BR112014016005A8 - alterações genéticas para produção de butanol - Google Patents
alterações genéticas para produção de butanolInfo
- Publication number
- BR112014016005A8 BR112014016005A8 BR112014016005A BR112014016005A BR112014016005A8 BR 112014016005 A8 BR112014016005 A8 BR 112014016005A8 BR 112014016005 A BR112014016005 A BR 112014016005A BR 112014016005 A BR112014016005 A BR 112014016005A BR 112014016005 A8 BR112014016005 A8 BR 112014016005A8
- Authority
- BR
- Brazil
- Prior art keywords
- genetic alterations
- butanol production
- butanol
- production
- genetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01008—Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01043—Phosphogluconate 2-dehydrogenase (1.1.1.43)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01047—Glucose 1-dehydrogenase (1.1.1.47)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01006—Acetolactate synthase (2.2.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01031—6-Phosphogluconolactonase (3.1.1.31)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03009—Glucose-6-phosphatase (3.1.3.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/02—Aldehyde-lyases (4.1.2)
- C12Y401/02009—Phosphoketolase (4.1.2.9)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161581888P | 2011-12-30 | 2011-12-30 | |
PCT/US2012/072186 WO2013102147A2 (en) | 2011-12-30 | 2012-12-28 | Genetic switches for butanol production |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014016005A2 BR112014016005A2 (pt) | 2017-06-13 |
BR112014016005A8 true BR112014016005A8 (pt) | 2017-07-04 |
Family
ID=47559747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014016005A BR112014016005A8 (pt) | 2011-12-30 | 2012-12-28 | alterações genéticas para produção de butanol |
Country Status (10)
Country | Link |
---|---|
US (1) | US9181566B2 (pt) |
EP (1) | EP2798071A2 (pt) |
JP (1) | JP2015503351A (pt) |
KR (1) | KR20140113997A (pt) |
CN (1) | CN104284980A (pt) |
AU (1) | AU2012362144A1 (pt) |
BR (1) | BR112014016005A8 (pt) |
CA (1) | CA2862450A1 (pt) |
MX (1) | MX2014008073A (pt) |
WO (1) | WO2013102147A2 (pt) |
Families Citing this family (38)
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US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
NZ579780A (en) | 2007-04-18 | 2012-07-27 | Butamax Advanced Biofuels Llc | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
EP2337856A1 (en) | 2008-09-29 | 2011-06-29 | Butamax Advanced Biofuels Llc | INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST |
EP2519628A2 (en) | 2009-12-29 | 2012-11-07 | Butamax (TM) Advanced Biofuels LLC | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
AU2011218090B2 (en) | 2010-02-17 | 2016-06-23 | Butamax(Tm) Advanced Biofuels Llc | Improving activity of Fe-S cluster requiring proteins |
EP3269806B1 (en) | 2010-09-07 | 2020-05-27 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
US9790521B2 (en) | 2011-03-24 | 2017-10-17 | Butamax Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
JP6093764B2 (ja) | 2011-07-28 | 2017-03-08 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法 |
EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
WO2013142338A1 (en) | 2012-03-23 | 2013-09-26 | Butamax(Tm) Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
CA2873109A1 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
US9593349B2 (en) | 2012-08-22 | 2017-03-14 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
WO2014106107A2 (en) * | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
HUE045200T2 (hu) | 2013-03-14 | 2019-12-30 | Du Pont | Glicerin-3-foszfát dehidrogenáz butanol elõállítására |
