BRPI0412131A - métodos de tratamento de distúrbios oftálmicos, para evitar hemorragia retìnica, perda de acuidade visual, reduzir exsudatos duros e retardar progressão de dano retìnico - Google Patents

métodos de tratamento de distúrbios oftálmicos, para evitar hemorragia retìnica, perda de acuidade visual, reduzir exsudatos duros e retardar progressão de dano retìnico

Info

Publication number
BRPI0412131A
BRPI0412131A BRPI0412131-7A BRPI0412131A BRPI0412131A BR PI0412131 A BRPI0412131 A BR PI0412131A BR PI0412131 A BRPI0412131 A BR PI0412131A BR PI0412131 A BRPI0412131 A BR PI0412131A
Authority
BR
Brazil
Prior art keywords
retinal
methods
ophthalmic disorders
loss
visual acuity
Prior art date
Application number
BRPI0412131-7A
Other languages
English (en)
Inventor
Stephen P Bartels
Sebastiano Mangiafico
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of BRPI0412131A publication Critical patent/BRPI0412131A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)

Abstract

"MéTODOS DE TRATAMENTO DE DISTúRBIOS OFTáLMICOS, PARA EVITAR HEMORRAGIA RETìNICA, PEDRA DE ACUIDADE VISUAL, REDUZIR EXSUDATOS DUROS, E RETARDAR PROGRESSãO DE DANO RETìNICO". Composições farmacêuticas que compreendem bases de cumarina e os seus sais são de utilidade para tratar vários distúrbios oftálmicos. O ingrediente ativo inclui cloricromeno ou seu sal de cloridrato.
BRPI0412131-7A 2003-06-30 2004-06-28 métodos de tratamento de distúrbios oftálmicos, para evitar hemorragia retìnica, perda de acuidade visual, reduzir exsudatos duros e retardar progressão de dano retìnico BRPI0412131A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48370403P 2003-06-30 2003-06-30
PCT/US2004/020739 WO2005004859A1 (en) 2003-06-30 2004-06-28 Coumarin derivatives for the treatment of ophthalmic disorders

Publications (1)

Publication Number Publication Date
BRPI0412131A true BRPI0412131A (pt) 2006-08-15

Family

ID=34061975

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412131-7A BRPI0412131A (pt) 2003-06-30 2004-06-28 métodos de tratamento de distúrbios oftálmicos, para evitar hemorragia retìnica, perda de acuidade visual, reduzir exsudatos duros e retardar progressão de dano retìnico

Country Status (11)

Country Link
US (1) US20050054586A1 (pt)
EP (1) EP1638550A1 (pt)
JP (1) JP2007521285A (pt)
KR (1) KR20060026901A (pt)
CN (1) CN1870989A (pt)
AU (1) AU2004255199A1 (pt)
BR (1) BRPI0412131A (pt)
CA (1) CA2528148A1 (pt)
MX (1) MXPA05014143A (pt)
WO (1) WO2005004859A1 (pt)
ZA (1) ZA200510344B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR059339A1 (es) 2006-02-09 2008-03-26 Chugai Pharmaceutical Co Ltd Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene
US20080103103A1 (en) * 2006-10-30 2008-05-01 Bahram Memarzadeh Reagents and methods to treat ocular diseases and infection
WO2009014100A1 (ja) 2007-07-20 2009-01-29 Chugai Seiyaku Kabushiki Kaisha ｐ２７蛋白質誘導剤
RU2362554C2 (ru) * 2007-09-27 2009-07-27 Екатерина Валентиновна Лопатина Регенерирующее противовоспалительное средство и способы лечения с помощью этого средства
CN102190645B (zh) * 2010-03-18 2014-03-05 上海中医药大学 蛇床子素衍生物及其制备方法和在制备抗乳腺癌药物中的应用
EP3133066A1 (en) 2015-08-21 2017-02-22 Merck Patent GmbH Hydrophilic compounds for optically active devices
EP3133065A1 (en) * 2015-08-21 2017-02-22 Merck Patent GmbH Compounds for optically active devices
EP3363793A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Hydrophobic compounds for optically active devices
EP3363786A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Compounds for optically active devices

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259635A (en) * 1962-07-26 1966-07-05 Cassella Farbwerke Mainkur Ag 7-hydroxy coumarin derivative
US3515721A (en) * 1967-06-26 1970-06-02 Cassella Farbwerke Mainkur Ag 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
IT1160365B (it) * 1978-12-19 1987-03-11 F I D I A Spa Applicazioni in campo farmacologico e terapeutico dell'8-cloro-3-(beta-dietilamincetil)-4-metil-7-etossi-carbonilmetossicumarina cloridrato preparato allo stato puro mediante procedimento selettivo, con particolare riguardo alla sua azione antiaritmica
IT1160366B (it) * 1978-12-19 1987-03-11 F I D I A Spa Applicazioni in campo farmacologico e terapeutico dell'8-cloro-3(beta-dietilamincetil)-4-metil-7-etossi-carbonilmetossi cumarina cloridrato preparato allo stato puro con procedimento selettivo con particolare riguardo alla sua attivita' anti-aggregante piastrinica
US4210667A (en) * 1979-04-19 1980-07-01 Pfizer Inc. Pharmaceutical preparations containing coumarin carboxylic acid derivatives
IT1212907B (it) * 1983-12-21 1989-11-30 Romeo Aurelio Preparazione di fenoli alogenati
FI873428A (fi) * 1986-08-18 1988-02-19 Houston Biotechnology Oftalmologiska kompositioner foer behandling av nervdegenerationer.
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US6242198B1 (en) * 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
IT1306669B1 (it) * 1999-06-14 2001-10-02 Fidia Spa Composizioni farmaceutiche comprendenti 8-cloro-3 (beta-dietilaminoetil) -4-metil-7-etossicarbonilmetossi cumarina base e
US6331313B1 (en) * 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6375972B1 (en) * 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
IT1317356B1 (it) * 2000-07-31 2003-06-16 Fidia S P A Ora Fidia Farmaceu Derivati della cumarina e relativi sali, processo per la loropreparazione e loro impiego in campo farmaceutico.
JP2004517674A (ja) * 2000-12-29 2004-06-17 ボシュ・アンド・ロム・インコーポレイテッド 徐放薬物送達装置
EP1347742A1 (en) * 2001-01-03 2003-10-01 Bausch & Lomb Incorporated Sustained release drug delivery devices with prefabricated permeable plugs
ES2294043T3 (es) * 2001-01-03 2008-04-01 BAUSCH & LOMB INCORPORATED Dispositivos de liberacion prolongada de medicamentos que comprenden nucleos recubiertos de medicamentos.
US6756058B2 (en) * 2001-01-03 2004-06-29 Bausch & Lomb Incorporated Sustained release drug delivery devices with multiple agents
CA2433528A1 (en) * 2001-01-26 2002-08-01 Bausch & Lomb Incorporated Improved process for the production of sustained release drug delivery devices
WO2002066454A1 (en) * 2001-02-21 2002-08-29 Sankyo Company, Limited Chromene derivatives

Also Published As

Publication number Publication date
AU2004255199A1 (en) 2005-01-20
US20050054586A1 (en) 2005-03-10
JP2007521285A (ja) 2007-08-02
CA2528148A1 (en) 2005-01-20
EP1638550A1 (en) 2006-03-29
MXPA05014143A (es) 2006-02-24
CN1870989A (zh) 2006-11-29
WO2005004859A1 (en) 2005-01-20
ZA200510344B (en) 2006-12-27
KR20060026901A (ko) 2006-03-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.