BR112014016005A8 - alterações genéticas para produção de butanol - Google Patents

alterações genéticas para produção de butanol

Info

Publication number
BR112014016005A8
BR112014016005A8 BR112014016005A BR112014016005A BR112014016005A8 BR 112014016005 A8 BR112014016005 A8 BR 112014016005A8 BR 112014016005 A BR112014016005 A BR 112014016005A BR 112014016005 A BR112014016005 A BR 112014016005A BR 112014016005 A8 BR112014016005 A8 BR 112014016005A8
Authority
BR
Brazil
Prior art keywords
genetic alterations
butanol production
butanol
production
genetic
Prior art date
Application number
BR112014016005A
Other languages
English (en)
Other versions
BR112014016005A2 (pt
Inventor
Leo Kruckeberg Arthur
James Paul Brian
Frederich Tuminello Joseph
Dauner Michael
A Larossa Robert
Suh Wonchul
Original Assignee
Butamax Advanced Biofuels Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Butamax Advanced Biofuels Llc filed Critical Butamax Advanced Biofuels Llc
Publication of BR112014016005A2 publication Critical patent/BR112014016005A2/pt
Publication of BR112014016005A8 publication Critical patent/BR112014016005A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16Butanols
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001Alcohol dehydrogenase (1.1.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01008Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01043Phosphogluconate 2-dehydrogenase (1.1.1.43)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01047Glucose 1-dehydrogenase (1.1.1.47)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01086Ketol-acid reductoisomerase (1.1.1.86)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y202/00Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01Transketolases and transaldolases (2.2.1)
    • C12Y202/01006Acetolactate synthase (2.2.1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/01Carboxylic ester hydrolases (3.1.1)
    • C12Y301/010316-Phosphogluconolactonase (3.1.1.31)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03009Glucose-6-phosphatase (3.1.3.9)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/02Aldehyde-lyases (4.1.2)
    • C12Y401/02009Phosphoketolase (4.1.2.9)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112014016005A 2011-12-30 2012-12-28 alterações genéticas para produção de butanol BR112014016005A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161581888P 2011-12-30 2011-12-30
PCT/US2012/072186 WO2013102147A2 (en) 2011-12-30 2012-12-28 Genetic switches for butanol production

Publications (2)

Publication Number Publication Date
BR112014016005A2 BR112014016005A2 (pt) 2017-06-13
BR112014016005A8 true BR112014016005A8 (pt) 2017-07-04

Family

ID=47559747

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014016005A BR112014016005A8 (pt) 2011-12-30 2012-12-28 alterações genéticas para produção de butanol

Country Status (10)

