BR112018070187A8 - receptores quiméricos para flt3 e seus métodos de uso - Google Patents

receptores quiméricos para flt3 e seus métodos de uso Download PDF

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Publication number
BR112018070187A8
BR112018070187A8 BR112018070187A BR112018070187A BR112018070187A8 BR 112018070187 A8 BR112018070187 A8 BR 112018070187A8 BR 112018070187 A BR112018070187 A BR 112018070187A BR 112018070187 A BR112018070187 A BR 112018070187A BR 112018070187 A8 BR112018070187 A8 BR 112018070187A8
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Brazil
Prior art keywords
flt3
methods
chimeric receptors
antigen binding
immune cells
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BR112018070187A
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English (en)
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BR112018070187A2 (pt
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Bakker Alice
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Amgen Inc
Kite Pharma Inc
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Publication of BR112018070187A2 publication Critical patent/BR112018070187A2/pt
Publication of BR112018070187A8 publication Critical patent/BR112018070187A8/pt

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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • C12Y207/10—Protein-tyrosine kinases (2.7.10)
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
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Abstract

as moléculas de ligação ao antígeno, receptores quiméricos e células imunológicas manipuladas a flt3 são divulgadas de acordo com a invenção. a invenção se refere ainda a vetores, composições e modos de tratamento e/ou detecção utilizando as moléculas de ligação ao antígeno flt3 e células imunológicas manipuladas.
BR112018070187A 2016-04-01 2017-03-31 receptores quiméricos para flt3 e seus métodos de uso BR112018070187A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317219P 2016-04-01 2016-04-01
PCT/US2017/025613 WO2017173410A1 (en) 2016-04-01 2017-03-31 Chimeric receptors to flt3 and methods of use thereof

Publications (2)

Publication Number Publication Date
BR112018070187A2 BR112018070187A2 (pt) 2019-01-29
BR112018070187A8 true BR112018070187A8 (pt) 2019-11-05

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BR112018070187A BR112018070187A8 (pt) 2016-04-01 2017-03-31 receptores quiméricos para flt3 e seus métodos de uso

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US (2) US20190183931A1 (pt)
EP (1) EP3436479A1 (pt)
JP (2) JP2019516352A (pt)
KR (2) KR102389096B1 (pt)
CN (1) CN109641956A (pt)
AR (2) AR109626A1 (pt)
AU (2) AU2017240801A1 (pt)
BR (1) BR112018070187A8 (pt)
CA (1) CA3019655A1 (pt)
CL (1) CL2018002792A1 (pt)
CO (1) CO2018011804A2 (pt)
CR (1) CR20180518A (pt)
EA (1) EA201892193A1 (pt)
IL (2) IL296966A (pt)
MA (1) MA44507A (pt)
MX (1) MX2023013729A (pt)
MY (1) MY201207A (pt)
NZ (1) NZ746925A (pt)
PE (2) PE20190201A1 (pt)
PH (1) PH12018502118A1 (pt)
SA (1) SA518400154B1 (pt)
SG (2) SG11201808622SA (pt)
TN (1) TN2018000337A1 (pt)
TW (2) TWI776807B (pt)
UA (1) UA128326C2 (pt)
WO (1) WO2017173410A1 (pt)

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