BR0205771A - Processo simples para obtenção de (beta)-aescina a partir de castanha de cavalo indiano (aesculus indica) - Google Patents

Processo simples para obtenção de (beta)-aescina a partir de castanha de cavalo indiano (aesculus indica)

Info

Publication number
BR0205771A
BR0205771A BR0205771-9A BR0205771A BR0205771A BR 0205771 A BR0205771 A BR 0205771A BR 0205771 A BR0205771 A BR 0205771A BR 0205771 A BR0205771 A BR 0205771A
Authority
BR
Brazil
Prior art keywords
horse chestnut
obtaining
simple process
escine
beta
Prior art date
Application number
BR0205771-9A
Other languages
English (en)
Inventor
Bikram Singh
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Publication of BR0205771A publication Critical patent/BR0205771A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO SIMPLES PARA OBTENçãO DE <225>-AESCINA A PARTIR DE CASTANHA DE CAVALO INDIANO (AESCULUS INDICA)". A presente invenção se refere ao desenvolvimento de um processo simplificado para purificação de <225>-aescina a partir de castanha de cavalo indiano (Aesculus indica) por extração aquosa com álcool, solvente - partição de solvente, tratamento com base passando-se em seguida a camada orgânica através da alumina ácida em 2,0-3,0% de rendimento de pureza mínima de 90%.
BR0205771-9A 2002-03-25 2002-03-25 Processo simples para obtenção de (beta)-aescina a partir de castanha de cavalo indiano (aesculus indica) BR0205771A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2002/001208 WO2003080636A1 (en) 2002-03-25 2002-03-25 A simple process for obtaining beta-aescin from indian horse chestnut (aesculus indica)

Publications (1)

Publication Number Publication Date
BR0205771A true BR0205771A (pt) 2004-01-13

Family

ID=28053183

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0205771-9A BR0205771A (pt) 2002-03-25 2002-03-25 Processo simples para obtenção de (beta)-aescina a partir de castanha de cavalo indiano (aesculus indica)

Country Status (7)

Country Link
US (1) US20060030697A1 (pt)
EP (1) EP1487847B1 (pt)
AR (1) AR039120A1 (pt)
AU (1) AU2002247935B2 (pt)
BR (1) BR0205771A (pt)
DE (1) DE60214046T2 (pt)
WO (1) WO2003080636A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691780B2 (en) * 2005-02-17 2014-04-08 The Board Of Trustees Of The Leland Stanford Junior University Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
US20150110908A1 (en) 2013-10-21 2015-04-23 Ocusoft, Inc. Compositions, Kits, and Methods for Ameliorating Oculoplastic Post-Procedural Effects
CN104804060B (zh) * 2015-05-07 2017-01-18 西安蓝绿卓生物科技有限公司 一种七叶皂苷钠的制备方法、包含其的外用制剂及其应用
KR20200091925A (ko) * 2017-12-22 2020-07-31 주식회사 안지오랩 칠엽수 추출물을 포함하는 조성물
CN110862429A (zh) * 2018-08-28 2020-03-06 无锡凯夫制药有限公司 一种七叶皂苷钠的制备方法
CN113527379B (zh) * 2021-08-19 2022-09-20 海南师范大学 一种从婆罗子中提取分离纯化七叶皂苷的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151108A (en) * 1959-11-20 1964-09-29 Klinge Co Chem Pharm Fab Kryptoescin and process of making same
CH410283A (de) * 1960-06-14 1966-03-31 Klinge Co Chem Pharm Fab Verfahren zur Gewinnung von genuinem Aescin aus Extrakten der Rosskastanie
US3238190A (en) * 1963-10-23 1966-03-01 Madaus & Co K G Fa Dr Aescin recovery
AT274250B (de) * 1968-04-17 1969-09-10 Nattermann & Cie Arzneimittel Verfahren zur Gewinnung von wasserlöslichem Aescin aus Roßkastaniensamen und daraus hergestellten Extrakten
DE2530941C2 (de) * 1975-07-11 1991-10-10 Dr. Madaus & Co, 5000 Köln Verfahren zur Gewinnung von kristallinem Aescin und zur Herstellung von bestimmten Aescin-Salzen sowie Triethanolammoniumaescinat und dieses Salz enthaltende Arzneimittel
AT352909B (de) * 1976-08-12 1979-10-10 Lek Tovarna Farmacevtskih Verfahren zur isolierung von aescin aus fruechten der rosskastanie
EP0298148B1 (de) * 1987-07-10 1991-09-18 Herbe Wirkstoff GmbH Verfahren zur Gewinnung von Beta-aescinreichen Extrakten

Also Published As

Publication number Publication date
US20060030697A1 (en) 2006-02-09
AU2002247935A1 (en) 2003-10-08
EP1487847B1 (en) 2006-08-16
AR039120A1 (es) 2005-02-09
EP1487847A1 (en) 2004-12-22
DE60214046D1 (de) 2006-09-28
AU2002247935B2 (en) 2009-04-23
WO2003080636A1 (en) 2003-10-02
DE60214046T2 (de) 2007-02-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time