Country Link
US (1) US9181566B2 (pt)
EP (1) EP2798071A2 (pt)
JP (1) JP2015503351A (pt)
KR (1) KR20140113997A (pt)
CN (1) CN104284980A (pt)
AU (1) AU2012362144A1 (pt)
BR (1) BR112014016005A8 (pt)
CA (1) CA2862450A1 (pt)
MX (1) MX2014008073A (pt)
WO (1) WO2013102147A2 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
EP2337856A1 (en) 2008-09-29 2011-06-29 Butamax Advanced Biofuels Llc INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
EP2519628A2 (en) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
AU2011218090B2 (en) 2010-02-17 2016-06-23 Butamax(Tm) Advanced Biofuels Llc Improving activity of Fe-S cluster requiring proteins
EP3269806B1 (en) 2010-09-07 2020-05-27 Butamax (TM) Advanced Biofuels LLC Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
JP6093764B2 (ja) 2011-07-28 2017-03-08 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法
EP2798072A2 (en) 2011-12-30 2014-11-05 Butamax Advanced Biofuels LLC Fermentative production of alcohols
WO2013142338A1 (en) 2012-03-23 2013-09-26 Butamax(Tm) Advanced Biofuels Llc Acetate supplemention of medium for butanologens
CA2873109A1 (en) 2012-05-11 2013-11-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
US9593349B2 (en) 2012-08-22 2017-03-14 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US9840724B2 (en) 2012-09-21 2017-12-12 Butamax Advanced Biofuels Llc Production of renewable hydrocarbon compositions
WO2014052670A1 (en) 2012-09-26 2014-04-03 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
WO2014106107A2 (en) * 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
HUE045200T2 (hu) 2013-03-14 2019-12-30 Du Pont Glicerin-3-foszfát dehidrogenáz butanol elõállítására
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
WO2015002913A1 (en) 2013-07-03 2015-01-08 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
WO2015002919A2 (en) * 2013-07-03 2015-01-08 Butamax Advanced Biofuels Llc Regulation of production pathways in host cells
WO2015009601A1 (en) * 2013-07-16 2015-01-22 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving cell wall proteins
JP2015128397A (ja) * 2014-01-08 2015-07-16 国立大学法人広島大学 亜リン酸デヒドロゲナーゼ遺伝子、および、当該遺伝子を用いた出芽酵母の選択的培養方法
CA2957920A1 (en) * 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same
PT3237601T (pt) * 2014-12-23 2020-08-20 Carlsberg Breweries As Levedura para preparação de bebidas alcoólicas
WO2016205753A1 (en) * 2015-06-17 2016-12-22 The Translational Genomics Research Institute Systems and methods for obtaining biological molecules from a sample
WO2017216136A1 (en) * 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
WO2018132512A1 (en) * 2017-01-10 2018-07-19 Massachusetts Institute Of Technology Constructs and cells for enhanced protein expression
MX2019009032A (es) * 2017-01-30 2019-09-10 Intrexon Corp Metodos y microorganismos para elaborar 2,3-butandiol y derivados de los mismos a partir de carbonos c1.
WO2018200894A1 (en) * 2017-04-28 2018-11-01 Intrexon Corporation Methods and microorganisms for the fermentation of methane to multi-carbon compounds
CN107177623B (zh) * 2017-05-24 2020-01-07 梁恒宇 一种高产甘油低产乙酸的葡萄酒用酿酒酵母菌株及构建方法
CN108226367A (zh) * 2017-12-29 2018-06-29 青岛啤酒股份有限公司 一种啤酒中丙三醇的检测方法
HUE062297T2 (hu) * 2019-01-29 2023-10-28 Clariant Produkte Deutschland Gmbh Kiméra promóter anyagcsere módosítási alkalmazásra
CN110551644A (zh) * 2019-07-19 2019-12-10 天津科技大学 通过调控细胞壁组成蛋白构建的低产高级醇酿酒酵母菌株
CN114555778A (zh) 2019-08-29 2022-05-27 丹尼斯科美国公司 在酵母中表达β-葡糖苷酶以提高乙醇生产
CN113278537A (zh) * 2021-06-15 2021-08-20 天津科技大学 系列低产高级醇酿酒酵母及其构建方法与应用
CN114085785A (zh) * 2021-10-29 2022-02-25 湖北冠众通科技有限公司 一种酿酒酵母基因工程菌及其构建方法与应用

