BR9800426A - Processo para fabricação de derivados de benzofenona - Google Patents

Processo para fabricação de derivados de benzofenona

Info

Publication number
BR9800426A
BR9800426A BR9800426-3A BR9800426A BR9800426A BR 9800426 A BR9800426 A BR 9800426A BR 9800426 A BR9800426 A BR 9800426A BR 9800426 A BR9800426 A BR 9800426A
Authority
BR
Brazil
Prior art keywords
benzophenone derivatives
manufacturing
formula
compounds
benzophenone
Prior art date
Application number
BR9800426-3A
Other languages
English (en)
Other versions
BR9800426B1 (pt
Inventor
Juerg Bruhin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR9800426A publication Critical patent/BR9800426A/pt
Publication of BR9800426B1 publication Critical patent/BR9800426B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/16—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/784—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with all keto groups bound to a non-condensed ring
    • C07C49/786—Benzophenone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção:<B>"PROCESSO PARA FABRICAçãO DE DERIVADOS DE BENZOFENONA"<D>. A presente invenção refere-se a um processo para a fabricação de derivados da benzofenona e baseia-se na separação de compostos da fórmula (I) a partir de compostos isoméricos correspondentes da fórmula (II), pela cristalização seletiva de sais correspondentes de compostos de fórmula (I).
BRPI9800426-3A 1997-01-22 1998-01-21 processo para fabricação de derivados de benzofenona. BR9800426B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97100930 1997-01-22

Publications (2)

Publication Number Publication Date
BR9800426A true BR9800426A (pt) 1999-09-08
BR9800426B1 BR9800426B1 (pt) 2010-05-18

Family

ID=8226392

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9800426-3A BR9800426B1 (pt) 1997-01-22 1998-01-21 processo para fabricação de derivados de benzofenona.

Country Status (17)

Country Link
US (1) US5877353A (pt)
EP (1) EP0855379B1 (pt)
JP (1) JP2888814B2 (pt)
KR (1) KR100268545B1 (pt)
CN (1) CN1092178C (pt)
AR (1) AR011542A1 (pt)
AT (1) ATE205177T1 (pt)
AU (1) AU733422B2 (pt)
BR (1) BR9800426B1 (pt)
CA (1) CA2227131C (pt)
DE (1) DE69801532T2 (pt)
DK (1) DK0855379T3 (pt)
ES (1) ES2162351T3 (pt)
ID (1) ID19540A (pt)
PT (1) PT855379E (pt)
TR (1) TR199800068A2 (pt)
ZA (1) ZA98347B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2401276A1 (en) * 2000-02-01 2001-08-09 Kyorin Pharmaceutical Co., Ltd. Alkali metal salt of thiazolidine-2,4-dione derivatives
KR20040026964A (ko) * 2002-09-27 2004-04-01 금호석유화학 주식회사 1,3-부타디엔과 아크릴산으로부터 시클로헥실 페닐 케톤의제조방법
EP1630600A3 (en) * 2004-07-29 2006-03-22 Rohm and Haas Electronic Materials, L.L.C. Hot melt composition and method involving forming a masking pattern
BR112020020351A2 (pt) * 2018-04-05 2021-01-12 Calasia Pharmaceuticals, Inc. Agentes farmacológicos para o tratamento de doenças oculares
CN108586224B (zh) * 2018-06-27 2021-05-25 天津大学 一种二苯甲酮纯化分离的方法
CN116963727A (zh) * 2020-11-13 2023-10-27 普莱克斯医药公司 用于治疗眼部病症的药剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
DE3643403A1 (de) * 1986-12-19 1988-06-30 Shell Agrar Gmbh & Co Kg Benzophenone und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
TR199800068A3 (tr) 1998-08-21
AU5210298A (en) 1998-07-30
KR19980070613A (ko) 1998-10-26
DE69801532D1 (de) 2001-10-11
CN1092178C (zh) 2002-10-09
TR199800068A2 (xx) 1998-08-21
KR100268545B1 (ko) 2000-10-16
PT855379E (pt) 2002-01-30
US5877353A (en) 1999-03-02
ID19540A (id) 1998-07-23
CN1188755A (zh) 1998-07-29
DE69801532T2 (de) 2002-05-23
JP2888814B2 (ja) 1999-05-10
ZA98347B (en) 1998-07-22
JPH10204021A (ja) 1998-08-04
AU733422B2 (en) 2001-05-17
CA2227131A1 (en) 1998-07-22
EP0855379A1 (en) 1998-07-29
AR011542A1 (es) 2000-08-30
DK0855379T3 (da) 2001-12-17
EP0855379B1 (en) 2001-09-05
BR9800426B1 (pt) 2010-05-18
MX9800608A (es) 1998-10-31
ES2162351T3 (es) 2001-12-16
ATE205177T1 (de) 2001-09-15
CA2227131C (en) 2008-10-07

