BR9307736A - Processo para preparação de formulações farmacêuticas com ingrediente ativo liberado sob controle para administração oral, tópica ou parenteral - Google Patents
Processo para preparação de formulações farmacêuticas com ingrediente ativo liberado sob controle para administração oral, tópica ou parenteralInfo
- Publication number
- BR9307736A BR9307736A BR9307736-0A BR9307736A BR9307736A BR 9307736 A BR9307736 A BR 9307736A BR 9307736 A BR9307736 A BR 9307736A BR 9307736 A BR9307736 A BR 9307736A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- active ingredient
- topical
- oral
- under control
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção para: <B>"PROCESSO PARA PREPARAçãO DE FORMULAçõES FARMACêUTICAS COM INGREDIENTE ATIVO LIBERADO SOB CONTROLE PARA ADMINISTRAçãO ORAL, TóPICA OU PARENTERAL"<D>. Processo aperfeiçoado para preparação de formulações farmacêuticas com liberação sob controle compreende a exposição da mistura compreendendo um ou mais excipientes e um ou mais ingredientes ativos compatíveis um com o outro e com os ditos excipientes a ações mecânicas ou eletromecânicas, por um período de tempo estabelecido e dentro de uma ampla faixa de freq³ências, para fornecer comprimidos, matrizes ou películas mono ou de multicamada. Ditas formulações podem ser opcionalmente moídas para fornecer um granulado ou pó. Dependendo do excipiente empregado, pode ser obtida uma liberação retardada ou rápida, porém sempre controlada ou ingrediente ativo.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT92BO455 IT1260242B (it) | 1992-12-23 | 1992-12-23 | Procedimento per preparare forme farmaceutiche a rilascio controllato ritardato del principio attivo e le forme farmaceutiche cosi' ottenute. |
ITBO930294A IT1263445B (it) | 1993-06-24 | 1993-06-24 | Procedimento per preparare forme farmaceutiche a rilascio controllato/ritardato del principio attivo e le forme farmaceutiche cosi' ottenute |
IT93BO000460A IT1268454B1 (it) | 1993-11-12 | 1993-11-12 | Procedimento per preparare forme farmaceutiche a rilascio controllato del principio attivo e le forme farmaceutiche cosi' ottenute. |
PCT/IT1993/000136 WO1994014421A2 (en) | 1992-12-23 | 1993-12-23 | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9307736A true BR9307736A (pt) | 1999-08-31 |
Family
ID=27273889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9307736-0A BR9307736A (pt) | 1992-12-23 | 1993-12-23 | Processo para preparação de formulações farmacêuticas com ingrediente ativo liberado sob controle para administração oral, tópica ou parenteral |
Country Status (14)
Country | Link |
---|---|
US (1) | US5662935A (pt) |
EP (1) | EP0675710B1 (pt) |
JP (1) | JP3459421B2 (pt) |
KR (1) | KR100297541B1 (pt) |
AT (1) | ATE183641T1 (pt) |
AU (1) | AU683044B2 (pt) |
BR (1) | BR9307736A (pt) |
CA (1) | CA2151396C (pt) |
DE (1) | DE69326163T2 (pt) |
DK (1) | DK0675710T3 (pt) |
ES (1) | ES2138070T3 (pt) |
GR (1) | GR3031936T3 (pt) |
RU (1) | RU2128499C1 (pt) |
WO (1) | WO1994014421A2 (pt) |
Families Citing this family (53)
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US5821237A (en) * | 1995-06-07 | 1998-10-13 | The Procter & Gamble Company | Compositions for visually improving skin |
TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
FR2757397B1 (fr) * | 1996-12-23 | 1999-03-05 | Mazal Pharma | Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree |
US6046177A (en) * | 1997-05-05 | 2000-04-04 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations |
IT1292588B1 (it) * | 1997-05-28 | 1999-02-08 | Saitec Srl | Procedimento per preparare forme alimentari ad elevata resa di sapore e le forme alimentari cosi' ottenute. |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
FR2806307B1 (fr) * | 2000-03-20 | 2002-11-15 | Mane Fils V | Preparation parfumee solide sous forme de microbilles et utilisation de ladite preparation |
