BR112014008616A2 - compostos antivirais - Google Patents

compostos antivirais

Info

Publication number
BR112014008616A2
BR112014008616A2 BR112014008616A BR112014008616A BR112014008616A2 BR 112014008616 A2 BR112014008616 A2 BR 112014008616A2 BR 112014008616 A BR112014008616 A BR 112014008616A BR 112014008616 A BR112014008616 A BR 112014008616A BR 112014008616 A2 BR112014008616 A2 BR 112014008616A2
Authority
BR
Brazil
Prior art keywords
compounds
formulas
antiviral compounds
antiviral
variables
Prior art date
Application number
BR112014008616A
Other languages
English (en)
Inventor
Li Hongju
A Brinkman John
Sarabu Ramakanth
So Sung-Sau
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112014008616A2 publication Critical patent/BR112014008616A2/pt

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L3/00—Supports for pipes, cables or protective tubing, e.g. hangers, holders, clamps, cleats, clips, brackets
    • F16L3/26—Supports for pipes, cables or protective tubing, e.g. hangers, holders, clamps, cleats, clips, brackets specially adapted for supporting the pipes all along their length, e.g. pipe channels or ducts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Abstract

resumo compostos antivirais a presente invenção descreve compostos de fórmulas i e ii, em que as variáveis nas fórmulas i e ii são definidas como descrito aqui. também são divulgadas composições farmacêuticas que contêm tais compostos e métodos, para uso dos referidos compostos de fórmulas i e ii, no tratamento de infecção pelo hcv.
BR112014008616A 2011-10-10 2012-10-08 compostos antivirais BR112014008616A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161545216P 2011-10-10 2011-10-10
PCT/EP2012/069811 WO2013053657A1 (en) 2011-10-10 2012-10-08 Antiviral compounds

Publications (1)

Publication Number Publication Date
BR112014008616A2 true BR112014008616A2 (pt) 2017-04-18

Family

ID=46980962

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014008616A BR112014008616A2 (pt) 2011-10-10 2012-10-08 compostos antivirais

Country Status (11)

Country Link
US (2) US9180193B2 (pt)
EP (1) EP2766365A1 (pt)
JP (1) JP5808496B2 (pt)
KR (1) KR101621181B1 (pt)
CN (1) CN103917541B (pt)
BR (1) BR112014008616A2 (pt)
CA (1) CA2847083A1 (pt)
HK (1) HK1199454A1 (pt)
MX (1) MX2014003705A (pt)
RU (1) RU2014117587A (pt)
WO (1) WO2013053657A1 (pt)

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US9717712B2 (en) 2013-07-02 2017-08-01 Bristol-Myers Squibb Company Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus
EP3021845A1 (en) 2013-07-17 2016-05-25 Bristol-Myers Squibb Company Combinations comprising biphenyl derivatives for use in the treatment of hcv
WO2017023631A1 (en) 2015-08-06 2017-02-09 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
WO2017197046A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. C3-carbon linked glutarimide degronimers for target protein degradation
CN109562113A (zh) 2016-05-10 2019-04-02 C4医药公司 用于靶蛋白降解的螺环降解决定子体
EP3454856A4 (en) 2016-05-10 2019-12-25 C4 Therapeutics, Inc. HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN REDUCTION
WO2018224455A1 (en) 2017-06-07 2018-12-13 Basf Se Substituted cyclopropyl derivatives

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Also Published As

Publication number Publication date
MX2014003705A (es) 2014-07-22
CA2847083A1 (en) 2013-04-18
EP2766365A1 (en) 2014-08-20
JP2014528439A (ja) 2014-10-27
HK1199454A1 (en) 2015-07-03
CN103917541A (zh) 2014-07-09
US20140255344A1 (en) 2014-09-11
US9180193B2 (en) 2015-11-10
RU2014117587A (ru) 2015-11-20
JP5808496B2 (ja) 2015-11-10
CN103917541B (zh) 2016-08-17
KR101621181B1 (ko) 2016-05-13
WO2013053657A1 (en) 2013-04-18
KR20140076620A (ko) 2014-06-20
US20160169418A1 (en) 2016-06-16
US10215310B2 (en) 2019-02-26

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2483 DE 07-08-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.