FR2831537B1 - NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF - Google Patents
NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOFInfo
- Publication number
- FR2831537B1 FR2831537B1 FR0113868A FR0113868A FR2831537B1 FR 2831537 B1 FR2831537 B1 FR 2831537B1 FR 0113868 A FR0113868 A FR 0113868A FR 0113868 A FR0113868 A FR 0113868A FR 2831537 B1 FR2831537 B1 FR 2831537B1
- Authority
- FR
- France
- Prior art keywords
- medicaments
- preparation
- pharmaceutical compositions
- benzimidazole derivatives
- novel benzimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0113868A FR2831537B1 (en) | 2001-10-26 | 2001-10-26 | NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF |
IL16157602A IL161576A0 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors |
BR0213562-0A BR0213562A (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogs and their use as protein kinase inhibitors |
JP2003537632A JP5039268B2 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogs and their use as protein kinase inhibitors |
HN2002000311A HN2002000311A (en) | 2001-10-26 | 2002-10-24 | BENZOIMIDAZOLES |
CA2465247A CA2465247C (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors |
PCT/GB2002/004763 WO2003035065A1 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors |
MXPA04003954A MXPA04003954A (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors. |
EP02801954A EP1441725A1 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors |
AU2002334217A AU2002334217B2 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles and analogues and their use as protein kinases inhibitors |
US10/279,834 US6897208B2 (en) | 2001-10-26 | 2002-10-24 | Benzimidazoles |
PA20028557101A PA8557101A1 (en) | 2001-10-26 | 2002-10-25 | BENZIMIDAZOLES |
ARP020104061A AR037032A1 (en) | 2001-10-26 | 2002-10-25 | BENZOIMIDAZOLES |
SV2002001369A SV2008001369A (en) | 2001-10-26 | 2002-10-25 | BENZIMIDAZOLES |
GT200200219A GT200200219A (en) | 2001-10-26 | 2002-10-25 | BENCIMIDAZOLS |
UY27516A UY27516A1 (en) | 2001-10-26 | 2002-10-25 | BENCIMIDAZOLS |
PE2002001052A PE20030612A1 (en) | 2001-10-26 | 2002-10-25 | BENZOIMIDAZOLES |
JO2002108A JO2339B1 (en) | 2001-10-26 | 2002-10-27 | Benzimidazoles |
US11/029,064 US8288425B2 (en) | 2001-10-26 | 2005-01-04 | Benzimidazoles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0113868A FR2831537B1 (en) | 2001-10-26 | 2001-10-26 | NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2831537A1 FR2831537A1 (en) | 2003-05-02 |
FR2831537B1 true FR2831537B1 (en) | 2008-02-29 |
Family
ID=8868756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0113868A Expired - Fee Related FR2831537B1 (en) | 2001-10-26 | 2001-10-26 | NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2831537B1 (en) |
GT (1) | GT200200219A (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2854159B1 (en) * | 2003-04-25 | 2008-01-11 | Aventis Pharma Sa | NOVEL INDOLE DERIVATIVES, THEIR PREPARATION AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS KDR INHIBITORS |
FR2857363B1 (en) * | 2003-07-10 | 2007-09-07 | Aventis Pharma Sa | SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO [3,4-C] PYRIDINES COMPOSITIONS CONTAINING SAME AND USE THEREOF |
AR045037A1 (en) * | 2003-07-10 | 2005-10-12 | Aventis Pharma Sa | TETRAHIDRO-1H-PIRAZOLO [3,4-C] SUBSTITUTED PYRIDINS, COMPOSITIONS THAT CONTAIN THEM AND ITS USE. |
BR112012000254A2 (en) | 2009-07-08 | 2016-02-16 | Dermira Canada Inc | tofa analogues useful in treating dermatological disorders or conditions. |
KR101529767B1 (en) | 2009-08-07 | 2015-06-17 | 추가이 세이야쿠 가부시키가이샤 | Aminopyrazole derivative |
EP3581179A1 (en) | 2013-12-27 | 2019-12-18 | Chugai Seiyaku Kabushiki Kaisha | Fgfr gatekeeper mutant gene and drug targeting same |
US10479780B2 (en) | 2015-06-17 | 2019-11-19 | Chugai Seiyaku Kabushiki Kaisha | Aminopyrazole derivatives |
EP3296297A1 (en) * | 2016-09-15 | 2018-03-21 | Centre National De La Recherche Scientifique | Benzimidazol derivatives for treating filovirus infection |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2130029A1 (en) * | 1971-06-18 | 1972-12-21 | Bayer Ag | Anthelmintic 2-pyrazolyl-benzimidazoles prodn - from 2-hydroxy -benzimidazoles and pyrazoles with phosphorus halides |
DE2130030A1 (en) * | 1971-06-18 | 1972-12-21 | Bayer Ag | Fungicidal and bactericidal agents |
BE793501A (en) * | 1971-12-31 | 1973-06-29 | Ciba Geigy | HETEROCYCLIC COMPOUNDS AND PHYTOPHARMACEUTICAL PRODUCTS WHICH CONTAIN IT |
JP4357004B2 (en) * | 1997-04-11 | 2009-11-04 | あすか製薬株式会社 | Pyrazole derivative and COX inhibitor containing the same |
CN1168727C (en) * | 1999-06-23 | 2004-09-29 | 阿文蒂斯药物德国有限公司 | Substituted benzimidazole |
PE20010306A1 (en) * | 1999-07-02 | 2001-03-29 | Agouron Pharma | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM USEFUL FOR THE INHIBITION OF PROTEIN KINASE |
YU54202A (en) * | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Indazole compounds,pharmaceutical compositions,and methods for mediating or inhibiting cell proliferation |
-
2001
- 2001-10-26 FR FR0113868A patent/FR2831537B1/en not_active Expired - Fee Related
-
2002
- 2002-10-25 GT GT200200219A patent/GT200200219A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2831537A1 (en) | 2003-05-02 |
GT200200219A (en) | 2003-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20160630 |