BR112015021164A8 - composto de xantina substituída e seu sal - Google Patents

composto de xantina substituída e seu sal Download PDF

Info

Publication number
BR112015021164A8
BR112015021164A8 BR112015021164A BR112015021164A BR112015021164A8 BR 112015021164 A8 BR112015021164 A8 BR 112015021164A8 BR 112015021164 A BR112015021164 A BR 112015021164A BR 112015021164 A BR112015021164 A BR 112015021164A BR 112015021164 A8 BR112015021164 A8 BR 112015021164A8
Authority
BR
Brazil
Prior art keywords
salt
compound
substituted xanthine
methods
trpc5
Prior art date
Application number
BR112015021164A
Other languages
English (en)
Other versions
BR112015021164B1 (pt
BR112015021164A2 (pt
Inventor
Chenard Bertrand
Gallaschun Randall
Original Assignee
Hydra Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50680155&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015021164(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hydra Biosciences Inc filed Critical Hydra Biosciences Inc
Publication of BR112015021164A2 publication Critical patent/BR112015021164A2/pt
Publication of BR112015021164A8 publication Critical patent/BR112015021164A8/pt
Publication of BR112015021164B1 publication Critical patent/BR112015021164B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings

Abstract

resumo patente de invenção: "xantinas substituídas e métodos de uso das mesmas". a presente invenção refere-se a compostos, composições e métodos para a inibição do canal de íon de trpc5 e distúrbios relacionados com trpc5.
BR112015021164-0A 2013-03-15 2014-03-14 Composto de xantina substituída e seu sal BR112015021164B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361789724P 2013-03-15 2013-03-15
US61/789,724 2013-03-15
PCT/US2014/027920 WO2014143799A2 (en) 2013-03-15 2014-03-14 Substituted xanthines and methods of use thereof

Publications (3)

Publication Number Publication Date
BR112015021164A2 BR112015021164A2 (pt) 2017-07-18
BR112015021164A8 true BR112015021164A8 (pt) 2019-12-03
BR112015021164B1 BR112015021164B1 (pt) 2023-05-30

Family

ID=

Also Published As

Publication number Publication date
HK1217329A1 (zh) 2017-01-06
SG11201506479TA (en) 2015-09-29
HUE033528T4 (en) 2018-05-02
HRP20170840T1 (hr) 2017-09-08
PH12015502141A1 (en) 2016-01-25
US11208409B2 (en) 2021-12-28
TW201533044A (zh) 2015-09-01
IL240216B (en) 2018-11-29
KR102227629B1 (ko) 2021-03-16
AU2014228206C1 (en) 2018-10-25
US20180244674A1 (en) 2018-08-30
CN107082782A (zh) 2017-08-22
CY1119042T1 (el) 2018-01-10
UA117470C2 (uk) 2018-08-10
US20190322667A1 (en) 2019-10-24
DK2970303T6 (en) 2018-10-08
UY35488A (es) 2014-10-31
MX2015011617A (es) 2016-04-25
KR20150133233A (ko) 2015-11-27
RS56066B1 (sr) 2017-10-31
US20140275071A1 (en) 2014-09-18
EP2970303B9 (en) 2017-09-20
US11958854B2 (en) 2024-04-16
ES2636835T7 (es) 2018-11-20
MX370372B (es) 2019-12-11
EP2970303A2 (en) 2016-01-20
CN105143229B (zh) 2017-06-30
EP2970303B1 (en) 2017-05-10
WO2014143799A4 (en) 2015-02-12
DK2970303T5 (en) 2018-01-02
WO2014143799A3 (en) 2014-11-06
MY189912A (en) 2022-03-21
TWI609867B (zh) 2018-01-01
US20170305910A1 (en) 2017-10-26
PL2970303T3 (pl) 2017-08-31
WO2014143799A2 (en) 2014-09-18
SI2970303T1 (sl) 2017-08-31
LT2970303T (lt) 2017-07-25
EP2970303B3 (en) 2018-08-01
PL2970303T6 (pl) 2018-12-31
JP2016513717A (ja) 2016-05-16
NZ711718A (en) 2020-05-29
CN107082782B (zh) 2020-03-20
US9969736B2 (en) 2018-05-15
BR112015021164A2 (pt) 2017-07-18
CN105143229A (zh) 2015-12-09
PT2970303T (pt) 2017-06-23
CL2015002738A1 (es) 2016-06-10
US10399982B2 (en) 2019-09-03
PE20151779A1 (es) 2015-11-20
EA028815B1 (ru) 2018-01-31
US20230040259A1 (en) 2023-02-09
US20160237089A1 (en) 2016-08-18
ES2636835T3 (es) 2017-10-09
JP6360149B2 (ja) 2018-07-18
CA2899646C (en) 2021-08-31
PH12015502141B1 (en) 2016-01-25
RS56066B2 (sr) 2018-09-28
DK2970303T3 (en) 2017-06-26
ZA201505414B (en) 2016-03-30
AU2014228206A1 (en) 2015-09-24
IL240216A0 (en) 2015-09-24
HRP20170840T4 (hr) 2018-11-16
WO2014143799A9 (en) 2014-12-24
US9359359B2 (en) 2016-06-07
AU2014228206B2 (en) 2018-05-10
EA201591615A1 (ru) 2016-05-31
CA2899646A1 (en) 2014-09-18
HUE033528T2 (hu) 2017-12-28

