BR112013013282A2 - compostos de oxazolo[5,4-b]piridin-5-ila - Google Patents

compostos de oxazolo[5,4-b]piridin-5-ila

Info

Publication number
BR112013013282A2
BR112013013282A2 BR112013013282A BR112013013282A BR112013013282A2 BR 112013013282 A2 BR112013013282 A2 BR 112013013282A2 BR 112013013282 A BR112013013282 A BR 112013013282A BR 112013013282 A BR112013013282 A BR 112013013282A BR 112013013282 A2 BR112013013282 A2 BR 112013013282A2
Authority
BR
Brazil
Prior art keywords
oxazolo
pyridin
compounds
Prior art date
Application number
BR112013013282A
Other languages
English (en)
Inventor
David Andrew Coates
Eva Maria Martin De La Nava
Jose Alfredo Martin
Raymond Gilmour
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46162794&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013013282(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR112013013282A2 publication Critical patent/BR112013013282A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
BR112013013282A 2010-12-03 2011-11-17 compostos de oxazolo[5,4-b]piridin-5-ila BR112013013282A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10382329 2010-12-03
US201161439151P 2011-02-03 2011-02-03
PCT/US2011/061099 WO2012074761A1 (en) 2010-12-03 2011-11-17 Oxazolo [5, 4 -b] pyridin- 5 -yl compounds and their use for the treatment of cancer

Publications (1)

Publication Number Publication Date
BR112013013282A2 true BR112013013282A2 (pt) 2016-09-06

Family

ID=46162794

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013013282A BR112013013282A2 (pt) 2010-12-03 2011-11-17 compostos de oxazolo[5,4-b]piridin-5-ila

Country Status (26)

Country Link
US (1) US8288548B2 (pt)
EP (1) EP2646445B1 (pt)
JP (1) JP5726321B2 (pt)
KR (1) KR101514162B1 (pt)
CN (1) CN103221415B (pt)
AR (1) AR083868A1 (pt)
AU (1) AU2011337033A1 (pt)
BR (1) BR112013013282A2 (pt)
CA (1) CA2819822C (pt)
CL (1) CL2013001518A1 (pt)
CO (1) CO6761387A2 (pt)
CR (1) CR20130182A (pt)
DO (1) DOP2013000116A (pt)
EA (1) EA021241B1 (pt)
EC (1) ECSP13012653A (pt)
ES (1) ES2567271T3 (pt)
GT (1) GT201300139A (pt)
IL (1) IL226054A0 (pt)
MX (1) MX2013006184A (pt)
NZ (1) NZ610289A (pt)
PE (1) PE20140008A1 (pt)
SG (1) SG190680A1 (pt)
TW (1) TWI410425B (pt)
UA (1) UA109677C2 (pt)
WO (1) WO2012074761A1 (pt)
ZA (1) ZA201303580B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102279347B1 (ko) 2016-12-15 2021-07-21 한국생명공학연구원 피리딘계 화합물을 유효성분으로 함유하는 dyrk 관련 질환의 예방 또는 치료용 약학적 조성물
PT3691620T (pt) 2017-10-05 2022-10-06 Fulcrum Therapeutics Inc Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ520640A (en) 2000-02-15 2005-04-29 Upjohn Co Pyrrole substituted 2-indolinone protein kinase inhibitors
AR029803A1 (es) * 2000-02-21 2003-07-16 Smithkline Beecham Plc Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden
CA2440211A1 (en) * 2001-03-09 2002-09-19 Pfizer Products Inc. Benzimidazole anti-inflammatory compounds
DE60309342T2 (de) * 2002-08-09 2007-05-16 Eli Lilly And Co., Indianapolis Benzimidazole und benzothiazole als inhibitoren der map-kinase
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors
EP1781293A1 (en) 2004-06-04 2007-05-09 Amphora Discovery Corporation Quinoline- and isoquinoline-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
US7723340B2 (en) 2005-01-13 2010-05-25 Signal Pharmaceuticals, Llc Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
US7473784B2 (en) * 2005-08-01 2009-01-06 Bristol-Myers Squibb Company Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors
WO2009017822A2 (en) 2007-08-02 2009-02-05 Amgen Inc. Pi3 kinase modulators and methods of use

