BRPI0409230A - formas de dosagem compreendendo ag013736 - Google Patents

formas de dosagem compreendendo ag013736

Info

Publication number
BRPI0409230A
BRPI0409230A BRPI0409230-9A BRPI0409230A BRPI0409230A BR PI0409230 A BRPI0409230 A BR PI0409230A BR PI0409230 A BRPI0409230 A BR PI0409230A BR PI0409230 A BRPI0409230 A BR PI0409230A
Authority
BR
Brazil
Prior art keywords
dosage forms
prodrugs
solvates
mammal
cancer
Prior art date
Application number
BRPI0409230-9A
Other languages
English (en)
Inventor
James Lawrence Freddo
Dana Hu-Lowe
Yazdi Kersi Pithavala
Heidi Marie Steinfeldt
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0409230A publication Critical patent/BRPI0409230A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

"FORMAS DE DOSAGEM COMPREENDENDO AG013736". A invenção refere-se a formas de dosagem de um composto de fórmula (1) ou seus sais, solvatos ou pró-fármacos farmaceuticamente aceitáveis. Adicionalmente, a invenção proporciona métodos de tratamento do crescimento celular anormal, tal como câncer, pela administração de formas de dosagem a um mamífero.
BRPI0409230-9A 2003-04-03 2004-03-17 formas de dosagem compreendendo ag013736 BRPI0409230A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46069503P 2003-04-03 2003-04-03
US49177103P 2003-07-31 2003-07-31
PCT/IB2004/000867 WO2004087152A1 (en) 2003-04-03 2004-03-17 Dosage forms comprising ag013736

Publications (1)

Publication Number Publication Date
BRPI0409230A true BRPI0409230A (pt) 2006-03-28

Family

ID=33135143

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409230-9A BRPI0409230A (pt) 2003-04-03 2004-03-17 formas de dosagem compreendendo ag013736

Country Status (16)

Country Link
US (1) US20040224988A1 (pt)
EP (1) EP1613320A1 (pt)
JP (1) JP2006522087A (pt)
KR (1) KR20050119671A (pt)
AR (1) AR043822A1 (pt)
AU (1) AU2004226586B2 (pt)
BR (1) BRPI0409230A (pt)
CA (1) CA2520932A1 (pt)
MX (1) MXPA05009303A (pt)
NL (1) NL1025873C2 (pt)
NO (1) NO20055143L (pt)
PA (1) PA8599701A1 (pt)
RU (2) RU2341263C2 (pt)
TW (1) TW200423933A (pt)
UY (1) UY28255A1 (pt)
WO (1) WO2004087152A1 (pt)

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CN101052633A (zh) * 2004-11-02 2007-10-10 辉瑞大药厂 制备吲唑化合物的方法
CA2586174A1 (en) * 2004-11-02 2006-05-11 Brigitte Leigh Ewanicki Methods of preparing indazole compounds
PT1866339E (pt) 2005-03-25 2013-09-03 Gitr Inc Moléculas de ligação a gitr e suas utilizações
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP4074702A1 (en) 2007-04-05 2022-10-19 Pfizer Products Inc. Crystalline forms of 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-e-[2-(pyridin-2-yl)ethenyl]indazole suitable for the treatment of abnormal cell growth in mammals
WO2009009116A2 (en) * 2007-07-12 2009-01-15 Tolerx, Inc. Combination therapies employing gitr binding molecules
KR20110036101A (ko) 2008-06-30 2011-04-06 안지오블라스트 시스템스 인코퍼레이티드 조합된 치료를 사용한 안과질환 및 과도한 혈관신생의 치료
KR20140069297A (ko) 2011-09-30 2014-06-09 화이자 인코포레이티드 N-메틸-2-[3-((e)-2-피리딘-2-일-비닐)-1h-인다졸-6-일-설파닐]-벤즈아미드의 약학 조성물
WO2013068909A1 (en) 2011-11-11 2013-05-16 Pfizer Inc. N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia
EP2792360A1 (en) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV
EP3971209A1 (en) 2014-02-04 2022-03-23 Pfizer Inc. Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer
JP6414727B2 (ja) * 2014-04-01 2018-10-31 公益財団法人ヒューマンサイエンス振興財団 関節疾患の治療予防剤
CN104013589A (zh) * 2014-05-07 2014-09-03 万特制药(海南)有限公司 一种阿西替尼口腔崩解片及其制备方法
CA2955676A1 (en) 2014-08-25 2016-03-03 Pfizer Inc. Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
CN107405401B (zh) 2015-02-26 2022-02-01 默克专利股份公司 用于治疗癌症的pd-1/pd-l1抑制剂
EP3310810A1 (en) 2015-06-16 2018-04-25 Merck Patent GmbH Pd-l1 antagonist combination treatments
CA3012718A1 (en) 2016-02-08 2017-08-17 Vitrisa Therapeutics, Inc. Compositions with improved intravitreal half-life and uses thereof
CN109843324A (zh) 2016-10-06 2019-06-04 辉瑞公司 用于治疗癌症的avelumab用药方案
US20220370606A1 (en) 2018-12-21 2022-11-24 Pfizer Inc. Combination Treatments Of Cancer Comprising A TLR Agonist
WO2023166420A1 (en) 2022-03-03 2023-09-07 Pfizer Inc. Multispecific antibodies and uses thereof

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US5587458A (en) * 1991-10-07 1996-12-24 Aronex Pharmaceuticals, Inc. Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
EP0625200B1 (en) * 1992-02-06 2005-05-11 Chiron Corporation Biosynthetic binding protein for cancer marker
US5339184A (en) * 1992-06-15 1994-08-16 Gte Laboratories Incorporated Fiber optic antenna remoting for multi-sector cell sites
US5459607A (en) * 1993-04-19 1995-10-17 C-Cor/Comlux, Inc. Synchronous optical digital transmission system and method
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US5747498A (en) * 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
JP3588984B2 (ja) * 1997-08-20 2004-11-17 Ｋｄｄｉ株式会社 光パワー計測システム並びにそのための端局及び中継器
GB2332603B (en) * 1997-12-22 2000-07-19 Lsi Logic Corp Improvements relating to multidirectional communication systems
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TWI262914B (en) * 1999-07-02 2006-10-01 Agouron Pharma Compounds and pharmaceutical compositions for inhibiting protein kinases
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Also Published As

Publication number Publication date
RU2005128791A (ru) 2006-05-10
AR043822A1 (es) 2005-08-17
WO2004087152A1 (en) 2004-10-14
MXPA05009303A (es) 2005-10-05
NO20055143L (no) 2006-01-03
JP2006522087A (ja) 2006-09-28
CA2520932A1 (en) 2004-10-14
AU2004226586A1 (en) 2004-10-14
RU2008122358A (ru) 2009-12-10
TW200423933A (en) 2004-11-16
NO20055143D0 (no) 2005-11-02
UY28255A1 (es) 2004-11-30
NL1025873C2 (nl) 2006-02-14
PA8599701A1 (es) 2004-11-26
NL1025873A1 (nl) 2004-10-05
AU2004226586B2 (en) 2008-12-11
EP1613320A1 (en) 2006-01-11
RU2341263C2 (ru) 2008-12-20
US20040224988A1 (en) 2004-11-11
KR20050119671A (ko) 2005-12-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.