996-05-30 American Cyanamid Co Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
US5153312A (en) 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
IT1262896B (it) 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
IL102687A (en) 1992-07-30 1997-06-10 Yeda Res & Dev Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
JP4233113B2 (ja) 1995-06-07 2009-03-04 グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン
US6299881B1 (en) 1997-03-24 2001-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
GB9713156D0 (en) 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
US7018637B2 (en) 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
JP2004505885A (ja) 1998-08-19 2004-02-26 ノース アメリカン ワクチン, インコーポレイテッド N−アクリロイル化ポリサッカリドを用いて産生されたワクチンとして有用な免疫原性β−プロピオンアミド連結ポリサッカリド−タンパク質結合体
JP4846906B2 (ja) 1999-03-19 2011-12-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
CA2365914A1 (en) 1999-04-09 2000-10-19 Techlab, Inc. Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
ES2507100T3 (es) 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
GB0007432D0 (en) 2000-03-27 2000-05-17 Microbiological Res Authority Proteins for use as carriers in conjugate vaccines
US6936261B2 (en) 2000-07-27 2005-08-30 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
GB0103170D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
AU2002309706A1 (en) 2001-05-11 2002-11-25 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
US20040214228A9 (en) * 2001-09-14 2004-10-28 Ganesh Venkataraman Methods of evaluating glycomolecules for enhanced activities
DK1777236T3 (en) * 2002-03-26 2017-02-27 Glaxosmithkline Biologicals Sa MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0406013D0 (en) * 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference

Also Published As

Publication number Publication date
RU2006145335A (ru) 2008-06-27
MXPA06013472A (es) 2007-03-01
AU2005245689A1 (en) 2005-12-01
CA2567486A1 (en) 2005-12-01
US8790893B2 (en) 2014-07-29
WO2005113607A3 (en) 2006-04-13
JP4963672B2 (ja) 2012-06-27
CN101039962B (zh) 2011-05-04
AU2005245689B2 (en) 2012-05-24
US20080274135A1 (en) 2008-11-06
NZ551528A (en) 2011-01-28
EP2267035A2 (en) 2010-12-29
CA2567486C (en) 2016-01-19
WO2005113607A2 (en) 2005-12-01
US7803583B2 (en) 2010-09-28
GB0411387D0 (en) 2004-06-23
US20110159029A1 (en) 2011-06-30
JP2008500384A (ja) 2008-01-10
CN101039962A (zh) 2007-09-19
EP1769005A2 (en) 2007-04-04
EP2267035A3 (en) 2011-03-02
RU2401279C2 (ru) 2010-10-10

Similar Documents

Publication Publication Date Title
BRPI0511330A (pt) medição do grau de polimerização para sacarìdeos capsulares meningocócicos que contêm ácido siálico
Berti et al. Relative stability of meningococcal serogroup A and X polysaccharides
NO20080334L (no) Metode for a fremstille en kapasitiv akselerasjonssensor, og kapasitiv akselerasjonssensor
WO2006000920A3 (en) Dimensional analysis of saccharide conjugates with gpc & sec-mals
BR0310062A (pt) Vacinas mucosas com adjuvante de quitosana e/ou antìgenos meningocócicos
AR072258A1 (es) Conjunto de elementos y metodos para dejar de fumar. usos. agente. composicion inmunogenica.
Lyles et al. Correlating two viral load assays with known detection limits
BR112012031375A2 (pt) sistema de gerenciamento de enchimento abaixo do necessário para um biosensor
BRPI0806549B8 (pt) sistema para testar drogas de abuso e processo para determinar a presença ou ausência de uma droga de abuso
BR0311730A (pt) Método para determinação da composição de um fluido do furo abaixo
BR112013013464A2 (pt) método para medir pelo menos uma propriedade de uma amostra predominantemente líquida
ATE205614T1 (de) Parallele prüfung eines cpu-cachespeichers sowie befehlseinheit
US20120009686A1 (en) Method of measuring the concentration of a glycosaminoglycan anticoagulant
Scherrer et al. Effect of water exposure on the fracture toughness and flexure strength of a dental glass
Gottlieb et al. Experimental tests of entanglement models of rubber elasticity. 3. Biaxial deformations
NO20083133L (no) Dobbel transdermal analyttsensorsammensetning samt metoder for anvendelse derav
Kirby et al. Sample size estimation using repeated measurements on biomarkers as outcomes
KR930703612A (ko) 항-알엔에이(rna) 항체의 검출 방법
DE60217300D1 (de) Verfahren zur untersuchung der wirkung eines angionegesis-hemmers unter vermittlung durch hemmung der integrin-expression
WO2007136848A3 (en) Interactive device for monitoring and reporting glucose levels
Ahmed et al. Comparison of orthodontic bracket debonding force and bracket failure pattern on different teeth in vivo by a prototype debonding device
Kier et al. Reliability and validity of scores on the Personal Preferences Self-Description Questionnaire (PPSDQ)
Ismail On the interpretation of affirmative follow-up tests in immunoassays: what must not be done?
Waites et al. Revaccination of adults with spinal cord injury using the 23-valent pneumococcal polysaccharide vaccine
CN101140276A (zh) 肺炎结合疫苗原液中结合物含量的测定方法

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]