Also Published As

Publication number Publication date
ES2567271T3 (es) 2016-04-21
IL226054A0 (en) 2013-06-27
GT201300139A (es) 2014-04-08
SG190680A1 (en) 2013-07-31
WO2012074761A1 (en) 2012-06-07
ECSP13012653A (es) 2013-08-30
ZA201303580B (en) 2014-12-23
EP2646445A1 (en) 2013-10-09
CN103221415A (zh) 2013-07-24
MX2013006184A (es) 2013-07-15
KR20130093140A (ko) 2013-08-21
CL2013001518A1 (es) 2013-11-04
CA2819822A1 (en) 2012-06-07
AR083868A1 (es) 2013-03-27
EP2646445B1 (en) 2016-03-16
CO6761387A2 (es) 2013-09-30
AU2011337033A1 (en) 2013-07-18
JP5726321B2 (ja) 2015-05-27
EA201390620A1 (ru) 2013-10-30
CN103221415B (zh) 2015-06-17
PE20140008A1 (es) 2014-01-31
TW201300397A (zh) 2013-01-01
KR101514162B1 (ko) 2015-04-21
TWI410425B (zh) 2013-10-01
DOP2013000116A (es) 2014-10-31
NZ610289A (en) 2015-07-31
JP2013544835A (ja) 2013-12-19
CR20130182A (es) 2013-07-09
US20120142724A1 (en) 2012-06-07
CA2819822C (en) 2015-07-21
EA021241B1 (ru) 2015-05-29
UA109677C2 (ru) 2015-09-25
US8288548B2 (en) 2012-10-16

Similar Documents

Publication Publication Date Title
IL234485A (en) Compounds based on imidazo [2,1 – b] pyridazine
BRPI0919948A2 (pt) Pirido[4,3-b]indois contendo porções rígidas
BR112012028519A2 (pt) compostos de 2,5,6,7-tetrahidro-[1,4]oxazepin-3-ilamina ou 2,3,6,7-tetrahidro-[1,4]oxazepin-5-ilamina
AP2806A (en) 3H-imidazo[4,5-C] pyridine-6-carboxamides as anti-infammatory agents
HK1184780A1 (en) Isoxazoline derivatives as antiparasitic agents
EP2681216A4 (en) SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS CONDENSED IN 6.5
PH12013501402A1 (en) Mesoionic Pyrido [1,2 -A] Pyrimidine Pesticides
BRPI0919292A2 (pt) 3h-imidazo[4,5-b] piridina-6-carboxamidas como agentes anti-inflamatórios
IL227496B (en) Pyrazolo[4,3–b]pyridines are converted as drugs
ZA201307783B (en) Tri-and tetracylic pyrazolo[3,4-b]pyridine compounds as antineoplastic agent
PT2531492T (pt) Derivados 1,2,4-triazina4-amina
ZA201206630B (en) Hetaryl-[1,8]naphthyridine derivatives
EP2634186A4 (en) naphthyridine
IL229993A (en) 8 - Alkoxy [1,2,4] triazolo [5,1 – c] pyrimidine– 2
BRPI1014459A2 (pt) derivados de 3-(1,2,3-triazol-4-il)pirrolo[2,3-b]-piridina"
AP2013007147A0 (en) Use of substituted 2,3-dihydroimidazo[1,2-C]quinyzolines
ZA201208616B (en) Substituted 2,3-dihydroimidazo[1,2-c]quinazoline-containing combinations
BR112013013912A2 (pt) compostos de triazolopiridina
IL221479A0 (en) Triazolo [4,5-b] pyridin derivatives
IL232717B (en) 3-cyanoaryl-h1-pyrrolo[b-3,2]pyridine derivatives
ZA201301313B (en) Herbicidal isoxazolo[5,4-b]pyridines
BR112013013282A2 (pt) compostos de oxazolo[5,4-b]piridin-5-ila
EP2565194A4 (en) Imidazo [1,2-A] pyridine
HK1185882A1 (en) Pyrazino[2,3-d]isoxazole derivative [23-d]
PT2729473E (pt) Derivados de ácido carboxílico com um anel oxazolo[5,4-b]piridina

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]