US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
WO2015002913A1 (en) | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
WO2015002919A2 (en) * | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Regulation of production pathways in host cells |
WO2015009601A1 (en) * | 2013-07-16 | 2015-01-22 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall proteins |
JP2015128397A (ja) * | 2014-01-08 | 2015-07-16 | 国立大学法人広島大学 | 亜リン酸デヒドロゲナーゼ遺伝子、および、当該遺伝子を用いた出芽酵母の選択的培養方法 |
CA2957920A1 (en) * | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
PT3237601T (pt) * | 2014-12-23 | 2020-08-20 | Carlsberg Breweries As | Levedura para preparação de bebidas alcoólicas |
WO2016205753A1 (en) * | 2015-06-17 | 2016-12-22 | The Translational Genomics Research Institute | Systems and methods for obtaining biological molecules from a sample |
WO2017216136A1 (en) * | 2016-06-14 | 2017-12-21 | Dsm Ip Assets B.V. | Recombinant yeast cell |
WO2018132512A1 (en) * | 2017-01-10 | 2018-07-19 | Massachusetts Institute Of Technology | Constructs and cells for enhanced protein expression |
MX2019009032A (es) * | 2017-01-30 | 2019-09-10 | Intrexon Corp | Metodos y microorganismos para elaborar 2,3-butandiol y derivados de los mismos a partir de carbonos c1. |
WO2018200894A1 (en) * | 2017-04-28 | 2018-11-01 | Intrexon Corporation | Methods and microorganisms for the fermentation of methane to multi-carbon compounds |
CN107177623B (zh) * | 2017-05-24 | 2020-01-07 | 梁恒宇 | 一种高产甘油低产乙酸的葡萄酒用酿酒酵母菌株及构建方法 |
CN108226367A (zh) * | 2017-12-29 | 2018-06-29 | 青岛啤酒股份有限公司 | 一种啤酒中丙三醇的检测方法 |
HUE062297T2 (hu) * | 2019-01-29 | 2023-10-28 | Clariant Produkte Deutschland Gmbh | Kiméra promóter anyagcsere módosítási alkalmazásra |
CN110551644A (zh) * | 2019-07-19 | 2019-12-10 | 天津科技大学 | 通过调控细胞壁组成蛋白构建的低产高级醇酿酒酵母菌株 |
CN114555778A (zh) | 2019-08-29 | 2022-05-27 | 丹尼斯科美国公司 | 在酵母中表达β-葡糖苷酶以提高乙醇生产 |
CN113278537A (zh) * | 2021-06-15 | 2021-08-20 | 天津科技大学 | 系列低产高级醇酿酒酵母及其构建方法与应用 |
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EP3269806B1 (en) | 2010-09-07 | 2020-05-27 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
US9790521B2 (en) | 2011-03-24 | 2017-10-17 | Butamax Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
JP6093764B2 (ja) | 2011-07-28 | 2017-03-08 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法 |
-
2012
- 2012-12-28 AU AU2012362144A patent/AU2012362144A1/en not_active Abandoned
- 2012-12-28 JP JP2014550527A patent/JP2015503351A/ja active Pending
- 2012-12-28 EP EP12815979.5A patent/EP2798071A2/en not_active Withdrawn
- 2012-12-28 CA CA2862450A patent/CA2862450A1/en not_active Abandoned
- 2012-12-28 CN CN201280070983.5A patent/CN104284980A/zh active Pending
- 2012-12-28 KR KR1020147021289A patent/KR20140113997A/ko not_active Application Discontinuation
- 2012-12-28 BR BR112014016005A patent/BR112014016005A8/pt not_active Application Discontinuation
- 2012-12-28 MX MX2014008073A patent/MX2014008073A/es unknown
- 2012-12-28 WO PCT/US2012/072186 patent/WO2013102147A2/en active Application Filing
- 2012-12-28 US US13/730,742 patent/US9181566B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2013102147A3 (en) | 2013-10-17 |
KR20140113997A (ko) | 2014-09-25 |
MX2014008073A (es) | 2014-10-06 |
CN104284980A (zh) | 2015-01-14 |
EP2798071A2 (en) | 2014-11-05 |
CA2862450A1 (en) | 2013-07-04 |
JP2015503351A (ja) | 2015-02-02 |
US9181566B2 (en) | 2015-11-10 |
AU2012362144A1 (en) | 2014-07-03 |
BR112014016005A2 (pt) | 2017-06-13 |
US20140004526A1 (en) | 2014-01-02 |
WO2013102147A2 (en) | 2013-07-04 |
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