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5541084A (en) 1987-06-06 1996-07-30 Robert R. Yocum Hybrid yeast promoter comprising an ENO2 UAS and TATA region and an additional UAS located between said ENO2 UAS and TATA region
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US6004779A (en) 1997-08-22 1999-12-21 Scriptgen Pharmaceuticals, Inc. Regulated gene expression in yeast
AU9386198A (en) 1997-09-10 1999-03-29 President And Fellows Of Harvard College Inducible methods for repressing gene function
EP1135461A4 (en) 1998-12-02 2003-03-26 Univ Boston GENE NETWORKS FOR CONTROLLING GENE EXPRESSION
DE69941223D1 (de) 1998-12-21 2009-09-17 Billig Fritz Chemisch modifizierte enzymen mit mehrfachgeladenen varianten
EP1020515A3 (en) 1999-01-18 2002-08-07 DAICEL CHEMICAL INDUSTRIES, Ltd. Amino alcohol dehydrogenase, its production and use
DE19923950A1 (de) 1999-05-25 2001-01-25 Ulf Stahl Verfahren zur Herstellung von Mikroorganismen mit verändertem Schwefelmetabolismus
SE0002460D0 (sv) 2000-06-29 2000-06-29 Roslyn Bill Modified yeast
WO2002036782A2 (en) 2000-10-30 2002-05-10 Maxygen, Inc. Novel glyphosate n-acetyltransferase (gat) genes
DE10116101B4 (de) 2001-03-30 2005-07-28 Donalies, Ute, Dipl.-Ing. Nukleinsäurekonstrukt und Mikroorganismus mit die Sulfitbildung erhöhenden Sequenzen
EP1526180A1 (en) 2003-10-17 2005-04-27 Stab Vida, Lda. Escola Superior de Biotecnologia/Univ. Catulica Portuguesa Bifunctional gene for mannosylglycerate synthesis
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
EP1869197A2 (en) 2005-04-12 2007-12-26 E.I. Dupont De Nemours And Company Treatment of biomass to obtain ethanol
GB0512707D0 (en) 2005-06-22 2005-07-27 Delta Biotechnology Ltd Gene expression technique
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
EP1948814B1 (en) * 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US20070178505A1 (en) 2006-01-03 2007-08-02 Curt Fischer Promoter engineering and genetic control
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
WO2008013996A2 (en) 2006-07-27 2008-01-31 Gevo Inc. Engineered microorganisms for increasing product yield in biotransformations, related methods and systems
WO2008051854A2 (en) 2006-10-20 2008-05-02 Trustees Of Boston University A tunable genetic switch for regulating gene expression
WO2008119735A1 (en) 2007-04-02 2008-10-09 Georg-August-Universität Göttingen Method of producing hydroxy fatty acids
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US9080187B2 (en) * 2007-05-17 2015-07-14 The Board Of Trustees Of The University Of Illinois Methods and compositions for producing solvents
EP2222841B1 (en) 2007-12-20 2015-08-26 Butamax (TM) Advanced Biofuels LLC Ketol-acid reductoisomerase using nadh
DE102008010121B4 (de) 2008-02-20 2013-11-21 Butalco Gmbh Fermentative Produktion von Isobutanol mit Hefe
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
WO2009143455A2 (en) 2008-05-22 2009-11-26 Microbia, Inc. Engineering resistance to aliphatic alcohols
WO2009149270A2 (en) 2008-06-04 2009-12-10 E. I. Du Pont De Nemours And Company A method for producing butanol using two-phase extractive fermentation
JP2011529345A (ja) * 2008-07-28 2011-12-08 ユニバーシティ オブ マサチューセッツ 微生物における産物の生産を向上させるための方法および組成物
ES2521675T3 (es) 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas
EP2350298A1 (en) 2008-10-27 2011-08-03 ButamaxTM Advanced Biofuels LLC Carbon pathway optimized production hosts for the production of isobutanol
CA2779262C (en) 2008-10-31 2021-09-07 Gevo, Inc. Engineered microorganisms capable of converting pyruvate to isobutanol under anaerobic conditions
WO2010071851A2 (en) 2008-12-20 2010-06-24 The Regents Of University Of California Conversion of co2 to higher alcohols using photosysnthetic microorganisms
US20100272698A1 (en) 2009-02-23 2010-10-28 Lubomira Stateva Yeasts
JP5356140B2 (ja) 2009-07-22 2013-12-04 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー 超音波診断装置及びその制御プログラム
EP2464736A4 (en) 2009-08-12 2013-07-31 Gevo Inc PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL
BR112012006939A2 (pt) 2009-09-29 2015-09-08 Butamax Tm Advanced Biofuels célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides
GB2487889B (en) 2009-11-24 2012-12-19 Gevo Inc Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
EP2519628A2 (en) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
CA2789583C (en) 2010-02-12 2017-01-17 Gevo, Inc. Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
AU2011218090B2 (en) 2010-02-17 2016-06-23 Butamax(Tm) Advanced Biofuels Llc Improving activity of Fe-S cluster requiring proteins
US9193965B2 (en) 2010-04-27 2015-11-24 The Regents Of The University Of California Acetolactate synthase having 2-ketoisovalerate decarboxylase activity and uses thereof
WO2011149353A1 (en) 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
WO2011159894A1 (en) 2010-06-17 2011-12-22 Butamax(Tm) Advanced Biofuels Llc Yeast production culture for the production of butanol
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
EP3269806B1 (en) 2010-09-07 2020-05-27 Butamax (TM) Advanced Biofuels LLC Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
JP6093764B2 (ja) 2011-07-28 2017-03-08 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法

Also Published As

Publication number Publication date
WO2013102147A3 (en) 2013-10-17
KR20140113997A (ko) 2014-09-25
MX2014008073A (es) 2014-10-06
CN104284980A (zh) 2015-01-14
EP2798071A2 (en) 2014-11-05
CA2862450A1 (en) 2013-07-04
JP2015503351A (ja) 2015-02-02
US9181566B2 (en) 2015-11-10
AU2012362144A1 (en) 2014-07-03
BR112014016005A2 (pt) 2017-06-13
US20140004526A1 (en) 2014-01-02
WO2013102147A2 (en) 2013-07-04

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