Similar Documents

Publication Publication Date Title
CY1119042T1 (el) Υποκατεστημενες ξανθινες και μεθοδοι χρησης αυτων
PH12019501321A1 (en) Methods of treating or preventing cholesterol related disorders
MX2018000396A (es) Compuestos aza sustituidos como inhibidores de cinasa 4 asociada al receptor de interleucina 1 (irak-4).
PH12016500105A1 (en) Sulfonamides as modulators of sodium channels
BR112015021521A2 (pt) anticorpos anti-crth2 e métodos para seu uso
BR112016008541A2 (pt) composições úteis para tratar distúrbios relacionados a kit
EA201690752A1 (ru) Ингибиторы g12c kras
BR112015022191A2 (pt) compostos heteroarila, seu uso e composição que os compreende
BR112012023660B8 (pt) usos de uma quantidade terapeuticamente eficaz de um composto, ou de um sal, solvato, hidrato ou pró-fármaco farmaceuticamente aceitável do mesmo para o tratamento de câncer
EA201790337A1 (ru) Кристаллические формы ингибиторов глутаминазы
WO2014152287A3 (en) Substituted xanthines and methods of use thereof
EA201690844A1 (ru) Ингибиторы gsk-3
BR112015009649A2 (pt) composto de triazolo
UA117032C2 (uk) Селективний інгібітор фосфатидилінозитол-3-кінази-гамма
ECSP16008797A (es) Derivados de heterobicicloaril como inhibidores rorc2 y métodos de uso de los mismos
BR112017006002A2 (pt) compostos de imidazopiridazina e seu uso
BR112018003331A2 (pt) sondas para imagear proteína huntingtina
GEP20196984B (en) Pyridazine derivatives for use in the prevention or treatment of an ataxic disorder
BR112017021583A2 (pt) métodos para o tratamento de transtornos inflamatórios
DOP2019000021A (es) Derivado de triazolopirazinona útil como un inhibidor de pde1 humana
BR112017016396A2 (pt) composto, composição farmacêutica, uso de um composto, e, método.
EA201600002A1 (ru) Производные пролекарства замещенных триазолопиридинов
BR112017024126B8 (pt) Composições farmacêuticas, composto a micronizado e/ou pelo menos um sal farmaceuticamente aceitável micronizado do composto a e uso dos mesmos
BR112016008704A8 (pt) derivados de indol-urea glucopiranosil-substituídos, composições farmacêuticas, e seus usos
BR112015023463A2 (pt) uso de sedoeptulose para prevenção ou tratamento de inflamação

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25A Requested transfer of rights approved

Owner name: HYDRA BIOSCIENCES, LLC (US)

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/03/2014, OBSERVADAS AS CONDICOES LEGAIS