US7201891B1 (en) * | 2000-05-19 | 2007-04-10 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical preparation for the diagnosis of helicobacter pylori infection |
SG98393A1 (en) | 2000-05-19 | 2003-09-19 | Inst Materials Research & Eng | Injectable drug delivery systems with cyclodextrin-polymer based hydrogels |
US20030099703A1 (en) * | 2000-08-11 | 2003-05-29 | Shigeru Aoki | Drug-containing solid dispersion having improved solubility |
BR0102252B1 (pt) * | 2001-04-10 | 2013-10-22 | Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso | |
ITBO20020094A1 (it) | 2002-02-22 | 2003-08-22 | Tecnea Engineering S R L | Procedimento per la realizzazione di composizioni ed apparecchiatura realizzante tale procedimento |
JP2005298338A (ja) * | 2002-02-27 | 2005-10-27 | Eisai Co Ltd | 速崩壊性圧縮成形製剤 |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10315640A1 (de) * | 2003-04-04 | 2004-10-14 | Ignatov, Konstantin | Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
WO2005049306A1 (en) * | 2003-11-18 | 2005-06-02 | Eurand Pharmaceuticals Limited | Ultrasound-assisted compaction process with a compaction device made of coupled plastic-metal materials |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005024171A1 (de) * | 2005-03-22 | 2006-09-28 | Grünenthal GmbH | Verfahren und Vorrichtung zur Ultraschallverpressung einer Tablette oder einer multipartikulären Arzneiform |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
WO2008109723A1 (en) * | 2007-03-08 | 2008-09-12 | Smithkline Beecham Corporation | Pharmaceutical analysis apparatus and method |
RU2351352C2 (ru) * | 2007-04-09 | 2009-04-10 | Закрытое акционерное общество "Санкт-Петербургский институт фармации" | Твердая нанокомпозиция для доставки биологически активных веществ |
US8383152B2 (en) | 2008-01-25 | 2013-02-26 | Gruenenthal Gmbh | Pharmaceutical dosage form |
SI2273983T1 (sl) | 2008-05-09 | 2016-11-30 | Gruenenthal Gmbh | Postopek za pripravo intermediatne praškaste formulacije in končne trdne odmerne oblike z uporabo stopnje strjevanja z razprševanjem |
TWI473610B (zh) * | 2008-10-28 | 2015-02-21 | Twi Biotechnology Inc | 包含雙醋瑞因(diacerein)之醫藥組合物 |
TW201105316A (en) | 2009-07-22 | 2011-02-16 | Gruenenthal Gmbh | Hot-melt extruded pharmaceutical dosage form |
AU2010275755B2 (en) | 2009-07-22 | 2014-04-24 | Grünenthal GmbH | Oxidation-stabilized tamper-resistant dosage form |
MX2013002377A (es) | 2010-09-02 | 2013-04-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a manipulacion que comprende una sal inorganica. |
CN103179954A (zh) | 2010-09-02 | 2013-06-26 | 格吕伦塔尔有限公司 | 包含阴离子聚合物的抗破碎剂型 |
US10201502B2 (en) | 2011-07-29 | 2019-02-12 | Gruenenthal Gmbh | Tamper-resistant tablet providing immediate drug release |
RS56527B1 (sr) | 2011-07-29 | 2018-02-28 | Gruenenthal Gmbh | Tableta za trenutno oslobađanje leka rezistentna na zloupotrebu |
MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
EA201401139A1 (ru) | 2012-04-18 | 2015-03-31 | Грюненталь Гмбх | Устойчивая к разрушению и к сбросу дозы фармацевтическая лекарственная форма |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
BR112015026549A2 (pt) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | forma de dosagem à prova de violação contendo uma ou mais partículas |
CA2913209A1 (en) | 2013-05-29 | 2014-12-04 | Grunenthal Gmbh | Tamper resistant dosage form with bimodal release profile |
CA2917136C (en) | 2013-07-12 | 2022-05-31 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
CN105555847B (zh) | 2013-09-19 | 2018-08-10 | 微仙美国有限公司 | 聚合物膜 |
CN110279885B (zh) | 2013-09-19 | 2022-07-26 | 泰尔茂株式会社 | 聚合物颗粒 |
CN105916495B (zh) | 2013-11-08 | 2019-11-12 | 泰尔茂株式会社 | 聚合物颗粒 |
WO2015078891A1 (en) | 2013-11-26 | 2015-06-04 | Farmaceutici Formenti S.P.A. | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
