BR9806145A - Processo para derivatização seletiva de taxanos - Google Patents

Processo para derivatização seletiva de taxanos

Info

Publication number
BR9806145A
BR9806145A BR9806145-3A BR9806145A BR9806145A BR 9806145 A BR9806145 A BR 9806145A BR 9806145 A BR9806145 A BR 9806145A BR 9806145 A BR9806145 A BR 9806145A
Authority
BR
Brazil
Prior art keywords
taxanes
selective derivatization
dab
hydroxyl group
derivatized
Prior art date
Application number
BR9806145-3A
Other languages
English (en)
Inventor
Robert A Holton
Zhuming Zhang
Paul A Clark
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27368950&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9806145(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Florida State filed Critical Univ Florida State
Publication of BR9806145A publication Critical patent/BR9806145A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fats And Perfumes (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Soil Working Implements (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA DERIVATIZAçãO SELETIVA DE TAXANOS"<D>. Processo para a preparação de taxol e outros taxanos através de derivatização seletiva de grupos hidroxila C(7) e C(10) de 10-DAB, particularmente um novo processo usando uma nova estratégia em que o grupo hidroxila C(10) é protegido ou derivatizado antes do grupo hidroxila C(7), e a provisão de compostos 10-DAB derivatizados C(7) e C(10).
BR9806145-3A 1997-08-18 1998-08-17 Processo para derivatização seletiva de taxanos BR9806145A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5600097P 1997-08-18 1997-08-18
US8126598P 1998-04-09 1998-04-09
US09/063,477 US7288665B1 (en) 1997-08-18 1998-04-20 Process for selective derivatization of taxanes
PCT/US1998/017016 WO1999009021A1 (en) 1997-08-18 1998-08-17 Process for selective derivatization of taxanes

Publications (1)

Publication Number Publication Date
BR9806145A true BR9806145A (pt) 2000-01-18

Family

ID=27368950

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9806145-3A BR9806145A (pt) 1997-08-18 1998-08-17 Processo para derivatização seletiva de taxanos

Country Status (25)

Country Link
US (5) US7288665B1 (pt)
EP (6) EP1170292B1 (pt)
JP (1) JP2001504864A (pt)
KR (1) KR100596989B1 (pt)
CN (3) CN1974563A (pt)
AT (3) ATE326455T1 (pt)
AU (1) AU744987B2 (pt)
BR (1) BR9806145A (pt)
CA (2) CA2597799A1 (pt)
CY (1) CY1105399T1 (pt)
CZ (1) CZ296580B6 (pt)
DE (3) DE69834584T2 (pt)
DK (3) DK1170292T3 (pt)
ES (3) ES2274579T3 (pt)
HU (1) HUP0300425A3 (pt)
ID (1) ID21654A (pt)
IL (3) IL129386A0 (pt)
NO (4) NO325139B1 (pt)
NZ (1) NZ335156A (pt)
PL (3) PL332723A1 (pt)
PT (3) PT1170293E (pt)
RU (1) RU2225402C2 (pt)
SG (1) SG97986A1 (pt)
WO (1) WO1999009021A1 (pt)
ZA (1) ZA987394B (pt)

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NO325139B1 (no) 2008-02-11
PT956284E (pt) 2006-12-29
PT1170293E (pt) 2006-07-31
CA2597799A1 (en) 1999-02-25
ID21654A (id) 1999-07-08
CA2268662A1 (en) 1999-02-25
CN1690053A (zh) 2005-11-02
CN1974563A (zh) 2007-06-06
DE69834584D1 (de) 2006-06-22
JP2001504864A (ja) 2001-04-10
DE69836072D1 (de) 2006-11-16
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EP1170292A2 (en) 2002-01-09
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EP1193262A1 (en) 2002-04-03
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US6191287B1 (en) 2001-02-20
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US6291691B1 (en) 2001-09-18
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CN1239476A (zh) 1999-12-22
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