BR0213562A - Benzimidazoles and analogs and their use as protein kinase inhibitors - Google Patents

Benzimidazoles and analogs and their use as protein kinase inhibitors

Info

Publication number
BR0213562A
BR0213562A BR0213562-0A BR0213562A BR0213562A BR 0213562 A BR0213562 A BR 0213562A BR 0213562 A BR0213562 A BR 0213562A BR 0213562 A BR0213562 A BR 0213562A
Authority
BR
Brazil
Prior art keywords
compounds
analogs
protein kinase
kinase inhibitors
benzimidazoles
Prior art date
Application number
BR0213562-0A
Other languages
Portuguese (pt)
Inventor
Michael Louis Edwards
Paul Joseph Cox
Shelley Amendola
Stephanie Daniele Deprets
Timothy Alan Gillespy
Christopher David Edlin
Andrew David Morley
Charles J Gardner
Brian Pedgrift
Herve Bouchard
Didier Babin
Laurence Gauzy
Alain Brunet
Alain Le Brun
Tahir Nedeem Majid
John C Reader
Lloyd J Payne
Nawaz M Khan
Michael Cherry
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0113868A external-priority patent/FR2831537B1/en
Priority claimed from GB0206893A external-priority patent/GB0206893D0/en
Priority claimed from GB0206895A external-priority patent/GB0206895D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BR0213562A publication Critical patent/BR0213562A/en

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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Abstract

"BENZIMIDAZóIS E ANáLOGOS E SEU USO COMO INIBIDORES DE CINASES DE PROTEìNA". A invenção refere-se a compostos fisiologicamente ativos da fórmula geral (Ix) e composições contendo tais compostos, e suas pró-drogas, e sais e solvatos farmaceuticamente aceitáveis de tais compostos e suas pró-drogas, bem como a novos compostos dentro do escopo da fórmula (Ix), e a processos para sua preparação. Tais compostos e composições têm propriedades farmacêuticas valiosas, em particular a habilidade de inibir cinases."BENZIMIDAZOLS AND ANALOGS AND THEIR USE AS PROTEIN KINASE INHIBITORS". The invention relates to physiologically active compounds of general formula (Ix) and compositions containing such compounds, and prodrugs thereof, and pharmaceutically acceptable salts and solvates of such compounds and prodrugs thereof, as well as to novel compounds within the scope. of formula (Ix), and processes for their preparation. Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

BR0213562-0A 2001-10-26 2002-10-24 Benzimidazoles and analogs and their use as protein kinase inhibitors BR0213562A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR0113868A FR2831537B1 (en) 2001-10-26 2001-10-26 NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF
GB0206893A GB0206893D0 (en) 2002-03-22 2002-03-22 Chemical compounds
GB0206895A GB0206895D0 (en) 2002-03-22 2002-03-22 Chemical compounds
US39506002P 2002-07-11 2002-07-11
US39515102P 2002-07-11 2002-07-11
PCT/GB2002/004763 WO2003035065A1 (en) 2001-10-26 2002-10-24 Benzimidazoles and analogues and their use as protein kinases inhibitors

Publications (1)

Publication Number Publication Date
BR0213562A true BR0213562A (en) 2004-08-31

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Family Applications (1)

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BR0213562-0A BR0213562A (en) 2001-10-26 2002-10-24 Benzimidazoles and analogs and their use as protein kinase inhibitors

Country Status (9)

Country Link
EP (1) EP1441725A1 (en)
JP (1) JP5039268B2 (en)
AU (1) AU2002334217B2 (en)
BR (1) BR0213562A (en)
CA (1) CA2465247C (en)
IL (1) IL161576A0 (en)
MX (1) MXPA04003954A (en)
UY (1) UY27516A1 (en)
WO (1) WO2003035065A1 (en)

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