WO2015173195A1 (en) | 2014-05-12 | 2015-11-19 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
MX2016015417A (es) | 2014-05-26 | 2017-02-22 | Gruenenthal Gmbh | Multiparticulas protegidas contra vertido de dosis etanolico. |
WO2016154592A1 (en) | 2015-03-26 | 2016-09-29 | Microvention, Inc. | Embiolic particles |
EP3285745A1 (en) | 2015-04-24 | 2018-02-28 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
AU2017336786B2 (en) | 2016-09-28 | 2020-04-09 | Terumo Corporation | Polymer particles |
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US2828206A (en) * | 1954-02-24 | 1958-03-25 | Roseuberg Adolf | Stabilized fat-soluble vitamins and methods of making same |
US3078216A (en) * | 1961-04-11 | 1963-02-19 | American Cyanamid Co | Prolonged release oral pharmaceutical preparations |
US3137630A (en) * | 1961-06-09 | 1964-06-16 | Eastman Kodak Co | Process for preparing a dry, finely divided, gelatin particle product |
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BR6457270D0 (pt) * | 1963-03-04 | 1973-09-20 | Merck & Co Inc | Processo de preparacao de uma composicao farmaceutica provendo uma liberacao prolongada de uma droga no aparelho gastro intestinal |
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JP2958103B2 (ja) * | 1989-12-12 | 1999-10-06 | エーザイ株式会社 | プラズマ照射固形製剤 |
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FR2664851B1 (fr) * | 1990-07-20 | 1992-10-16 | Oreal | Procede de compactage d'un melange pulverulent permettant d'obtenir un produit compact absorbant ou partiellement delitable et produit obtenu par ce procede. |
DE4031881C2 (de) * | 1990-10-08 | 1994-02-24 | Sanol Arznei Schwarz Gmbh | Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung |
-
1993
- 1993-12-23 JP JP51499394A patent/JP3459421B2/ja not_active Expired - Fee Related
- 1993-12-23 RU RU95113481/14A patent/RU2128499C1/ru not_active IP Right Cessation
- 1993-12-23 DK DK94906994T patent/DK0675710T3/da active
- 1993-12-23 DE DE69326163T patent/DE69326163T2/de not_active Expired - Lifetime
- 1993-12-23 AU AU60434/94A patent/AU683044B2/en not_active Ceased
- 1993-12-23 EP EP94906994A patent/EP0675710B1/en not_active Expired - Lifetime
- 1993-12-23 WO PCT/IT1993/000136 patent/WO1994014421A2/en active IP Right Grant
- 1993-12-23 AT AT94906994T patent/ATE183641T1/de not_active IP Right Cessation
- 1993-12-23 ES ES94906994T patent/ES2138070T3/es not_active Expired - Lifetime
- 1993-12-23 BR BR9307736-0A patent/BR9307736A/pt unknown
- 1993-12-23 CA CA002151396A patent/CA2151396C/en not_active Expired - Fee Related
- 1993-12-23 US US08/464,708 patent/US5662935A/en not_active Expired - Lifetime
- 1993-12-23 KR KR1019950702632A patent/KR100297541B1/ko not_active IP Right Cessation
-
1999
- 1999-11-24 GR GR990403029T patent/GR3031936T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0675710T3 (da) | 2000-03-27 |
CA2151396A1 (en) | 1994-07-07 |
DE69326163T2 (de) | 2000-05-04 |
US5662935A (en) | 1997-09-02 |
ES2138070T3 (es) | 2000-01-01 |
EP0675710B1 (en) | 1999-08-25 |
DE69326163D1 (de) | 1999-09-30 |
GR3031936T3 (en) | 2000-03-31 |
ATE183641T1 (de) | 1999-09-15 |
AU683044B2 (en) | 1997-10-30 |
EP0675710A1 (en) | 1995-10-11 |
KR100297541B1 (ko) | 2001-11-26 |
WO1994014421A3 (en) | 1994-08-18 |
CA2151396C (en) | 2006-08-22 |
JPH08504807A (ja) | 1996-05-28 |
AU6043494A (en) | 1994-07-19 |
WO1994014421A2 (en) | 1994-07-07 |
RU2128499C1 (ru) | 1999-04-10 |
JP3459421B2 (ja) | 2003-10-20 |
KR960700043A (ko) | 1996-01-19 |
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Legal Events
Date | Code | Title | Description |
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EG | Technical examination (opinion): publication of technical examination (opinion) | ||
CKFC | Appeal: appeal against refusal |