Similar Documents

Publication Publication Date Title
BR0213380A (pt) Derivados propiÈnicos alfa-oxissubstituìdos por beta-fenila: processo para sua preparação e seu uso na preparação de compostos farmaceuticamente importantes
BR9802011A (pt) Processo para a produção de vanilina.
GT199900043A (es) Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxìlico.
BRPI0500480A (pt) processo para a sìntese de (1s)-4,5-dimetóxi- 1-(metilaminometil)-benzociclobutano e sais de adição deste, e aplicação na sìntese de ivabradina e sais de adição desta com um ácido farmaceuticamente aceitável
BR0015202A (pt) Processo para a purificação de uma solução contendo aminoácido por meio de eletrodiálise, e processo integrado para a produção de um aminoácido livre
BR9810657A (pt) &#34;processo de preparação de um per-hidroisoindol substituìdo&#34;
BR9800426A (pt) Processo para fabricação de derivados de benzofenona
BR9708233A (pt) Processo para sìntese de um composto e composto.
DK1341749T3 (da) Fremgangsmåde til fremstilling af gabapentin
BR0012631A (pt) Processo para a preparação de compostos de amina
BR9612690A (pt) Processo para a prepara-Æo de sais de cido 4,4&#39;-diaminoestilbeno-2,2&#39;-dissulfÄnico
BR9807988A (pt) Processo para a preparação de um composto, e, composto.
BR0304194A (pt) Processo para a sìntese industrial do metil diéster do ácido 5-amino-3-carboximetil-4-ciano-2-tiofeno carboxìlico, e aplicação para a sìntese dos sais bivalentes do ácido ranélico e dos hidratos do mesmo
BR0210664A (pt) Processo de sìntese técnico para produção de tropenol
BR9910085A (pt) Processo para a cristalização de um antibiótico de beta-lactama
IT1301993B1 (it) Processo per la preparazione di zofenopril sale di calcio.
BR0209842A (pt) Processo para a preparação de imipenem
BR0210512A (pt) Processo de decomposição papa o ácido (r)-(-)-2-hidroxi-2-(2-clorofenil) acético
DK0636607T3 (da) Fremgangsmåde til krystallisation af methionin
PT947499E (pt) Processo de preparacao da sertralina racemica
BR0000184A (pt) Processo para a preparação de compostos heterocìclicos
BR0209843A (pt) Processo para a preparação de cilastatina sódica amorfa
BR9915684A (pt) Semicloridrato de ácido 8-cian-1-ciclopropil-7-(1s,6s-2,8-diazabiciclo-[4.3.0]-non an-8-il)-6-flúor-1,4-dihidro-4-oxo-3-quinolinocarboxìli co
ES2115809T3 (es) Recuperacion de sales de acidos organicos de corrientes de proceso impuras mediante adicion de bases.
BR0112876A (pt) Processo para preparação de discodermolida e seus análogos

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: VALEANT GLOBAL ACQUISITION COMPANY PTE. LTD. (SG)

Free format text: TRANSFERIDO DE: F. HOFFMANN-LA ROCHE AG

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/05/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 22A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2550 DE 19-11-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.