BR1100019A - Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos - Google Patents

Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos

Info

Publication number
BR1100019A
BR1100019A BR1100019-8A BR1100019A BR1100019A BR 1100019 A BR1100019 A BR 1100019A BR 1100019 A BR1100019 A BR 1100019A BR 1100019 A BR1100019 A BR 1100019A
Authority
BR
Brazil
Prior art keywords
compounds
peptide
pharmaceutical composition
preparing
preparing compounds
Prior art date
Application number
BR1100019-8A
Other languages
English (en)
Inventor
Andreas Haupt
Bernd Janssen
Kurt Ritter
Dagmar Klinge
Gerhard Keilhauer
Cynthia Romerdahl
Teresa Barlozzari
Xiao-Dong Qian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to BR1100019-8A priority Critical patent/BR1100019A/pt
Publication of BR1100019A publication Critical patent/BR1100019A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Window Of Vehicle (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BR1100019-8A 1992-12-16 1996-07-26 Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos BR1100019A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR1100019-8A BR1100019A (pt) 1992-12-16 1996-07-26 Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99130992A 1992-12-16 1992-12-16
BR1100019-8A BR1100019A (pt) 1992-12-16 1996-07-26 Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos

Publications (1)

Publication Number Publication Date
BR1100019A true BR1100019A (pt) 2000-07-25

Family

ID=25537082

Family Applications (1)

Application Number Title Priority Date Filing Date
BR1100019-8A BR1100019A (pt) 1992-12-16 1996-07-26 Peptìdeo, compostos, composição farmacêutica, e, método de preparar compostos

Country Status (24)

Country Link
US (1) US5502032A (pt)
EP (1) EP0674652B1 (pt)
JP (1) JPH08504415A (pt)
CN (1) CN1057095C (pt)
AT (1) ATE196296T1 (pt)
AU (1) AU679479B2 (pt)
BR (1) BR1100019A (pt)
CA (1) CA2151953A1 (pt)
CZ (1) CZ286752B6 (pt)
DE (1) DE69329425T2 (pt)
ES (1) ES2151921T3 (pt)
FI (1) FI952961A0 (pt)
HR (1) HRP931504B1 (pt)
HU (1) HUT72067A (pt)
IL (1) IL107987A (pt)
NO (1) NO952366D0 (pt)
NZ (1) NZ258882A (pt)
PL (1) PL178766B1 (pt)
RU (1) RU2132334C1 (pt)
SG (1) SG67935A1 (pt)
SI (1) SI9300661A (pt)
TW (1) TW400335B (pt)
WO (1) WO1994013695A1 (pt)
ZA (1) ZA939389B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599902A (en) * 1994-11-10 1997-02-04 Arizona Board Of Regents Acting On Behalf Of Arizona State University Cancer inhibitory peptides
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
US20010009901A1 (en) * 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US5741892A (en) * 1996-07-30 1998-04-21 Basf Aktiengesellschaft Pentapeptides as antitumor agents
US5939527A (en) * 1996-07-30 1999-08-17 Basf Aktiengesellschaft Tetrapeptides as antitumor agents
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US6103698A (en) * 1997-03-13 2000-08-15 Basf Aktiengesellschaft Dolastatin-15 derivatives in combination with taxanes
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
US6015790A (en) * 1997-10-06 2000-01-18 Basf Aktiengesellschaft Methods and compositions for treating rheumatoid arthritis
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
EP1156803A4 (en) 1999-02-09 2004-03-17 Bristol Myers Squibb Co FXA LACTAM INHIBITORS AND METHOD
US6323315B1 (en) 1999-09-10 2001-11-27 Basf Aktiengesellschaft Dolastatin peptides
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US6511973B2 (en) 2000-08-02 2003-01-28 Bristol-Myers Squibb Co. Lactam inhibitors of FXa and method
CA2436774A1 (en) * 2001-01-30 2002-08-08 R. Michael Lawrence Sulfonamide lactam inhibitors of factor xa
EP1446110A2 (en) * 2001-10-16 2004-08-18 Structural Bioinformatics Inc. Organosulfur inhibitors of tyrosine phosphatases
US7087604B2 (en) 2002-03-08 2006-08-08 Bristol-Myers Squibb Company Cyclic derivatives as modulators of chemokine receptor activity
JP2006525990A (ja) * 2003-05-12 2006-11-16 ファイザー・プロダクツ・インク 神経変性障害の処置のためのイソオキサゾール化合物およびイソチアゾール化合物
JP2008503490A (ja) * 2004-06-17 2008-02-07 センジェント・セラピューティクス・インコーポレイテッド チロシンホスファターゼの三置換窒素調節物質
EP1786421A2 (en) * 2004-07-09 2007-05-23 Cengent Therapeutics, Inc. Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases
EP1841749A1 (en) 2004-09-02 2007-10-10 Metabasis Therapeutics, Inc. Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
EP2722051B1 (en) 2005-07-07 2018-11-07 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus
RU2617402C2 (ru) 2011-06-10 2017-04-25 Мерсана Терапьютикс, Инк. Конъюгаты белок-полимер-лекарственное средство
EP2928503B1 (en) 2012-12-10 2019-02-20 Mersana Therapeutics, Inc. Conjugates of auristatin compounds
CN105358174B (zh) 2013-03-15 2019-03-15 酵活有限公司 具细胞毒性和抗有丝***的化合物以及其使用方法
PL3086815T3 (pl) 2013-12-27 2022-06-13 Zymeworks Inc. Układy łącznikowe dla koniugatów leków zawierające ugrupowanie sulfonamidowe
US10675355B2 (en) 2013-12-27 2020-06-09 Var2 Pharmaceuticals Aps VAR2CSA-drug conjugates
WO2016041082A1 (en) 2014-09-17 2016-03-24 CDRD Ventures, Inc. Cytotoxic and anti-mitotic compounds, and methods of using the same
US10517958B2 (en) 2016-10-04 2019-12-31 Zymeworks Inc. Compositions and methods for the treatment of platinum-drug resistant cancer
JPWO2023033129A1 (pt) 2021-09-03 2023-03-09

