BR0208202A - ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit - Google Patents

ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit

Info

Publication number
BR0208202A
BR0208202A BR0208202-0A BR0208202A BR0208202A BR 0208202 A BR0208202 A BR 0208202A BR 0208202 A BR0208202 A BR 0208202A BR 0208202 A BR0208202 A BR 0208202A
Authority
BR
Brazil
Prior art keywords
sequence
lipid
fatty acid
organism
acid
Prior art date
Application number
BR0208202-0A
Other languages
English (en)
Inventor
Johnathan A Napier
Colin M Lazarus
Baoxiu Qi
Jens Lerchl
Original Assignee
Univ Bristol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bristol filed Critical Univ Bristol
Publication of BR0208202A publication Critical patent/BR0208202A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Edible Oils And Fats (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)

Abstract

"áCIDO NUCLEICO ISOLADO, SEQuêNCIA DE AMINOáCIDOS, CONSTRUçãO DE GENE, VETOR, ORGANISMO, PROCESSO PARA A PRODUçãO DE PUFAS, óLEO, LIPìDEO OU áCIDO GRAXO OU FRAçãO DESTES, COMPOSIçãO OLEAGINOSA, LIPìDICA OU DE áCIDOS GRAXOS, USO DA MESMA, ANTICORPO, SEQuêNCIA DE NUCLEOTìDEOS ANTI-SENTIDO, E, KIT". A invenção diz respeito a um novo gene elongase tendo a seq³ência SEQ ID NO: 1 ou seus derivados, a uma construção de gene que compreende esta seq³ência ou seus derivados, e a seu uso. A seq³ência de ácido nucleico inventiva codifica um polipeptídeo que alonga o ácido <244>-linolênico (C~ 18:3 d9,12,15~) em pelo menos dois átomos de carbono, enquanto o ácido <sym>-linolênico (C~ 18:3 d6, 9, 12~) não é alongado. A invenção adicionalmente diz respeito a vetores ou organismos que compreendem um gene elongase tendo a seq³ência SEQ ID NO: 1 ou seus derivados. A invenção ainda diz respeito a um processo para a produção de ácidos graxos poliinsaturados (=PUFAs) com um organismo que compreende o gene elongase, organismo este que produz altas quantidades de óleos e, especialmente, óleos com um alto teor de ácidos graxos insaturados. Adicionalmente, a invenção diz respeito a uma composição oleosa e/ou de ácido graxo com um teor mais elevado de ácidos graxos C~ 20~ OU C~ 22~ poliinsaturados com pelo menos duas ligações duplas, e/ou a uma composição de triacilglicerol com um teor mais elevado dos referidos ácidos graxos poliinsaturados.
BR0208202-0A 2001-03-26 2002-03-26 ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit BR0208202A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0107510.0A GB0107510D0 (en) 2001-03-26 2001-03-26 New elongase gene and a process for the production of -9-polyunsaturated fatty acids
PCT/EP2002/003418 WO2002077213A2 (en) 2001-03-26 2002-03-26 New elongase gene and production of δ9-polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
BR0208202A true BR0208202A (pt) 2004-04-13

Family

ID=9911561

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208202-0A BR0208202A (pt) 2001-03-26 2002-03-26 ácido necleico isolado, sequência de aminoácidos, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou fração destes, composição oleaginosa, lipìdica ou de ácidos graxos, uso da mesma, anticorpo, sequência de nucleotìdeos anti-sentido, e, kit

Country Status (17)

Country Link
US (1) US7601889B2 (pt)
EP (1) EP1373519B1 (pt)
JP (1) JP2004531248A (pt)
CN (1) CN1537166A (pt)
AR (1) AR033449A1 (pt)
AT (1) ATE492641T1 (pt)
AU (1) AU2002310891B2 (pt)
BR (1) BR0208202A (pt)
CA (1) CA2442010C (pt)
DE (1) DE60238669D1 (pt)
DK (1) DK1373519T3 (pt)
EE (1) EE200300471A (pt)
ES (1) ES2383451T3 (pt)
GB (1) GB0107510D0 (pt)
IL (1) IL157562A0 (pt)
NO (1) NO20034276L (pt)
WO (1) WO2002077213A2 (pt)

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Also Published As

Publication number Publication date
ATE492641T1 (de) 2011-01-15
CN1537166A (zh) 2004-10-13
JP2004531248A (ja) 2004-10-14
WO2002077213A3 (en) 2003-03-13
US7601889B2 (en) 2009-10-13
AR033449A1 (es) 2003-12-17
IL157562A0 (en) 2004-03-28
NO20034276L (no) 2003-10-22
EP1373519A2 (en) 2004-01-02
DK1373519T3 (da) 2011-04-18
GB0107510D0 (en) 2001-05-16
NO20034276D0 (no) 2003-09-25
AU2002310891B2 (en) 2008-01-24
EE200300471A (et) 2003-12-15
US20050089981A1 (en) 2005-04-28
CA2442010A1 (en) 2002-10-03
WO2002077213A2 (en) 2002-10-03
EP1373519B1 (en) 2010-12-22
CA2442010C (en) 2013-07-30
DE60238669D1 (de) 2011-02-03
ES2383451T3 (es) 2012-06-21

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