BR112019024661A2 - Isolamento de células de origem epitelial circulantes no sangue periférico - Google Patents

Isolamento de células de origem epitelial circulantes no sangue periférico Download PDF

Info

Publication number
BR112019024661A2
BR112019024661A2 BR112019024661-4A BR112019024661A BR112019024661A2 BR 112019024661 A2 BR112019024661 A2 BR 112019024661A2 BR 112019024661 A BR112019024661 A BR 112019024661A BR 112019024661 A2 BR112019024661 A2 BR 112019024661A2
Authority
BR
Brazil
Prior art keywords
epithelial cells
peripheral blood
isolation
circulating epithelial
circulating
Prior art date
Application number
BR112019024661-4A
Other languages
English (en)
Inventor
José Romero Palacios Pedro
José Díaz Mochón Juan
Antonio Lorente Acosta José
De Miguel Pérez Diego
José Serrano Fernández María
Alcázar Navarrete Bernardino
Original Assignee
Universidad De Granada
Servicio Andaluz De Salud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad De Granada, Servicio Andaluz De Salud filed Critical Universidad De Granada
Publication of BR112019024661A2 publication Critical patent/BR112019024661A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
    • A47K5/00—Holders or dispensers for soap, toothpaste, or the like
    • A47K5/06—Dispensers for soap
    • A47K5/12—Dispensers for soap for liquid or pasty soap
    • A47K5/1217—Electrical control means for the dispensing mechanism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

a presente invenção refere-se a um método de identificação de células epiteliais circulantes no sangue periférico que permite distinguir entre indivíduos que padecem de uma enfermidade que se apresenta com destruição de células epiteliais ou não, assim como o kit ou dispositivo para a realização dos métodos da invenção.
BR112019024661-4A 2017-05-24 2018-05-24 Isolamento de células de origem epitelial circulantes no sangue periférico BR112019024661A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP201730724 2017-05-24
ES201730724 2017-05-24
PCT/ES2018/070377 WO2018215686A1 (es) 2017-05-24 2018-05-24 Aislamiento de células de origen epitelial circulantes en sangre periférica

Publications (1)

Publication Number Publication Date
BR112019024661A2 true BR112019024661A2 (pt) 2020-06-16

Family

ID=62386631

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019024661-4A BR112019024661A2 (pt) 2017-05-24 2018-05-24 Isolamento de células de origem epitelial circulantes no sangue periférico

Country Status (5)

Country Link
US (2) US20200278347A1 (pt)
EP (1) EP3647784A4 (pt)
CN (1) CN111213058A (pt)
BR (1) BR112019024661A2 (pt)
WO (1) WO2018215686A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9725710B2 (en) 2014-01-08 2017-08-08 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
CN116699137B (zh) * 2023-06-26 2024-04-05 深圳市瑞格生物科技有限公司 一种评估患有肿瘤或特定肿瘤风险的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200523370A (en) * 2004-01-06 2005-07-16 Feng-Jou Shie Method to determine if an individual has suffered from pulmonary disease or is in danger of developing pulmonary disease, and method to sieve out compound used in preventing or curing pulmonary disease
WO2007149447A2 (en) * 2006-06-16 2007-12-27 The Board Of Trustees Of The Leland Stanford Junior University Lung progenitor cells, assays, and uses thereof
US20080057505A1 (en) * 2006-07-14 2008-03-06 Ping Lin Methods and compositions for detecting rare cells from a biological sample
EP2678448A4 (en) * 2011-02-22 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L CIRCULATING BIOMARKERS
US20120237931A1 (en) * 2011-03-14 2012-09-20 Katz Ruth L Identification and monitoring of circulating cancer stem cells
ES2437240B1 (es) * 2012-06-05 2014-10-16 Servicio Andaluz De Salud Método de obtención de datos útiles para el diagnóstico, pronóstico y clasificación de los pacientes con enfermedad pulmonar obstructiva crónica (EPOC) y/o cáncer de pulmón
CN105063168B (zh) * 2015-07-17 2019-01-18 上海交通大学 检测血液中游离上皮细胞器官来源的装置

Also Published As

Publication number Publication date
US20220050098A1 (en) 2022-02-17
US20200278347A1 (en) 2020-09-03
EP3647784A1 (en) 2020-05-06
EP3647784A4 (en) 2021-06-23
WO2018215686A9 (es) 2019-06-06
WO2018215686A1 (es) 2018-11-29
CN111213058A (zh) 2020-05-29

Similar Documents

Publication Publication Date Title
BR112019024661A2 (pt) Isolamento de células de origem epitelial circulantes no sangue periférico
EA201792642A1 (ru) Способы диагностики для т-клеточной терапии
EA201692477A1 (ru) Композиции и способы применения для лечения метаболических расстройств
BR112018075288A2 (pt) métodos para diagnóstico de infecções bacterianas e virais
PE20210650A1 (es) Terapia basada en anticuerpos de amiloidosis por transtiretina (ttr) y anticuerpos derivados de humanos de la misma
WO2016109782A3 (en) Methods and compositions for detecting colorectal neoplasias
BR112017000464A2 (pt) células gama delta t e uso das mesmas
BR112017008453A2 (pt) detecção automática de incompatibilidade de esquema
MX2020010947A (es) Metodos de tratamiento de enfermedad de alzheimer.
BR112017026709A2 (pt) tratamento e diagnóstico de câncer
BR112016014876A2 (pt) composto que modula a quantidade ou a atividade de gibspla2, composição farmacêutica, imunógeno que induz uma resposta imune anti-gibspla2, composição de vacina, método para o diagnóstico da imunodeficiência humana associada com a alteração de células t, e, método para a produção de gibspla2
CL2017001301A1 (es) Composiciones oftálmicas estabilizadas de omega 3
EA201790504A1 (ru) Монослой мононуклеарных клеток периферической крови или клеток костного мозга и его применение
FR3021970B1 (fr) Anticorps dirige contre la galectine 9 et inhibiteur de l'activite suppressive des lymphocytes t regulateurs
CL2016001076A1 (es) (aza) piridopirazolopirimidinonas e indazolopirimidinonas como inhibidores de fibrinolosis.
CL2014002975A1 (es) Método in vitro para el diagnostico y vigilancia del cáncer, que comprende determinar la razón entre las células treg y otro grupo de células t, seleccionadas de th17, th1 y/o th2.
WO2017066712A3 (en) Modulators of telomere disease
ES2811835T3 (es) Procedimiento para determinar el riesgo de toxicidad por 5-fluorouracilo
WO2015073896A3 (en) Biomarkers for psma targeted therapy for prostate cancer
BR112018003780A2 (pt) composições que compreendem um composto de urolitina
PT110171A (pt) Método de treino da capacidade cognitiva com base emocional
MX2022010954A (es) Dispositivo para la deteccion de proteinas mal plegadas y metodos de uso del mismo.
CY1122474T1 (el) Μεθοδος διαγνωσης νευραλγιας του τριδυμου
CL2020001936A1 (es) Métodos para el tratamiento de la atrofía muscular espinal.
EA201592265A1 (ru) Маркер для ассоциированных с кислой сфингомиелиназой нарушений и его применения

Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2724 DE 21-03-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.