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3540495A1 (de) * 1985-11-15 1987-05-21 Merck Patent Gmbh Aminosaeurederivate
ES2058070T3 (es) * 1986-05-09 1994-11-01 Pulverer Gerhard Utilizacion de monosacaridos especificos para la preparacion de un medicamento para impedir metastasis de tumores malignos.
JP2714402B2 (ja) * 1988-07-13 1998-02-16 日清製粉株式会社 癌転移抑制剤
EP0357332A3 (en) * 1988-08-24 1991-07-31 Merck & Co. Inc. Renin inhibitors useful for the treatment of aids by inhibition of hiv protease
US4978744A (en) * 1989-01-27 1990-12-18 Arizona Board Of Regents Synthesis of dolastatin 10
US5138036A (en) * 1989-11-13 1992-08-11 Arizona Board Of Regents Acting On Behalf Of Arizona State University Isolation and structural elucidation of the cytostatic cyclodepsipeptide dolastatin 14
SG87056A1 (en) * 1991-08-09 2002-03-19 Teikoku Hormone Mfg Co Ltd Novel tetrapeptide derivative

Also Published As

Publication number Publication date
CZ157595A3 (en) 1996-01-17
SI9300661A (en) 1994-06-30
ES2151921T3 (es) 2001-01-16
HRP931504A2 (en) 1997-02-28
HU9501754D0 (en) 1995-08-28
EP0674652B1 (en) 2000-09-13
CN1095724A (zh) 1994-11-30
US5502032A (en) 1996-03-26
RU2132334C1 (ru) 1999-06-27
CZ286752B6 (en) 2000-06-14
AU5695994A (en) 1994-07-04
JPH08504415A (ja) 1996-05-14
PL178766B1 (pl) 2000-06-30
TW400335B (en) 2000-08-01
CN1057095C (zh) 2000-10-04
PL309353A1 (en) 1995-10-02
FI952961A (fi) 1995-06-15
FI952961A0 (fi) 1995-06-15
IL107987A (en) 1999-10-28
ZA939389B (en) 1995-06-15
NO952366L (no) 1995-06-15
NZ258882A (en) 1997-06-24
HRP931504B1 (en) 2001-04-30
DE69329425D1 (de) 2000-10-19
ATE196296T1 (de) 2000-09-15
HUT72067A (en) 1996-03-28
NO952366D0 (no) 1995-06-15
CA2151953A1 (en) 1994-06-23
RU95115135A (ru) 1997-06-10
DE69329425T2 (de) 2001-01-18
IL107987A0 (en) 1994-04-12
SG67935A1 (en) 1999-10-19
AU679479B2 (en) 1997-07-03
EP0674652A1 (en) 1995-10-04
WO1994013695A1 (en) 1994-06-23

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Legal Events

Date Code Title Description
MT Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96
FGAN Processing applications according to articles 230 and 231 of law 9.279/96: granting
NB Patent issued - articles 230 and 231 of law 9279/96